21 completed. 21 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 21 | Completed 21 |
| Phase 2 | 4 | Completed 4 |
Follow Menopause: new trials by email Literature Review of Menopause trials Research Report on Menopause
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Neurosteroid Intervention for Menopausal and Perimenopausal Depression Pregnenolone, Placebo - Major Depressive Disorder, Menopause | Phase 1 / Phase 2 | Completed | University of Texas Southwestern Medical Center | 73 | 2018-09-01 | 2026-01-22 |
| Inovium Ovarian Rejuvenation Trials Autologous PRP injection into human ovarian tissue - Perimenopausal Disorder, Menopause | Phase 1 | Completed | Ascendance Biomedical | 200 | 2017-06-01 | 2020-04-20 |
| Use of Estriol at Distal Third of Vagina Improving Coital Pain in Post-menopause Women Estriol, Distal estriol, Vaginal Gel - Dyspareunia, Menopause | Phase 1 | Completed | University of Sao Paulo | 125 | 2017-06-01 | 2024-10-16 |
| Safety, Tolerability and Pharmacokinetics of Estetrol (E4) After Single and Multiple Oral Doses in Healthy Female Volunteers 5 mg E4 single-dose, 15 mg E4 single-dose, 45 mg E4 single-dose - Contraception, Menopause | Phase 1 | Completed | Estetra | 31 | 2017-01-31 | 2017-09-08 |
| Pharmacokinetics and Pharmacodynamics of 3 Dosages of Estriol After Continuous Vaginal Administration for 21 Days Estriol 0.125 mg/day, Estriol 0.250 mg/day, Estriol 0.500 mg/day - Menopause | Phase 1 | Completed | Galeno Desenvolvimento de Pesquisas Clínicas | 31 | 2016-09-23 | 2017-12-06 |
| Study Conducted to Further Understand the Elimination Pathways, Metabolite Profile and PK Profile of 14C-estetrol Estetrol - Contraception, Menopause | Phase 1 | Completed | Estetra | 6 | 2016-02-01 | 2019-02-15 |
| Evaluation of Periodontal Response to Non Surgical Therapy in Pre and Post Menopausal Women With Periodontitis scaling and root planing (srp) - Periodontitis, Menopause | Phase 1 / Phase 2 | Completed | Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre | 60 | 2015-01-01 | 2016-03-24 |
| Pharmacokinetics Study of Qing'E Pill Qing'E pill - Menopause | Phase 1 | Completed | Shanghai University of Traditional Chinese Medicine | 24 | 2013-08-01 | 2022-05-05 |
| A Study To Compare The Amount Of Premarin Components That Is Absorbed Into The Blood Of Japanese Healthy Postmenopausal Women Following Oral Administration Of Two Different Tablets Of Premarin Under Fast and Fed Conditions. Premarin reference tablet (fasted), Premarin new tablet (fasted), Premarin reference tablet (fed) - Primary Ovarian Insufficiency, Vaginitis | Phase 1 | Completed | Pfizer | 72 | 2011-10-01 | 2012-03-15 |
| Pharmacokinetics of Injectable Estradiol and Progesterone Microspheres Suspension Estradiol + Progesterone - Menopause | Phase 1 | Completed | Productos Científicos S. A. de C. V. | 30 | 2011-02-01 | 2011-10-13 |
| Comparison of Two Vaginal Tablets, Produced at Different Sites, in Postmenopausal Women With Atrophic Vaginitis estradiol, 25 mcg - Menopause, Postmenopausal Vaginal Atrophy | Phase 1 | Completed | Novo Nordisk A/S | 70 | 2010-03-01 | 2014-06-26 |
| A Pharmacokinetic Evaluation of Bioidentical Compounded Estrogen Cream and Natural Progesterone bioidentical hormone (Biest), bioidentical hormone (Vivelle-Dot) - Menopause | Phase 1 | Completed | Mayo Clinic | 40 | 2008-06-01 | 2012-01-16 |
| Study Comparing 3 New Formulations of Premarin® 0.625 mg/MPA 2.5 mg With a Reference Formulation Premarin®/MPA formulation A, Premarin®/MPA formulation B, Premarin®/MPA formulation C - Menopause | Phase 1 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 76 | 2008-02-01 | 2009-02-04 |
| Investigation of 2 Different Oral Formulations of Estradiol and Norethisterone in Healthy Women 2 mg estradiol / 1 mg norethisterone acetate (NETA) - Menopause, Healthy | Phase 1 | Completed | Novo Nordisk A/S | 44 | 2007-10-01 | 2015-03-18 |
