73 completed, 14 unknown, 8 recruiting, 5 not yet recruiting. 29 Not applicable, 26 Phase 3, 9 Phase 4, 8 Phase 1, 8 Phase 2.
Follow Pneumonia, Pneumocystis: new trials by email Literature Review of Pneumonia, Pneumocystis trials Research Report on Pneumonia, Pneumocystis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Low- vs Standard-Dose TMP-SMX for Prevention of Pneumocystis Pneumonia After Kidney Transplantation Trimethoprim-Sulfamethoxazole (TMP-SMX) - Pneumocystis Jirovecii Pneumonia, Kidney Transplantation | Phase 4 | Not yet recruiting | Anhui Provincial Hospital | 1084 | 2026-06-01 | 2026-06-01 |
| Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives) Clindamycin + primaquine, Pentamidine, Atovaquone - Pneumocystis, Pneumocystis Infection | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2026-03-01 | 2026-01-21 |
| How Long Should we Give Steroids for Patients With Severe PCP Systemic corticosteroids - Pneumocystis Pneumonia, Pneumocystis | Phase 4 | Not yet recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 416 | 2026-01-30 | 2026-01-09 |
| CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia Caspofungin Acetate 50 MG, Physiologic saline - Pneumocystis Pneumonia, Pneumocystis Jirovecii Infection | Phase 1 / Phase 2 | Recruiting | University Hospital, Tours | 100 | 2025-12-02 | 2026-10-09 |
| Low Dose Trimethoprim-Sulfamethoxazole for the Treatment of Pneumocystis Jirovecii Pneumonia trimethoprim-sulfamethoxazole - Pneumocystis, Pneumocystis Pneumonia | Phase 3 | Recruiting | Todd C. Lee MD MPH FIDSA | 416 | 2025-11-28 | 2026-02-20 |
| Derivation and Validation of the Fungal Pneumonia Assessment and Likelihood Predictor Score FUNGAL-P Score Assessment - Pneumonia, Fungal Pneumonia | Recruiting | Azienda Ospedaliero-Universitaria Careggi | 400 | 2025-11-13 | 2026-07-02 | |
| Corticosteroids for PJP in Non-HIV Immunocompromised Adults Saline (0.9%, sterile, for infusion), Low Dose Corticosteroids, Moderate dose corticosteroids - Pneumocystis Jiroveci Pneumonia | Phase 3 | Not yet recruiting | Qingyuan Zhan | 240 | 2025-09-08 | 2025-09-09 |
| Pneumocystis Jirovecii Genotyping Pneumocystis Pneumonia | Not yet recruiting | Nottingham University Hospitals NHS Trust | 70 | 2025-09-01 | 2025-06-27 | |
| Optimizing the Diagnosis of Pneumocystis in Immunocompromised Patients Biological sampling - Pneumocystis, Immunocompromised Patients | Recruiting | Assistance Publique - Hôpitaux de Paris | 240 | 2025-07-08 | 2026-04-23 | |
| Performance Evaluation of the Fujifilm Wako Beta-D-glucan Technique in the Diagnosis of Major Invasive Fungal Infections (IFI) Beta-1,3/1,6-D-Glucan - Candidemia, Aspergillosis Invasive | Completed | Central Hospital, Nancy, France | 280 | 2024-12-17 | 2025-12-09 | |
| Efficacy and Safety of Prophylactic Treatment for Pneumocystis Jirovecii Pneumonia in Patients With Autoimmune Inflammatory Rheumatic Disease Trimethoprim/Sulfamethoxazole - Pneumonia, Pneumocystis, Autoimmune Inflammatory Rheumatic Disease | Phase 4 | Recruiting | Tongji Hospital | 800 | 2024-07-20 | 2024-10-01 |
| Droplet Digital PCR and PCR-free BIOSensors for the Detection of Resistance-associated SNPs in Pneumocystis Jirovecii Pneumocystis Pneumonia | Active not recruiting | University Hospital, Brest | 300 | 2024-06-01 | 2024-08-09 | |
| Rezafungin for Treatment of Pneumocystis Pneumonia in HIV Adults Co-Trimoxazole, Rezafungin Acetate / Co Trimoxazole - Pneumocystis Pneumonia | Phase 2 | Recruiting | Mundipharma Research Limited | 50 | 2023-11-14 | 2025-04-03 |
| Introduction of Polymerase Chain Reaction (PCR) in Microbiology and Parasitology Malaria, Pneumocystis, Leishmania | Recruiting | Fondazione IRCCS Policlinico San Matteo di Pavia | 200 | 2023-09-01 | 2025-12-08 | |
| Caspofungin for Pneumocystis Pneumonia in PLWHIV. HIV-1-infection, Pneumocystis Pneumonia | Recruiting | Instituto Nacional de Enfermedades Respiratorias | 60 | 2023-08-01 | 2024-11-19 | |
