84 completed, 2 terminated, 2 unknown, 1 not yet recruiting. 89 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 89 | Completed 84, Terminated 2, Unknown 2, Not yet recruiting 1 |
Follow Opportunistic Infections: new trials by email Literature Review of Opportunistic Infections trials Research Report on Opportunistic Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Enhanced Treatment Strategy for Disseminated MAC Infection in HIV Patients: A Randomized Controlled Trial Standard Triple Therapy, Experimental: Standard Triple Therapy Plus Fluoroquinolone - Opportunistic Infections, HIV Related, Disseminated Mycobacterium Avium Complex Infection | Not applicable | Not yet recruiting | Shanghai Public Health Clinical Center | 124 | 2026-04-30 | 2026-05-13 |
| Re-engagement at Discharge 2 Community Health Worker Post-Discharge Intervention - HIV/AIDS, Hospitalization | Not applicable | Completed | University of Maryland, Baltimore | 97 | 2023-08-18 | 2025-08-07 |
| Evaluation of Advanced HIV Disease Differentiated Care Model in Malawi Enhanced package for AHD care - Opportunistic Infections, HIV-Related, Cryptococcal Infections | Not applicable | Completed | Elizabeth Glaser Pediatric AIDS Foundation | 700 | 2021-06-01 | 2026-09-10 |
| Point-of Care Ultrasound for Patients With HIV Opportunistic infection Ultrasound (OpUS) screening - HIV/AIDS, Opportunistic Infections, HIV Related | Not applicable | Completed | Erasmus Medical Center | 34 | 2020-07-01 | 2022-12-20 |
| Driving Reduced AIDS-associated Meningo-encephalitis Mortality DREAMM - AIDS-Related Opportunistic Infections, Meningo-encephalitis | Not applicable | Completed | St George's, University of London | 495 | 2016-04-23 | 2022-05-04 |
| A Study of Co-infections of HIV-1 and Schistosoma Mansoni and Its Impact on Praziquantel Treatment Outcomes Praziquantel and Albendazole - Anemia, Intestinal Helminthiasis | Not applicable | Unknown | Catholic University of Health and Allied Sciences | 2000 | 2012-05-01 | 2012-03-05 |
| Isoniazid Plus Antiretroviral Therapy to Prevent Tuberculosis in HIV-infected Persons isoniazid, Placebo - Tuberculosis, Latent Tuberculosis Infection | Not applicable | Completed | University of Cape Town | 1368 | 2007-11-01 | 2012-07-17 |
| Long-Term Assessment for Metabolic, Cardiovascular and Neurologic Problems in HIV-Infected Patients With Increased CD4 Cells Counts Following Anti-HIV Therapy Azithromycin - Mycobacterium Avium-intracellulare Infection, HIV Infections | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 636 | 1997-10-01 | 2012-10-25 |
| A Double-Blind Placebo-Controlled Group Comparative Study To Evaluate the Safety and Effectiveness of Aerosol Pentamidine in the Prophylaxis of Pneumocystis Carinii Pneumonia in Patients With AIDS Post First Episode PCP Pentamidine isethionate - Pneumonia, Pneumocystis Carinii, HIV Infections | Not applicable | Completed | Fisons | 2005-06-24 | ||
| A Randomized, Double-Blind, Placebo Controlled Study of l-Leucovorin in Combination With Trimethoprim / Sulfamethoxazole in the Therapy of Pneumocystis Carinii Pneumonia in Patients With the Acquired Immunodeficiency Syndrome Trimethoprim, Sulfamethoxazole, Leucovorin calcium - Pneumonia, Pneumocystis Carinii, HIV Infections | Not applicable | Completed | Lederle Laboratories | 2005-06-24 | ||
| Metabolism of Antituberculosis Drugs in HIV-Infected Persons With Tuberculosis Ethambutol hydrochloride, Isoniazid, Pyrazinamide - HIV Infections, Tuberculosis | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 50 | 2011-03-02 | |
| Aerosols in the Treatment of Pneumocystis Pneumonia: A Pilot Study Quantitating the Deposition of Aerosolized Pentamidine as Delivered in ACTG 040 and Comparing Its Toxicity With Parenteral Pentamidine Therapy Pentamidine isethionate - Pneumonia, Pneumocystis Carinii, HIV Infections | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 45 | 2021-11-03 | |
| A 28-Day Study of Diclazuril in the Treatment of Cryptosporidiosis in Patients With AIDS Diclazuril - Cryptosporidiosis, HIV Infections | Not applicable | Completed | Janssen, LP | 2005-06-24 | ||
| A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-Sulfadiazine Atovaquone - Toxoplasmosis, Cerebral, HIV Infections | Not applicable | Completed | Glaxo Wellcome | 2005-06-24 | ||
