22 completed, 12 unknown, 7 recruiting, 6 active not recruiting. 18 Not applicable, 6 Phase 4, 2 Phase 3.
Follow NSTEMI - Non-ST Segment Elevation MI: new trials by email Literature Review of NSTEMI - Non-ST Segment Elevation MI trials Research Report on NSTEMI - Non-ST Segment Elevation MI
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| AI-ECG Detection of Occlusion Myocardial Infarction at Emergency Department Triage (TRIACS) Acute Coronary Syndromes, Chest Pain | Not yet recruiting | University Medical Centre Maribor | 1000 | 2026-10-19 | 2026-10-20 | |
| Aspirin-free Strategy With Ticagrelor in Patients With a Myocardial Infarction Treated Medically Alone Ticagrelor + placebo, Ticagrelor + aspirin - NSTEMI - Non-ST Segment Elevation MI, STEMI (ST Elevation MI) | Phase 3 | Recruiting | Montreal Heart Institute | 2570 | 2026-03-03 | 2026-03-10 |
| Efficacy of Immediate Versus Staged Complete Revascularization in Patients With NSTE-ACS and Multivessel Disease (FUTURE II) Immediate Complete Revascularization, Staged Complete Revascularization - NSTEMI, NSTEMI - Non-ST Segment Elevation MI | Not applicable | Not yet recruiting | RenJi Hospital | 1904 | 2026-02-28 | 2026-01-30 |
| Advanced NanoTherapies Dual-API DCB to Treat De-Novo and ISR Lesions in Patients With Symptomatic Coronary Artery Disease SirPlux Duo™ Dual API-Coated PTCA Balloon Catheter - Angina (Stable), CAD - Coronary Artery Disease | Not applicable | Recruiting | Advanced NanoTherapies | 30 | 2025-12-15 | 2026-01-27 |
| Breaking Fasts Ahead of Cardiac Caths Non-Fasting, Fasting - Stable Angina (SA), Unstable Angina (UA) | Not applicable | Recruiting | University of South Florida | 400 | 2025-10-13 | 2025-12-16 |
| AI-Powered ECG Detecting Culprit Vessel Blood Flow Abnormality in ACS Acute Coronary Syndrome, STEMI | Active not recruiting | Powerful Medical | 800 | 2024-12-10 | 2026-03-20 | |
| TIRANA-ACS: A Prospective Registry Study for the Targeted Investigation of Residual Inflammation After Non-ST/ ST Elevation Acute Coronary Syndrome ACS (Acute Coronary Syndrome), Myocardial Infarction (MI) | Recruiting | University Hospital Centre Mother Teresa | 1600 | 2024-11-01 | 2025-09-30 | |
| MAchine Learning to Boost the Early Diagnosis of Acute Cardiovascular Conditions Machine learning based development of a diagnostic tool for acute cardiovascular disease - Acute Cardiovascular Disease, ST-segment Elevation Myocardial Infarction (STEMI) | Recruiting | University Hospital, Basel, Switzerland | 200000 | 2024-04-01 | 2025-04-15 | |
| Diagnostic Performance of Artificial Intelligence Algorithms in Prediction of Acute Coronary Syndrome Based on White Blood Cell Properties Acute Coronary Syndrome, Angina Pectoris | Recruiting | RobotDreams GmbH | 3350 | 2024-02-01 | 2026-06-24 | |
| MCG Discovery Study in Emergency Departments Sponsor MCG device - ACS - Acute Coronary Syndrome, NSTEMI - Non-ST Segment Elevation MI | Not applicable | Completed | SB Technology, Inc. | 124 | 2023-10-30 | 2025-10-21 |
| What is the Optimal Antithrombotic Strategy in Patients With Atrial Fibrillation Undergoing PCI? 30-day DAPT, Guideline-directed therapy - Acute Coronary Syndrome, Myocardial Infarction | Phase 4 | Recruiting | St. Antonius Hospital | 2000 | 2023-01-11 | 2023-12-15 |
| Can Escalation Reduce Acute Myocardial Infarction Mortality in Cardiogenic Shock Cardiogenic Shock, Acute Myocardial Infarction | Active not recruiting | Henry Ford Health System | 124 | 2022-07-22 | 2026-04-17 | |
| Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia Research-based genetic test for Familial Hypercholesterolemia - Familial Hypercholesterolemia, Familial Hypercholesterolemia Due to Genetic Defect of Apolipoprotein B | Not applicable | Completed | University of British Columbia | 140 | 2022-01-01 | 2026-05-01 |
| Evolocumab or Normal Strategies to Reach LDL Objectives in Acute Myocardial Infarction Upbound to PCI Evolocumab 140 MG/ML, Standard of care (SOC) - STEMI - ST Elevation Myocardial Infarction, NSTEMI - Non-ST Segment Elevation MI | Phase 4 | Active not recruiting | Assistance Publique - Hôpitaux de Paris | 2166 | 2021-09-29 | 2026-04-13 |
| Prehospital Triage of Patients With Suspected Non-ST-segment Elevation Acute Coronary Syndrome: the TRIAGE-ACS Study PreHEART - ACS, NSTEMI - Non-ST Segment Elevation MI | Completed | Catharina Ziekenhuis Eindhoven | 1071 | 2021-04-01 | 2024-02-12 | |
