22 completed, 7 recruiting, 5 unknown, 4 active not recruiting. 27 Not applicable, 5 Phase 2, 2 Early Phase 1, 1 Phase 1, 1 Phase 4.
Follow Memory Loss: new trials by email Literature Review of Memory Loss trials Research Report on Memory Loss
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cholinergic Enhancement of Theta COBENFY KarXT (50/20 mg), Control - Epilepsy, Seizures | Early Phase 1 | Not yet recruiting | University of Texas Southwestern Medical Center | 50 | 2026-12-01 | 2026-09-29 |
| Evaluating a Wearable Tracking System for Family Caregivers of Persons With Dementia With Wandering Concerns Tracking/finding system - Dementia, Memory Loss | Not applicable | Withdrawn | University of Michigan | 2026-02-01 | 2026-02-23 | |
| Plans4Care: Personalized Dementia Care on Demand Plans4Care - Dementia, Dementia Alzheimer Type | Phase 2 | Not yet recruiting | Plans4Care Inc | 160 | 2025-08-30 | 2025-08-11 |
| Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia Biomarker Data Collection, MK6240 - Mild Cognitive Impairment, Alzheimer's Disease | Recruiting | GAP Innovations, PBC | 1200 | 2024-09-26 | 2026-04-15 | |
| Computerized Training of Attention and Working Memory in Post COVID-19 Patients With Cognitive Complaints RehaCom - COVID-19, Cognitive Impairment | Not applicable | Unknown | Erasmus Medical Center | 50 | 2023-12-01 | 2024-03-13 |
| Remote Game-based Exercise Program for Cognitive and Motor Function Improvement Tele-Exergame Platform, No Tele-Exergame Platform - Mild Cognitive Impairment, Dementia | Not applicable | Active not recruiting | University of California, Los Angeles | 84 | 2023-11-03 | 2026-05-15 |
| Couples Health Aging, Rhythms and Sleep Study Aging, Memory Loss | Active not recruiting | University of Utah | 340 | 2023-09-14 | 2026-02-13 | |
| Brain Health Virtual Reality Study Physical Activity, Cognitive Activity (VR), Physical and Cognitive Activity - Aging, Aging Problems | Not applicable | Active not recruiting | University of California, San Diego | 150 | 2023-08-08 | 2026-07-15 |
| A SMART Trial of Adaptive Exercises to Optimize Aerobic-Fitness Responses Moderate Intensity Continuous Training (MICT), Chair-based Stretch, High-Intensity Interval Training (HIIT) - Mild Cognitive Impairment, Alzheimer Disease | Not applicable | Recruiting | Arizona State University | 216 | 2023-06-22 | 2026-05-05 |
| Home Alone: An Intervention for People With Cognitive Impairment Who Live Alone Home Alone - Cognitive Impairment, Dementia | Not applicable | Completed | University of Minnesota | 65 | 2023-04-15 | 2025-09-19 |
| Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (active), Transcranial alternating current stimulation (tACS) (sham); Transcranial direct current stimulation (tDCS) (sham), Transcranial alternating current stimulation (tACS) (active); Transcranial direct current stimulation (tDCS) (sham) - Dementia, Memory Loss | Not applicable | Recruiting | Hebrew SeniorLife | 144 | 2023-01-24 | 2026-01-12 |
| The PorchLight Project PorchLight - Memory Loss, Alzheimer Disease | Not applicable | Active not recruiting | University of Minnesota | 342 | 2022-09-23 | 2026-11-02 |
| Effects of Multidomain Training of Health With Aging (Train-Old) Multidomain training - Sarcopenia, Memory Loss | Not applicable | Unknown | Universidad de Almeria | 80 | 2022-07-28 | 2022-08-02 |
| Identification of Patients With a High Probability of Meeting Eligibility Criteria for an Alzheimer's Disease Clinical Trial (APHELEIA) Prescreener database - Alzheimer Disease, Mild Cognitive Impairment | Completed | Global Alzheimer's Platform Foundation | 1555 | 2022-06-13 | 2025-02-05 | |
| Understanding Brain Mechanisms Involved in Autobiographical Memory high-density electroencephalography (hdEEG), Transcranial alternating current stimulation (tACS) - Mild Cognitive Impairment, Alzheimer Disease | Not applicable | Recruiting | Lucie Bréchet | 120 | 2022-04-25 | 2025-07-15 |
