23 completed. 23 Phase 3, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 23 | Completed 23 |
| Phase 2 | 4 | Completed 4 |
Follow Obsessive-Compulsive Disorder: new trials by email Literature Review of Obsessive-Compulsive Disorder trials Research Report on Obsessive-Compulsive Disorder
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Study to Evaluate the Efficacy and Safety of Adjunctive Troriluzole in Obsessive-Compulsive Disorder Troriluzole, Placebo - Obsessive-Compulsive Disorder | Phase 3 | Completed | Biohaven Pharmaceuticals, Inc. | 589 | 2021-01-29 | 2026-05-22 |
| Efficacy and Safety Study of Adjunctive Troriluzole in Obsessive Compulsive Disorder Troriluzole, Placebo - Obsessive-Compulsive Disorder | Phase 3 | Completed | Biohaven Pharmaceuticals, Inc. | 456 | 2020-12-22 | 2026-01-07 |
| Dronabinol in Trichotillomania and Other Body Focused Repetitive Behaviors Dronabinol, Placebo - Trichotillomania, Skin-Picking | Phase 2 / Phase 3 | Completed | University of Chicago | 50 | 2018-10-01 | 2022-06-02 |
| Tolcapone in Obsessive Compulsive Disorder Tolcapone 200 MG - Obsessive-Compulsive Disorder | Phase 2 / Phase 3 | Completed | University of Chicago | 20 | 2018-03-20 | 2022-04-07 |
| Troriluzole (BHV-4157) in Adult Participants With Obsessive Compulsive Disorder Troriluzole, Placebo - Obsessive-Compulsive Disorder | Phase 2 / Phase 3 | Completed | Biohaven Pharmaceuticals, Inc. | 426 | 2017-12-19 | 2026-01-22 |
| A Phase 3 Study of Fluvoxamine (SME3110) in Pediatric/Adolescent Patients With Obsessive Compulsive Disorder Fluvoxamine maleate, Placebo - Obsessive Compulsive Disorder | Phase 3 | Completed | AbbVie | 38 | 2013-08-14 | 2017-12-04 |
| D-cycloserine Augmentation of Cognitive Behavioral Therapy (CBT) for Pediatric Obsessive-compulsive Disorder (OCD) Cognitive-behavioral therapy, d-cycloserine, Pill placebo - Obsessive-compulsive Disorder | Phase 3 | Completed | University of South Florida | 142 | 2011-06-01 | 2018-01-23 |
| Deep Brain Stimulation and Obsessive-compulsive Disorder Deep Brain Stimulation (DBS) - Obsessive-Compulsive Disorder | Phase 3 | Completed | University Hospital, Bordeaux | 31 | 2011-04-04 | 2020-02-06 |
| Intravenous Immunoglobulin for PANDAS Gamunex Intravenous Immunoglobulin, Placebo - Obsessive-Compulsive Disorder, Children | Phase 3 | Completed | National Institute of Mental Health (NIMH) | 48 | 2011-01-01 | 2020-03-17 |
| Comparison of DBS Targets in Obsessive-compulsive Disorder Deep brain stimulation - Obsessive-Compulsive Disorder | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 8 | 2010-10-01 | 2016-05-18 |
| Cognitive-Behavioral Treatment for Anxiety Disorders in Children With Autism Spectrum Disorders Cognitive-behavioral therapy, Treatment as Usual - Autism, Asperger's Syndrome | Phase 2 / Phase 3 | Completed | University of South Florida | 45 | 2010-04-01 | 2013-04-02 |
| Comparing the Effectiveness of Two Family-based Therapies in Treating Young Children With Obsessive-Compulsive Disorder Cognitive Behavior Therapy, Relaxation Therapy - Obsessive Compulsive Disorder | Phase 3 | Completed | Rhode Island Hospital | 127 | 2007-10-01 | 2013-03-11 |
| Tolerability and Efficacy of High Dose Escitalopram for the Treatment of Obsessive-Compulsive Disorder (OCD) escitalopram - Obsessive-Compulsive Disorder | Phase 3 | Completed | Abarbanel Mental Health Center | 100 | 2006-03-01 | 2006-07-26 |
| Memantine Treatment for Obsessive-compulsive Disorder and Generalized Anxiety Disorder Memantine - Obsessive-Compulsive Disorder, Generalized Anxiety Disorder | Phase 3 | Completed | University of California, Los Angeles | 17 | 2005-05-01 | 2019-05-10 |
