44 completed, 18 unknown, 7 recruiting, 4 terminated. 53 Not applicable, 10 Phase 4, 5 Phase 3, 2 Phase 1, 2 Phase 2.
Follow Trabeculectomy: new trials by email Literature Review of Trabeculectomy trials Research Report on Trabeculectomy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Trabeculectomy Versus MicroShunt Implantation in Glaucoma Surgery (TIGER) Preserflo MicroShunt, Trabeculectomy - Glaucoma | Not applicable | Not yet recruiting | Oslo University Hospital | 100 | 2026-10-01 | 2026-10-09 |
| Combined Phacoemulsification-Goniotomy in Primary Open-Angle and Primary Angle-Closure Glaucoma Combined Phacoemulsification and Goniotomy - Primary Open-Angle Glaucoma, Primary Angle-Closure Glaucoma | Not applicable | Not yet recruiting | Assiut University | 70 | 2026-10-01 | 2026-09-16 |
| Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries Goniotomy - Open Angle Glaucoma (OAG), Primary Open Angle Glaucoma (POAG) | Not applicable | Not yet recruiting | Henry Ford Health System | 132 | 2026-07-01 | 2026-06-11 |
| Preserflo MicroShunt Versus Trabeculectomy Preserflo MicroShunt Implantation, Trabeculectomy with MMC - GLAUCOMA 1, OPEN ANGLE, D (Disorder) | Not applicable | Recruiting | Medical University of Bialystok | 100 | 2026-03-01 | 2026-03-27 |
| iStent Inject Versus Goniotomy With Kahook Dual Blade in Glauocma Treatment Goniotomy with KDB blade goniotomy, Two iStent inject implanation - Open Angle Glaucoma (OAG) | Not applicable | Recruiting | Medical University of Bialystok | 100 | 2026-01-01 | 2026-01-08 |
| SCTSC Versus Trabeculectomy in Medically Uncontrolled Open-Angle Glaucoma in Pseudophakic Patients Trabeculectomy, Slow coagulation trans-scleral cyclophotocoagulation - Glaucoma, Open Angle | Not applicable | Recruiting | Minia University | 50 | 2025-07-20 | 2025-09-25 |
| Comparison of Phaco Surgery With Goniosynechialysis Versus Trabeculectomy in Glaucoma Treatment Phacoemulsification with Goniosynechialysis, Trabeculectomy with 5FU - Primary Angle Closure Glaucoma | Not applicable | Recruiting | University of Medicine and Pharmacy at Ho Chi Minh City | 82 | 2025-06-01 | 2025-09-11 |
| Kahook Dual Blade Goniotomy in Chronic Primary Angle-Closure Glaucoma Kahook Dual Blade (KDB) goniotomy, phacoemulsification with intraocular lens implantation combined with goniosynechialysis - Primary Angle-closure Glaucoma | Not applicable | Recruiting | Peking University People's Hospital | 68 | 2025-03-01 | 2026-04-08 |
| Deep Sclerectomy With Scleral Bed Fenestration Versus Trabeculectomy in Medically Uncontrolled Primary Open Angle Glaucoma Patients deep sclerectomy with scleral bed fenestration, Trabeculectomy - Open Angle Glaucoma (OAG) Surgeries, Deep Sclerectomy | Not applicable | Completed | Minia University | 39 | 2025-02-20 | 2026-09-02 |
| Subthreshold Diode Laser Versus Trabeculotomy in Treatment of Advanced Primary Open Angle Glaucoma Subthreshold diode laser, Trabeculotomy - Subthreshold Diode Laser, Trabeculotomy | Not applicable | Completed | Kafrelsheikh University | 80 | 2024-06-01 | 2026-05-18 |
| A Study to Evaluate Adverse Events and Change in Disease Activity With the XEN45 Glaucoma Treatment System Implantation In Adult Participants With Open-Angle Glaucoma in China XEN45 Glaucoma Treatment System, Trabeculectomy - Open-angle Glaucoma, OAG | Phase 4 | Active not recruiting | AbbVie | 120 | 2024-01-09 | 2026-04-28 |
| Platelet-rich Fibrin(PRF) Membrane in Ophthalmic Diseases PRF membrane tamponade surgery in macular hole, ILM peeling in macular hole, PRF membrane grafting in pterygium - Platelet-rich Fibrin, Macular Holes | Not applicable | Unknown | Lei Du | 170 | 2023-01-01 | 2024-01-12 |
| UBM Guided Site and Extent of Trabeculotomy in Pediatric Glaucoma trabeculotomy ( angle glaucoma surgery ) - Glaucoma Pediatric | Not applicable | Unknown | Mansoura University | 40 | 2022-09-01 | 2022-09-07 |
