17 completed, 2 terminated, 2 unknown, 1 active not recruiting. 10 Not applicable, 6 Phase 2, 3 Phase 3, 3 Phase 4, 2 Early Phase 1.
Follow Isoflavones: new trials by email Literature Review of Isoflavones trials Research Report on Isoflavones
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effects of Menopausal Status, Isoflavone Supplementation and Training on Cardiometabolic Function Women Red Clover Isoflavone Supplementation, Supervised exercise training, Placebo Supplementation - Menopause, Exercise Adaptation | Not applicable | Not yet recruiting | University of Copenhagen | 60 | 2027-10-15 | 2026-10-16 |
| Polyphenol Metabolism and Personalized Nutrition in Menopause (PolyPause). Capsules containing plant extracts, including resveratrol, ellagic acid and isoflavones, Consumption of placebo - Menopause Related Conditions, Cardiovascular Risk | Not applicable | Active not recruiting | National Research Council, Spain | 90 | 2024-01-15 | 2025-09-19 |
| Effects of Physical Training and Isoflavone Supplementation On Pelvic Floor in Women in the Postmenopausal Period Exercise, isoflavone, placebo - Pelvic Floor | Phase 4 | Completed | Federal University of Uberlandia | 22 | 2016-09-01 | 2017-05-30 |
| Effects of Isoflavone Combined With Astaxanthin on Skin Aging Isoflavone, Astaxanthin, Placebo - Ageing, Photo-aging | Not applicable | Completed | Seoul National University Hospital | 90 | 2015-03-01 | 2016-06-14 |
| Effect of Isoflavone Supplementation Associated With Physical Exercise in the Health Parameters of Postmenopausal Women exercise, isoflavone, Placebo - Bloodpressure | Not applicable | Completed | Federal University of Uberlandia | 32 | 2015-02-01 | 2019-02-20 |
| Soy Supplementation and Gestational Diabetes Soy Group (Soy Protein + Isoflavones), Control Group (Minimize Soy Intake) - Gestational Diabetes | Early Phase 1 | Completed | University of Massachusetts, Boston | 40 | 2013-01-01 | 2016-10-27 |
| Effects of Combining Cocoa and Soy in Type 2 Diabetes Soy protein, Isoflavones, Cocoa - Type 2 Diabetes, Dietary Intervention | Not applicable | Completed | Hull University Teaching Hospitals NHS Trust | 84 | 2011-10-01 | 2019-07-15 |
| Effect of Lycopene and Isoflavones on Glucose Metabolism Randomized pills either containing combination of lycopene and isoflavones (dietary supplements) or Placebo to be taken for 12 weeks, Screening, OGTT - Metabolic Syndrome, Diabetes Mellitus, Non-Insulin-Dependent | Not applicable | Withdrawn | The University of Texas Medical Branch, Galveston | 2010-09-01 | 2015-06-26 | |
| Effects of the Concentrated Extract of Soy on Coagulation Factors After Menopause Isoflavone, Placebo - Menopause | Phase 3 | Unknown | Federal University of São Paulo | 84 | 2009-08-01 | 2009-06-22 |
| The Effects of Isoflavone and Estrogen in Sex Response in Climacteric Women estradiol, isoflavone, Placebo - Postmenopausal Symptoms | Phase 3 | Unknown | Federal University of São Paulo | 60 | 2009-05-01 | 2009-05-20 |
| Phytoestrogen Supplementation in Postmenopausal Women phytoestrogens - Low Serum Lipid Levels | Phase 4 | Completed | American Medical Academy, Serbia | 74 | 2008-09-01 | 2011-12-29 |
| The Effects of Soy Protein and Isoflavones on Glycemic Control, Insulin Sensitivity and Cardiovascular Risk Factors soy protein, isoflavones, milk protein - Diabetes, Cardiovascular Risk | Not applicable | Completed | Chinese University of Hong Kong | 2007-10-01 | 2009-03-06 | |