| An Open Study of Foscarnet Treatment of Acyclovir-Resistant Herpes Simplex Virus in Patients With the Acquired Immunodeficiency Syndrome and Other Immunodeficiencies Foscarnet sodium - Herpes Simplex, HIV Infections | Not applicable | Completed | Astra USA | 2005-06-24 | ||
| A Controlled Trial Comparing the Efficacy of Aerosolized Pentamidine and Parenteral / Oral Trimethoprim - Sulfamethoxazole in the Treatment of Pneumocystis Carinii Pneumonia in AIDS Pentamidine isethionate - Pneumonia, Pneumocystis Carinii, HIV Infections | Not applicable | Completed | LyphoMed | 2005-06-24 | ||
| A Prospective Study of Multidrug Resistance and a Pilot Study of the Safety of and Clinical and Microbiologic Response to Levofloxacin in Combination With Other Antimycobacterial Drugs for Treatment of Multidrug-Resistant Pulmonary Tuberculosis (MDRTB) in HIV-Infected Patients. Cycloserine, Ethionamide, Capreomycin sulfate - HIV Infections, Tuberculosis | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 525 | 2021-11-03 | |
| An Open, Non-Comparative Study of Intravenous and Oral Fluconazole in the Treatment of Acute Cryptococcal Meningitis Fluconazole - Meningitis, Cryptococcal, HIV Infections | Not applicable | Completed | Pfizer | 2005-06-24 | ||
| A Randomized Double Blind Protocol Comparing Amphotericin B With Flucytosine to Amphotericin B Alone Followed by a Comparison of Fluconazole and Itraconazole in the Treatment of Acute Cryptococcal Meningitis Itraconazole, Flucytosine, Fluconazole - Meningitis, Cryptococcal, HIV Infections | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 400 | 2021-11-02 | |
| Aerosols in the Treatment of Asymptomatic Pneumocystis Pneumonia: A Pilot Study Assessing the Effectiveness of Aerosolized Pentamidine as Treatment of Subclinical Pneumocystis Infection in Patients With No Clinical Symptoms Pentamidine isethionate - Pneumonia, Pneumocystis Carinii, HIV Infections | Not applicable | Completed | National Institute of Allergy and Infectious Diseases (NIAID) | 20 | 2021-11-02 |
Showing 20 of 89. Sign in to see all of them.
AIDS-Related Opportunistic Infections (86) · HIV Infections (83) · Acquired Immunodeficiency Syndrome (77) · Pneumonia, Pneumocystis (15) · AIDS-Related Complex (12) · Meningitis (12) · Meningitis, Cryptococcal (12) · Cryptococcosis (11) · Cytomegalovirus Infections (11) · Cytomegalovirus Retinitis (10) · Multiple Acyl Coenzyme A Dehydrogenase Deficiency (10) · Candidiasis, Oral (8) · Mycobacterium avium-intracellulare Infection (7) · Retinitis (7) · Tuberculosis (7)
Blood-Borne Infections (88) · Communicable Diseases (88) · Immune System Diseases (88) · Immunologic Deficiency Syndromes (88) · Infections (88) · Lentivirus Infections (88) · RNA Virus Infections (88) · Retroviridae Infections (88) · Virus Diseases (88) · Genital Diseases (86) · Sexually Transmitted Diseases (86) · Sexually Transmitted Diseases, Viral (86) · Urogenital Diseases (86) · Slow Virus Diseases (80)
Fluconazole (14) · Pentamidine (10) · Ganciclovir (8) · Amphotericin B (7) · Foscarnet (6) · Isoniazid (6) · Zidovudine (6) · Azithromycin (5) · Pyridoxine (5) · Flucytosine (4) · Pyrazinamide (4) · Rifampin (4) · Acyclovir (3) · Clindamycin (3) · Ethambutol (3)
National Institute of Allergy and Infectious Diseases (NIAID) (24) · Pfizer (12) · Hoffmann-La Roche (7) · Astra USA (5) · Fisons (5) · Bristol-Myers Squibb (3) · Glaxo Wellcome (3) · Ionis Pharmaceuticals, Inc. (2) · Jacobus Pharmaceutical (2) · Janssen, LP (2) · LyphoMed (2) · Pharmacia (2) · Abbott (1) · Amgen (1) · Catholic University of Health and Allied Sciences (1)
United States (82) · Canada (7) · Puerto Rico (3) · Malawi (2) · Tanzania (2) · Cameroon (1) · Netherlands (1) · South Africa (1) · Zambia (1)
Gordin F (3) · David Perlman (2) · A. Clinton White (1) · Allen McCutchan (1) · Angela Loyse, MD (1) · Appolinaire Tiam, MBChB, MMed, PhD (1) · Armstrong D (1) · Benson C (1) · Besch CL (1) · Black JR (1) · Brown LS (1) · Cassidy Claassen, MD (1) · Chaisson R (1) · Chirgwin K (1)
PMID 16131307, PMID 19617848, PMID 21293986, PMID 24835842, PMID 37500120, PMID 37802567, PMID 38041058