16 completed, 10 recruiting, 6 unknown, 6 withdrawn. 15 Not applicable, 12 Phase 1, 11 Phase 2, 5 Phase 4, 2 Early Phase 1.
Follow Gadolinium: new trials by email Literature Review of Gadolinium trials Research Report on Gadolinium
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 4D-Flow MRI Assessment of Portal Hypertension and TIPS Outcomes in Cirrhosis 4D-Flow Liver and heart MRI with Gadolinium injection, Samples Without DNA - Cirrhosis, Portal Hypertension | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 60 | 2026-08-25 | 2026-10-13 |
| ELUDYN: Assessment of Intra-individual Variability of Vascular Dynamics of Gadopiclenol Injection Parameters in Contrast-enhanced MRI contrast agent, Gadolinium - Contrast Agent, Medical Imaging Data | Phase 4 | Active not recruiting | Hôpital Fribourgeois | 14 | 2026-01-07 | 2026-04-29 |
| Validity of Parametric MRI Using VIRADS Gadolinium - Bladder Cancer | Not applicable | Recruiting | Assiut University | 58 | 2025-12-01 | 2025-10-02 |
| Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy Mangafodipir, Gadolinium - Epilepsy | Phase 1 | Recruiting | National Institute of Neurological Disorders and Stroke (NINDS) | 40 | 2024-11-19 | 2026-10-29 |
| Augmented Reality Feasibility for Non-invasive Preoperative Tracking in Breast Cancer Surgery Additional MRI with gadolinium injection and 3D camera imaging - Subclinical Breast Cancer Lesion | Not applicable | Recruiting | Centre Jean Perrin | 20 | 2024-11-14 | 2025-12-31 |
| Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance MRI of the Brain, Blood draws, Quality of Life Questionnaires - Brain Metastases, Nonsmall Cell Lung Cancer Stage III | Phase 2 | Recruiting | Wake Forest University Health Sciences | 60 | 2023-08-30 | 2026-07-17 |
| Study of Tumor Treating Fields With Hypofractionated Chemoradiotherapy in Newly Diagnosed Glioblastoma Optune, Gadolinium, Temozolomide - Glioblastoma, Newly Diagnosed Glioblastoma | Phase 1 | Completed | Stanford University | 12 | 2021-05-21 | 2025-12-26 |
| CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine Leiomyosarcoma Gemcitabine, Dacarbazine, Cytoreductive Surgery - LMS - Leiomyosarcoma, Uterine Leiomyosarcoma | Phase 2 | Completed | Stanford University | 17 | 2021-01-28 | 2026-06-25 |
| PET/MRI, 18F-FDG PET/CT and Whole Body MRI in Finding Extramedullary Myeloid Leukemia in Patients With Newly Diagnosed Acute Myeloid Leukemia Computed Tomography, Diffusion Weighted Imaging, Fludeoxyglucose F-18 - Acute Myeloid Leukemia, Acute Promyelocytic Leukemia With PML-RARA | Phase 1 | Recruiting | M.D. Anderson Cancer Center | 77 | 2020-07-15 | 2026-10-13 |
| CED of MTX110 Newly Diagnosed Diffuse Midline Gliomas Infusate with MTX110 and gadolinium, Convection-Enhanced Delivery (CED) - Diffuse Intrinsic Pontine Glioma, Diffuse Pontine and Thalamic Gliomas | Phase 1 | Completed | Luca Szalontay | 9 | 2020-03-10 | 2023-12-18 |
| Diffusion MRI for Head and Neck Cancer PET/MRI with FDG, MRI scan without contrast, MRI with gadolinium - Head Cancer Neck | Not applicable | Active not recruiting | NYU Langone Health | 16 | 2019-10-16 | 2026-01-22 |
| Severe Sepsis in Children - IMPRESS-C Iodohippurate, 24 hour ambulatory Blood Pressure, Peripheral Arterial Tonometry - Acute Kidney Injury, Chronic Kidney Disease | Withdrawn | University of Florida | 2019-10-01 | 2020-12-09 | ||
| Feasibility of FMISO in Brain Tumors ¹⁸F-Fluoromisonidazole, Computed Tomography, Magnetic Resonance Imaging - IDH Wild Type Glioblastoma | Phase 2 | Recruiting | OHSU Knight Cancer Institute | 77 | 2019-06-01 | 2026-09-18 |
