35 completed, 11 unknown, 6 terminated, 4 recruiting. 65 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Early Phase 1 | 65 | Completed 35, Unknown 11, Terminated 6, Recruiting 4, Active not recruiting 3, Withdrawn 3, Enrolling by invitation 2, Not yet recruiting 1 |
Follow Lung Diseases, Obstructive: new trials by email Literature Review of Lung Diseases, Obstructive trials Research Report on Lung Diseases, Obstructive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Treatment of Chronic Obstructive Pulmonary Disease (COPD) by REGEND007 Cell Therapy REGEND007 - Chronic Obstructive Pulmonary Disease (COPD) | Early Phase 1 | Recruiting | Regend Therapeutics | 12 | 2026-03-19 | 2026-03-23 |
| Treatment of Pediatric Bronchiolitis Obliterans by Airway Basal Stem Cells Airway Basal Stem Cells - Pediatric Bronchiolitis Obliterans | Early Phase 1 | Recruiting | Regend Therapeutics | 12 | 2025-11-11 | 2026-01-14 |
| Treatment of Refractory cGVHD by Donor-derived Treg Cell Injection Combined With Recombinant Human Interleukin-2 Donor-derived Treg cell injection combined with interleukin 2 - cGVHD | Early Phase 1 | Recruiting | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 18 | 2025-06-14 | 2025-09-30 |
| Effectiveness of 1st Rib Mobilization and Scalene Muscles Muscle Energy Technique Among Patients With Asthma First Rib Mobilization + Respiratory Physiotherapy, Scalene Muscle Energy Technique (MET) + Respiratory Physiotherapy - Asthma | Early Phase 1 | Active not recruiting | Superior University | 47 | 2025-03-04 | 2025-06-25 |
| Observation Study on the Efficacy of Yiqi Gubiao Pill in the Treatment of Chronic Obstructive Pulmonary Disease Secondary to Active Pulmonary Tuberculosis Yiqi Gubiao pill, Yiqi Gubiao Pill placebo - Tuberculosis-related Obstructive Pulmonary Disease | Early Phase 1 | Not yet recruiting | Fourth Affiliated Hospital of Xinjiang Medical University | 74 | 2024-11-30 | 2024-11-06 |
| Airway Bypass - Safety and Feasibility Study Airway Bypass - Emphysema or COPD | Early Phase 1 | Unknown | Zoar Engelman | 10 | 2024-01-26 | 2024-02-08 |
| Timely Administration of IV Magnesium Sulfate in Patients With a Moderate Asthma Exacerbation Magnesium Sulfate within the first hour, No Magnesium sulfate within the first hour - Asthma in Children, Asthma Attack | Early Phase 1 | Recruiting | University of Oklahoma | 100 | 2023-11-30 | 2024-12-06 |
| Development of Methods for Effective Treatment and Improvement of Common Somatic Diseases in Children The use of a combination of microelements and vitamins against the background of physiotherapy - Respiratory Diseases, Congenital Heart Defects | Early Phase 1 | Enrolling by invitation | Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan | 600 | 2023-11-08 | 2026-09-03 |
| The Bronchiolitis in Hospitalized Infants Study Dexamethasone Oral - Bronchiolitis | Early Phase 1 | Withdrawn | IDeA States Pediatric Clinical Trials Network | 2023-10-09 | 2023-09-14 | |
| Short Acting Agents Vs Long Acting in Frequent Excerbator COPD Patients SABA SAMA ICS Vs LABA LAMA ICs - Copd | Early Phase 1 | Unknown | Assiut University | 80 | 2023-02-20 | 2023-03-01 |
| Mitochondrial Derived Reactive Oxygen Species on Cardiovascular Health in Chronic Obstructive Pulmonary Disease (COPD) MitoQ, Placebo - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Terminated | Virginia Commonwealth University | 4 | 2023-02-16 | 2025-02-27 |
| Electronic Cigarette-derived Oxidants and Cardiopulmonary Effects NJOY e-cigarette - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Active not recruiting | Milton S. Hershey Medical Center | 30 | 2022-11-22 | 2025-10-27 |
| Comparison of 3% Normal Saline Nebulization Versus Steroid Nebulization in the Treatment of Bronchiolitis 3% normal saline, steroid(beclomethasone dipropionate 400 μg/day) and salbutamol with 0.9% normal saline - Acute Bronchiolitis | Early Phase 1 | Completed | Mardan Medical Complex | 60 | 2022-11-15 | 2023-11-21 |
| Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive Pulmonary Disease (COPD) LAIV - COPD | Early Phase 1 | Completed | University of North Carolina, Chapel Hill | 24 | 2022-10-03 | 2026-06-23 |