| A Multicenter Study on Early Diagnosis of NSTE-ACS Patients Based on Machine Learning Model The model of machine learning - NSTEMI - Non-ST Segment Elevation MI, Unstable Angina | Unknown | First Affiliated Hospital of Xinjiang Medical University | 2500 | 2020-12-20 | 2020-12-31 | |
| The FAST OCT Study Optical coherence tomography assessment - Tomography, Optical Coherence, Myocardial Revascularization | Not applicable | Unknown | Erasmus Medical Center | 200 | 2020-12-01 | 2020-12-24 |
| Emergency Department Triage of Patients With Acute Chest Pain Based on the ESC 0/1-hour Algorithm (PRESC1SE-MI) European Society of Cardiology hs-cTnT/I 0 h/1 h algorithm, European Society of Cardiology hs-cTnT/I 0 h/3 h algorithm - Acute Chest Pain, NSTEMI - Non-ST Segment Elevation MI | Not applicable | Active not recruiting | University Hospital, Basel, Switzerland | 64374 | 2020-12-01 | 2026-09-17 |
| Drug Coated Balloon for Side Branch Treatment vs. Conventional Approach in True Bifurcation Coronary Disease: PRO-DAVID Provisional DCB approach PCI procedure, Standard provisional approach PCI procedure - Stable Angina, Ischemic Heart Disease | Not applicable | Unknown | Clinical Hospital Center Rijeka | 800 | 2020-10-01 | 2020-05-27 |
| MBCT Delivered Via Group Videoconferencing for ACS Syndrome Patients With Depressive Symptoms MBCT intervention for ACS patients - Acute Coronary Syndrome, Depression | Not applicable | Completed | Massachusetts General Hospital | 8 | 2020-04-24 | 2023-04-24 |
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Non-ST Elevated Myocardial Infarction (50) · ST Elevation Myocardial Infarction (28) · Acute Coronary Syndrome (21) · Angina, Unstable (18) · Myocardial Infarction (13) · Coronary Artery Disease (10) · Angina, Stable (9) · Chest Pain (3) · Angina Pectoris (2) · Coronary Stenosis (2) · Depression (2) · Emergencies (2) · Hemorrhage (2) · Myocardial Ischemia (2) · Shock, Cardiogenic (2)
Cardiovascular Diseases (50) · Heart Diseases (50) · Infarction (50) · Necrosis (50) · Pathologic Processes (50) · Pathological Conditions, Signs and Symptoms (50) · Vascular Diseases (50) · Ischemia (49) · Myocardial Ischemia (48) · Myocardial Infarction (37) · Neurologic Manifestations (20) · Pain (20) · Signs and Symptoms (20) · Angina Pectoris (17) · Chest Pain (17)
Clopidogrel (2) · Ticagrelor (2) · 2'-deoxythymidylyl-(3'-5')-2'-deoxyadenosine (1) · Algorithms (1) · Angptl4 protein, mouse (1) · Aspirin (1) · Blood Specimen Collection (1) · Microvascular Density (1) · Standard of Care (1) · Tomography, Optical Coherence (1) · cangrelor (1) · evolocumab (1)
Charite University, Berlin, Germany (2) · Henry Ford Health System (2) · Massachusetts General Hospital (2) · University Hospital, Basel, Switzerland (2) · Abiomed Inc. (1) · Advanced NanoTherapies (1) · Assistance Publique - Hôpitaux de Paris (1) · Assiut University (1) · Azienda Ospedaliero Universitaria di Sassari (1) · Biosensors Europe SA (1) · CGBio Inc. (1) · Catharina Ziekenhuis Eindhoven (1) · CeloNova BioSciences, Inc. (1) · Centre hospitalier de l'Université de Montréal (CHUM) (1) · Clinical Hospital Center Rijeka (1)
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William W O'Neill, MD (2) · Aikeliyaer Ainiwaer, M.D (1) · Alban Dibra, Prof. Dr, Phd (1) · Andi Rroku, MD (1) · Babar Basir, DO (1) · Christian Spaulding, MD (1) · Christina Luberto, PhD (1) · Christina M Luberto, PhD (1) · Craig Thompson, MD (1) · Dan Atar, MD, PhD (1) · David M Leistner, MD (1) · Deiti Prvulovic, MD, PhD (1)
PMID 10460813, PMID 10858178, PMID 11253156, PMID 11495621, PMID 12241831, PMID 12622581, PMID 14581255, PMID 15063816, PMID 15625341, PMID 15660036, PMID 15824056, PMID 15864236, PMID 16129869, PMID 16423872, PMID 16757543, PMID 16925605, PMID 17387132, PMID 17502590, PMID 17982163, PMID 18036459, PMID 18387940, PMID 18929686, PMID 19463511, PMID 19619694, PMID 20359842, PMID 20661139, PMID 21420046, PMID 21421184, PMID 22064593, PMID 22491499, PMID 22922414, PMID 22995877, PMID 22999128, PMID 23127386, PMID 23256914, PMID 23333655, PMID 23644488, PMID 23652265, PMID 24407049, PMID 24799502, PMID 26740483, PMID 26794722, PMID 27305194, PMID 30408229, PMID 31025538, PMID 31298551, PMID 31325044, PMID 32719074, PMID 33033102, PMID 33080003
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