13 recruiting, 8 not yet recruiting, 3 completed, 1 unknown. 13 Not applicable, 3 Phase 2, 2 Phase 3, 1 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 13 | Not yet recruiting 6, Recruiting 5, Unknown 1, Withdrawn 1 |
| Phase 2 | 3 | Completed 1, Not yet recruiting 1, Recruiting 1 |
| Phase 3 | 2 | Recruiting 2 |
| Phase 1 | 1 | Not yet recruiting 1 |
Follow OSA - Obstructive Sleep Apnea: new trials by email Literature Review of OSA - Obstructive Sleep Apnea trials Research Report on OSA - Obstructive Sleep Apnea
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| BioMAD - A Non-inferiority Study BioMAD - OSA - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | University of Lausanne Hospitals | 20 | 2026-11-01 | 2026-09-28 |
| PMOS in OSA Pilot Study Continuous Positive Airway Pressure (CPAP) - PCOS, PCOS (Polycystic Ovary Syndrome) | Not applicable | Recruiting | University of Chicago | 10 | 2026-10-01 | 2026-10-13 |
| The Optimal One-Month Dosing of Lemborexant for Moderate Obstructive Sleep Apnea (OSA) Patients With Low Arousal Threshold Lemborexant 5 MG [Dayvigo] Period 1, Placebo Period 1, Lemborexant 5 MG [Dayvigo] Period 2 - OSA - Obstructive Sleep Apnea | Phase 1 / Phase 2 | Not yet recruiting | Chulalongkorn University | 36 | 2026-09-01 | 2026-07-06 |
| Miniscrew-Assisted Rapid Palatal Expansion for Obstructive Sleep Apnea Miniscrew-Assisted Rapid Palatal Expansion, Standard Care (in control arm) - OSA - Obstructive Sleep Apnea, Palatal Expansion Technique | Not applicable | Not yet recruiting | University of Malaya | 24 | 2026-08-01 | 2026-07-29 |
| Effects of Surgery on Oral Frailty and Dysphagia in Patients With Obstructive Sleep Apnea Upper airway surgery for OSA, Non-surgical management - OSA - Obstructive Sleep Apnea, Dysphagia | Recruiting | National Sun Yat-sen University | 450 | 2026-06-12 | 2026-10-19 | |
| Serene Sleep Palatal Implant System Clinical Confirmatory Trial in Participants Who Snore or Are Diagnosed With Mild-to-moderate Obstructive Sleep Apnea (OSA). Palatal Implant System - Snoring, OSA - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | Serene Sleep, Inc. | 26 | 2026-06-01 | 2026-06-01 |
| Mandibular Advancement to Reduce Ventricular Load and Improve Quality-of-life in Heart Failure Mandibular advancement device, Mandibular advancement device (Sham) - Heart Failure, OSA - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | National University Hospital, Singapore | 328 | 2026-05-01 | 2026-03-10 |
| A Study of XW003 in Obese Participants With Obstructive Sleep Apnea Receiving Positive Airway Pressure Therapy XW003 injection, placebo with matching volume - OSA - Obstructive Sleep Apnea, Obesity | Phase 3 | Recruiting | Hangzhou Sciwind Biosciences Co., Ltd. | 140 | 2026-03-02 | 2026-08-28 |
| Evaluation of a Wearable PAP Device in a Tethered Configuration for the Treatment of Obstructive Sleep Apnoea. Positive Airway Pressure - OSA - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | ResMed | 15 | 2026-03-01 | 2026-02-19 |
| A Study of XW003 in Obese Participants With Obstructive Sleep Apnea But Not Receive Positive Airway Pressure Therapy XW003 injection, placebo with matching volume - OSA - Obstructive Sleep Apnea, Obesity | Phase 3 | Recruiting | Hangzhou Sciwind Biosciences Co., Ltd. | 140 | 2026-02-09 | 2026-08-28 |
| Comparative Study of CPAP Predictive Equations and In-laboratory Manual Titration in Thai Patients With Obstructive Sleep Apnea Sleep test, Predictive equations of continuous positive airway pressure (CPAP) - OSA - Obstructive Sleep Apnea | Recruiting | Thammasat University | 150 | 2026-02-01 | 2026-04-17 | |
| The Correlation Between Obstructive Sleep Apnea-Related Nocturnal Hypoxemia Parameters and Coronary Microvascular Dysfunction: A Prospective Cohort Study (SLEEP-CMD) Polysomnography - OSA - Obstructive Sleep Apnea, Coronary Microvascular Dysfunction (CMD) | Not yet recruiting | Beijing Anzhen Hospital | 560 | 2025-12-30 | 2026-01-02 | |
| Effects of Eszopiclone and Lemborexant in People With OSA With a Low Arousal Threshold Who Have Difficulty Sleeping Eszopiclone 3 mg, Placebo, Lemborexant 10mg - OSA - Obstructive Sleep Apnea | Phase 2 | Recruiting | Flinders University | 15 | 2025-10-31 | 2026-09-02 |
