4 completed, 2 unknown, 1 active not recruiting, 1 not yet recruiting. 10 Phase 2, 5 Phase 3, 1 Phase 1.
Follow Neonatal Sepsis: new trials by email Literature Review of Neonatal Sepsis trials Research Report on Neonatal Sepsis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women GBS-NN/NN2 vaccine - Streptococcus Agalactiae Infection, Neonatal Sepsis | Phase 2 / Phase 3 | Active not recruiting | Minervax ApS | 137 | 2025-03-07 | 2026-09-04 |
| Intravenous Methylene Blue for Treating Refractory Neonatal Septic Shock Methylene Blue, Placebo - Neonatal Sepsis, Shock, Septic | Phase 2 / Phase 3 | Not yet recruiting | Post Graduate Institute of Medical Education and Research, Chandigarh | 130 | 2024-03-15 | 2024-03-12 |
| A Comparative Analysis of 4% Chlorhexidine Versus Methylated Spirit as Prophylaxis of Omphalitis and Sepsis in Newborns Chlorhexidine Topical Cream, Methylated Spirit - Neonatal Sepsis, Omphalitis | Phase 2 | Completed | Sheikh Zayed Federal Postgraduate Medical Institute | 300 | 2020-09-12 | 2023-08-23 |
| Olive Oil Massage Effect for Reduction of Preterm Sepsis (OMEPS) Olive Oil Massage - Sepsis, Pre-Term | Phase 2 / Phase 3 | Unknown | King Abdullah International Medical Research Center | 300 | 2020-09-01 | 2021-01-20 |
| Methylene Blue Versus Vasopressin Analogue for Treatment of Septic Shock in Preterm Neonate Methylene Blue - Neonatal Sepsis, Refractory Shock | Phase 2 | Unknown | Ain Shams University | 36 | 2019-02-19 | 2019-10-01 |
| Intravenous and Oral Fosfomycin in Hospitalised Neonates With Clinical Sepsis Standard of Care + Fosfomycin, PK, Analysis of Bacterial Isolates - Neonatal SEPSIS | Phase 2 | Completed | Drugs for Neglected Diseases | 120 | 2018-03-15 | 2020-02-17 |
| Neonatal Vancomycin Trial Vancomycin - Late Onset Neonatal Sepsis | Phase 2 | Terminated | PENTA Foundation | 242 | 2017-02-27 | 2020-09-09 |
| Effects of Melatonin as a Novel Antioxidant and Free Radicals Scavenger in Neonatal Sepsis Melatonin 10 mg, Conventional treatment of neonatal sepsis - Neonatal Sepsis | Phase 1 / Phase 2 | Completed | Mohamed Hussein Metwally | 55 | 2015-11-26 | 2017-09-27 |
| Chlorhexidine Skin Application for Prevention of Infection in Infants Weighing <1500 g at Birth 0.25% chlorhexidine, sterile water - Neonatal Sepsis, Neonatal Mortality Rate | Phase 2 / Phase 3 | Withdrawn | All India Institute of Medical Sciences | 2012-11-01 | 2016-07-18 | |
| Antibiotic Prophylaxis in Prelabor Rupture of Membranes at Term Ampicillin + gentamicin - Chorioamnionitis, Puerperal Endometritis | Phase 2 / Phase 3 | Completed | Hospital de Santa Maria, Portugal | 161 | 2008-10-01 | 2016-11-28 |
Sepsis (3) · Shock, Septic (2) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1) · Chorioamnionitis (1) · Endometritis (1) · Fetal Membranes, Premature Rupture (1) · Gram-Positive Bacterial Infections (1) · Infections (1) · Meningitis (1) · Pneumonia (1) · Premature Birth (1) · Shock (1) · Streptococcal Infections (1)
Congenital, Hereditary, and Neonatal Diseases and Abnormalities (10) · Infant, Newborn, Diseases (10) · Inflammation (10) · Pathologic Processes (10) · Pathological Conditions, Signs and Symptoms (10) · Systemic Inflammatory Response Syndrome (10) · Infections (9) · Sepsis (7) · Female Urogenital Diseases and Pregnancy Complications (2) · Obstetric Labor Complications (2) · Pregnancy Complications (2) · Urogenital Diseases (2) · Adnexal Diseases (1) · Female Urogenital Diseases (1) · Fetal Diseases (1)
Methylene Blue (2) · Ampicillin (1) · Chlorhexidine (1) · Fosfomycin (1) · Gentamicins (1) · Melatonin (1) · Saline Solution (1) · Standard of Care (1) · Terlipressin (1) · Vancomycin (1)
Ain Shams University (1) · All India Institute of Medical Sciences (1) · Drugs for Neglected Diseases (1) · Hospital de Santa Maria, Portugal (1) · King Abdullah International Medical Research Center (1) · Minervax ApS (1) · Mohamed Hussein Metwally (1) · PENTA Foundation (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Sheikh Zayed Federal Postgraduate Medical Institute (1)
India (2) · Denmark (1) · Egypt (1) · Estonia (1) · Greece (1) · Italy (1) · Kenya (1) · Pakistan (1) · Portugal (1) · Saudi Arabia (1) · South Africa (1) · Spain (1) · United Kingdom (1)
Filipa Faria Vaz Passos, Dr (1) · James A Berkley, Prof (1) · Jubara Alallah (1) · Mike Sharland, MD, FRCPCH (1) · Sourabh Dutta, MD, PhD (1) · Vinod K Paul, MD, PhD (1)
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