17 completed, 3 recruiting, 3 unknown, 2 terminated. 9 Phase 3, 5 Phase 2, 4 Not applicable, 4 Phase 4, 3 Phase 1.
Follow Ocular Inflammation: new trials by email Literature Review of Ocular Inflammation trials Research Report on Ocular Inflammation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study of Ear Nerve Stimulation to Treat Eye Inflammation Cymbathera One System - Ocular Inflammation, Crystalline Lens; Chalcosis | Phase 1 | Recruiting | Memorial Sloan Kettering Cancer Center | 20 | 2026-09-09 | 2026-09-21 |
| Comparison of Topical Treatment for Inflammatory Secretions of the Conjonctiva (Patients With Ocular Prostheses) Hydrocortisone, Dexamethasone, Povidone - Ocular Inflammation, Ocular Prostheses | Phase 3 | Recruiting | Agnes | 30 | 2023-05-12 | 2025-08-15 |
| Safety and Effectiveness of Drop-free Small Incision Cataract Surgery Intraoperative delivery of medication, Kenalog (Triamcinolone), Topical post-operative eyedrops, Prednisolone acetate - Cataract, Ocular Inflammation | Not applicable | Unknown | Visualiza | 100 | 2022-10-01 | 2022-08-09 |
| Safety, Tolerability, Plug Retention and Preliminary Efficacy of Tacrolimus-loaded Punctal Plug in Patients With Moderate to Severe Dry Eye Disease - Cohort B punctum plug insertion, Eye Drops, Lubricant - Dry Eye, Keratoconjunctivitis Sicca | Phase 1 | Unknown | Eximore Ltd. | 20 | 2022-09-29 | 2023-09-07 |
| Tolerability Comparison of Flarex to Lotemax SM Fluorometholone Acetate Ophthalmic Suspension 0.1%, Loteprednol Etabonate Ophthalmic Gel 0.38% - Ocular Inflammation, Keratoconjunctivitis | Phase 4 | Completed | Harrow Inc | 40 | 2021-05-01 | 2026-09-22 |
| Cyclosporine 0.1% Eye Drops as Prophylactic Treatment In Cataract Surgery CycloSPORINE Ophthalmic 0.1% Ophthalmic Emulsion, cationorm eye drops - Ocular Surface Disease, Ocular Inflammation | Early Phase 1 | Completed | Campus Bio-Medico University | 101 | 2021-02-17 | 2023-02-14 |
| Biomarkers in Ocular Inflammation and Uveitis Uveitis, Ocular Inflammation | Completed | National Eye Institute (NEI) | 69 | 2020-12-29 | 2024-09-19 | |
| Dextenza in the Post-op Management of Vitreoretinal Surgeries Dexamethasone Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp - Vitreoretinal Surgery, Ocular Inflammation | Phase 4 | Recruiting | The Cleveland Clinic | 30 | 2020-06-01 | 2026-07-29 |
| Prevalence of SARS-CoV-2 in Conjunctival Swab Samples Among Patients With Conjunctivitis During the COVID-19 Pandemic Conjunctivitis, SARS-CoV-2 | Completed | Johns Hopkins University | 36 | 2020-05-18 | 2024-05-31 | |
| Efficacy and Safety of Saturno IIB Association on the Control of Ocular Inflammation Post-phacoemulsification SATURNO II association, Vigadexa® - Ocular Inflammation, Cataract | Phase 2 | Completed | EMS | 118 | 2020-02-27 | 2022-03-07 |
| Corneal Epithelial Stem Cells and Dry Eye Disease Corneal Epithelial Stem Cell Transplant - Dry Eye Syndromes, Dry Eye | Not applicable | Completed | Sloan W. Rush, MD | 17 | 2019-02-01 | 2022-04-21 |
| Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease Lifitegrast - Ocular Discomfort, Ocular Inflammation | Phase 4 | Withdrawn | University of Alabama at Birmingham | 2019-01-01 | 2019-05-17 | |
| KPI-121 1% Versus Prednisolone for the Treatment of Inflammation Following Cataract Surgery in Children KPI-121 1%, Prednisolone acetate - Ocular Inflammation | Phase 3 | Terminated | Kala Pharmaceuticals, Inc. | 2 | 2018-07-03 | 2020-10-19 |
| PGE2 Levels in Patient Treated With NSAIDs Placebo, Dicloftil, Nevanac - Ocular Inflammation | Phase 3 | Completed | University of Trieste | 104 | 2018-04-25 | 2018-07-24 |
