57 completed, 11 unknown, 9 recruiting, 7 not yet recruiting. 44 Not applicable, 8 Phase 3, 5 Phase 2, 4 Phase 1, 3 Phase 4.
Follow Sleepiness: new trials by email Literature Review of Sleepiness trials Research Report on Sleepiness
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Predicting Declines in Attention and Memory During a Prolonged Mental Task Individually Calibrated Time Load Dual-back Task With Seated Rest - Mental Fatigue, Cognitive Performance | Not applicable | Not yet recruiting | DSW Ideis University | 250 | 2026-12-01 | 2026-10-16 |
| Sleep, Mindfulness, and Shift-Level Safety Performance in Perianesthesia Nurses Sleep, Mindfulness, and Shift-Level Safety Observation Toolkit - Sleep, Fatigue | Not yet recruiting | Volkan Gokmen | 300 | 2026-10-01 | 2026-09-24 | |
| Hypersomnia in the Paediatric Population Sleepness and wakeness scale, Polysomnography, Actimetry - Wakefulness Disorder, Narcolepsy | Not applicable | Not yet recruiting | University Hospital, Montpellier | 760 | 2026-09-01 | 2026-08-14 |
| A Study to Evaluate the Efficacy, Safety and Tolerability of ALKS 2680 in Adults With Narcolepsy Type 1 (Brilliance NT1 - 304) ALKS 2680 Dose 1, ALKS 2680 Dose 2, Placebo - Narcolepsy Type 1 | Phase 3 | Recruiting | Alkermes, Inc. | 150 | 2026-08-13 | 2026-10-07 |
| A Study to Investigate the Effects of Cleminorexton Compared With Placebo in the Treatment of Participants With Central Disorders of Hypersomnolence cleminorexton, Placebo - Narcolepsy Type 1, Narcolepsy Type 2 | Phase 2 / Phase 3 | Recruiting | Centessa Pharmaceuticals (UK) Limited | 222 | 2026-05-29 | 2026-10-02 |
| TESTING AN MTM THEORY-BASED INTERVENTION ON REDUCING DROWSY DRIVING BEHAVIOR, "STAY AWAKE, STAY ALIVE ©," AMONG COLLEGE STUDENTS MTM Theory based intervention, Standard AAA Knowledge based - Drowsiness, Sleep Deprivation | Not applicable | Enrolling by invitation | University of Nevada, Las Vegas | 72 | 2026-04-07 | 2026-05-26 |
| Homeostatic Regulation of Sleep in Short Sleepers Actigraphy, Polysomnographie (PSG 128), TILE test - Short Sleepers, Normal Sleepers | Not applicable | Not yet recruiting | University Hospital, Montpellier | 75 | 2026-04-01 | 2026-05-13 |
| Obstructive Sleep Apnea Therapeutic Intervention for REsiDual Sleepiness Active tPBM - Obstructive Sleep Apnea, Sleepiness | Not applicable | Recruiting | NYU Langone Health | 22 | 2026-01-12 | 2026-01-14 |
| Perceived Barriers and Facilitators to Physical Activity in Turkish Youth Healthy Participants | Completed | Istinye University | 318 | 2025-12-28 | 2026-05-12 | |
| Shift Hours' Impact on Fatigue and Tracking of Eye Dynamics Electroencephalogram, Actigraphy, Eye Tracking - Sleep Deprivation, Sleepiness | Not applicable | Not yet recruiting | IMADIS Technologies et Services | 40 | 2025-09-15 | 2025-09-25 |
| Effect of Different Foot Baths on Postpartum Insomnia and Fatigue Peppermint oil footbath, Warm Water Footbath - Postpartum | Not applicable | Not yet recruiting | University of Yalova | 90 | 2025-09-01 | 2025-08-15 |
| Exploring Biological Markers of Driver Fatigue for Enhanced Road Safety Drowsiness, Sleepiness | Completed | University of Zurich | 511 | 2025-08-29 | 2026-03-25 | |
| VR-based Multi-dimensional Intervention on Cognitive Function, With AI-agents VR-based multi-dimensional intervention - Dementia, Sleepiness | Not applicable | Not yet recruiting | Hong Kong University of Science and Technology | 60 | 2025-07-15 | 2025-07-14 |
| Impact of Atrial Fibrillation Ablation on Sleep Parameters. Atrial Fibrillation (AF), OSA - Obstructive Sleep Apnea | Recruiting | Primula Clinics | 100 | 2025-03-20 | 2025-12-02 | |
| Effect of Lavender on Sleep Quality and Insomnia Severity in Patients lavender sachet group, control group - Insomnia, Psychophysiological | Not applicable | Completed | Saglik Bilimleri Universitesi Gulhane Tip Fakultesi | 68 | 2025-01-21 | 2025-09-16 |
| Assessment of Tiredness During Awake Resection of Intracerebral Tumors Karolinska Sleepiness Scale, KSS - Brain Tumor Adult, Awake Surgery | Recruiting | Region Skane | 10 | 2024-11-11 | 2025-04-10 | |
| Study of Psychological, Sociological and Professional Factors Associated With Maintenance of Wakefulness Test STAI (State-Trait Anxiety Inventory) Scale : Psychological inventory of 20 self-report items on a 4-point scale - Narcolepsy, Obstructive Sleep Apnea (OSA) | Completed | Hospices Civils de Lyon | 103 | 2024-10-18 | 2026-06-05 | |
| Effect of Intermittent and Continuous Theta Burst Stimulation on Sleep, Daytime Sleepiness, and Fatigue in Depression iTBS, cTBS, Sham - Unipolar Depression, Bipolar Disorder | Not applicable | Recruiting | Jakub Antczak | 90 | 2024-05-15 | 2024-10-15 |
| Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis Light therapy - Progressive Multiple Sclerosis | Phase 1 | Enrolling by invitation | University of Texas Southwestern Medical Center | 20 | 2024-04-18 | 2025-12-31 |
| Lifestyle Coaching for Fatigue Mitigation in Emergency Medicine Residents Personalized lifestyle coaching and educational handout, Handout - Lifestyle, Healthy, Sleepiness | Not applicable | Withdrawn | Stanford University | 2024-03-31 | 2026-04-24 |
Showing 20 of 90. Sign in to see all of them.
