90 completed, 70 unknown, 43 recruiting, 21 terminated. 64 Not applicable, 34 Phase 2, 24 Phase 3, 10 Phase 1, 10 Phase 4.
Follow this condition Literature Review of Cardiotoxicity trials Research Report on Cardiotoxicity
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| PAtient Similarity for Decision-Making in Prevention of Cardiovascular Toxicity (PACT): A Feasibility Study Clinical Decision Aid, Standard Care - Heart Failure, Coronary Artery Disease | Not yet recruiting | Medical College of Wisconsin | 60 | 2026-12-01 | 2025-10-14 | |
| Positron Emission Tomography (PET) Imaging of Chemotherapy-Induced Cardiotoxicity 68Ga-Galmydar, PET/MRI, 18F-FDG - Lymphoma Cancer, Breast Cancer | Phase 1 | Not yet recruiting | Washington University School of Medicine | 36 | 2026-11-01 | 2026-09-24 |
| Monitoring for CardioToxicity Using WeArable deVices While Undergoing cancEr Treatments (MCT-WAVE) Mobile Cardiac Telemetry, Wearable Cardiac Monitor - Cardiotoxicity, Cancer | Not applicable | Not yet recruiting | University of Minnesota | 72 | 2026-10-29 | 2026-10-06 |
| Cardiac Biomarkers in Patients Receiving Immune Checkpoint Inhibitors (PRIME-ICI) Cardiotoxicity, Cardiac Biomarkers | Not yet recruiting | South Tees Hospitals NHS Foundation Trust | 300 | 2026-10-12 | 2026-10-08 | |
| Cardioprotection Effect of Linagliptin Doxorubicin, Empaglifloz 5 mg orally once daily - Cardiotoxicity | Phase 3 | Not yet recruiting | Tanta University | 140 | 2026-10-01 | 2026-10-15 |
| Heart Failure in Women: Epidemiological and Prognostic Insights Heart Failure | Recruiting | Carolina Ortiz Cortes | 430 | 2026-09-17 | 2026-10-21 | |
| Prospective Study on Radiation Induced Cardiotoxicity Assessed By PET-CT for Locally Advanced Non-Small Cell Lung Cancer (NSCLC) PET/CT 18F-Flurpiridaz Rest/Stress Test, Coronary CT Angiography (CCTA), 18F-Flurpiridaz - Non Small Cell Lung Cancer, Cardiotoxicity | Phase 2 | Recruiting | Indiana University | 10 | 2026-09-01 | 2026-09-15 |
| The CARDIOPROTECT Trial Dexrazoxane, Dexrazoxane placebo, Doxorubicin - Diffuse Large B-cell Lymphoma (DLBCL), Cardiotoxicity | Phase 2 | Recruiting | Beth Israel Deaconess Medical Center | 60 | 2026-08-31 | 2026-07-27 |
| Sotagliflozin as Prevention of Anthracycline-Related Cardiotoxicity Sotagliflozin, Placebo - Anthracycline-induced Cardiotoxicity, Lymphoma | Phase 2 | Not yet recruiting | Icahn School of Medicine at Mount Sinai | 60 | 2026-07-01 | 2026-05-07 |
| Development of a Pharmacogenomic Panel for Early Detection of Chemotherapy- and Immunotherapy-Induced Cardiotoxicity. Cardiotoxicity | Recruiting | Beneficência Portuguesa de São Paulo | 1000 | 2026-05-11 | 2026-06-23 | |
| Cardiac Side Effects of Systemic Therapy in Early-Stage Breast Cancer Breast Cancer (Early Breast Cancer), Cardiotoxicity | Recruiting | Fatih GURLER | 100 | 2026-05-11 | 2026-09-16 | |
| JUdicious Surveillance for Trastuzumab Induced Cardiotoxicity in the First Year Intervention - Low Risk Group OR Intermediate Risk Group - Cardiovascular Health, Breast Cancer | Not applicable | Recruiting | Women's College Hospital | 300 | 2026-04-22 | 2026-06-15 |
| Artificial Intelligence for Reconstruction of Echocardiography Studies V-echo, L-echo - Cardiotoxicity | Not yet recruiting | The Royal Wolverhampton Hospitals NHS Trust | 120 | 2026-04-01 | 2026-02-11 | |
| Serial Cardiac Magnetic Resonance Imaging (CMR) With Contrast Agents and Biomarker Analysis for the Detection of Cardiotoxicity Under Anthracycline-containing Cancer Therapy CMR based measurement of cardiotoxicity, biosampling for scientific research in study-specific biobank - Cardiotoxicity, Anthracycline-induced Cardiotoxicity | Not applicable | Recruiting | Robert Bosch Gesellschaft für Medizinische Forschung mbH (RBMF) | 93 | 2026-03-04 | 2026-04-14 |
| Impact of Exercise Intensity on Cardiac Health in Young Adult Survivors of Childhood Cancer: The PULSE Trial HIIT Exercise Program, MICT Exercise Program - Childhood Cancer Survivors, Cardiotoxicity | Not applicable | Active not recruiting | Dana-Farber Cancer Institute | 20 | 2026-03-04 | 2026-03-18 |
| Rosuvastatin for Prevention of Anthracycline-induced Cardiac Dysfunction in Breast Cancer Patients Rosuvastatin 20 mg/day, Placebo tablets similar to rosuvastatin 20mg tablets - Anthracycline-induced Cardiac Toxicity, Breast Cancer | Phase 4 | Not yet recruiting | Shiraz University of Medical Sciences | 400 | 2026-02-01 | 2025-12-10 |
| In-Bedroom Renewed Air as Anti-inflammatory Adjuvant Therapy in Cancer Survivors High efficiency particulate air filtration system (nightly administration), High efficiency particulate air filtration system (nightly and daily administration), Air filtration system without filters (sham) - Cancer Survivors, Cardiotoxicity | Not applicable | Completed | University College, London | 10 | 2026-01-23 | 2026-08-04 |
| Cardiovascular Complications in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation. Cardiotoxicity, DPP3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 400 | 2025-12-25 | 2026-09-25 | |
| ML Score Prediction of Cardiotoxicity in Cancer Patients Receiving Anthracycline Chemotherapy or HER2-Targeted Therapies Cardiotoxicity, Heart Failure | Recruiting | University Hospital, Caen | 600 | 2025-10-29 | 2026-03-19 | |
| Novel On-body Evaluation of Cardiac Health for Oncology Cardiotoxicity, Heart Failure | Enrolling by invitation | Skribe Medical | 1000 | 2025-10-09 | 2026-10-05 |
Showing 20 of 255. Sign in to see all of them.
