62 completed, 6 terminated, 2 active not recruiting, 2 recruiting. 28 Phase 4, 14 Phase 3, 12 Phase 1, 9 Phase 2, 4 Not applicable.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| How Healthy Adults Respond to the Nasal Flu Vaccine FluMist (Live Attenuated Influenza Vaccine) - Mucosal Immune Response to Influenza Vaccination | Phase 4 | Not yet recruiting | University of Alabama at Birmingham | 20 | 2026-12-01 | 2026-10-13 |
| Woodsmoke Exposure, Influenza Infection, and Nasal Immunity LAIV nasal vaccine is chosen as a model viral infection, Wood smoke, Placebo for LAIV nasal vaccine is chosen as a model viral infection - Smoke Exposure, Influenza | Phase 4 | Recruiting | University of North Carolina, Chapel Hill | 112 | 2025-09-26 | 2026-04-30 |
| Characterizing the Human Airway Immune Response to FluMist Vaccination FluMist, inactivated influenza vaccine, bronchoscopy - Healthy Young Adults, Influenza Vaccines | Phase 4 | Recruiting | Washington University School of Medicine | 30 | 2025-09-09 | 2025-09-17 |
| Vaccine Pandemic Preparedness Through Airway Immunology Characterization Vaxigripetra, Flumist - Influenza, Human | Early Phase 1 | Active not recruiting | Copenhagen Respiratory Research | 60 | 2025-05-19 | 2026-03-25 |
| Revealing Protective Immunity to Influenza Using Systems Immunology Live Attenuated Influenza Vaccine - Influenza | Phase 4 | Completed | Emory University | 51 | 2024-10-14 | 2026-03-30 |
| Responses to Live Attenuated Influenza Virus (LAIV) in Chronic Obstructive Pulmonary Disease (COPD) LAIV - COPD | Early Phase 1 | Completed | University of North Carolina, Chapel Hill | 24 | 2022-10-03 | 2026-06-23 |
| Response to Live Attenuated Influenza Vaccine in Tonsillar Tissues and Blood FluMist - Influenza | Phase 4 | Withdrawn | Stanford University | 2019-04-15 | 2023-11-21 | |
| Safety of Nasal Influenza Immunisation in Children With Asthma Administration of Live attenuated influenza vaccine (LAIV) - Asthma | Phase 4 | Completed | Imperial College London | 479 | 2016-10-01 | 2019-05-10 |
| Efficacy & Safety of Nasal Influenza Immunisation in Children Live attenuated influenza vaccine, Surveillance (nasal swabbing) during influenza season - Influenza Vaccines Efficacy and Safety | Phase 4 | Completed | Imperial College London | 276 | 2015-10-01 | 2019-12-11 |
| Tissue-specific Responses to Influenza Immunization and Their Relation to Blood Biomarkers (SLVP032) Fluzone®, FluMist® - Influenza | Phase 4 | Terminated | Stanford University | 3 | 2015-09-01 | 2017-05-10 |
| The Effect of Live Attenuated Inactivated Influenza Vaccine on Experimental Human Pneumococcal Carriage Study Study one: LAIV + Inoculation, Study one: Placebo + Inoculation, Study two: Inoculation + LAIV - Pneumonia, Influenza, Human | Phase 4 | Completed | Liverpool University Hospitals NHS Foundation Trust | 324 | 2015-08-01 | 2018-04-18 |
| Adaptive Immune Responses and Repertoire in Influenza Vaccination and Infection (SLVP031) Fluzone®, FluMist® - Influenza | Phase 4 | Terminated | Stanford University | 10 | 2014-11-19 | 2017-09-12 |
| The Role of CD4+ Memory Phenotype, Memory, and Effector T Cells in Vaccination and Infection Fluzone®, FluMist® - Influenza, Healthy | Phase 1 | Completed | Stanford University | 80 | 2014-09-30 | 2020-02-13 |
| Innate and Acquired Immunity to Influenza Infection and Immunization (SLVP029) Fluzone®, FluMist® - Influenza | Phase 4 | Completed | Stanford University | 77 | 2014-09-17 | 2018-12-14 |
| Randomized Study of Immune Response to Licensed Influenza Vaccines in Children and Adolescents LAIV, IIV - Immune Response to Influenza Vaccine, Influenza A Virus Infection | Phase 4 | Completed | Marshfield Clinic Research Foundation | 131 | 2014-09-01 | 2018-04-26 |
| Home Administration of FluMist by Parents/Caregivers FluMist - Influenza | Not applicable | Completed | University of North Carolina, Chapel Hill | 41 | 2014-09-01 | 2016-05-26 |
| Effects of Tobacco Products on Live Attenuated Influenza Virus (LAIV) Infections in Human Volunteers LAIV - Influenza, Human, Smoking | Completed | University of North Carolina, Chapel Hill | 62 | 2014-06-01 | 2018-04-04 | |
| Safety of Nasal Influenza Immunisation in Egg Allergic Children Administration of Live attenuated influenza vaccine - Egg Hypersensitivity | Completed | University Hospital Southampton NHS Foundation Trust | 282 | 2013-09-01 | 2020-08-10 | |
| LAIV (Flumist®) Administration in CF Patients Flumist® - Cystic Fibrosis | Unknown | McGill University Health Centre/Research Institute of the McGill University Health Centre | 170 | 2013-08-01 | 2014-09-16 | |
| An Open Label Study of IgG Fc Glycan Composition in Human Immunity IM Pneumococcal, meningococcal, or flu vaccine - Healthy | Early Phase 1 | Terminated | Rockefeller University | 129 | 2013-03-01 | 2024-09-19 |
Showing 20 of 75. Sign in to see all of them.
