8 completed, 6 recruiting, 4 not yet recruiting, 1 active not recruiting. 7 Not applicable, 5 Phase 4, 3 Phase 3, 2 Phase 2.
Follow Older Patients: new trials by email Literature Review of Older Patients trials Research Report on Older Patients
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Dexmedetomidine-esketamine Combination and Postoperative Cognitive Recovery in Older Patients Intranasal dexmedetomidine-esketamine combination, Intranasal placebo (0.9% saline) - Older Patients, Noncardiac Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 732 | 2026-11-01 | 2026-11-04 |
| Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After Surgery Dex-Esk, Placebo, Active tDCS - Older Patients, Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 1996 | 2026-10-01 | 2026-10-13 |
| Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After Surgery Dex-Esk, Placebo, Active tDCS - Older Patients, Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 1996 | 2026-10-01 | 2026-10-13 |
| Sedation With Dexmedetomidine-esketamine Combination and Delirium in ICU Patients Dexmedetomidine, Dexmedetomidine-esketamine combination - Older Patients, Postoperative Care | Phase 4 | Completed | Peking University First Hospital | 100 | 2025-10-21 | 2026-06-30 |
| Repetitive Transcranial Magnetic Stimulation and Postoperative Neurocognitive Recovery Repetitive transcranial magnetic stimulation, Sham stimulation - Older Patients, Cognitive Impairment | Not applicable | Recruiting | Peking University First Hospital | 568 | 2025-07-28 | 2025-07-31 |
| VEN+DAC+Bu2Flu4 vs Bu2Flu5 Conditioning Regimen for Elderly Myeloid Malignancies Undergoing Allo-HSCT Venetoclax (VEN), Decitabine (DAC), Busulfan (Bu) - Older Patients, Myeloid Malignancies | Phase 2 / Phase 3 | Not yet recruiting | Nanfang Hospital, Southern Medical University | 160 | 2025-07-15 | 2025-07-04 |
| Blood Flow Restriction in Older Adults Blood flow restriction training - Older Patients | Not applicable | Active not recruiting | Universidad Católica San Antonio de Murcia | 18 | 2025-03-12 | 2025-04-04 |
| Evaluation of Prioritized Assessment for Older Patients Living With Frailty Presenting to the Emergency Department Prioritized assessment for older patients living with frailty - Frailty, Length of Stay | Completed | University Hospital, Linkoeping | 1217 | 2025-01-27 | 2025-08-26 | |
| Dexmedetomidine-esketamine Combined Nasal Administration and Emergence Delirium Dexmedetomidine, Esketamine, Normal saline - Older Patients, Nasal Administration | Phase 4 | Completed | Peking University First Hospital | 340 | 2024-09-02 | 2025-07-31 |
| DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%) - Older Patients, Colorectal Cancer | Phase 3 | Recruiting | Leiden University Medical Center | 587 | 2024-07-01 | 2024-10-16 |
| Medical Treatment With or Without Transcatheter Patent Foramen Ovale Closure Transcatheter PFO closure, Optimal medical treatment - Patent Foramen Ovale, Cryptogenic Stroke | Not applicable | Recruiting | Josep Rodes-Cabau | 714 | 2024-06-18 | 2026-03-27 |
| Implementing Geriatric Assessment for Dose Optimization of Cyclin-dependent Kinase (CDK) 4/6-inhibitors in Older Breast Cancer Patients CDK 4/6 inhibitors, Endocrine therapy - Metastatic Breast Cancer, Advanced Breast Cancer | Phase 3 | Recruiting | Region Örebro County | 495 | 2024-04-01 | 2024-11-19 |
| LDL Cholesterol TARGETs in OLDer Patients (Age≥75 Years) With ASCVD (TARGET OLD) Achieving a Target LDL-C level of 25mg/dL≤ LDL-C<70mg/dL, Achieving a Target LDL-C level of 70mg/dL≤ LDL-C<100mg/dL - Atherosclerotic Cardiovascular Disease, Older Patients | Not applicable | Recruiting | China National Center for Cardiovascular Diseases | 4200 | 2023-03-24 | 2023-04-10 |
