37 completed, 4 unknown, 1 recruiting, 1 terminated. 24 Phase 4, 9 Phase 3, 5 Phase 2, 4 Phase 1, 2 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 24 | Completed 23, Unknown 1 |
| Phase 3 | 9 | Completed 8, Terminated 1 |
| Phase 2 | 5 | Completed 3, Unknown 1, Withdrawn 1 |
| Phase 1 | 4 | Completed 2, Unknown 2 |
| Not applicable | 2 | Completed 1, Recruiting 1 |
Follow bromfenac: new trials by email Literature Review of bromfenac trials Research Report on bromfenac
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Efficacy of Bromfenac 0.09%, Nepafenac 0.3% and Diclofenac 0.1% in Patients After Cataract Surgery Bromfenac 0.09 % Ophthalmic Solution, Nepafenac 0.3% Oph Susp, diclofenac 0.1% ophthalmic susp. - Macular Oedema, Cataract Surgery | Not applicable | Recruiting | Nemocnice Kolín | 150 | 2025-08-01 | 2025-09-17 |
| Assessing eFficacy and Safety of DEXTENZA 0.4 mg inseRt, Following Cataract Surgery Dextenza 0.4Mg Ophthalmic Insert, Prednisolone Acetate 1% Oph Susp, Prolensa 0.07% Ophthalmic Solution - Corneal Edema, Corneal Defect | Phase 4 | Completed | Nicole Fram M.D. | 50 | 2023-06-01 | 2026-02-20 |
| Effects of Bromfenac on Macular Thickness After Phacoemulsification Surgery Bromfenac, Moxifloxacin 0.5% ophthalmic solution, Dexamethasone phosphate 0.1% - Cataract, Cystoid Macular Edema After Phacoemulsification | Phase 4 | Completed | Inas Abd | 87 | 2023-05-01 | 2025-05-06 |
| Bromfenac Sodium Hydrate Eye Drops in Familial Exudative Vitreoretinopathy Bromfenac Sodium - Familial Exudative Vitreoretinopathies | Phase 2 | Unknown | Seoul National University Hospital | 39 | 2021-11-01 | 2023-11-22 |
| Effectiveness of Periocular Drug Injection in CATaract Surgery Bromfenac, Dexamethasone, Triamcinolone Acetonide - Macular Edema, Cystoid Macular Edema | Phase 3 | Terminated | Luigi Rondas | 628 | 2021-10-13 | 2024-11-04 |
| Pilocarpine, Brimonidine, Oxymetazoline (PBO) Compound to Control Presbyopia Symptoms Pilocarpine, brimonidine, oxymetazoline, hyaluronic acid, bromfenac (PBOHB) compound - Presbyopia | Phase 1 | Unknown | Optall Vision | 11 | 2021-08-14 | 2021-08-17 |
| Comparison of a Compound With Pilocarpine and Brimonidine to Improve Near Vision in Healthy Presbyopic Patients Compound Pilocarpine, Brimonidine, Oxymetazoline, Hyaluronic acid, Bromfenac, Pilocarpine Hydrochloride, Brimonidine Tartrate - Presbyopia | Phase 1 | Unknown | Optall Vision | 11 | 2021-08-10 | 2021-08-19 |
| PCME Prevention in Patients With NPDR Bromfenac Ophthalmic 0.09% Ophthalmic Solution, Dexamethasone Ophthalmic, Placebo - Cystoid Macular Edema Following Cataract Surgery | Phase 4 | Completed | Klinički Bolnički Centar Zagreb | 90 | 2021-05-01 | 2022-05-20 |
| NSAID vs Steroid in Trabeculectomy Wound Management Bromfenac 0.07% Oph Susp, Dexamethasone - Glaucoma | Phase 4 | Unknown | Cindy Hutnik | 150 | 2020-11-01 | 2020-10-19 |
| Efficacy of Nonsteroidal Anti-Inflammatory Drugs for the Prevention of Cystoid Macular Edema Following Cataract Phacoemulsification Bromfenac 0.09 % Ophthalmic Solution, Nepafenac 0.1% eyedrops, diclofenac 0.1% ophthalmic susp. - Pseudophakic Cystoid Macular Edema | Phase 4 | Completed | Pomeranian Medical University Szczecin | 88 | 2020-10-14 | 2026-07-10 |
| A Prospective Clinical Study Evaluating Dexycu vs Prednisolone Acetate 1% Dexycu intracameral dexamethasone, Prednisolone Acetate - Cataract | Phase 4 | Completed | Research Insight LLC | 31 | 2019-12-16 | 2020-12-11 |
