29 completed, 4 unknown, 3 terminated, 2 active not recruiting. 13 Phase 1, 8 Phase 2, 8 Phase 3, 5 Phase 4, 2 Early Phase 1.
Follow bazedoxifene: new trials by email Literature Review of bazedoxifene trials Research Report on bazedoxifene
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Novel Estrogens on Glucose and Lipids in Postmenopausal Prediabetic Women Veterans Placebo, conjugated estrogens/bazedoxifene (CE/BZA) - Menopause, Prediabetes | Phase 2 | Withdrawn | VA Office of Research and Development | 2024-04-08 | 2024-05-10 | |
| Bazedoxifene as a Concomitant Treatment of Patients With Metastatic Pancreatic Adenocarcinoma Bazedoxifene 20 mg - Pancreas Cancer | Not applicable | Unknown | Hôpital Fribourgeois | 10 | 2022-02-01 | 2022-02-25 |
| Phase IIB Trial of Bazedoxifene Plus Conjugated Estrogens Bazedoxifene and Conjugated Estrogens - Risk Reduction, Breast Cancer | Phase 2 | Active not recruiting | University of Kansas Medical Center | 120 | 2021-12-14 | 2026-10-27 |
| Pilot Study of Bazedoxifene Plus Conjugated Estrogen on Imaging and Blood Biomarkers bazedoxifene plus conjugated estrogens - Increased Risk for Development of Breast Cancer | Early Phase 1 | Completed | Carol Fabian, MD | 16 | 2021-12-02 | 2025-10-29 |
| Advancing Postmenopausal Preventive Therapy Oral bazedoxifene 20 mg / conjugated estrogens 0.45 mg, Placebo - Atherosclerosis, Cognitive Decline | Phase 2 | Active not recruiting | University of Southern California | 385 | 2021-04-13 | 2024-12-05 |
| Pilot Study of Effects of Duavee® on Imaging and Blood Biomarkers In Women With Menopausal Symptoms DUAVEE 0.45Mg-20Mg Tablet - Focus of Study is Healthy Women at Risk for Breast Cancer | Early Phase 1 | Terminated | Carol Fabian, MD | 11 | 2020-06-01 | 2021-10-29 |
| Impact of Estrogen + Estradiol Receptor Alpha Modulator Therapy on Oxidative Stress in Post-menopausal Women With and Without Sleep Apnea Duavive (0.45 estrogens mg and 20 mg bazedoxifene) - Sleep Apnea, Post Menopausal | Phase 3 | Unknown | Laval University | 36 | 2019-11-01 | 2022-04-08 |
| Bazedoxifene -Treatment for Women With Schizophrenia Bazedoxifene Acetate, Placebo - Schizophrenia, Schizophreniform Disorders | Phase 4 | Recruiting | The Alfred | 160 | 2019-10-07 | 2026-06-03 |
| Bazedoxifene Acetate as a Remyelinating Agent in Multiple Sclerosis Bazedoxifene Acetate - Multiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting | Phase 2 | Completed | Riley Bove, MD | 63 | 2019-09-10 | 2025-06-08 |
| Effects of a Tissue Selective Estrogen Complex (TSEC) on Depression and the Neural Reward System in the Perimenopause" Bazedoxifene/Conjugated Estrogen - Perimenopausal Disorder, Depression | Phase 4 | Completed | University of North Carolina, Chapel Hill | 20 | 2019-01-02 | 2022-05-10 |
| HDDO-1614 Bio Equivalence Study HDDO-1614, Bazedoxifene / Cholecalciferol - Osteoporosis | Phase 1 | Completed | Hyundai Pharmaceutical Co., LTD. | 38 | 2017-10-16 | 2018-02-26 |
| AK-R215 Pharmacokinetic Study Phase I AK-R215, Bazedoxifene 20 mg, Cholecalciferol 800IU - Healthy | Phase 1 | Unknown | Alvogen Korea | 52 | 2017-07-13 | 2017-10-25 |
| HDDO-1614 Intervention Trial Bazedoxifene 20 mg, Cholecalciferol, Bazedoxifene 20mg and Cholecalciferol - Osteoporosis | Phase 1 | Completed | Hyundai Pharmaceutical Co., LTD. | 37 | 2017-04-12 | 2017-12-11 |