Breast Neoplasms (99) · Heart Failure (44) · Neoplasms (43) · Lymphoma (20) · Cardiovascular Diseases (15) · Cardiomyopathies (10) · Motor Activity (9) · Heart Diseases (8) · Lung Neoplasms (8) · Ventricular Dysfunction, Left (8) · Carcinoma, Non-Small-Cell Lung (7) · Hodgkin Disease (6) · Leukemia (6) · Lymphoma, Non-Hodgkin (6)
Pathologic Processes (255) · Pathological Conditions, Signs and Symptoms (255) · Wounds and Injuries (255) · Chemically-Induced Disorders (254) · Drug-Related Side Effects and Adverse Reactions (251) · Radiation Injuries (249) · Heart Diseases (247) · Cardiovascular Diseases (240) · Neoplasms (135) · Neoplasms by Site (121) · Skin Diseases (101) · Skin and Connective Tissue Diseases (101) · Breast Diseases (98) · Neoplasms by Histologic Type (43) · Hemic and Lymphatic Diseases (40)
Doxorubicin (19) · Echocardiography (18) · Cyclophosphamide (10) · Dexrazoxane (10) · Exercise (9) · Electrocardiography (8) · Trastuzumab (8) · Carvedilol (7) · Razoxane (6) · Vincristine (5) · Atorvastatin (4) · Docetaxel (4) · Filgrastim (4) · Radiotherapy (4) · Anthracyclines (3)
Abramson Cancer Center at Penn Medicine (10) · Children's Oncology Group (5) · Groupe Hospitalier Pitie-Salpetriere (5) · University College, London (5) · Ain Shams University (4) · Assistance Publique - Hôpitaux de Paris (4) · Peking University Third Hospital (4) · Washington University School of Medicine (4) · AHS Cancer Control Alberta (3) · Istanbul University (3) · Memorial Sloan Kettering Cancer Center (3) · National Cancer Institute (NCI) (3) · Radboud University Medical Center (3) · Tanta University (3) · University Health Network, Toronto (3)
United States (68) · Canada (24) · France (21) · China (16) · United Kingdom (15) · Italy (13) · Netherlands (12) · Egypt (11) · Spain (9) · Brazil (7) · Germany (6) · Poland (6) · Switzerland (6) · Turkey (Türkiye) (6) · Australia (5)
Bonnie Ky, MD, MSCE (6) · Cafer Zorkun, MD PhD (3) · Marielle Scherrer-Crosbie, MD, PhD (3) · Anthony Yu, MD (2) · Cindy Schwartz, MD (2) · Laurence J. van Warmerdam, MD, PhD (2) · Zhi Yang, PhD (2) · A. van Rhenen, MD (1) · Ahmed L Mohamed, Master (1) · Alison Macklin (1) · Alister Hart, MD,FRCSG (1) · Allan Kluser Sales, PhD (1) · Andrea Natale, MD (1)
PMID 36207229, PMID 10761937, PMID 11263649, PMID 11913479, PMID 12948221, PMID 13211322, PMID 14349898, PMID 15473335, PMID 15477280, PMID 16131888, PMID 16332601, PMID 16568436, PMID 17068719, PMID 18757952, PMID 18827237, PMID 18835128, PMID 19257889, PMID 19304018, PMID 19483225, PMID 19584400, PMID 19794161, PMID 19937124, PMID 20544916, PMID 20859129, PMID 21037026, PMID 21656317, PMID 21692725, PMID 21794114, PMID 21969427, PMID 22252702, PMID 22308623, PMID 22336970, PMID 22351785, PMID 22374741, PMID 22419548, PMID 22447496, PMID 22455358, PMID 22520206, PMID 22689804, PMID 22723536, PMID 22911615, PMID 23090916, PMID 23273589, PMID 23307670, PMID 23313008, PMID 23421810, PMID 23762480, PMID 23813157, PMID 23948123, PMID 24103764
2009 (1), 2019 (1), 2023 (1), P30CA012197 (1), P30CA015083 (1), P30CA036727 (1), P30CA068485 (1), R01CA167821 (1), R01HL180913 (1), R21CA226960 (1), R21HL150723 (1), R21HL152148 (1), U01CA097452 (1), U10CA030969 (1), U10CA031946 (1)