22 completed, 10 unknown, 4 recruiting, 3 not yet recruiting. 21 Not applicable, 8 Phase 4, 6 Phase 3, 3 Phase 2, 1 Phase 1.
Follow Mastodynia: new trials by email Literature Review of Mastodynia trials Research Report on Mastodynia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Hormones, Outcomes, and Pain Pathways in Exercise Study Interventional Sports bra - Breast Pain, Mastalgia | Phase 1 | Recruiting | University of Houston | 140 | 2026-05-17 | 2026-06-02 |
| Comparison of the Postoperative Analgesic Efficacy of SAP and SPSIP Blocks in Patients Undergoing Mammoplasty Serratus Anterior Plane Block, Serratus Posterior Superior Intercostal Plane Block - Postoperative Pain, Postsurgical Pain | Not applicable | Not yet recruiting | Abant Izzet Baysal University | 60 | 2026-02-01 | 2026-01-13 |
| ATUSA Ultrasound Diagnostic Imaging for Breast Lesions Evaluation (AUDIBLE) - iSono Health ATUSA 3D Automated Breast Ultrasound System - Breast Cancer, Benign Breast Condition | Recruiting | iSono Health, Inc. | 800 | 2025-12-16 | 2026-09-17 | |
| Local Treatment of Breast Pain Based on the Daily Use of a Topical Gel inositol - Mastalgia | Not applicable | Recruiting | Lo.Li.Pharma s.r.l | 50 | 2025-09-11 | 2026-02-13 |
| External Mastalgia-oil Versus Placebo in Premenopausal Women With Severe Mastalgia mastalgia-oil, Mastalgia-oil placebo - Mastalgia | Phase 3 | Recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 190 | 2025-06-08 | 2026-02-02 |
| External Mastalgia-oil Versus Oral Tamoxifen in Premenopausal Women with Severe Mastalgia mastalgia-oil, tamoxifen placebo, mastalgia-oil placebo, tamoxifen - Mastalgia | Phase 3 | Not yet recruiting | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 456 | 2025-01-16 | 2024-11-29 |
| Study on the Effects of Acupuncture in Patients with Cyclic Mastalgia sham acupuncture, acupuncture - Breast Pain | Not applicable | Not yet recruiting | Chuan Yu | 66 | 2024-12-01 | 2024-12-03 |
| Acupuncture for Breast Pain Acupuncture, Sham acupuncture - Acupuncture, Mastodynia | Not applicable | Unknown | Guang'anmen Hospital of China Academy of Chinese Medical Sciences | 60 | 2023-03-01 | 2023-02-28 |
| Pattern of Clinical Presentation of Different Breast Disease in Surgical Opd at BPKIHS Breast Disease, Breast Neoplasms | Completed | B.P. Koirala Institute of Health Sciences | 1023 | 2022-08-01 | 2023-09-06 | |
| Effectiveness of Acupuncture for Cyclical Mastalgia （CM） MA group, SA group - Mastalgia | Not applicable | Unknown | Pinggu Hospital of Beijing Traditional Chinese Medicine Hospital | 108 | 2022-07-20 | 2024-04-09 |
| Comparing Sports Bra Design in Full Busted Women Conventional bra, Bounceless bra, Shefit bra - Breast Pain, Mastalgia | Not applicable | Completed | University of Houston | 33 | 2022-06-20 | 2023-11-30 |
| Predicting Chronic Pain Following Breast Surgery Chronic Pain, Opioid Use | Unknown | University of California, San Diego | 500 | 2021-07-19 | 2023-07-27 | |
| Omega-3 Fatty Acids Plus Vitamin E Cosupplementation Versus Vitamin E in Fibrocystic Breast Patient Omega 3 fatty acid, VitaE - Mastalgia | Phase 4 | Unknown | Cairo University | 120 | 2021-01-01 | 2021-01-05 |
| Evaluation of Sleep Quality, Nutrition, Anxiety and Depression in Mastalgia Hospital anxiety and depression scale, Pittsburgh Sleep Quality Index, Nutritional Status Questionnaire - Mastodynia | Completed | Nigde Omer Halisdemir University | 217 | 2021-01-01 | 2022-01-04 | |