Influenza, Human (60) · Neoplasms (2) · Anaphylaxis (1) · Asthma (1) · Central Nervous System Neoplasms (1) · Cystic Fibrosis (1) · Egg Hypersensitivity (1) · HIV Infections (1) · Habits (1) · Hypertrophy (1) · Pneumonia (1) · Premature Birth (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiratory Tract Infections (1) · Rhinitis, Allergic (1)
MedImmune LLC (28) · Stanford University (10) · National Institute of Allergy and Infectious Diseases (NIAID) (6) · University of North Carolina, Chapel Hill (5) · Imperial College London (2) · University of Rochester (2) · AIM ImmunoTech Inc. (1) · Baylor College of Medicine (1) · Copenhagen Respiratory Research (1) · Emory University (1) · Henry M. Jackson Foundation for the Advancement of Military Medicine (1) · International Maternal Pediatric Adolescent AIDS Clinical Trials Group (1) · International Vaccine Institute (1) · Liverpool University Hospitals NHS Foundation Trust (1) · Marshfield Clinic Research Foundation (1)
United States (47) · Finland (4) · United Kingdom (4) · Puerto Rico (2) · South Africa (2) · Australia (1) · Belgium (1) · Canada (1) · Denmark (1) · Hong Kong (1) · Norway (1) · Singapore (1) · South Korea (1)
Robert Walker, MD (15) · Cornelia Dekker, MD (7) · Harry Greenberg, MD (4) · Xiaosong He, PhD (4) · Mark Davis, PhD (3) · Stephen Quake, PhD (3) · Ann Arvin, MD (2) · Cornelia L Dekker, MD (2) · Garry Nolan, PhD (2) · Maria Allende, M.D. (2) · Mark M Davis, PhD (2) · Patricia L Hibberd, MD, PhD (2) · Paul J Turner (2) · Raburn Mallory, MD (2) · Seth Toback, M.D. (2)
PMID 12915495, PMID 14706961, PMID 15694506, PMID 16140685, PMID 17167135, PMID 17395338, PMID 17698577, PMID 18299305, PMID 18310199, PMID 18401289, PMID 19395948, PMID 19776407, PMID 19796721, PMID 20036102, PMID 20581690, PMID 20638452, PMID 21028955, PMID 21285968, PMID 21378375, PMID 21440036, PMID 21496468, PMID 21513761, PMID 21846636, PMID 21949042, PMID 21998477, PMID 22071326, PMID 25039393, PMID 25128802, PMID 25165161, PMID 25425696, PMID 25684279, PMID 25858957, PMID 26117150, PMID 26148331, PMID 27154411, PMID 27247344, PMID 27789145, PMID 27938896, PMID 28368530, PMID 28874545, PMID 28899626, PMID 28963118, PMID 29706550, PMID 31117986, PMID 31250024, PMID 31269273, PMID 31642899, PMID 33095645, PMID 35139037
U19AI057229 (9), 2015 (1), 2016 (1), P50HL120100 (1), R01AI041050 (1), R01ES013611 (1), R01ES036209 (1), R01HL150081 (1), U01AI068632 (1), U19AI090019 (1)