44 completed, 12 unknown, 8 terminated, 4 recruiting. 19 Phase 3, 17 Phase 2, 15 Not applicable, 11 Phase 4, 8 Phase 1.
Follow Amphotericin B: new trials by email Literature Review of Amphotericin B trials Research Report on Amphotericin B
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Safety and Efficacy of Liposomal Amphotericin B for Patients With Invasive Mold Diseases in Liver Transplant Recipients AmBisome (Amphotericin B) Liposome - Invasive Mold Diseases | Not applicable | Not yet recruiting | Beijing Friendship Hospital | 60 | 2026-08-08 | 2026-07-24 |
| Amphotericin B for Breakthrough Fungal Infections After Triazole Prophylaxis in Hematological Patients Amphotericin B - Invasive Fungal Disease | Not applicable | Not yet recruiting | Peking University People's Hospital | 15 | 2026-04-01 | 2026-04-30 |
| Low-Dose Liposomal Amphotericin B for Invasive Fungal Infection Prophylaxis in Neutropenic Children Liposomal Amphotericin B (LAmB) - Thalassemia, Hematopoietic Stem Cell Transplantation | Recruiting | Haikou Affiliated Hospital of Central South University Xiangya School of Medicine | 30 | 2026-02-01 | 2026-07-24 | |
| Impact Of The Gut Microbiota On Host Cells Energy Metabolism in Health And In Inflammatory Bowel Disease Vancomycin /Amphotericin B (Fungizone®) /Gentamicine 80 mg, Inulin/Inulin C13 - IBD, Crohn Disease | Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 45 | 2026-01-02 | 2026-03-12 |
| Low-dose Liposomal Amphotericin B for Antifungal Prophylaxis in Prolonged Neutropenia Patients Liposomal Amphotericin B - Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia | Recruiting | Haikou Affiliated Hospital of Central South University Xiangya School of Medicine | 30 | 2025-08-01 | 2026-08-13 | |
| Amphotericin B Versus Isavuconazole for Mucormycosis: A Comparative Efficacy and Safety Study Amphotericin B, Isavuconazole - Mucormycosis | Active not recruiting | Qiu Ye | 150 | 2025-05-15 | 2025-09-25 | |
| Human Bioequivalence Study of Amphotericin B Liposome for Injection Amphotericin B Liposome for Injection (strength: 50 mg, Sichuan Huiyu Pharmaceutical Co., Ltd.), Amphotericin B Liposome for Injection (trade name: Ambisome®, strength: 50 mg, MAH: Gilead Sciences) - Invasive Fungal Infections, Neutropenic Fever | Not applicable | Completed | Sichuan Huiyu Pharmaceutical Co., Ltd | 42 | 2025-05-13 | 2026-05-22 |
| Single High-dose of Liposomal Amphotericin B in Combination With B/F/TAF for HIV/AIDS-associated Talaromycosis Amphotericin B, AmBisome - HIV/AIDS-associated Talaromycosis | Not applicable | Not yet recruiting | Shanghai Public Health Clinical Center | 116 | 2025-05-01 | 2025-04-13 |
| Urogenital Infections in Women of Reproductive Age and the Activity of 4-Thiazolidinone Derivatives Against Pathogens Microbiological identification kits (ANAEROtest, STAPHYtest, ENTEROtest, NEFERMtest), Antibiotic therapy after the results of antibiotic sensitivity test (Mostly Oxacillin, Benzylpenicillin, Ceftriaxone, Doxycycline, Clindamycin), Suppositoria for vaginal microflora recovery (Giynoflor) - Bacterial Vaginosis | Phase 1 | Active not recruiting | Danylo Halytsky Lviv National Medical University | 200 | 2023-09-01 | 2024-09-27 |
| Amphotericin B for Non-HIV Cryptococcal Meningitis Patients Amphotericin B 0.5 mg/kg/day i.v. combined with flucytosine four times per day orally for the first 4 weeks., Amphotericin B 0.7 mg/kg/day i.v. combined with flucytosine four times per day orally for the first 4 weeks. - Cryptococcal Meningitis, Antifungal Agents | Phase 4 | Unknown | Huashan Hospital | 250 | 2023-08-13 | 2023-12-21 |
| Bioequivalence of Amphotericin B Liposome for Injection Amphotericin B liposome for injection, AmBisome - Bioequivalence | Phase 1 | Completed | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 32 | 2023-06-02 | 2023-09-28 |