| A Controlled Trial of Daily Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder Cognitive-behavioral therapy - Obsessive-Compulsive Disorder | Phase 3 | Completed | University of South Florida | 60 | 2004-10-01 | 2010-08-09 |
| Effectiveness of D-Cycloserine as an Aid to Enhance Learning for Individuals With OCD Receiving Behavior Therapy seromycin, Behavior Therapy - Obsessive-Compulsive Disorder | Phase 3 | Completed | Massachusetts General Hospital | 33 | 2003-11-01 | 2012-07-16 |
| Treatment of Obsessive Compulsive Disorder in Children Serotonin reuptake inhibitors management, Cognitive behavioral therapy by a psychologist, Instructional cognitive behavioral therapy by a psychiatrist - Obsessive-Compulsive Disorder | Phase 3 | Completed | Duke University | 124 | 2003-09-01 | 2014-07-29 |
| Study to Determine the Efficacy and Safety of Adjunctive Topiramate in the Treatment of Obsessive-Compulsive Disorder Topiramate - Obsessive-Compulsive Disorder | Phase 3 | Completed | University of Florida | 96 | 2003-01-01 | 2011-10-05 |
| Quetiapine Augmentation in Severe Obsessive Compulsive Disorder quetiapine fumarate, SSRI/Clomipramine - Obsessive Compulsive Disorder | Phase 3 | Completed | AstraZeneca | 44 | 2002-04-01 | 2007-12-18 |
| Family Based Treatment of Early Childhood Obsessive Compulsive Disorder Cognitive Behavioral Therapy (CBT), Relaxation Training - Obsessive-Compulsive Disorder | Phase 3 | Completed | Rhode Island Hospital | 38 | 2002-03-01 | 2014-05-07 |
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Anxiety Disorders (3) · Generalized Anxiety Disorder (3) · Anxiety, Separation (2) · Phobia, Social (2) · Asperger Syndrome (1) · Autistic Disorder (1) · Autoimmune Diseases (1) · Compulsive Behavior (1) · Excoriation Disorder (1) · Obsessive Behavior (1) · Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal infections (1) · Trichotillomania (1)
Mental Disorders (23) · Anxiety Disorders (20) · Behavior (2) · Behavioral Symptoms (2) · Neurodevelopmental Disorders (2) · Phobic Disorders (2) · Autism Spectrum Disorder (1) · Child Development Disorders, Pervasive (1) · Disruptive, Impulse Control, and Conduct Disorders (1) · Immune System Diseases (1) · Impulsive Behavior (1) · Self-Injurious Behavior (1)
Cognitive Behavioral Therapy (6) · Fluvoxamine (3) · Relaxation Therapy (3) · Behavior Therapy (2) · Counseling (2) · Cycloserine (2) · Deep Brain Stimulation (2) · Escitalopram (2) · Psychotherapy (2) · Sertraline (2) · Citalopram (1) · Clomipramine (1) · Dronabinol (1) · Family Therapy (1) · Fluoxetine (1)
Biohaven Pharmaceuticals, Inc. (3) · National Institute of Mental Health (NIMH) (3) · University of South Florida (3) · Rhode Island Hospital (2) · University of Chicago (2) · Abarbanel Mental Health Center (1) · AbbVie (1) · Assistance Publique - Hôpitaux de Paris (1) · AstraZeneca (1) · Duke University (1) · Massachusetts General Hospital (1) · University Hospital, Bordeaux (1) · University of California, Los Angeles (1) · University of Florida (1) · University of Pennsylvania (1)
United States (16) · France (2) · Canada (1) · China (1) · Germany (1) · Israel (1) · Italy (1) · Netherlands (1) · Spain (1) · United Kingdom (1)
Alexander Bystritsky, MD (1) · Edna B. Foa, PhD (1) · Eric A Storch, Ph.D. (1) · Eric Storch, Ph.D. (1) · Eric Storch, PhD (1) · Herbert E Ward, MD (1) · Jennifer B. Freeman, PhD (1) · John C. Piacentini, PhD (1) · John S March, MD MPH (1) · John S. March, MD (1) · John S. March, MD, MPH (1)
PMID 18090508, PMID 18356758, PMID 18356759, PMID 19183470, PMID 19204653, PMID 20855047, PMID 21934055, PMID 22024003, PMID 23357440, PMID 23774008, PMID 24759852, PMID 25457929, PMID 27166296, PMID 27663941, PMID 28412602, PMID 29233751, PMID 34582562, PMID 34825898
R01MH055121 (1), R01MH055126 (1), R01MH079217 (1), R10MH055121 (1), R21MH060669 (1)