8 completed, 6 recruiting, 2 active not recruiting, 2 not yet recruiting. 8 Not applicable, 2 Phase 2, 2 Phase 4, 1 Phase 1.
Follow Organ Failure, Multiple: new trials by email Literature Review of Organ Failure, Multiple trials Research Report on Organ Failure, Multiple
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety, Tolerability and Performance of the NucleoCapture Extracorporeal Therapeutic Apheresis Device in the Reduction of Circulating cfDNA/NETs in Subjects With Pancreatitis NucleoCapture device - Acute Pancreatitis, Organ Failure, Multiple | Not applicable | Not yet recruiting | Liverpool University Hospitals NHS Foundation Trust | 20 | 2025-12-01 | 2025-03-20 |
| ICU Background Early Awareness for Critical deterioratiON ICU Beacon - Respiratory Failure, Circulatory Failure | Recruiting | ETH Zurich | 1962 | 2025-12-01 | 2026-06-15 | |
| Sivelestat Treatment for Postoperative Organ Protection in Type A Aortic Dissection Conventional treatment, Sivelestat sodium, Placebo - Type A Aortic Dissection, Organ Failure, Multiple | Phase 4 | Not yet recruiting | Shanghai Zhongshan Hospital | 236 | 2025-09-01 | 2025-09-05 |
| Controlled Terminal Reperfusion With Cold Preservation Solution in the cDCD III Donor Transplant Patients, Organ Failure, Multiple | Completed | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 20 | 2025-03-17 | 2026-02-19 | |
| Rectal Indomethacin as Early Treatment for Acute Pancreatitis (INDOMAP Trial) Indomethacin SR, Placebos - Acute Pancreatitis, Complication | Phase 4 | Recruiting | Peking Union Medical College Hospital | 1504 | 2024-12-01 | 2025-06-15 |
| Evaluation of the Efficiency of Intermittent Enteral Nutrition on Multi-organ Failure From Patients With Mechanical Ventilation in Intensive Care Unit Intermittent enteral nutrition - Intermittent Fasting, Septic Shock | Not applicable | Completed | University Hospital, Rouen | 174 | 2024-07-09 | 2026-09-28 |
| The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients traditional Chinese medicine, Routine ICU care, historical Routine ICU care - Organ Failure, Multiple, Indigestion | Not applicable | Recruiting | China Medical University Hospital | 350 | 2024-05-07 | 2024-06-11 |
| Impact of Fourier Transform Infrared Spectroscopy (FTIRS) in ICUs FTIR results - Organ Failure, Multiple | Not applicable | Recruiting | University Hospital, Caen | 900 | 2024-01-08 | 2025-07-24 |
| Electronic Archive of Internal Medicine for the Treatment of Severe Organ Failure and Liver Transplantation-MITIGO Organ Failure, Multiple, LIVER TRANSPLANTATION | Recruiting | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 10000 | 2023-10-21 | 2025-01-17 | |
| Trial of Indication-Based Transfusion of Red Blood Cells in ECMO Red blood cell transfusion - Extracorporeal Membrane Oxygenation, Red Blood Cell Transfusion | Not applicable | Active not recruiting | Boston Children's Hospital | 228 | 2023-04-14 | 2026-07-02 |
| Heterogeneity of Critical Illness: a Cohort Study Standard diagnosis test - Critically Ill, Organ Failure, Multiple | Recruiting | University Medical Center Groningen | 5000 | 2022-01-01 | 2026-05-26 | |
| Evaluation of Corrected Carotid Flow Time Variations During Passive Leg Lift to Predict Response to Filling. passive leg lift test - Organ Failure, Multiple | Completed | Centre Hospitalier de Cornouaille | 21 | 2021-04-01 | 2022-03-09 | |
| Red Cell Rejuvenation for the Attenuation of Transfusion Associated Organ Injury in Cardiac Surgery rejuvesol Solution, Standard Care - Organ Failure, Multiple, Inflammation | Phase 2 | Withdrawn | University of Leicester | 2020-12-01 | 2021-04-29 | |
| DNA Damage in Critically Ill COVID-19 Patients COMET ASSAY - Covid19, Organ Failure, Multiple | Completed | University Hospital Hradec Kralove | 10 | 2020-11-23 | 2022-09-27 | |