| A Study of ABCD for Injection in Subjects With Invasive Candidiasis and Invasive Aspergillus Amphotericin B cholesteryl Sulfate Complex for Injection - Invasive Candidiasis, Invasive Aspergillosis | Phase 3 | Completed | CSPC Ouyi Pharmaceutical Co., Ltd. | 31 | 2023-03-30 | 2025-04-09 |
| Encochleated Oral Amphotericin for Cryptococcal Meningitis Trial 3 MAT2203, Amphotericin B - Cryptococcal Meningitis | Phase 3 | Unknown | Matinas BioPharma Nanotechnologies, Inc. | 270 | 2023-01-01 | 2022-09-15 |
| Micafungin Versus Amphotercine B in Treatment of Invasive Fungal Infection Micafungin, Amphotericin B - Neonatal Infection, Invasive Fungal Infections | Phase 4 | Completed | Ain Shams University | 56 | 2022-10-20 | 2024-05-16 |
| Clinical Study of ABCD in the Treatment of Cryptococcal Meningitis Amphotericin B Colloidal Dispersion, flucytosine, fluconazole - Cryptococcal Meningitis | Not applicable | Unknown | Peking Union Medical College Hospital | 30 | 2022-08-22 | 2022-07-22 |
| A Study of Amphotericin B Liposome for Injection in Patients With Persistent Neutropenia and Fever Amphotericin B liposomes - Neutropenia and Fever | Phase 3 | Unknown | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 93 | 2021-12-15 | 2021-11-05 |
| Clinical Effectiveness and Safety of Amphotericin B With Flucytosine-Fluconazole Therapy for Cryptococcal Meningitis Amphotericin B 1 mg/kg 1 week & Flucytosine 100 mg/kg 1 week followed by Fluconazole 1200 mg/day 1 week - Cryptococcal Meningitis | Completed | University of Pharmacy, Yangon | 30 | 2020-10-01 | 2022-04-21 | |
| A Pilot Bioequivalence Study Between Amphotericin B Liposome for Injection and AmBisome® in Healthy Subjects Amphotericin B liposome for injection, AmBisome® - Bioequivalence | Phase 1 | Completed | CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. | 12 | 2020-06-04 | 2021-08-06 |
| AmB Dose for Cryptococcal Meningitis Amphotericin B, Flucytosine - Cryptococcal Meningitis, HIV Infections | Phase 3 | Unknown | Shanghai Public Health Clinical Center | 40 | 2020-01-02 | 2019-10-29 |
| Amphotericin B Cholesteryl Sulfate Complex for Injection(ABCD) in the Treatment of Invasive Candidiasis and Invasive Aspergillosis Amphotericin B cholesteryl sulfate complex for injection(ABCD) - Invasive Candidiasis, Invasive Aspergillosis | Phase 2 | Unknown | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 60 | 2020-01-01 | 2020-01-13 |
Showing 20 of 74. Sign in to see all of them.
Meningitis, Cryptococcal (23) · HIV Infections (19) · Acquired Immunodeficiency Syndrome (15) · Meningitis (12) · AIDS-Related Opportunistic Infections (10) · Cryptococcosis (10) · Invasive Fungal Infections (7) · Leishmaniasis, Visceral (6) · Mycoses (6) · Neutropenia (5) · Aspergillosis (4) · Candidiasis (3) · Invasive Pulmonary Aspergillosis (3) · AIDS-Related Complex (2) · Blastomycosis (2)
National Institute of Allergy and Infectious Diseases (NIAID) (7) · Pfizer (6) · Matinas BioPharma Nanotechnologies, Inc. (3) · University of Pittsburgh (3) · Assistance Publique - Hôpitaux de Paris (2) · CSPC ZhongQi Pharmaceutical Technology Co., Ltd. (2) · CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. (2) · Haikou Affiliated Hospital of Central South University Xiangya School of Medicine (2) · Shanghai Public Health Clinical Center (2) · TTY Biopharm (2) · University of Brasilia (2) · Ain Shams University (1) · Alkermes, Inc. (1) · All India Institute of Medical Sciences (1) · Astellas Pharma Europe B.V. (1)
United States (29) · China (15) · Canada (5) · India (5) · Brazil (4) · Thailand (3) · Uganda (3) · France (2) · Israel (2) · Peru (2) · Puerto Rico (2) · South Africa (2) · Spain (2) · Taiwan (2) · Ukraine (2)
Armstrong D (2) · Shahid Husain, MD (2) · Alexandra Freeman, MD (1) · Amir Horev, MD (1) · Ana LT Rabello, MD PhD (1) · Andrea L de Carvalho, MD (1) · Ban H Tan, Dr (1) · Baodong Ye (1) · Bill McGhee, PharmD (1) · Carlos HN Costa, MD PhD (1) · Charussri Leeyaphan, MD (1) · Danny Benjamin, MD (1) · David B Meya, MBChB (1) · David R Boulware, MD (1)
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