14 completed, 6 unknown, 5 recruiting, 2 withdrawn. 10 Not applicable, 5 Phase 2, 2 Phase 3, 1 Phase 1, 1 Phase 4.
Follow Corneal Endothelial Cell Loss: new trials by email Literature Review of Corneal Endothelial Cell Loss trials Research Report on Corneal Endothelial Cell Loss
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of EO2002 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction 150K cells, 500K cells, Placebo - Corneal Edema, Fuchs | Phase 2 | Recruiting | Emmecell | 121 | 2026-10-01 | 2026-10-09 |
| A Study of CA201A Eye Drops to Prevent Corneal Endothelial Cell Loss in Patients Undergoing Cataract Surgery Ophthalmic solution (matching formulation without ascorbic acid), Ascorbic acid ophthalmic solution 5% - Corneal Endothelial Cell Loss, Corneal Endothelial Damage Following the Hard Nuclear Cataract Surgery | Phase 2 | Recruiting | Caravel Oculus Pty Ltd | 200 | 2026-07-28 | 2026-08-06 |
| Effect of Systemic Ozone Therapy on Corneal Endothelium Systemic Ozone Therapy - Corneal Endothelial Cell Loss, Ozone Therapy | Not applicable | Completed | Yuzuncu Yil University | 96 | 2026-01-14 | 2026-07-21 |
| Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts Oral Vitamin C, Placebo - Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery | Not applicable | Recruiting | Universitas Indonesia | 120 | 2024-12-07 | 2025-01-17 |
| The Viability Control of Human Endothelial Cells Before Keratoplasty (V-CHECK) Study V-Check - Corneal Transplant Failure, Corneal Endothelial Cell Loss | Recruiting | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 135 | 2023-12-01 | 2025-10-02 | |
| Corneal Endothelium in Diabetics Undergoing Phacoemulsification Corneal Endothelial Cell Loss | Unknown | Assiut University | 50 | 2023-11-01 | 2023-02-21 | |
| Safety and Tolerability of EO2002 EO2002, Sham injection - Cataract, Endothelial Cell Loss, Corneal | Phase 1 | Recruiting | Asociación para Evitar la Ceguera en México | 32 | 2022-08-30 | 2025-12-08 |
| Endothelial Changes in Pseudoexfoliation Syndrome Specular Microscopy - Endothelial Cell Loss, Corneal | Unknown | Assiut University | 100 | 2022-02-01 | 2022-01-31 | |
| Quantification of Factors Influencing Endothelial Damage During Phacoemulsification Cataract surgery by phacoemulsification - Endothelial Cell Loss, Corneal, Cataract | Completed | Centre Hospitalier Régional Metz-Thionville | 121 | 2022-01-12 | 2022-09-10 | |
| Anterior Versus Posterior Artisan Intraocular Lens Fixation in Aphakic Children With Insufficient Capsular Support. Anterior enclavation, Posterior enclavation - Cataracts Infantile, Subluxation of Lens | Not applicable | Completed | Cairo University | 32 | 2022-01-01 | 2024-05-02 |
| Comparison of Phacoemulsification and Corneal Damage Between FLACS and Standard Phaco With Two Handpieces Femtosecond laser assisted cataract surgery with Active Sentry handpiece, Standard phacoemulsification with the Active Sentry handpiece, Standard phacoemulsification with the OZil handpiece - Corneal Endothelial Cell Loss, Cataract | Not applicable | Withdrawn | Centre hospitalier de l'Université de Montréal (CHUM) | 2021-12-01 | 2026-03-19 | |
| Changes in Corneal Endothelial Cell Density After Transscleral ab Interno Glaucoma Gel Stent Implantation XEN45 - Glaucoma, Endothelial Cell Loss, Corneal | Completed | Paracelsus Medical University | 129 | 2020-01-30 | 2021-07-13 | |
| Anterior Chamber Versus Scleral Fixated Intraocular Lens: Long-term Vision and Safety Outcomes Intraocular lens implantation - Corneal Endothelial Cell Loss, Secondary Intraocular Lens | Unknown | Sunnybrook Health Sciences Centre | 60 | 2019-09-01 | 2023-11-27 | |
| Corneal Endothelium After Phacoemulsification in Pseudo Exfoliation Syndrome phacoemulsification - Corneal Endothelial Cell Loss, Pseudoexfoliation Syndrome | Not applicable | Completed | Minia University | 40 | 2019-03-01 | 2022-09-13 |