| The PRE-OP ENERGY Trial High energy diet - Cardiac Valve Disease, Coronary Artery Disease | Not applicable | Unknown | University of Leicester | 116 | 2019-05-07 | 2023-11-07 |
| Comparing the Prognosis of Lactate-directed and Goal-directed Therapy in Hyperthermic Intraperitoneal Chemotherapy. Lactate-directed therapy, Goal-directed therapy - Organ Failure, Multiple | Not applicable | Withdrawn | Taipei Medical University WanFang Hospital | 2019-05-06 | 2020-06-04 | |
| The Val-CARD Trial Sodium Valproate - Cardiac Valve Disease, Coronary Artery Disease | Phase 1 / Phase 2 | Terminated | University of Leicester | 45 | 2018-11-06 | 2026-08-17 |
| Sepsis in the ICU-II Exposure is septic shock (defined according to Sepsis-III) and standard treatment according to departmental protocols. - Septic Shock, Sepsis | Active not recruiting | Linkoeping University | 379 | 2018-09-17 | 2026-03-17 | |
| Elevated Stearoyl-CoA Desaturase-1 Expression Predicts the Disease Severity of Severe Acute Pancreatitis Acute Pancreatitis, Organ Failure, Multiple | Unknown | Nanjing University School of Medicine | 216 | 2018-01-01 | 2017-11-27 | |
| Clinical Outcome Study of High-dose Meropenem in Sepsis and Septic Shock Patients Meropenem standard dose, Meropenem high dose - Sepsis, Septic Shock | Not applicable | Completed | Mahidol University | 76 | 2017-11-27 | 2019-03-12 |
Showing 20 of 23. Sign in to see all of them.
Multiple Organ Failure (23) · Pancreatitis (4) · Shock, Septic (4) · Critical Illness (3) · Sepsis (3) · Coronary Artery Disease (2) · Heart Valve Diseases (2) · Respiratory Insufficiency (2) · COVID-19 (1) · Cardiomyopathies (1) · Dyspepsia (1) · Gastroparesis (1) · Infections (1) · Inflammation (1) · Intermittent Fasting (1)
Pathologic Processes (23) · Pathological Conditions, Signs and Symptoms (23) · Shock (22) · Digestive System Diseases (5) · Infections (5) · Systemic Inflammatory Response Syndrome (5) · Inflammation (4) · Pancreatic Diseases (4) · Respiratory Tract Diseases (4) · Cardiovascular Diseases (3) · Disease Attributes (3) · Heart Diseases (3) · Arterial Occlusive Diseases (2) · Arteriosclerosis (2) · Coronary Disease (2)
Early Goal-Directed Therapy (1) · Erythrocyte Transfusion (1) · Glutamine (1) · Medicine, Chinese Traditional (1) · Meropenem (1) · Standard of Care (1) · Valproic Acid (1) · salicylhydroxamic acid (1)
University of Leicester (3) · IRCCS Azienda Ospedaliero-Universitaria di Bologna (2) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Boston Children's Hospital (1) · Centre Hospitalier de Cornouaille (1) · China Medical University Hospital (1) · ETH Zurich (1) · Linkoeping University (1) · Liverpool University Hospitals NHS Foundation Trust (1) · Mahidol University (1) · Nanjing University School of Medicine (1) · Peking Union Medical College Hospital (1) · Shanghai Zhongshan Hospital (1) · Taipei Medical University WanFang Hospital (1) · University Hospital Hradec Kralove (1)
France (4) · United Kingdom (4) · Italy (3) · China (2) · Australia (1) · Canada (1) · Czechia (1) · Netherlands (1) · Sweden (1) · Switzerland (1) · Taiwan (1) · Thailand (1) · United States (1)
Baofeng Zhu, MD (1) · Belaid Bouhemad, MD, PhD (1) · Bernard Cholley, MD, PhD (1) · Camille Jeanne-Leroyer, PharmD (1) · Daoyuan Jing, MD (1) · Dong Wu, M.D. (1) · Frederik Keus, PhD (1) · Gavin J Murphy, MD (1) · Gavin J Murphy, Prof (1) · Gavin Murphy, MD (1) · George Papachristou, MD (1) · Giovanni Vitale, MD (1) · Hong Liu, MD (1) · Jianzhong Yang, MD (1)
PMID 25872171, PMID 30135233, PMID 30483997, PMID 30569031, PMID 32161093, PMID 32318268, PMID 32643025, PMID 32877220, PMID 33921159, PMID 33955376, PMID 38236316, PMID 40750277, PMID 40906653
2018 (1)