| Vitamin D and Soy Supplements in Treating Patients With Recurrent Prostate Cancer Vitamin D, soy - Prostate Cancer | Phase 2 | Completed | Wake Forest University Health Sciences | 26 | 2007-04-01 | 2018-11-21 |
| Soy Protein/Effexor Hormone Therapy for Prostate Cancer oral soy protein/isoflavones powder, Venlafaxine, Placebo Powder - Hot Flashes, Prostate Cancer | Phase 3 | Terminated | Wake Forest University Health Sciences | 120 | 2007-02-01 | 2021-09-28 |
| Effect of Revival Soy on Fibromyalgia Pain Soy, Placebo - Fibromyalgia | Not applicable | Completed | Mayo Clinic | 50 | 2006-05-01 | 2012-01-06 |
| Effects of Isoflavone in Patients With Watchful Waiting Benign Prostate Hyperplasia isoflavones (Soylife 25), placebo - Benign Prostate Hyperplasia | Not applicable | Completed | Chinese University of Hong Kong | 176 | 2006-02-01 | 2009-03-13 |
| Genistein and Interleukin-2 in Treating Patients With Metastatic Melanoma or Kidney Cancer High-dose interleukin-2, genistein - Kidney Cancer, Melanoma (Skin) | Early Phase 1 | Completed | Northwestern University | 15 | 2005-11-01 | 2015-04-10 |
| Effect of Soy on Cognition and Hot Flashes in Men With Prostate Cancer Undergoing Testosterone Suppression Therapy Isoflavone, Placebos - Hot Flashes | Phase 4 | Completed | Johns Hopkins University | 39 | 2005-06-01 | 2017-10-13 |
| Postmenopausal Facial Skin After Estradiol and Genistein Topical Treatment isoflavone, Estradiol - Atrophy | Phase 2 | Completed | Federal University of São Paulo | 30 | 2004-07-01 | 2012-03-14 |
| Soy Isoflavones and Breast Cancer Risk Reduction isoflavones, carbohydrate - Breast Cancer | Phase 2 | Completed | The University of Texas Medical Branch, Galveston | 197 | 2004-04-01 | 2024-05-16 |
Showing 20 of 24. Sign in to see all of them.
Prostatic Neoplasms (4) · Breast Neoplasms (3) · Hot Flashes (3) · Diabetes Mellitus, Type 2 (2) · Motor Activity (2) · Atrophy (1) · Breast Carcinoma In Situ (1) · Carcinoma, Intraductal, Noninfiltrating (1) · Carcinoma, Renal Cell (1) · Diabetes Mellitus (1) · Diabetes, Gestational (1) · Endotoxemia (1) · Fibromyalgia (1) · Insulin Resistance (1) · Kidney Neoplasms (1)
Federal University of São Paulo (3) · Chinese University of Hong Kong (2) · Federal University of Uberlandia (2) · The University of Texas Medical Branch, Galveston (2) · Wake Forest University Health Sciences (2) · Alliance for Clinical Trials in Oncology (1) · American Medical Academy, Serbia (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · Hull University Teaching Hospitals NHS Trust (1) · Johns Hopkins University (1) · Mayo Clinic (1) · National Center for Complementary and Integrative Health (NCCIH) (1) · National Research Council, Spain (1) · Northwestern University (1) · Seoul National University Hospital (1)
United States (12) · Brazil (4) · Denmark (1) · Hong Kong (1) · Serbia (1) · South Korea (1) · Spain (1) · United Kingdom (1)
Charles J. Rosser, MD (1) · Dietlind L. Wahner-Roedler, M.D. (1) · Gini F. Fleming, MD (1) · Guilherme Puga, PhD (1) · Jin Ho Chung, MD, PhD (1) · K.C. Balaji, MD (1) · Lee-Jane W Lu, Ph.D. (1) · Ling Shi, PhD (1) · Mara Vitolins, DrPH, RD (1) · Marisa T Patriarca, MD, PhD (1) · Mauro A Aidar, M.D., PhD (1) · Mauro A Aidar, M.D., PhD. (1) · Milan Terzic, Prof. dr (1) · Nagi B. Kumar, PhD, RD, FADA (1)
PMID 11580731, PMID 18471323, PMID 18990724, PMID 19918248, PMID 20046616, PMID 22268969, PMID 23044556, PMID 24081940, PMID 24378766, PMID 24659208, PMID 25372005, PMID 28508697, PMID 29183775, PMID 30176281, PMID 31535213, PMID 36513449
1UL1RR029876-01 (1), M01RR000073 (1), P30CA012197 (1), R01CA095545 (1), U10CA076001 (1), U10CA081851 (1)