| Control of Pain in Intravitreal Injections Using Topical NSAIDs Bromfenac, Artificial tears - Intravitreal Injections, IVI | Phase 4 | Completed | University of Wisconsin, Madison | 46 | 2019-06-27 | 2023-06-12 |
| Prophylactic Treatment: Lessdrops™ vs Standard Drops Regimen Pred-Gati-Brom, Prednisolone acetate 1% ophthalmic suspension, Gatifloxacin Ophthalmic - Cataract | Phase 4 | Completed | Carolina Eyecare Physicians, LLC | 35 | 2018-06-22 | 2022-06-10 |
| PGE2 Levels in Patient Treated With NSAIDs Placebo, Dicloftil, Nevanac - Ocular Inflammation | Phase 3 | Completed | University of Trieste | 104 | 2018-04-25 | 2018-07-24 |
| Efficacy and Safety of PRO-155 on Inflammation of the Conjunctival Surface in Subjects With Grade I-III Pterygium vs Placebo. PRO-155, Placebo - Pterygium, Ocular Pain | Phase 4 | Completed | Laboratorios Sophia S.A de C.V. | 166 | 2017-12-13 | 2019-11-20 |
| Bromfenac Versus Dexamethasone After Cataract Surgery Bromfenac 0.09 % Ophthalmic Solution, Dexamethasone 0.1% ophthalmic suspension - Inflammation Eye | Phase 4 | Completed | Azienda USL Reggio Emilia - IRCCS | 92 | 2017-10-16 | 2025-06-25 |
| Effect of Bromfenac on Pain Related to Pterygium Surgery 0.1% bromfenac - Pterygium, Pain | Phase 4 | Completed | Zhongshan Ophthalmic Center, Sun Yat-sen University | 60 | 2016-10-01 | 2019-07-17 |
| NSAIDs and PGE2 Levels in Vitrectomy Patients Ketorolac 0.5% eyedrops, Indomethacin 0.5% eyedrops, Bromfenac 0.09% eyedrops - Vitreous Inflammation | Phase 3 | Completed | Università degli Studi di Brescia | 70 | 2014-03-01 | 2015-02-12 |
| Study Title: Clinical Outcomes of Prolensa (Bromfenac Ophthalmic Solution) 0.07% QD vs. Ilevro (Nepafenac Ophthalmic Suspension) 0.3% QD With Extra (Pulse) Dose on Day of Surgery for Treatment of Ocular Inflammation Associated With Cataract Surgery in a Randomized, Single Masked Clinical Trial Bromfenac, Nepafenac - Treatment of Ocular Inflammation Associated With Cataract Surgery | Phase 4 | Completed | Silverstein Eye Centers | 57 | 2013-10-30 | 2019-04-01 |
| PRevention of Macular EDema After Cataract Surgery Bromfenac, Dexamethasone, Bevacizumab - Cystoid Macular Edema, Cataract | Phase 3 | Completed | Maastricht University Medical Center | 1127 | 2013-07-10 | 2017-04-14 |
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Cataract (16) · Macular Edema (7) · Inflammation (3) · Eye Pain (2) · Pain (2) · Presbyopia (2) · Pterygium (2) · Conjunctivitis, Allergic (1) · Corneal Edema (1) · Diabetes Mellitus (1) · Dry Eye Syndromes (1) · Endophthalmitis (1) · Epiretinal Membrane (1) · Eye Diseases (1) · Familial Exudative Vitreoretinopathies (1)
Bp Consulting, Inc (5) · Sun Pharmaceutical Industries Limited (4) · Bausch & Lomb Incorporated (3) · Frank A. Bucci, Jr., M.D. (2) · Innovative Medical (2) · Laboratorios Sophia S.A de C.V. (2) · Optall Vision (2) · Azienda USL Reggio Emilia - IRCCS (1) · Carolina Eyecare Physicians, LLC (1) · Center For Excellence In Eye Care (1) · Cindy Hutnik (1) · Florida Eye Microsurgical Institute (1) · Inas Abd (1) · Johns Hopkins University (1) · Klinički Bolnički Centar Zagreb (1)
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Cesar Alejandro S Galeana, MD (2) · Alfredo Lizarraga-Corona, MD (1) · Alisa Kim, MD (1) · Andjela Jukic, MD, FEBO (1) · Barry Schechter, MD (1) · Carlos Buznego, MD (1) · Cindy Hutnik, MD (1) · David Rho, MD (1) · Frank A Bucci, Jr., MD (1) · Frank A Bucci, Jr.,, MD (1) · Frank Bucci, MD (1) · James Gills, MD (1) · Jeffrey Heier, MD (1) · Jeong Hun Kim, MD, PhD (1) · John Hovanesian, MD (1)
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