2 enrolling by invitation, 1 not yet recruiting, 1 recruiting. 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 1 | Not yet recruiting 1 |
| Phase 2 | 1 | Enrolling by invitation 1 |
Follow MK-6240: new trials by email Literature Review of MK-6240 trials Research Report on MK-6240
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and Tau Neuronavigation-guided single-element focused ultrasound transducer, Lumason, Magnetic Resonance Imaging (MRI) with or without gadolinium contrast agents - Alzheimer Disease, Early Onset | Phase 1 | Not yet recruiting | Columbia University | 6 | 2027-08-01 | 2026-05-13 |
| Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia Biomarker Data Collection, MK6240 - Mild Cognitive Impairment, Alzheimer's Disease | Recruiting | GAP Innovations, PBC | 1200 | 2024-09-26 | 2026-04-15 | |
| Alzheimer's Disease Neuroimaging Initiative 4 Neuraceq, Amyvid, Tauvid - Mild Cognitive Impairment, Alzheimer Disease | Enrolling by invitation | University of Southern California | 1500 | 2023-06-09 | 2026-09-29 | |
| Tau PET Imaging in the Northern Manhattan Study of Metabolism and Mind. 18F-MK6240 injection - Diabetes Mellitus, Type 2, Pre-diabetes | Phase 2 | Enrolling by invitation | Columbia University | 600 | 2018-07-24 | 2025-05-06 |
Alzheimer Disease (3) · Cognitive Dysfunction (2) · Pick Disease of the Brain (2) · Cognition Disorders (1) · Dementia (1) · Diabetes Mellitus (1) · Diabetes Mellitus, Type 2 (1) · Glucose Intolerance (1) · Hyperglycemia (1) · Memory Disorders (1) · Plaque, Amyloid (1)
Columbia University (2) · GAP Innovations, PBC (1) · University of Southern California (1)
United States (4) · Canada (2) · United Kingdom (1)
Grace McIlvain, PhD (1) · Jose A. Luchsinger, MD (1) · Michael Weiner, MD (1) · Paul Aisen, MD (1) · Ronald Petersen, MD, PHD (1)
R01AG050440 (1), R01AG055299 (1), RF1AG051556 (1), U19AG024904 (1)