| Study Evaluating Bazedoxifene/Conjugated Estrogens Combinations In Healthy Postmenopausal Women Bazedoxifene/Conjugated Estrogens 20 mg/0.625 mg tablet - Menopause | Phase 1 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 2007-03-01 | 2007-12-28 | |
| Pharmacokinetic Assessment of the Absorption of Estradiol in Postmenopausal Women With Atrophic Vaginitis estradiol, 10 mcg, estradiol, 25 mcg - Menopause, Postmenopausal Vaginal Atrophy | Phase 1 | Completed | Novo Nordisk A/S | 58 | 2007-01-01 | 2017-02-08 |
| Bioequivalence Study Of Bazedoxifene/Conjugated Estrogen Tablets In Postmenopausal Women bazedoxifene/conjugated estrogens - Menopause | Phase 1 | Completed | Wyeth is now a wholly owned subsidiary of Pfizer | 2006-11-01 | 2007-03-13 | |
| Bioavailability of Three Oral Formulations for Hormone Replacement Therapy in Postmenopausal Women 0.5 mg estradiol / 0.1 mg norethisterone acetate (NETA), 0.5 mg estradiol / 0.25 mg norethisterone acetate (NETA), 1.0 mg estradiol / 0.5 mg norethisterone acetate (NETA) - Menopause, Healthy | Phase 1 | Completed | Novo Nordisk A/S | 24 | 2005-03-01 | 2016-01-15 |
| Menopause and Meditation for Breast Cancer Survivors Mindfulness Meditation - Menopause | Phase 1 / Phase 2 | Completed | University of Pittsburgh | 51 | 2005-02-01 | 2014-12-03 |
| Black Cohosh Extract in Postmenopausal Breast Health Black Cohosh Extract (BCE) - Menopause, Hot Flashes | Phase 1 / Phase 2 | Completed | National Center for Complementary and Integrative Health (NCCIH) | 73 | 2003-07-01 | 2007-12-07 |
Showing 20 of 21. Sign in to see all of them.
Hot Flashes (3) · Primary Ovarian Insufficiency (2) · Breast Neoplasms (1) · Depressive Disorder, Major (1) · Dyspareunia (1) · Infertility (1) · Infertility, Female (1) · Inflammation (1) · Menopause, Premature (1) · Metrorrhagia (1) · Ovarian Dysgenesis 2 (1) · Periodontitis (1) · Plaque, Amyloid (1) · Premature Ovarian Failure 2a (1) · Premature Ovarian Failure 3 (1)
Pathological Conditions, Signs and Symptoms (5) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Genital Diseases (3) · Genital Diseases, Female (3) · Signs and Symptoms (3) · Urogenital Diseases (3) · Adnexal Diseases (2) · Endocrine System Diseases (2) · Gonadal Disorders (2) · Mental Disorders (2) · Ovarian Diseases (2) · Pathologic Processes (2) · Breast Diseases (1) · Depressive Disorder (1)
Estradiol (6) · Estetrol (2) · Estriol (2) · Estrogens, Conjugated (USP) (2) · Norethindrone Acetate (2) · bazedoxifene (2) · black cohosh root extract (2) · Mindfulness (1) · Pregnenolone (1) · Progesterone (1) · Qing'e pill (1) · Root Planing (1) · Tablets (1) · Tooth Exfoliation (1) · Urocortins (1)
Novo Nordisk A/S (4) · Wyeth is now a wholly owned subsidiary of Pfizer (3) · Estetra (2) · National Center for Complementary and Integrative Health (NCCIH) (2) · Ascendance Biomedical (1) · Galeno Desenvolvimento de Pesquisas Clínicas (1) · Mayo Clinic (1) · Panineeya Mahavidyalaya Institute of Dental Sciences & Research Centre (1) · Pfizer (1) · Productos Científicos S. A. de C. V. (1) · Shanghai University of Traditional Chinese Medicine (1) · University of Pittsburgh (1) · University of Sao Paulo (1) · University of Texas Southwestern Medical Center (1)
United States (5) · Germany (4) · Brazil (2) · Bulgaria (1) · China (1) · Japan (1) · Mexico (1) · United Kingdom (1)
Dobrin Sviranov, Prof (1) · E Scott Sills, MD PhD (1) · Edward Sauter, MD (1) · Gilberto De Nucci, MD (1) · Litza McKenzie, MBChB (1) · Marlene Freeman, MD (1) · Richa Sood, MD (1) · Roberto Bernardo, MSc (1) · Sherwood Brown, MD, PhD (1) · Susan M Cohen (1) · Suzanne Banuvar, MHSA, CCRC (1)
PMID 37619252, PMID 10782451, PMID 12050564, PMID 14583935, PMID 15189832, PMID 15804736, PMID 17262148, PMID 19170834, PMID 20423242, PMID 23384975, PMID 23848490, PMID 29486615, PMID 30796792, PMID 32195207, PMID 3425152, PMID 3793432, PMID 6880820
2004 (1), 2009 (1), 2014 (1), 2016 (1), P50AT000155 (1)