| Efficacy and Safety of PRO-155 on Inflammation of the Conjunctival Surface in Subjects With Grade I-III Pterygium vs Placebo. PRO-155, Placebo - Pterygium, Ocular Pain | Phase 4 | Completed | Laboratorios Sophia S.A de C.V. | 166 | 2017-12-13 | 2019-11-20 |
| Closed Eye Neutrophils in Dry Eye Disease Eye wash - Dry Eye, Ocular Inflammation | Not applicable | Completed | University of Alabama at Birmingham | 153 | 2017-11-08 | 2019-05-17 |
| LE Gel for the Treatment of Ocular Inflammation and Pain Following Cataract Surgery Loteprednol Etabonate Ophthalmic Gel dosed TID, Loteprednol Etabonate Ophthalmic Gel dosed BID, Vehicle Gel - Cataract, Pain | Phase 3 | Completed | Bausch & Lomb Incorporated | 600 | 2016-06-01 | 2021-01-08 |
| RTA 408 Ophthalmic Suspension for the Prevention of Corneal Endothelial Cell Loss Following Cataract Surgery - GUARD Vehicle Ophthalmic Solution, Omaveloxolone Ophthalmic Suspension 0.5%, Omaveloxolone Ophthalmic Suspension 1% - Corneal Endothelial Cell Loss, Ocular Pain | Phase 2 | Completed | Biogen | 307 | 2014-05-31 | 2025-06-03 |
| Comparison Study of ISV-303 to Durasite Vehicle in Cataract Surgery Subjects ISV-303, DuraSite Vehicle - Ocular Inflammation | Phase 3 | Completed | Sun Pharmaceutical Industries Limited | 268 | 2013-05-01 | 2021-11-19 |
| Antibiotic Steroid Combination Compared With Individual Administration in the in the Treatment of Ocular Inflammation and Infection azithromycin 1.5%/Loteprednol 0,5% + placebo, azithromycin 1.5% + Loteprednol 0,5% (separately) - Ocular Inflammation, Infection Associated Blepharitis | Phase 3 | Withdrawn | Adapt Produtos Oftalmológicos Ltda. | 2012-12-01 | 2014-12-11 |
Showing 20 of 27. Sign in to see all of them.
Dry Eye Syndromes (5) · Cataract (4) · Blepharitis (2) · Conjunctivitis (2) · Eye Pain (2) · Inflammation (2) · Keratoconjunctivitis Sicca (2) · Postoperative Complications (2) · COVID-19 (1) · Chronic recurrent multifocal osteomyelitis (1) · Conjunctivitis, Bacterial (1) · Conjunctivitis, Viral (1) · Corneal Endothelial Cell Loss (1) · Epiretinal Membrane (1) · Eye Infections (1)
Eye Diseases (15) · Pathological Conditions, Signs and Symptoms (8) · Conjunctival Diseases (6) · Pathologic Processes (6) · Corneal Diseases (5) · Lacrimal Apparatus Diseases (5) · Lens Diseases (4) · Neurologic Manifestations (4) · Signs and Symptoms (4) · Conjunctivitis (3) · Keratitis (3) · Pain (3) · Eye Manifestations (2) · Eyelid Diseases (2) · Infections (2)
bromfenac (5) · prednisolone acetate (3) · Triamcinolone Acetonide (2) · Azithromycin (1) · Calcium Dobesilate (1) · Dexamethasone (1) · Fluorometholone (1) · Hydrocortisone (1) · Indomethacin (1) · Loteprednol Etabonate (1) · Lubricant Eye Drops (1) · Methylprednisolone (1) · Moxifloxacin (1) · Ophthalmic Solutions (1) · Povidone (1)
Bausch & Lomb Incorporated (3) · Sun Pharmaceutical Industries Limited (3) · University of Alabama at Birmingham (2) · Adapt Produtos Oftalmológicos Ltda. (1) · Agnes (1) · Biogen (1) · Campus Bio-Medico University (1) · EMS (1) · Evolutec Group (1) · Eximore Ltd. (1) · Harrow Inc (1) · ICON Bioscience Inc (1) · Johns Hopkins University (1) · Kala Pharmaceuticals, Inc. (1) · Laboratorios Sophia S.A de C.V. (1)
United States (14) · Brazil (2) · Italy (2) · Mexico (2) · France (1) · Ireland (1)
Kelly K Nichols, OD MPH PhD (2) · Alyson J Berliner, MD/PhD (1) · Denise Ramjit (1) · Jasmine Francis, MD (1) · Joshua Davidson, OD, FAAO (1) · Katherine Talcott, M.D. (1) · Laura Trusso (1) · Marco R Pastore, MD (1) · Mark Packer, MD (1) · Nallely Ramos Betancourt, Dr. (1) · Neal Shorstein, MD (1) · Paul Mullaney, FRCOphth (1) · Rubens Belfort Jr., MD (1) · Sezen Karakus, MD (1)
PMID 15948994, PMID 16021174, PMID 17054241, PMID 22511024, PMID 24695688, PMID 26783543, PMID 28819932, PMID 40630265