| Metabolic Characteristics of Brain Tumors Using Hyperpolarized Carbon-13 Magnetic Resonance Spectroscopic Imaging (MRSI) Hyperpolarized 13C-Pyruvate, Gadolinium - Brain Tumor Adult | Recruiting | University of Texas Southwestern Medical Center | 25 | 2019-06-01 | 2026-03-10 | |
| Hyperpolarized Carbon C 13 Pyruvate Magnetic Resonance Spectroscopic Imaging in Detecting Lactate and Bicarbonate in Participants With Central Nervous System Tumors Gadolinium, Hyperpolarized Carbon C 13 Pyruvate, Magnetic Resonance Imaging - Malignant Central Nervous System Neoplasm, Metastatic Malignant Neoplasm in the Central Nervous System | Phase 1 | Completed | Daniel M. Spielman | 9 | 2018-11-06 | 2023-12-21 |
| Chronic Convection Enhanced Delivery of Topotecan Topotecan, Gadolinium, Synchromed II infusion pumps - Gliomas | Phase 1 | Completed | Columbia University | 5 | 2018-01-18 | 2026-04-22 |
| Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System Ferumoxytol, Gadolinium, Magnetic Resonance Imaging - Central Nervous System Neoplasm, Cranial Nerve Disorder | Phase 2 | Recruiting | OHSU Knight Cancer Institute | 150 | 2017-10-06 | 2026-09-14 |
| Use of Gadolinium in CT Pulmonary Angiography Gadolinium - Pulmonary Embolism | Phase 4 | Withdrawn | Massachusetts General Hospital | 2017-07-01 | 2020-02-17 | |
| Ventilation and Pulmonary Endothelium Toxicities of E-cigarettes: A Randomized Crossover Pilot Study E-cigarette, Sham, Hyperpolarized 3-Helium - Pulmonary Disease, Chronic Obstructive, E-cigarettes | Early Phase 1 | Completed | Columbia University | 12 | 2017-03-01 | 2020-10-22 |
| A Feasibility Study to Assess the Use of Gadolinium in Computed Tomography Gadolinium - Contrast Media Allergy | Phase 4 | Withdrawn | Massachusetts General Hospital | 2016-12-01 | 2021-05-04 |
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Brain Neoplasms (4) · Hypertension (3) · Renal Insufficiency, Chronic (3) · Acute Kidney Injury (2) · Central Nervous System Neoplasms (2) · Coronary Artery Disease (2) · Glioblastoma (2) · Glioma (2) · Prostatic Neoplasms (2) · Acromegaly (1) · Breast Neoplasms (1) · Carcinoma, Hepatocellular (1) · Carcinoma, Intraductal, Noninfiltrating (1) · Carcinoma, Non-Small-Cell Lung (1) · Cranial Nerve Diseases (1)
OHSU Knight Cancer Institute (6) · Stanford University (4) · ASIS Corporation (3) · Assistance Publique - Hôpitaux de Paris (2) · Columbia University (2) · Massachusetts General Hospital (2) · NYU Langone Health (2) · University of Florida (2) · li nguyen (2) · American College of Radiology Imaging Network (1) · Assiut University (1) · Centre Jean Perrin (1) · Daniel M. Spielman (1) · Daniel S. Berman (1) · Hôpital Fribourgeois (1)
United States (36) · France (4) · Canada (1) · Egypt (1) · Netherlands (1) · Poland (1) · Switzerland (1)
Edward Neuwelt (4) · Li Nguyen, MD (4) · Marie-Carmelle Elie, MD (2) · Thanh Phung, MD (2) · Thanh Phung,, MD (2) · Adam Liebert, Prof. (1) · Amita Sharma, MD (1) · Andrei H Iagaru (1) · Brian Rutt, PhD (1) · Charles Cunningham, PhD (1) · Christina L Goldstein, MD (1) · Daniel S Berman, MD (1) · David L Gorden, MD (1) · Dawid Schellingerhout (1)
PMID 21964696, PMID 24110368, PMID 25103913, PMID 27635086, PMID 32183076, PMID 33201207, PMID 36243020, PMID 37549351
R01CA137488 (3), 2025 (1), P30CA012197 (1), P30CA014089 (1), P30CA069533 (1), R01CA161404 (1), R01CA245097 (1), R37CA288577 (1), U01CA079778 (1), U01CA080098 (1)