| The Impact of Pecs Blocks on Postmastectomy Pain Syndrome Pecs block, no Pecs block - Pain Syndrome, Pain, Postoperative | Not applicable | Completed | Aretaieion University Hospital | 64 | 2020-08-01 | 2023-02-08 |
| A New Treatment Option for Mastalgia TENS - Mastalgia | Not applicable | Completed | Ankara University | 93 | 2020-02-01 | 2023-12-13 |
| e-Nature VR: Evaluation of the Impact of Virtual Reality During Breast Biopsy Nature virtual reality video - Pain, Breast Pain | Not applicable | Terminated | Hospital Israelita Albert Einstein | 24 | 2019-07-31 | 2022-05-31 |
| Serratus and Parasternal Infrapectoral Block for Breast Surgery. Unilateral serratus plane block, Unilateral parasternal infrapectoral block - Breast Pain, Post-Op Complication | Not applicable | Unknown | Western University, Canada | 120 | 2019-07-01 | 2024-03-07 |
| Evaluation of an Educational Intervention for Women With Breast Pain Breast Pain video, Semi-structure interviews - Breast Pain, Mastalgia | Not applicable | Unknown | Royal Marsden NHS Foundation Trust | 15 | 2019-05-31 | 2019-05-03 |
| Ropivacaine 0,2% Plus Dexamethasone Versus Ropivacaine 0,2% Plus Placebo in Modified Pectoral Block Dexamethasone, Placebo, Ropivacaine Injection [Naropin] - Effect of Drugs, Breast Pain | Phase 4 | Unknown | Medical University Innsbruck | 60 | 2019-02-01 | 2020-03-12 |
Showing 20 of 43. Sign in to see all of them.
Breast Neoplasms (9) · Pain, Postoperative (4) · Anxiety Disorders (3) · Breast Diseases (3) · Fibroadenoma (3) · Fibrocystic Breast Disease (3) · Pain (3) · Back Pain (2) · Body Weight (2) · Chest Pain (2) · Chronic Pain (2) · Cystic Fibrosis (2) · Low Back Pain (2) · Motor Activity (2)
Neurologic Manifestations (43) · Pathological Conditions, Signs and Symptoms (43) · Signs and Symptoms (43) · Pain (40) · Skin Diseases (14) · Skin and Connective Tissue Diseases (14) · Breast Diseases (11) · Neoplasms (11) · Neoplasms by Site (9) · Pathologic Processes (9) · Nervous System Diseases (5) · Behavior (4) · Mental Disorders (4) · Postoperative Complications (4) · Neoplasms by Histologic Type (3)
Acupuncture Therapy (3) · Tamoxifen (2) · Acetaminophen (1) · Bupivacaine (1) · Cryosurgery (1) · Danazol (1) · Dexamethasone (1) · Diclofenac (1) · Fatty Acids, Omega-3 (1) · High-Energy Shock Waves (1) · Ibuprofen (1) · Injections (1) · Iodides (1) · Lidocaine (1) · Lidoderm (1)
Duke University (2) · Mayo Clinic (2) · Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University (2) · University of California, San Diego (2) · University of Houston (2) · ASCEND Therapeutics (1) · Abant Izzet Baysal University (1) · Ankara University (1) · Aretaieion University Hospital (1) · B.P. Koirala Institute of Health Sciences (1) · Bionorica SE (1) · Biosearch S.A. (1) · Cairo University (1) · Chuan Yu (1) · Emory University (1)
United States (17) · China (4) · Turkey (Türkiye) (4) · Egypt (2) · Spain (2) · United Kingdom (2) · Austria (1) · Brazil (1) · Canada (1) · Cyprus (1) · Finland (1) · Germany (1) · Greece (1) · India (1) · Italy (1)
Abhijit Biswas, MD (1) · Ahmed Salman (1) · Andrzej Witek, MD PhD Prof. (1) · Bin Shen (1) · Brian M Ilfeld, M.D., M.S. (1) · Cemal Kaya, M.D. (1) · Chang Gong, Prof (1) · Christopher M Runyan, MD (1) · Colleen K. Lambertz, MSN, FNP (1) · Emma Burnett, MRes (1) · Hannes Herold, Dr. med. (1) · Joanna Scurr, PhD (1)
PMID 22963023, PMID 24402166, PMID 24874898, PMID 29794944, PMID 30063656, PMID 30829925, PMID 32987448, PMID 36401325
P20NR016605 (1), R01AR084021 (1), R44CA291498 (1)