5 completed, 1 active not recruiting, 1 terminated. 3 Phase 4, 1 Phase 2, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 3 | Completed 2, Active not recruiting 1 |
| Phase 2 | 1 | Completed 1 |
| Phase 3 | 1 | Terminated 1 |
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contrave®/Mysimba®) on Major Adverse Cardiovascular Events (MACE) Naltrexone-Bupropion (NB) Combination, Placebo - Obesity | Phase 4 | Active not recruiting | Currax Pharmaceuticals | 8600 | 2024-01-03 | 2026-03-31 |
| Study to Assess the Safety and Efficacy of ONZETRA® Xsail® for the Acute Treatment of Episodic Migraine With or Without Aura in Adolescents sumatriptan nasal powder, Placebo - Acute Migraine With or Without Aura | Phase 3 | Terminated | Currax Pharmaceuticals | 159 | 2017-11-02 | 2023-07-24 |
| Assess the Effect of Zolpidem, Silenor & Placebo on Arousability, Ataxia/Balance & Cognition in Healthy Volunteers Silenor 6 mg, zolpidem 10 mg, Placebo - Healthy | Phase 4 | Completed | Currax Pharmaceuticals | 52 | 2015-01-01 | 2018-01-02 |
| Real-World Evidence on the Cardiovascular Safety of CONTRAVE® in the United States (U.S.) Obesity | Completed | Currax Pharmaceuticals | 31889 | 2014-09-01 | 2025-06-25 | |
| Drug Utilisation of Mysimba/Contrave Obesity | Completed | Currax Pharmaceuticals | 43324 | 2014-09-01 | 2023-10-18 | |
| Four Arm Safety & Efficacy With Antipyrine and Benzocaine Otic Solution in Children With Acute Otitis Media Antipyrine and Benzocaine otic solution, Antipyrine Otic Solution, Benzocaine Otic Solution - Acute Otitis Media | Phase 2 | Completed | Currax Pharmaceuticals | 112 | 2013-11-01 | 2024-08-07 |
| Does Treximet Improve Productivity and Patient Satisfaction Due to Sustained Response and Consistency of Response? Triptan, Treximet 85Mg-500Mg Tablet - Workplace Migraine Treatment | Phase 4 | Completed | The Cleveland Clinic | 60 | 2009-09-01 | 2018-05-01 |
Obesity (3) · Epilepsy (1) · Migraine Disorders (1) · Otitis Media (1)
Sumatriptan (2) · Antipyrine (1) · Doxepin (1) · Naproxen (1) · Tryptamines (1) · Zolpidem (1) · sumatriptan-naproxen (1)
United States (7)
Amy Agua, MD (1) · Bryan Harvey, MD (1) · Chris Drake, PhD (1) · Gerald Shockey, MD (1) · James Hendrick, MD (1) · James Peterson, MD (1) · Jennifer S Kriegler, MD (1) · John Ansely, MD (1) · Katie Julien, MD (1) · Michael Kyle, MD (1) · Shane Christensen, MD (1) · Stephanie Plunkett, MD (1) · Steven Goldberg, MD (1)
PMID 10221356, PMID 18431116, PMID 20625114, PMID 28575467, PMID 40104005