12 completed, 6 unknown, 2 terminated, 1 withdrawn. 21 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 21 | Completed 12, Unknown 6, Terminated 2, Withdrawn 1 |
Follow Osteoarthritis of the Knee: new trials by email Literature Review of Osteoarthritis of the Knee trials Research Report on Osteoarthritis of the Knee
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Functional and Clinical Outcomes of Hyaluronic Acid and Steroid Injections in Bilateral Knee Osteoarthritis Sodium hyaluronate (hyaluronic acid), Methylprednisolone Acetate Injection - Osteoarthritis (OA) of the Knee, Osteoarthritis | Phase 4 | Completed | Edin Mešanović | 65 | 2023-01-01 | 2024-12-05 |
| Identification of Sarcopenia in Knee Osteoarthritis With Ultrasonography and Evaluation of Muscle Architecture Change by Ultrasonography After Isokinetic Exercise Program Knee strengthening exercises with isokinetic dynamometer, Strengthening around the knees with home exercise programe - Osteoarthritis of the Knee, Sarcopenia | Phase 4 | Unknown | Sema Dağcı | 60 | 2021-08-18 | 2021-08-25 |
| Effects of Perioperative Intravenous Dexamethasone on the Severity of Persistent Postsurgical Pain After Total Knee Arthroplasty : A Prospective, Randomized, Double-blind, Placebo-controlled Trial Dexamethasone, Normal saline solution - Osteoarthritis of the Knee | Phase 4 | Unknown | Chiang Mai University | 70 | 2016-10-01 | 2016-10-10 |
| Outcomes of Injections in Patients Waiting for Total Knee Replacement Hylan G-F 20, Triamcinolone - Osteoarthritis of the Knee | Phase 4 | Unknown | Universidade Federal Fluminense | 120 | 2015-09-01 | 2017-03-27 |
| To Compare the Efficacy and Safety of LAYLA in Osteoarthritis Patients of the Knee LAYLA tablet, CENATONE tablet - Osteoarthritis of the Knee | Phase 4 | Completed | PMG Pharm Co., Ltd | 134 | 2014-02-24 | 2017-09-20 |
| Efficacy and Safety of Imotun Capsule in Osteoarthritis of the Knee Imotun, Placebo - Osteoarthritis of the Knee | Phase 4 | Completed | Chong Kun Dang Pharmaceutical | 287 | 2013-01-01 | 2017-03-27 |
| The Study to Evaluate Efficacy and Safety of Imotun Capsule in Osteoarthritis of the Knee Imotun capsule, Imotun capsule placebo - Osteoarthritis of the Knee | Phase 4 | Completed | Chong Kun Dang Pharmaceutical | 234 | 2012-12-01 | 2015-04-30 |
| To Compare the Efficacy and Safety of LAYLA in Osteoarthritis Patients LAYLA tablet, JOINS tablet - Osteoarthritis of the Knee | Phase 4 | Completed | PMG Pharm Co., Ltd | 124 | 2012-10-01 | 2013-10-14 |
| Clinical and Stereoradiological Comparison of the Results After Primary Cemented Total Knee Arthroplasty Inserted With or Without the Use of a Tourniquet tourniquet, no tourniquet - Osteoarthritis of the Knee | Phase 4 | Withdrawn | Hvidovre University Hospital | 2012-01-01 | 2015-03-18 | |
| Efficacy of Spearmint Tea in Relieving Osteoarthritis of the Knee Commercially spearmint tea, High Rosmarinic Acid Spearmint Tea - Osteoarthritis of the Knee | Phase 4 | Completed | University of Guelph | 49 | 2011-07-01 | 2013-01-23 |
| Efficacy and Safety of 3 Different Dosage Regimens of Hyaluronic Acid in Patients With Knee Osteoarthritis (OA) Hyaluronic acid 5 x 2.5 ml, Hyaluronic acid 1 x 5 ml, Hyaluronic acid 2 x 5 ml - Osteoarthritis of the Knee | Phase 4 | Completed | Tedec-Meiji Farma, S.A. | 45 | 2010-11-01 | 2014-03-03 |
| Prophecy Guide Outcomes in Total Knee Replacement Surgery Prophecy Technique, Navigation System - Osteoarthritis of the Knee, Total Knee Replacement | Phase 4 | Unknown | Global Orthopaedic Technology | 188 | 2010-08-01 | 2010-07-29 |
| Development of Knee Osteoarthritis After Arthroscopic Partial Resection of Degenerative Meniscus Tear Arthroscopic partial meniscectomy, Arthroscopy (diagnostic) - Osteoarthritis of the Knee, Arthroscopy | Phase 4 | Unknown | Tampere University | 160 | 2010-01-01 | 2015-01-21 |
