15 completed, 2 unknown, 1 recruiting, 1 terminated. 19 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 19 | Completed 15, Unknown 2, Recruiting 1, Terminated 1 |
Follow Osteopenia: new trials by email Literature Review of Osteopenia trials Research Report on Osteopenia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Zoledronic Acid for the Prevention of TDF-sparing ART-induced Bone Mass Density Loss in Treatment-naive HIV Positive Individuals Zoledronic Acid 5 mg/Bag 100 ml Inj - HIV Infected Individuals, Osteopenia | Phase 4 | Recruiting | Hadassah Medical Organization | 110 | 2024-12-09 | 2025-09-18 |
| A Study on the Prevention and Treatment of GIOP With Eldecalcitol Eldecalcitol capsules, Alfacalcidol tablets, Calcium carbonate tablets - Rheumatoid Arthritis, Osteoporosis | Phase 4 | Unknown | Chinese SLE Treatment And Research Group | 314 | 2024-06-01 | 2024-04-25 |
| Vitamin D Status and Bone Metabolism Status in Children With Congenital Epidermolysis Bullosa Vitamin D, Oral nutritional supplement - Bullosa Epidermolysis, Vitamin D Deficiency | Phase 4 | Unknown | National Medical Research Center for Children's Health, Russian Federation | 110 | 2020-11-21 | 2021-12-17 |
| Bone Mineral Density Changes in HIV-positive Females With Osteopenia Switching to Raltegravir raltegravir and atazanavir and ritonavir, tenofovir/emtricitabine and atazanavir and ritonavir - HIV Infection, Osteopenia | Phase 4 | Terminated | Giovanni Di Perri | 4 | 2014-09-01 | 2018-10-17 |
| Effect of Anti-diabetic Drugs on Bone Metabolism and Glycemic Variability Vildagliptin, Gliclazide MR - Type 2 Diabetes Mellitus, Menopause | Phase 4 | Completed | Centro de Diabetes Curitiba Ltda | 56 | 2012-12-01 | 2016-11-04 |
| Systematic Treatment After Successful Surgical Treatment for Primary Hyperparathyroidism With Strontium Ranelate Strontium Ranelate + Ca/Vitamin-D, Placebo - Primary Hyperparathyroidism, Osteopenia | Phase 4 | Completed | Medical University of Vienna | 63 | 2010-09-01 | 2015-01-21 |
| Efficacy of Monthly Ibandronate in Women With RA and Reduced Bone Mineral Density Receiving Long-term Steroids Ibandronate, Placebo - Rheumatoid Arthritis, Osteoporosis | Phase 4 | Completed | Yeong-Wook Song | 167 | 2010-04-01 | 2014-11-19 |
| Switch From Tenofovir to Raltegravir for Low Bone Mineral Density Raltegravir - HIV, Osteopenia | Phase 4 | Completed | St Vincent's Hospital, Sydney | 52 | 2009-10-01 | 2015-06-12 |
| Do Aromatase Inhibitors (AIs) Decrease Intestinal Calcium Absorption? Aromatase Inhibitor - Breast Cancer, Osteoporosis | Phase 4 | Completed | University of Wisconsin, Madison | 12 | 2009-01-01 | 2012-09-14 |
| High Dosage Vitamin D and Osteoporosis cholecalciferol (Vitamin D3), placebo - Osteoporosis, Osteopenia | Phase 4 | Completed | University Hospital of North Norway | 297 | 2007-02-01 | 2011-11-03 |
| Alendronate Prevents Microarchitectural Deterioration of Trabecular Bone in Early Postmenopausal Women alendronate sodium, placebo comparator - Osteopenia, Osteoporosis | Phase 4 | Completed | University of California, San Francisco | 53 | 2006-02-01 | 2013-08-14 |
| Does Treatment of Hypovitaminosis D Increase Calcium Absorption? Vitamin D - Osteoporosis, Osteopenia | Phase 4 | Completed | University of Wisconsin, Madison | 19 | 2005-01-01 | 2023-07-24 |
| Influence of Alfacalcidol on Falls in Osteopenic/Osteoporotic Postmenopausal Women (ALFA Study) alfacalcidol, placebo - Osteoporosis, Postmenopausal, Osteopenia | Phase 4 | Completed | Charite University, Berlin, Germany | 282 | 2003-06-01 | 2008-05-09 |
