3 not yet recruiting, 2 completed. 5 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 5 | Not yet recruiting 3, Completed 2 |
Follow Older Patients: new trials by email Literature Review of Older Patients trials Research Report on Older Patients
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Intranasal Dexmedetomidine-esketamine Combination and Postoperative Cognitive Recovery in Older Patients Intranasal dexmedetomidine-esketamine combination, Intranasal placebo (0.9% saline) - Older Patients, Noncardiac Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 732 | 2026-11-01 | 2026-11-04 |
| Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After Surgery Dex-Esk, Placebo, Active tDCS - Older Patients, Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 1996 | 2026-10-01 | 2026-10-13 |
| Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After Surgery Dex-Esk, Placebo, Active tDCS - Older Patients, Surgery | Phase 4 | Not yet recruiting | Peking University First Hospital | 1996 | 2026-10-01 | 2026-10-13 |
| Sedation With Dexmedetomidine-esketamine Combination and Delirium in ICU Patients Dexmedetomidine, Dexmedetomidine-esketamine combination - Older Patients, Postoperative Care | Phase 4 | Completed | Peking University First Hospital | 100 | 2025-10-21 | 2026-06-30 |
| Dexmedetomidine-esketamine Combined Nasal Administration and Emergence Delirium Dexmedetomidine, Esketamine, Normal saline - Older Patients, Nasal Administration | Phase 4 | Completed | Peking University First Hospital | 340 | 2024-09-02 | 2025-07-31 |
Delirium (1) · Emergence Delirium (1)
Confusion (2) · Mental Disorders (2) · Nervous System Diseases (2) · Neurobehavioral Manifestations (2) · Neurocognitive Disorders (2) · Neurologic Manifestations (2) · Pathological Conditions, Signs and Symptoms (2) · Signs and Symptoms (2) · Delirium (1) · Pathologic Processes (1) · Postoperative Complications (1)
Saline Solution (3) · Dexmedetomidine (2) · Esketamine (1) · Sodium Chloride (1)
Peking University First Hospital (5)
China (5)