| Prospective Observational Study on the Incidence of Opportunistic Fungal Infections Pneumocystis Jirovecii Infection, Pneumocystis | Completed | University of Colorado, Denver | 12032 | 2023-07-05 | 2025-04-02 | |
| Radiomics Model for the Diagnosis of Pneumocystis Jirovecii Pneumonia in Non-HIV Patients Radiomic model - Pneumocystis Jirovecii Pneumonia | Unknown | Chinese PLA General Hospital | 140 | 2023-01-15 | 2023-01-27 | |
| Factors Associated With Survival in Patients Having Pneumocystis Jirovecii Pneumocystis Jirovecii Infection | Unknown | University Hospital, Strasbourg, France | 300 | 2023-01-01 | 2023-12-15 | |
| PCP in Immunocompromised Population in Southern China PCR was used to detect pneumocystis in respiratory specimens - Immunocompromised Patients, Pneumocystis Pneumonia | Unknown | First Affiliated Hospital of Guangxi Medical University | 300 | 2021-05-12 | 2022-11-04 | |
| Comprehensive Diagnosis and Treatment Strategy for Opportunistic Fungal Infections in AIDS Patients examination methods - Opportunistic Fungal Infections | Unknown | Guangzhou 8th People's Hospital | 600 | 2021-04-01 | 2021-12-13 |
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HIV Infections (59) · Acquired Immunodeficiency Syndrome (55) · AIDS-Related Opportunistic Infections (30) · AIDS-Related Complex (16) · Pneumonia (10) · Pneumocystis Infections (8) · Respiratory Aspiration (7) · Infections (5) · Mycoses (4) · COVID-19 (3) · Invasive Pulmonary Aspergillosis (3) · Aspergillosis (2) · Candidemia (2) · Candidiasis (2)
Bacterial Infections and Mycoses (107) · Respiratory Tract Diseases (107) · Lung Diseases (106) · Lung Diseases, Fungal (106) · Respiratory Tract Infections (106) · Mycoses (103) · Infections (102) · Pneumocystis Infections (99) · Pneumonia (97) · RNA Virus Infections (65) · Virus Diseases (65) · Immune System Diseases (64) · Blood-Borne Infections (62) · Communicable Diseases (62) · Genital Diseases (62)
Trimethoprim, Sulfamethoxazole Drug Combination (23) · Pentamidine (22) · Leucovorin (13) · trimetrexate glucuronate (12) · Atovaquone (10) · Dapsone (10) · Zidovudine (7) · Methylprednisolone (5) · Trimethoprim (5) · Clindamycin (4) · Primaquine (4) · Sulfamethoxazole (4) · Adrenal Cortex Hormones (3) · Caspofungin (3) · 8-aminoquinoline (2)
National Institute of Allergy and Infectious Diseases (NIAID) (36) · Fisons (5) · U.S. Bioscience (5) · Glaxo Wellcome (4) · Assistance Publique - Hôpitaux de Paris (2) · Central Hospital, Nancy, France (2) · Jacobus Pharmaceutical (2) · LyphoMed (2) · McGill University Health Centre/Research Institute of the McGill University Health Centre (2) · Mundipharma Research Limited (2) · Peking Union Medical College Hospital (2) · Rennes University Hospital (2) · Shanghai Public Health Clinical Center (2) · University of Pittsburgh (2) · Abbott (1)
United States (62) · France (15) · China (11) · Puerto Rico (7) · Belgium (4) · Canada (4) · Tanzania (4) · Germany (3) · Italy (3) · Mexico (2) · South Africa (2) · United Kingdom (2) · Botswana (1) · Brazil (1) · Denmark (1)
Feinberg J (5) · Alison Morris-Gimbel, MD (2) · B Montgomery (2) · Black JR (2) · El-Sadr W (2) · Emily G McDonald, MD MSc (2) · Fischl M (2) · Frame P (2) · Luskin-Hawk R (2) · Masur H (2) · Ptachcinski R (2) · Sattler FR (2)
PMID 41151592, PMID 15504856, PMID 16304338, PMID 18046534, PMID 18230259, PMID 20607114, PMID 20946413, PMID 21732834, PMID 22548840, PMID 23940606, PMID 25603113, PMID 26872154, PMID 26935726, PMID 29313714, PMID 29514207, PMID 30776290, PMID 31548210, PMID 31633150, PMID 32194238, PMID 32391667, PMID 32479781, PMID 32653726, PMID 32671131, PMID 33005696, PMID 33213011, PMID 33438477, PMID 33538349, PMID 33586013, PMID 34349985, PMID 34682270, PMID 34682277, PMID 34843666, PMID 34988242, PMID 35602475, PMID 35657109, PMID 35863836, PMID 36803640, PMID 37541984, PMID 37656874, PMID 37773627, PMID 38167022, PMID 38235979, PMID 40652952, PMID 42558999, PMID 9872631
2016 (1), 2017 (1), 2023 (1), R01HL083461 (1), R01HL090339 (1), U01AI068632 (1)