| Effect of NMES on Quadriceps Muscle Strength and Endurance in Patients With COPD Neuromuscular Electrical Nerve Stimulation, Usual Physiotherapy treatment (Chest Physiotherapy and mobility) - Chronic Obstructive Pulmonary Disease Moderate, Chronic Obstructive Pulmonary Disease Severe | Early Phase 1 | Unknown | Randall Debattista | 140 | 2022-10-01 | 2022-09-14 |
| Therapeutic Effects of Jing Si Herbal Tea for COPD Jing Si herbal tea (JSHT), Placebo - Airway Disease | Early Phase 1 | Unknown | Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation | 120 | 2022-01-01 | 2024-09-05 |
| A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence Quality-of-Life Assessment, Questionnaire Administration, Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine - Chronic Obstructive Pulmonary Disease, Lung Non-Small Cell Carcinoma | Early Phase 1 | Completed | Roswell Park Cancer Institute | 20 | 2021-11-22 | 2026-03-17 |
| The Effect of Inhaled Nitric Oxide on Deadspace in COPD Nitric Oxide, Placebo - Chronic Obstructive Pulmonary Disease | Early Phase 1 | Completed | Dr. Denis O'Donnell | 13 | 2021-09-01 | 2024-04-03 |
| Effectiveness of a Mobile Health Intervention in Improving the Technique of Inhaled Medications Among Children With Asthma BreatheSuite - Asthma, Asthma in Children | Early Phase 1 | Completed | Memorial University of Newfoundland | 30 | 2021-01-01 | 2022-04-08 |
| Treatment of CRF With Syndrome Differentiation of TCM Placebo, Traditional Chinese medicine prescription - Chronic Respiratory Failure | Early Phase 1 | Unknown | Henan University of Traditional Chinese Medicine | 120 | 2021-01-01 | 2021-01-06 |
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Pulmonary Disease, Chronic Obstructive (34) · Asthma (25) · Bronchiolitis Obliterans Syndrome (6) · Bronchiolitis Obliterans (3) · Bronchiolitis (2) · Dyspnea (2) · Emphysema (2) · Hypertension, Pulmonary (2) · Lung Diseases (2) · Lung Diseases, Interstitial (2) · Lung Neoplasms (2) · Smoking (2) · Angina Pectoris (1) · Asbestosis (1) · Blister (1)
Respiratory Tract Diseases (64) · Lung Diseases (63) · Bronchial Diseases (37) · Pathological Conditions, Signs and Symptoms (37) · Chronic Disease (35) · Disease Attributes (35) · Pathologic Processes (35) · Immune System Diseases (31) · Hypersensitivity, Immediate (25) · Respiratory Hypersensitivity (25) · Hypersensitivity (24) · Bronchitis (11) · Bronchiolitis (8) · Infections (8)
montelukast (4) · Mannitol (2) · Standard of Care (2) · Albuterol (1) · Antigens, Dermatophagoides (1) · Azithromycin (1) · Budesonide (1) · CIMAvax EGF (1) · Curcumin (1) · Cycloserine (1) · Dexamethasone (1) · Dobutamine (1) · FluMist (1) · Fluticasone-Salmeterol Drug Combination (1) · Gadolinium (1)
Roxane Laboratories (4) · AstraZeneca (2) · Hamilton Health Sciences Corporation (2) · Janssen Research & Development, LLC (2) · Regend Therapeutics (2) · Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine (2) · University of North Carolina, Chapel Hill (2) · Virginia Commonwealth University (2) · Assiut University (1) · Bellerophon (1) · Black Tie Medical, Inc. (1) · Columbia University (1) · Col·legi de Farmacèutics de la Província de Barcelona (1) · Dr. Denis O'Donnell (1) · Emily DiMango, MD (1)
United States (33) · Canada (7) · United Kingdom (7) · China (6) · Germany (3) · Belgium (2) · France (2) · Italy (2) · Netherlands (2) · Pakistan (2) · Spain (2) · Austria (1) · Denmark (1) · Egypt (1) · Georgia (1)
Alan K Copa, PharmD (4) · Gail Gauvreau, PhD (2) · Paul O'Byrne, MD (2) · Ashika Ahmed, MD (1) · Ashley Deschamp, MD,MS (1) · Cecil Charles, PhD (1) · Chou-Chin Lan, MD (1) · Christine A Sorkness, Pharm.D. (1) · David Halpin, MD (1) · Denis E O'Donnell, MD (1) · Diego Castillo, MD (1) · Dr. Tonio Agius, Physiotherapist (1) · Elizabeth Oelsner, MD, MPH (1) · Emily DiMango, MD (1)
PMID 12359244, PMID 21687919, PMID 26310525, PMID 27486204, PMID 27978840, PMID 31332045, PMID 32883677, PMID 35584850, PMID 35691614, PMID 35762891, PMID 36572534, PMID 37020840, PMID 38249987, PMID 38798038, PMID 40455920, PMID 41132532
P01HL158507 (1), R01HL064368 (1), R01HL122424 (1), R01HL135235 (1), R01HL150081 (1), R01HL152436 (1), R61AT009989 (1), UL1TR001412 (1)