| Effect of Intracameral Injection of Mydriatic Plus Anaesthetic Combination on Corneal Endothelial Count in Phaco Fydrane®: (Manufacturer DELPHARM TOURS, FRANCE). - Corneal Endothelial Cell Loss, Mydriasis | Phase 3 | Completed | Cairo University | 30 | 2019-02-01 | 2020-05-20 |
| Ripasudil 0.4% Eye Drops in Fuchs Endothelial Corneal Dystrophy Ripasudil eye drops, Optive eye drops, Descemetorhexis - Fuchs' Endothelial Dystrophy, Fuchs Dystrophy | Phase 2 | Unknown | University of Erlangen-Nürnberg Medical School | 21 | 2018-06-05 | 2018-07-12 |
| Effect of Intracameral Dexamethasone After Phacoemulsification in Diabetics on Corneal Endothelial Cell Density Dexamethasone, Saline Solutions, Intraocular - Diabetes Mellitus, Corneal Endothelial Cell Loss | Phase 4 | Withdrawn | Cairo University | 2018-01-01 | 2019-07-24 | |
| Corneal Endothelial Cell Loss After Trabeculectomy Versus Phakotrabeculectomy Trabeculectomy, Phako-trabeculectomy - Corneal Endothelial Cell Loss, Glaucoma | Not applicable | Completed | Sunnybrook Health Sciences Centre | 25 | 2017-09-01 | 2023-04-13 |
| Protecting the Corneal Endothelium During Cataract Surgery Using the Anterior Capsule Rhexis protection shield - Endothelial Cell Loss, Corneal | Not applicable | Completed | Prim. Prof. Dr. Oliver Findl, MBA | 70 | 2016-03-02 | 2019-02-26 |
| Second Comparative Study of Specular Microscopes for Endothelial and Corneal Cell Measurements Topcon Specular Microscope SP-1P, Konan Specular Microscope CELLCHEK XL - Corneal Endothelial Cell Loss | Completed | Topcon Medical Systems, Inc. | 76 | 2015-02-01 | 2022-06-08 |
Showing 20 of 28. Sign in to see all of them.
Cataract (8) · Fuchs' Endothelial Dystrophy (3) · Glaucoma (2) · Aphakia (1) · Astigmatism (1) · Corneal Dystrophy, Posterior Polymorphous, 1 (1) · Corneal Edema (1) · Corneal Endothelial Dystrophy 1 (1) · Corneal endothelial dystrophy type 2 (1) · Diabetes Mellitus (1) · Exfoliation Syndrome (1) · Eye Pain (1) · Intraocular Lymphoma (1) · Joint Dislocations (1)
Corneal Diseases (28) · Eye Diseases (28) · Eye Manifestations (28) · Pathologic Processes (28) · Pathological Conditions, Signs and Symptoms (28) · Postoperative Complications (28) · Signs and Symptoms (28) · Lens Diseases (9) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3) · Corneal Dystrophies, Hereditary (3) · Eye Diseases, Hereditary (3) · Genetic Diseases, Inborn (3) · Ocular Hypertension (2) · Endocrine System Diseases (1) · Eye Neoplasms (1)
Ascorbic Acid (2) · Calcium Dobesilate (1) · Dexamethasone (1) · Lasers (1) · Lens Implantation, Intraocular (1) · Ophthalmic Solutions (1) · Phacoemulsification (1) · Sodium Chloride (1) · Sulfur Hexafluoride (1) · Trabeculectomy (1) · Vitrectomy (1) · salicylhydroxamic acid (1)
Cairo University (3) · Sunnybrook Health Sciences Centre (3) · Assiut University (2) · Topcon Medical Systems, Inc. (2) · Asociación para Evitar la Ceguera en México (1) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (1) · Biogen (1) · Caravel Oculus Pty Ltd (1) · Centre Hospitalier Régional Metz-Thionville (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · EDUARD PEDEMONTE-SARRIAS (1) · Emmecell (1) · Khon Kaen University (1) · Minia University (1) · Nidek Co. LTD. (1)
United States (6) · Canada (4) · Egypt (3) · Germany (2) · Spain (2) · Australia (1) · Austria (1) · Belgium (1) · France (1) · Indonesia (1) · Iran (1) · Italy (1) · Mexico (1) · Netherlands (1) · Thailand (1)
Ahmed A Abdel Azim, MD (1) · Ahmed A. Dahab, MD (1) · Alireza Baradaran Raffiee, MD (1) · Ayman GA Elnahry, Msc (1) · Catherine Birt, MD (1) · David Hwang, MD (1) · Eduard Pedemonte-Sarrias, MD (1) · Gail Torkildsen, MD (1) · Georges Durr, MD, FRCSC (1) · Hatem Saeed, MD (1) · Jean Marc Perone (1) · Noelia Kunzevitzky, PhD (1) · Peter Kertes, MD (1) · Peter Kertes, MD, CM, FRCSC (1) · Shaimaa A Arfeen, MD (1)
2017 (1)