| FREE Study - Fracture Reduction Evaluation Balloon Kyphoplasty - Osteopenia, Osteoporosis | Phase 4 | Completed | Medtronic Spine LLC | 300 | 2003-02-01 | 2017-12-08 |
| Study to Investigate if Adding Lactulose to Vitamin D and Calcium Has an Effect on the Preservation of Bone in Postmenopausal Women Lactulose, Vitamin D, Calcium - Osteopenia | Phase 4 | Completed | Solvay Pharmaceuticals | 40 | 2003-01-01 | 2009-01-30 |
| Osteopenia and Renal Osteodystrophy: Evaluation and Management pamidronate - Osteopenia, Renal Osteodystrophy | Phase 4 | Completed | US Department of Veterans Affairs | 2002-10-01 | 2009-01-21 | |
| Comparison of Pamidronate With Zoledronic Acid for Transplant Related Bone Loss Prevention zoledronic acid vs pamidronate - Osteopenia, Complications of Heart-lung Transplant | Phase 4 | Completed | Bayside Health | 56 | 2002-10-01 | 2013-12-05 |
| Bone Loss in Premenopausal Women With Depression Alendronate - Depression, Healthy | Phase 4 | Completed | National Institute of Mental Health (NIMH) | 220 | 2000-08-10 | 2017-07-02 |
| Comparison of Tibolone and Raloxifene on Bone Mineral Density in Osteopenic Postmenopausal Women (P06090) tibolone, raloxifen - Osteopenia | Phase 4 | Completed | Organon and Co | 324 | 2000-07-31 | 2024-08-15 |
Bone Diseases, Metabolic (19) · Osteoporosis (13) · Arthritis, Rheumatoid (2) · Fractures, Bone (2) · HIV Infections (2) · Vitamin D Deficiency (2) · Back Pain (1) · Bone Neoplasms (1) · Bone Resorption (1) · Breast Neoplasms (1) · Chronic Kidney Disease-Mineral and Bone Disorder (1) · Depression (1) · Depressive Disorder, Major (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1)
Bone Diseases (19) · Metabolic Diseases (19) · Musculoskeletal Diseases (19) · Nutritional and Metabolic Diseases (19) · Immune System Diseases (5) · Endocrine System Diseases (4) · Pathological Conditions, Signs and Symptoms (4) · Skin and Connective Tissue Diseases (4) · Avitaminosis (3) · Deficiency Diseases (3) · Malnutrition (3) · Nutrition Disorders (3) · Parathyroid Diseases (3) · Urogenital Diseases (3) · Wounds and Injuries (3)
Vitamin D (3) · Alendronate (2) · Raltegravir Potassium (2) · alfacalcidol (2) · Aromatase Inhibitors (1) · Atazanavir Sulfate (1) · Calcium (1) · Calcium Carbonate (1) · Cholecalciferol (1) · Dietary Supplements (1) · Emtricitabine (1) · Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination (1) · Ergocalciferols (1) · Gliclazide (1) · Ibandronic Acid (1)
University of Wisconsin, Madison (2) · Bayside Health (1) · Centro de Diabetes Curitiba Ltda (1) · Charite University, Berlin, Germany (1) · Chinese SLE Treatment And Research Group (1) · Giovanni Di Perri (1) · Hadassah Medical Organization (1) · Medical University of Vienna (1) · Medtronic Spine LLC (1) · National Institute of Mental Health (NIMH) (1) · National Medical Research Center for Children's Health, Russian Federation (1) · Organon and Co (1) · Solvay Pharmaceuticals (1) · St Vincent's Hospital, Sydney (1) · US Department of Veterans Affairs (1)
United States (5) · Australia (1) · Austria (1) · Brazil (1) · China (1) · Germany (1) · Israel (1) · Italy (1) · Norway (1) · Russia (1) · South Korea (1) · Spain (1)
Karen E Hansen, MD (2) · Andre GD Vianna, MD (1) · Andrew D Carr, Professor (1) · Bruno Niederle, Prof., MD (1) · Dieter Felsenberg, Prof. Dr. (1) · Duncan J Topliss, MD (1) · Eynat Kedem, Doctor (1) · Giovanni Di Perri, MD, PhD (1) · Hila Elinav, Doctor (1) · Itzchak Levy, Proffesor (1) · Mengtao Li, MD (1) · Rolf Jorde, Ph.D, M.D (1) · Thomas M Link, MD (1)
PMID 18039992, PMID 18256777, PMID 19246088, PMID 21912321, PMID 22235252, PMID 22350731, PMID 22443312, PMID 22848407, PMID 23446769, PMID 28161119, PMID 28515791
2008 (1)