Fatigue (26) · Sleep Apnea, Obstructive (16) · Sleep Initiation and Maintenance Disorders (13) · Disorders of Excessive Somnolence (8) · Anxiety Disorders (7) · Narcolepsy (7) · Sleep Deprivation (7) · Sleep Wake Disorders (7) · Depression (6) · Sleep Apnea Syndromes (6) · Idiopathic Hypersomnia (4) · Sleep Disorders, Circadian Rhythm (4) · Alzheimer Disease (3) · Apnea (3)
Pathological Conditions, Signs and Symptoms (90) · Signs and Symptoms (90) · Nervous System Diseases (59) · Mental Disorders (47) · Dyssomnias (44) · Sleep Wake Disorders (41) · Sleep Disorders, Intrinsic (38) · Neurologic Manifestations (26) · Respiratory Tract Diseases (22) · Behavior (17) · Respiration Disorders (17) · Apnea (15) · Sleep Apnea Syndromes (12) · Behavioral Symptoms (10) · Central Nervous System Diseases (9)
Modafinil (5) · Surveys and Questionnaires (5) · Control Groups (3) · Actigraphy (2) · Blood Specimen Collection (2) · Aprepitant (1) · Cognitive Behavioral Therapy (1) · Continuous Positive Airway Pressure (1) · Cross-Sectional Studies (1) · Diet Therapy (1) · Diet, Plant-Based (1) · Electroencephalography (1) · Eye-Tracking Technology (1) · Lenalidomide (1) · Lorazepam (1)
University Hospital, Bordeaux (5) · Brigham and Women's Hospital (3) · University Hospital, Montpellier (3) · VA Office of Research and Development (3) · Assistance Publique - Hôpitaux de Paris (2) · Celgene (2) · Harmony Biosciences Management, Inc. (2) · Hospices Civils de Lyon (2) · Mayo Clinic (2) · Stanford University (2) · University of Michigan (2) · University of Zurich (2) · Alkermes, Inc. (1) · Alza Corporation, DE, USA (1) · Associação Fundo de Incentivo à Pesquisa (1)
United States (34) · France (16) · Turkey (Türkiye) (5) · Poland (4) · Switzerland (4) · Japan (3) · Belgium (2) · Brazil (2) · Greece (2) · Sweden (2) · Taiwan (2) · Armenia (1) · Australia (1) · Canada (1) · China (1)
Susmita Chowdhuri, MD MS (3) · Charles Czeisler, PH.D., M.D. (2) · Pierre Philip, Pr (2) · Al'ai Alvarez, MD (1) · Aleksandar Videnovic, MD, MS (1) · Ava K. Bittner, O.D., Ph.D. (1) · Bernie Sunwoo, MBBS (1) · Bogdan Stefanowski, MD (1)
PMID 18430310, PMID 19573495, PMID 21063868, PMID 22832068, PMID 23094031, PMID 25224885, PMID 25610980, PMID 25658148, PMID 25771402, PMID 25978152, PMID 25979100, PMID 26305869, PMID 27388752, PMID 28241159, PMID 28583143, PMID 28745520, PMID 29017780, PMID 30691989, PMID 31319726, PMID 33679469, PMID 34753859, PMID 35074887, PMID 35149627, PMID 35855534, PMID 36810100, PMID 36861433, PMID 38367595, PMID 39338040, PMID 39585451
2019 (1), R01CA151445 (1), R01HL105999 (1), R01HL146059 (1), R21NR011387 (1)