| A Comparative Study of Knee Systems Total Knee Arthroplasty with Custom Cutting Blocks, Total Knee Arthroplasty via Computer Assisted Surgery - Osteoarthritis of the Knee | Phase 4 | Completed | Foundation for Southwest Orthopedic Research | 60 | 2009-09-01 | 2011-04-08 |
| Efficacy and Safety of Prednisolone and Chloroquine Add on Therapy in Osteoarthritis of the Knee Glucosamine and chondroitin sulfate, glucosamine and chondroitin sulfate plus Prednisolone, Glucosamine and Chondroitin sulfate plus Chloroquine - Osteoarthritis of the Knee | Phase 4 | Completed | Ardabil University of Medical Sciences | 230 | 2009-02-01 | 2010-04-30 |
| Efficacy of Multimodal Peri- and Intraarticular Drug Injections in Total Knee Arthroplasty ropivacaine, adrenaline, ketorolac - Osteoarthritis of the Knee | Phase 4 | Completed | Asker & Baerum Hospital | 102 | 2007-11-01 | 2011-08-08 |
| Treatment Of Knee Osteoarthritis With Intra-Articular Infliximab Infliximab, Placebo, Standard of Care: Methylprednisolone acetate - Osteoarthritis of the Knee | Phase 4 | Completed | Herbert Lindsley, MD | 16 | 2007-07-01 | 2018-02-08 |
| The Effect of Intraaricular Knee Injections of Hyaluronic Acid (HA) on Bone and Cartilaginous Debris, as a Therapeutic Indicator Sodium hyaluronate (hyaluronic acid) - Osteoarthritis of the Knee | Phase 4 | Unknown | Assaf-Harofeh Medical Center | 60 | 2007-03-01 | 2007-01-18 |
| A Gender-Specific Posterior Cruciate-Substituting High-Flexion Knee Prosthesis Does Not Improve Fit and Function Standard LPS flex TKA, Gender specific LPS -Flex TKA - Osteoarthritis of the Knee, Female | Phase 4 | Completed | Ewha Womans University | 88 | 2006-11-01 | 2009-06-12 |
| MINIMALLY INVASIVE SURGERY in Total Knee Arthroplasty surgical technique - Osteoarthritis of the Knee | Phase 4 | Terminated | Smith & Nephew Orthopaedics AG | 2004-10-01 | 2014-05-23 |
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Osteoarthritis, Knee (21) · Osteoarthritis (5) · Arthritis (1) · Sarcopenia (1)
Joint Diseases (21) · Musculoskeletal Diseases (21) · Rheumatic Diseases (21) · Arthritis (20) · Osteoarthritis (16) · Atrophy (1) · Muscular Atrophy (1) · Nervous System Diseases (1) · Neurologic Manifestations (1) · Neuromuscular Manifestations (1) · Pathological Conditions, Anatomical (1) · Pathological Conditions, Signs and Symptoms (1) · Signs and Symptoms (1)
Hyaluronic Acid (2) · Arthroplasty, Replacement, Knee (1) · Arthroscopy (1) · Bupivacaine (1) · Capsules (1) · Celecoxib (1) · Chloroquine (1) · Chondroitin Sulfates (1) · Dexamethasone (1) · Epinephrine (1) · Fentanyl (1) · Glucosamine (1) · Infliximab (1) · Ketorolac (1) · Ketorolac Tromethamine (1)
Chong Kun Dang Pharmaceutical (2) · PMG Pharm Co., Ltd (2) · Ardabil University of Medical Sciences (1) · Asker & Baerum Hospital (1) · Assaf-Harofeh Medical Center (1) · Chiang Mai University (1) · Edin Mešanović (1) · Endo USA Inc., a Keenova Therapeutics Company (1) · Ewha Womans University (1) · Foundation for Southwest Orthopedic Research (1) · Global Orthopaedic Technology (1) · Herbert Lindsley, MD (1) · Hvidovre University Hospital (1) · Sema Dağcı (1) · Smith & Nephew Orthopaedics AG (1)
South Korea (5) · United States (3) · Australia (1) · Bosnia and Herzegovina (1) · Brazil (1) · Canada (1) · Denmark (1) · Finland (1) · Germany (1) · Iran (1) · Israel (1) · Norway (1) · Spain (1) · Thailand (1) · Turkey (Türkiye) (1)
Alejandro Escudero (1) · Alison M Duncan, Ph.D., R.D. (1) · Amanda J Wright, Ph.D. (1) · Anders Troelsen, M.D, Ph.D (1) · Andre Campos (1) · Byung Woo Min (1) · Chul Won Ha (1) · Dae Hyun Yoo (1) · Han Jun Lee, MD (1) · Herbert Lindsley, MD (1) · Hugh English (1) · Jae Hyup Lee (1) · Jeong Ku Ha, MD (1) · Jong Min Kim, MD (1) · Marina Jastan, MD (1)
PMID 20736233, PMID 24810539, PMID 25058311, PMID 26821189, PMID 29035179, PMID 31937344, PMID 32855201, PMID 39277028, PMID 39702151