4 not yet recruiting, 4 recruiting, 1 completed, 1 enrolling by invitation. 11 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 11 | Not yet recruiting 4, Recruiting 4, Completed 1, Enrolling by invitation 1, Unknown 1 |
Follow Opioid: new trials by email Literature Review of Opioid trials Research Report on Opioid
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| MedSMA℞T Mobile ED MedSMA℞T Mobile - Opiate-Related Disorders, Opiate Use Disorder | Not applicable | Not yet recruiting | Olufunmilola Abraham | 244 | 2027-08-01 | 2026-10-09 |
| Fentanyl Versus Opioid Free Multimodal Analgesia for Perioperative Pain Control in Children With Mild to Moderate Obstructive Sleep Apnea Group A: Fentanyl-Based Analgesia, Group B: Opioid-Free Multimodal Analgesia - Adenotonsillectomy, Obstructive Sleep Apnea (OSA) | Not applicable | Not yet recruiting | Ain Shams University | 64 | 2026-11-30 | 2026-02-27 |
| How Does the Opioid System Shape Stress and Social Behaviour in Men and Women and What Role Does Childhood Unpredictability Play? Morphine, Placebo - Stress, Early Life Stress | Not applicable | Recruiting | Sara L. Kroll | 72 | 2026-09-24 | 2026-09-28 |
| Impact Evaluation of the Therapeutic Initiative's Prescribing Portrait and Therapeutics Letter on Opioid Use by Dentists Regular intervention, Enhanced intervention - Clinical Audit, Quality Improvement | Not applicable | Not yet recruiting | University of British Columbia | 3498 | 2026-01-06 | 2026-01-08 |
| Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients Discharge pain medication prescription - Orthopaedic Related Pain (Musculoskeletal Pain), Opioid | Not applicable | Recruiting | Massachusetts General Hospital | 100 | 2025-10-06 | 2026-06-25 |
| The Effect of Opioid Free Anesthesia Using Ultrasound-Guided Bilateral Transversus Abdominus Plane Block and Dexmedetomidine Infusion Opioid Free Anesthesia, Control group (general anesthesia) - Anesthesia, Opioid | Not applicable | Not yet recruiting | Tanta University | 150 | 2025-08-30 | 2025-08-11 |
| Evaluation of Virtual Reality for Reducing Opioid Use After Cardiac and Thoracic Surgery Interactive Virtual Reality, Passive Virtual Reality - Heart Surgery, Thoracic Surgery | Not applicable | Recruiting | Filomena R B G Galas | 60 | 2024-12-10 | 2026-04-15 |
| Bilateral Erector Spinae Plane Block as an Opioid Sparing Technique for Selective Dorsal Rhizotomy in Pediatric Patients With Spastic Cerebral Palsy Erector Spinae Plane Block - Erector Spinae Plane Block, Opioid | Not applicable | Completed | Tanta University | 30 | 2024-09-17 | 2025-11-21 |
| Acute Preoperative Pain and Chronic Post-surgical Pain in Emergency Surgery questionnaire, phone call - Chronic Postsurgical Pain, Acute Pain | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 693 | 2024-08-29 | 2026-01-16 |
| Role of High Frequency RTMS in Management of Opioid Use Disorder rTMS, Psychotherapy - Addiction, Opioid | Not applicable | Enrolling by invitation | Assiut University | 40 | 2024-08-22 | 2024-11-14 |
| Comparison of Opioid Consumption During TCI Guided by NOL Index or Standard Care Undergoing Intracranial Tumor Surgery Nociception Leve Indeks - Target Controlled Infusion, Intracranial Neoplasm | Not applicable | Unknown | Turkish Society of Anesthesiology and Reanimation | 50 | 2020-09-02 | 2023-06-22 |
Opioid-Related Disorders (2) · Pain (2) · Acute Pain (1) · Behavior, Addictive (1) · Brain Neoplasms (1) · Cerebral Palsy (1) · Musculoskeletal Pain (1) · Nociceptive Pain (1) · Pain, Postoperative (1) · Sleep Apnea, Obstructive (1) · Social Behavior (1) · Stress, Psychological (1)
Neurologic Manifestations (4) · Pathological Conditions, Signs and Symptoms (4) · Signs and Symptoms (4) · Nervous System Diseases (3) · Behavior (2) · Brain Diseases (2) · Central Nervous System Diseases (2) · Chemically-Induced Disorders (2) · Mental Disorders (2) · Narcotic-Related Disorders (2) · Pain (2) · Substance-Related Disorders (2) · Apnea (1) · Behavioral Symptoms (1) · Brain Damage, Chronic (1)
Anesthesia, General (1) · Control Groups (1) · Morphine (1) · Psychotherapy (1) · Surveys and Questionnaires (1)
Tanta University (2) · Ain Shams University (1) · Assiut University (1) · Centre Hospitalier Universitaire, Amiens (1) · Filomena R B G Galas (1) · Massachusetts General Hospital (1) · Olufunmilola Abraham (1) · Sara L. Kroll (1) · Turkish Society of Anesthesiology and Reanimation (1) · University of British Columbia (1)
Egypt (4) · United States (2) · Brazil (1) · Canada (1) · France (1) · Switzerland (1) · Turkey (Türkiye) (1)
Arun Aneja, MD PhD (1) · Colin Dormuth, ScD (1) · Hulya Bilgin (1) · Merihan Ahmed, Resident (1) · Olufunmilola Abraham, PhD (1) · Sara L Kroll, Dr. (1)
PMID 22647429, PMID 23835792, PMID 26154185, PMID 27171828, PMID 30829658, PMID 30997633, PMID 32950246, PMID 33228979, PMID 34597955, PMID 35472586, PMID 35925157, PMID 36091708, PMID 37355243, PMID 37556082