| Obstructive Sleep Apnoea and Difficult Asthma (OSADA) Continuous positive airway pressure (CPAP) - Asthma (Diagnosis), OSA - Obstructive Sleep Apnea | Not applicable | Recruiting | St. James's Hospital, Ireland | 80 | 2025-09-01 | 2026-05-26 |
| Effect of Weight Loss From ESG Plus Lifestyle Changes vs. Lifestyle Changes Alone in Sleep Apnea Patients Endoscopic Sleeve Gastropathy, Lifestyle Modification alone - OSA - Obstructive Sleep Apnea | Not applicable | Recruiting | Asian Institute of Gastroenterology, India | 74 | 2025-08-19 | 2025-12-19 |
| SMARTPHONE APPLICATION HOME-BASED EXERCISES IN OBSTRUCTIVE SLEEP APNEA IN JEDDAH CPAP device, CPAP device and exercise, Exercise - OSA - Obstructive Sleep Apnea | Not applicable | Not yet recruiting | King Abdulaziz University | 60 | 2025-05-25 | 2025-05-02 |
| Impact of Atrial Fibrillation Ablation on Sleep Parameters. Atrial Fibrillation (AF), OSA - Obstructive Sleep Apnea | Recruiting | Primula Clinics | 100 | 2025-03-20 | 2025-12-02 | |
| The Effect of Systemic Nonsteroidal Anti-inflammatory Drugs (NSAIDs) Vs Intraoperative Infiltration of Steroids in Tonsillar Bed Following Tonsillectomy on Post Tonsillectomy Pain. Dexamethasone, NSAIDs, Control (Standard treatment) - Tonsillitis Chronic, Tonsillitis Recurrent | Not applicable | Recruiting | Ain Shams University | 75 | 2025-03-08 | 2025-06-25 |
| Stroke and CPAP Outcome Study 3 Randomized Controlled Trial CPAP device, CPAP technical support, Phone follow-up for adherence feedback and self-management skills - Stroke Patients, CPAP | Not applicable | Recruiting | University of Washington | 250 | 2025-01-15 | 2026-08-13 |
| Primary Prevention Long-term Registry Study in OSA and Hypertension. Survival Analysis 2010-2022 Positive airway pressure (PAP) - Hypertension, OSA - Obstructive Sleep Apnea | Completed | Vastra Gotaland Region | 148467 | 2025-01-01 | 2025-05-23 |
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Sleep Apnea, Obstructive (26) · Sleep Apnea Syndromes (4) · Obesity (2) · Snoring (2) · Airway Obstruction (1) · Apnea (1) · Asthma (1) · Atrial Fibrillation (1) · Coronary Artery Disease (1) · Deglutition Disorders (1) · Disease (1) · Heart Failure (1) · Hypertension (1) · Polycystic Ovary Syndrome (1) · Sleepiness (1)
Dyssomnias (26) · Nervous System Diseases (26) · Respiration Disorders (26) · Respiratory Tract Diseases (26) · Sleep Disorders, Intrinsic (26) · Sleep Wake Disorders (26) · Apnea (25) · Sleep Apnea Syndromes (22) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (5) · Cardiovascular Diseases (4) · Heart Diseases (3) · Signs and Symptoms, Respiratory (3) · Body Weight (2) · Nutrition Disorders (2)
Continuous Positive Airway Pressure (2) · Polysomnography (2) · lemborexant (2) · Acetaminophen (1) · Anti-Inflammatory Agents, Non-Steroidal (1) · Atomoxetine Hydrochloride (1) · Decision Support Techniques (1) · Dexamethasone (1) · Eszopiclone (1) · Exercise (1) · Exercise Therapy (1) · Motivational Interviewing (1) · Occlusal Splints (1) · Palatal Expansion Technique (1) · Standard of Care (1)
Hangzhou Sciwind Biosciences Co., Ltd. (2) · Ain Shams University (1) · Apnimed (1) · Asian Institute of Gastroenterology, India (1) · Beijing Anzhen Hospital (1) · Chulalongkorn University (1) · Comenius University (1) · Flinders University (1) · Fondazione Don Carlo Gnocchi ETS (1) · IRCCS San Raffaele (1) · King Abdulaziz University (1) · National Sun Yat-sen University (1) · National University Hospital, Singapore (1) · Primula Clinics (1) · ResMed (1)
United States (4) · China (3) · Italy (2) · Taiwan (2) · Thailand (2) · Australia (1) · Egypt (1) · India (1) · Ireland (1) · Poland (1) · Singapore (1) · Slovakia (1) · Sweden (1)
Danny J Eckert, PhD (1) · Dean Wu, MD, PhD (1) · Devin Brown, MD, MS (1) · Linong Ji, Dr (1) · Narongkorn Saiphoklang (1) · Peter Turcani, prof. MD PhD. (1) · Qingyun Li, Dr (1) · Raj C Dedhia, MD (1) · Rakesh Kalapala, MD, DNB (1) · Sandeep Khot, MD, MPH (1) · Sarocha Vivatvakin, MD (1) · Sven Svedmyr, MD (1) · Xueling Zhu (1)
PMID 12833183, PMID 18797117, PMID 19960649, PMID 21217962, PMID 23051618, PMID 23145885, PMID 24731756, PMID 27878543, PMID 28162150, PMID 31881487, PMID 32883901, PMID 33590375, PMID 34230571, PMID 34797460, PMID 36968331, PMID 37812772, PMID 38351662, PMID 39226674, PMID 39589660, PMID 39716408, PMID 39998447
R01HL164394 (1)