6 not yet recruiting, 3 completed, 2 recruiting, 1 active not recruiting. 2 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Not yet recruiting 1, Unknown 1 |
| Phase 4 | 1 | Not yet recruiting 1 |
Follow MACE: new trials by email Literature Review of MACE trials Research Report on MACE
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Micro-nanoplastic Exposure and Coronary Microcirculatory Dysfunction as Well as Cardiovascular Outcomes micro-nanoplastic examination, Microvascular Function Examination - Coronary Microvascular Dysfunction (CMD), Microplastic Exposure | Not yet recruiting | Beijing Anzhen Hospital | 184 | 2027-01-01 | 2026-08-21 | |
| MACE and BTK Inhibitors ibrutinib, Acalabrutinib, Zanubrutinib - Hematologic Cancer, MACE | Phase 4 | Not yet recruiting | University Hospital, Caen | 10000 | 2026-12-01 | 2026-11-06 |
| throMboembolic Risk Associated To High atrIal Fibrillation riSk AI_MATHIAS - MACE, Atrial Fibrillation (AF) | Not yet recruiting | Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina | 1000 | 2026-07-06 | 2026-03-02 | |
| Steroid Treatment to Prevent Thoracic Endovascular Aortic Repair Postimplantation Syndrome Methylprednisolone (MP), Placebo (saline) - Postimplantation Syndrome, Myocardial Injury | Not applicable | Not yet recruiting | University of Belgrade | 174 | 2026-01-01 | 2026-01-12 |
| Prospective Observational Cohort Study on Impact of Frailty on Risk Prediction, Treatment Strategies, and Short-Term Outcomes in Patients With Acute Coronary Syndrome Frailty, ACS (Acute Coronary Syndrome) | Not yet recruiting | Assiut University | 645 | 2025-12-01 | 2025-09-24 | |
| Tezspire Cardiac Events PASS Tezepelumab - Cardiovascular Events, MACE | Recruiting | AstraZeneca | 16640 | 2025-09-15 | 2026-09-18 | |
| "Short-term Outcome in STEMI Patients Undergoing Primary PCI: A Comparative Study Between Rural and Urban Communities at Assiut University." Primary Percutaneous Coronary Intervention (PPCI) - MACE, In STEMI | Not yet recruiting | Assiut University | 162 | 2025-08-15 | 2025-08-22 | |
| AI-Based Risk Factor Analysis and Prediction Model of MACE in Elderly Hip Fracture Patients Postoperatively Hip Fracture, MACE | Active not recruiting | Beijing Anzhen Hospital | 600 | 2025-07-01 | 2026-07-16 | |
| Real-World Cohort Study of Cardiopulmonary Function in Chinese Patients With Cardiovascular Disease: CPET Evaluation and Five-Year Prognostic Follow-Up Based on a Multicenter Structured Data Platform MACE, Cardiac Death | Enrolling by invitation | Guangdong Provincial People's Hospital | 200000 | 2025-02-01 | 2026-04-29 | |
| Do QT-Prolonging Drugs Cause Major Adverse Cardiac Events in Hospitalized Adults? Acquired Long QT, Ventricular Arrhythmias | Recruiting | St. Joseph's Healthcare Hamilton | 990000 | 2025-02-01 | 2026-01-28 | |
| Primary Prevention Long-term Registry Study in OSA and Hypertension. Survival Analysis 2010-2022 Positive airway pressure (PAP) - Hypertension, OSA - Obstructive Sleep Apnea | Completed | Vastra Gotaland Region | 148467 | 2025-01-01 | 2025-05-23 | |
| Discharge Planning Program for Post CABG Patients Nurse led discharge planning program - Coronary Artery Bypass Graft Surgery, Mace | Not applicable | Unknown | University of Jordan | 174 | 2020-08-01 | 2024-03-19 |
| ROOBY Trial Follow-up Extension All Cause Mortality, MACE | Completed | VA Office of Research and Development | 2203 | 2013-10-01 | 2019-06-07 | |
| The Prognostic Significance of a Fragmented QRS Complex After Primary Percutaneous Coronary Intervention primary pcı - Fragmented QRS, Primary PCI | Completed | Bursa Postgraduate Hospital | 85 | 2008-11-01 | 2010-06-04 |
Cardiovascular Diseases (2) · Coronary Artery Disease (2) · Stroke (2) · Acute Coronary Syndrome (1) · Atrial Fibrillation (1) · Death (1) · Frailty (1) · Heart Diseases (1) · Heart Failure (1) · Hematologic Neoplasms (1) · Hip Fractures (1) · Hypertension (1) · Long QT Syndrome (1) · Myocardial Ischemia (1) · Sleep Apnea, Obstructive (1)
Vascular Diseases (6) · Cardiovascular Diseases (5) · Heart Diseases (4) · Nervous System Diseases (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Arrhythmias, Cardiac (2) · Arterial Occlusive Diseases (2) · Arteriosclerosis (2) · Brain Diseases (2) · Central Nervous System Diseases (2) · Cerebrovascular Disorders (2) · Coronary Disease (2) · Myocardial Ischemia (2) · Apnea (1)
Methylprednisolone (1) · Sodium Chloride (1) · acalabrutinib (1) · ibrutinib (1) · tezepelumab (1) · zanubrutinib (1)
Assiut University (2) · Beijing Anzhen Hospital (2) · AstraZeneca (1) · Bursa Postgraduate Hospital (1) · Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina (1) · Guangdong Provincial People's Hospital (1) · St. Joseph's Healthcare Hamilton (1) · University Hospital, Caen (1) · University of Belgrade (1) · University of Jordan (1) · VA Office of Research and Development (1) · Vastra Gotaland Region (1)
China (2) · France (2) · United States (2) · Canada (1) · Denmark (1) · Germany (1) · Jordan (1) · Serbia (1) · Spain (1) · Sweden (1) · Turkey (Türkiye) (1)
Anne M Holbrook (1) · Annie Laurie Shroyer, PhD MHSA (1) · Josep Clua-Espuny, PhD (1) · Peter Egger (1) · Sven Svedmyr, MD (1)
PMID 10027821, PMID 21344317, PMID 28813218, PMID 30115967, PMID 31891317, PMID 33546615, PMID 35171210, PMID 35998199, PMID 38373864, PMID 39857703