| The PROMISE Study: Duavee in Women With DCIS Conjugated Estrogens/Bazedoxifene, Laboratory Biomarker Analysis, Pharmacological Study - Ductal Breast Carcinoma In Situ, Postmenopausal | Phase 2 | Completed | Northwestern University | 142 | 2017-01-01 | 2025-01-28 |
| A Phase 1 Drug Drug Interaction Clinical Trial of C1-R215 and C2-R215 in Healthy Male Volunteers Treatment B, Treatment C, Treatment BC - Healthy | Phase 1 | Unknown | Alvogen Korea | 24 | 2016-12-01 | 2016-12-29 |
| Pilot Study of the Effect of Duavee® on Benign Breast Tissue Proliferation Duavee - Breast Cancer | Phase 2 | Completed | University of Kansas Medical Center | 28 | 2016-05-01 | 2022-03-09 |
| Effectiveness of Bazedoxifene for Prevention of Glucocorticoid-induced Bone Loss in RA Patients Bazedoxifene, Calcium/Vit D - Arthritis, Rheumatoid | Phase 4 | Completed | Hanyang University | 114 | 2015-12-29 | 2020-08-12 |
| A Study of Palbociclib in Combination With Bazedoxifene in Hormone Receptor Positive Breast Cancer Palbociclib, Bazedoxifene - Breast Cancer Stage IV, Unresectable Locally Advanced Invasive Breast Cancer | Phase 1 / Phase 2 | Completed | Dana-Farber Cancer Institute | 36 | 2015-07-09 | 2022-10-24 |
| Bazedoxifene/Conjugated Estrogens (BZA/CE) Improvement of Metabolism (BIM) Bazedoxifene/Conjugated Estrogens (BZA/CE), Placebo Oral Tablet - Obesity, Glucose Homeostasis | Phase 4 | Completed | Tulane University Health Sciences Center | 17 | 2014-12-01 | 2023-06-26 |
| Post Marketing Surveillance For General Drug Use To Assess the Safety And Efficacy Profile Of Viviant In Usual Practice Viviant - Osteoporosis | Completed | Pfizer | 3430 | 2013-10-24 | 2018-12-24 |
Showing 20 of 40. Sign in to see all of them.
Osteoporosis (10) · Breast Neoplasms (4) · Osteoporosis, Postmenopausal (4) · Endometrial Hyperplasia (2) · Hot Flashes (2) · Obesity (2) · Arthritis, Rheumatoid (1) · Atherosclerosis (1) · Carcinoma, Intraductal, Noninfiltrating (1) · Cognitive Dysfunction (1) · Depression (1) · Depressive Disorder (1) · Diabetes Mellitus (1) · Mental Disorders (1) · Mood Disorders (1)
Wyeth is now a wholly owned subsidiary of Pfizer (13) · Pfizer (7) · Alvogen Korea (2) · Carol Fabian, MD (2) · Hyundai Pharmaceutical Co., LTD. (2) · University of Kansas Medical Center (2) · Dana-Farber Cancer Institute (1) · Hanyang University (1) · Hôpital Fribourgeois (1) · Instituto Palacios (1) · Laval University (1) · Northwestern University (1) · Riley Bove, MD (1) · The Alfred (1) · Tulane University Health Sciences Center (1)
United States (21) · South Korea (5) · Australia (3) · Argentina (2) · Canada (2) · Chile (2) · Denmark (2) · Finland (2) · Hungary (2) · Mexico (2) · New Zealand (2) · Norway (2) · Poland (2) · Spain (2) · Austria (1)
Carol J Fabian, MD (3) · Carol Fabian, MD (1) · Crystal E Schiller, PhD (1) · Dragana Lovre, MD (1) · Franck Mauvais-Jarvis, MD (1) · Howard N. Hodis, MD (1) · Lucie Vignot, MD (1) · Riley M Bove, MD MMSc (1) · Rinath Jelsohn, MD (1) · Sang-Heon Cho (1) · Santiago Palacios, MD (1) · Swati Kulkarni, MD (1)
PMID 27676118, PMID 19635615, PMID 20569451, PMID 20839291, PMID 23635731, PMID 24438370, PMID 28539177, PMID 31420361, PMID 34215316, PMID 36215125, PMID 37619252, PMID 37715710, PMID 37739167, PMID 38366621, PMID 39293780, PMID 40912312
1IK2CX002225-01A1 (1), P30CA060553 (1), R01AG058691 (1), R01CA249437 (1)