| Deep Sclerectomy Versus Trabeculectomy in Normal Tension Glaucoma Trabeculectomy, Deep Sclerectomy - Normal Tension Glaucoma | Not applicable | Recruiting | Helsinki University Central Hospital | 80 | 2022-05-31 | 2024-03-15 |
| NorMIGS - a Study of Micro-invasive Glaucoma Surgery Preserflo microshunt, Trabeculectomy, Other MIGS - Glaucoma | Recruiting | Oslo University Hospital | 100 | 2022-04-22 | 2022-11-29 | |
| Study of OMNI Surgical System and iStent for Eyes With OAG (Trident) Canaloplasty and trabeculotomy with the OMNI system., iStent inject, Canaloplasty - Glaucoma, Open-Angle | Not applicable | Terminated | Sight Sciences, Inc. | 10 | 2022-01-11 | 2025-10-27 |
| Trabeculectomy Versus Peripheral Iridectomy Plus Goniotomy in Advanced PACG Trabeculectomy, SPI+GSL+GT - Primary Angle Closure Glaucoma | Not applicable | Unknown | Sun Yat-sen University | 88 | 2022-01-05 | 2022-06-14 |
| Evaluation of Minimal Invasive Glaucoma Surgery Trabeculectomy, XEN®, Preserflo® - Glaucoma | Not applicable | Unknown | Medical University of Graz | 150 | 2021-12-21 | 2023-03-23 |
| eyeWatch vs. Trabeculectomy RCT (evT) eyeWatch - Primary Glaucoma | Not applicable | Unknown | Dr. Kaweh Mansouri | 80 | 2021-06-30 | 2022-05-10 |
| Phacotrabeculectomy Versus Phacogoniotomy (PVP) in Advanced Primary Angle-closure Glaucoma phacoemulsification with intraocular lens implantation combined with goniosynechialysis and goniotomy, phacoemulsification with intraocular lens implantation combined with trabeculectomy - Glaucoma, Angle-Closure | Not applicable | Active not recruiting | Sun Yat-sen University | 124 | 2021-05-31 | 2024-12-11 |
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Glaucoma (45) · Glaucoma, Open-Angle (28) · Glaucoma, Angle-Closure (9) · Cataract (7) · Hydrophthalmos (4) · Glaucoma, Neovascular (3) · Astigmatism (1) · Corneal Endothelial Cell Loss (1) · Corneal Ulcer (1) · Exfoliation Syndrome (1) · Eye Diseases (1) · Low Tension Glaucoma (1) · Pterygium (1) · Retinal Perforations (1) · Retinal Vein Occlusion (1)
Assiut University (3) · Sun Yat-sen University (3) · Aeon Astron Europe B.V. (2) · L.V. Prasad Eye Institute (2) · Mansoura University (2) · Medical University of Bialystok (2) · Minia University (2) · National Eye Institute (NEI) (2) · Oslo University Hospital (2) · Pro Top & Mediking Company Limited (2) · Sight Sciences, Inc. (2) · Siriraj Hospital (2) · Technische Universität Dresden (2) · University of Cologne (2) · University of Miami (2)
United States (13) · Egypt (9) · Germany (9) · Canada (7) · China (6) · United Kingdom (5) · France (3) · India (3) · Iran (3) · Spain (3) · Austria (2) · Italy (2) · Norway (2) · Poland (2) · Singapore (2)
Jaime Dickerson, PhD (2) · Ahmed M Eid, MD (1) · Alexander Spratt, MBBCh FRCOphth (1) · Angelo Tanna, MD (1) · Balwantray C Chauhan, Ph.D. (1) · Catherine Birt, MD (1) · Catherine Creuzot-Gracher, MD, PhD (1) · Ching Lin Ho (1) · Clemens Vass, Univ.Prof.Dr.med.univ. (1) · Crystal McAfee, MA-HHSA (1) · Dale K Heuer, M.D. (1) · Dale K Heuer, MD (1)
PMID 36912740, PMID 31727428, PMID 10937547, PMID 17122118, PMID 17471324, PMID 18173426, PMID 18425438, PMID 18695095, PMID 19152871, PMID 19277230, PMID 19674729, PMID 20126489, PMID 20696979, PMID 21336149, PMID 21467178, PMID 22244522, PMID 22245458, PMID 22805056, PMID 22986111, PMID 23429629, PMID 24210765, PMID 24531027, PMID 24727262, PMID 24906863, PMID 25272084, PMID 25336577, PMID 25580888, PMID 25812531, PMID 25908002, PMID 26315044, PMID 26674779, PMID 26766400, PMID 27082559, PMID 27574396, PMID 28034308, PMID 28408039, PMID 29477688, PMID 29613978, PMID 31294768, PMID 31976190, PMID 32622848, PMID 33031110, PMID 33657420, PMID 33671386, PMID 34880029, PMID 35179414, PMID 35788072, PMID 35943114, PMID 36721130, PMID 36972738
2014 (1), 2018 (1)