| A Biomarker Database to Investigate Blood-Based and Digital Biomarkers in Participants Screened for Alzheimer's Disease (Bio-Hermes) Biomarker Data Collection - Alzheimer Disease, Alzheimer Disease, Early Onset | Completed | GAP Innovations, PBC | 1002 | 2021-04-21 | 2023-02-09 | |
| A Study of HD-tDCS and Cognitive Training to Improve Cognitive Function in MCI HD-tDCS combined with CT, sham HD-tDCS combined with CT - Mild Cognitive Impairment, Memory Disorders | Not applicable | Completed | Medical College of Wisconsin | 8 | 2021-01-25 | 2026-04-23 |
| Home-based Brain Stimulation for Memory Transcranial alternating current stimulation (tACS) - Alzheimer Disease, Memory Loss | Not applicable | Completed | Hebrew SeniorLife | 20 | 2020-07-06 | 2024-06-25 |
| Exploratory Clinical Study and Validation of Blood Biomarkers for Alzheimer's Disease Alzheimer Disease, Dementia | Completed | Amoneta Diagnostics SAS | 200 | 2019-10-28 | 2025-12-19 | |
| Care to Plan: a Tailored Resource for Family Members of Persons With Dementia Care to Plan, Usual Care - Dementia, Alzheimer Disease | Not applicable | Completed | University of Minnesota | 65 | 2019-09-01 | 2023-06-02 |
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Memory Disorders (42) · Cognitive Dysfunction (20) · Alzheimer Disease (18) · Dementia (15) · Cardiovascular Diseases (2) · Epilepsy (2) · Neurocognitive Disorders (2) · Neurodegenerative Diseases (2) · Seizures (2) · Anxiety Disorders (1) · Attention Deficit Disorder with Hyperactivity (1) · Brain Diseases (1) · COVID-19 (1) · Central Nervous System Diseases (1) · Cognition Disorders (1)
Neurobehavioral Manifestations (42) · Neurologic Manifestations (42) · Pathological Conditions, Signs and Symptoms (42) · Signs and Symptoms (42) · Nervous System Diseases (41) · Mental Disorders (30) · Neurocognitive Disorders (29) · Brain Diseases (23) · Central Nervous System Diseases (23) · Cognition Disorders (19) · Tauopathies (18) · Neurodegenerative Diseases (16) · Dementia (7) · Pathologic Processes (3) · Behavior (2)
Transcranial Direct Current Stimulation (3) · Exercise (2) · Blood Specimen Collection (1) · Cognitive Training (1) · Donepezil (1) · Estradiol (1) · High-Intensity Interval Training (1) · Home Environment (1) · Isoflavones (1) · MK-6240 (1) · Pliability (1) · Range of Motion, Articular (1) · Resistance Training (1) · Restraint, Physical (1) · Scopolamine (1)
University of Minnesota (4) · Arizona State University (2) · Columbia University (2) · GAP Innovations, PBC (2) · Hebrew SeniorLife (2) · University of Texas Southwestern Medical Center (2) · Amoneta Diagnostics SAS (1) · Asan Medical Center (1) · Avraham Pharmaceuticals Ltd (1) · Cognito Therapeutics, Inc. (1) · Eisai Inc. (1) · Erasmus Medical Center (1) · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau (1) · Global Alzheimer's Platform Foundation (1) · John Wesson Ashford Jr (1)
United States (31) · Spain (3) · Canada (2) · Austria (1) · Brazil (1) · Croatia (1) · France (1) · Germany (1) · Hong Kong (1) · Netherlands (1) · Serbia (1) · South Korea (1) · Switzerland (1) · United Kingdom (1)
Bradley C Lega, MD (2) · Allan G Brigola, Ph.D. (1) · Alma Au, PhD (1) · Alvaro Pascual-Leone, Dr. (1) · Alvaro Pascual-Leone, MD; PhD (1) · Anita Murthy (1) · Brad Manor, PhD (1) · Catherine V Piersol, PhD, OTR/L,FAOTA, FNAP (1) · Christiane Reitz, MD, PhD (1) · Colleen M Peterson, PhD (1) · David E Warren, PhD (1) · David W. Coon, PhD (1) · Eric Jutkowitz, PhD (1) · Evan R Hempel (1)
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R01AG013241 (1), R01AG023091 (1), R01AG033288 (1), R01AG055526 (1), R01AG058417 (1), R01AG064614 (1), R01AG076708 (1), R01NS125250 (1), R21AG060419 (1), R42AG058336 (1), R44AG041667 (1), R44AG067909 (1), R44AG084365 (1), U24AG056270 (1)