| Buccal Acupuncture for Delirium Treatment in Older Patients Recovering From Orthopedic Surgery Buccal acupuncture in addition to routine care, Routine care - Older Patients, Orthopedic Surgery | Not applicable | Withdrawn | Peking University First Hospital | 2022-10-01 | 2025-07-31 | |
| Venetoclax Combining With Fludarabine and Melphalan as Conditioning Regimen for Allo-HSCT venetoclax combining with fludarabine and melphalan - Hematologic Malignancy, Older Patients | Phase 2 | Unknown | First Affiliated Hospital of Zhejiang University | 50 | 2021-10-07 | 2021-10-27 |
| ICCI for Older Patients in A&E ICCI - Older Patients | Completed | Bournemouth University | 9 | 2019-09-09 | 2023-07-06 | |
| Prospective Observational Study Based on a Cohort of Geriatric Patients With Hip Fracture Treated in the Centers Belonging to the GIOG Group Hip Fractures, Older Patients | Recruiting | University of Milano Bicocca | 7000 | 2019-07-15 | 2025-07-25 | |
| Improved Function and Quality of Life for Older Patients Receiving Radiotherapy, Part II Geriatric assessment with management - Cancer, Radiotherapy | Not applicable | Completed | Sykehuset Innlandet HF | 178 | 2019-05-08 | 2022-11-09 |
| Telephone Contact Between Hospital and General Practitioner About Medication Review for Older Patients Medication review - Older Patients, Medication Review | Not applicable | Completed | Odense University Hospital | 232 | 2017-11-24 | 2019-03-19 |
| Delirium in Geriatric Hospital Single-bed and Multibed Rooms Delirium, Older Patients | Completed | Aarhus University Hospital | 1014 | 2016-09-15 | 2018-07-06 |
Showing 20 of 21. Sign in to see all of them.
Delirium (2) · Emergence Delirium (2) · Frailty (2) · Atherosclerosis (1) · Breast Neoplasms (1) · Cognitive Dysfunction (1) · Colorectal Neoplasms (1) · Emergencies (1) · Foramen Ovale, Patent (1) · Hematologic Neoplasms (1) · Hip Fractures (1) · Ischemic Stroke (1) · Neoplasm Metastasis (1) · Neoplasms (1) · Stroke (1)
Pathological Conditions, Signs and Symptoms (7) · Mental Disorders (5) · Nervous System Diseases (5) · Neurocognitive Disorders (5) · Pathologic Processes (5) · Confusion (4) · Neurobehavioral Manifestations (4) · Neurologic Manifestations (4) · Signs and Symptoms (4) · Neoplasms (3) · Neoplasms by Site (3) · Cardiovascular Diseases (2) · Delirium (2) · Postoperative Complications (2) · Vascular Diseases (2)
Saline Solution (3) · Dexmedetomidine (2) · fludarabine (2) · Blood Flow Restriction Therapy (1) · Busulfan (1) · Decitabine (1) · Esketamine (1) · Geriatric Assessment (1) · Influenza Vaccines (1) · Medication Review (1) · Melphalan (1) · Sodium Chloride (1) · Therapeutics (1) · Transcranial Magnetic Stimulation (1) · venetoclax (1)
Peking University First Hospital (7) · Aarhus University Hospital (1) · Bournemouth University (1) · Charite University, Berlin, Germany (1) · China National Center for Cardiovascular Diseases (1) · First Affiliated Hospital of Zhejiang University (1) · Josep Rodes-Cabau (1) · Leiden University Medical Center (1) · Nanfang Hospital, Southern Medical University (1) · Odense University Hospital (1) · Region Örebro County (1) · Sykehuset Innlandet HF (1) · Universidad Católica San Antonio de Murcia (1) · University Hospital, Linkoeping (1) · University of Milano Bicocca (1)
China (8) · Denmark (2) · Italy (2) · Norway (2) · Spain (2) · Sweden (2) · Canada (1) · Finland (1) · Germany (1) · Greece (1) · Netherlands (1) · United Kingdom (1)
Dong-Xin Wang, MD, PhD (7) · Antonios Valachis, Assoc Prof (1) · Claudia Spies, MD, Prof. (1) · Else Marie Damsgaard, Professor (1) · Hao-Yu Wang, MD, PhD (1) · Johanneke Portielje, Professor (1) · Joosje Baltussen, MD (1) · Kefei Dou, MD, PhD (1) · Qifa Liu (1) · Yi Luo, M.D. (1)
PMID 25226117, PMID 38853251, PMID 39053972, PMID 39142680, PMID 39253302, PMID 39431459, PMID 40223637, PMID 41645916, PMID 42159161, PMID 42721749
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