16 completed. 16 Phase 2, 5 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 16 | Completed 16 |
| Phase 1 | 5 | Completed 5 |
| Phase 3 | 2 | Completed 2 |
Follow Kidney Failure: new trials by email Literature Review of Kidney Failure trials Research Report on Kidney Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| SGLT2 Inhibition in Hemodialysis Dapagliflozin 10 MG, Placebo - Kidney Failure, Hemodialysis | Phase 2 | Completed | Medical University of Vienna | 220 | 2022-10-01 | 2026-03-03 |
| C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI C1 Esterase Inhibitor, Placebo - End Stage Renal Disease, Kidney Failure | Phase 1 / Phase 2 | Completed | Cedars-Sinai Medical Center | 70 | 2014-09-01 | 2018-06-25 |
| Quantitative Mass Transfer of SFP-iron From Dialysate to Blood in CKD-HD Patients Soluble Ferric Pyrophosphate, Placebo - Kidney Failure | Phase 1 / Phase 2 | Completed | Rockwell Medical Technologies, Inc. | 12 | 2013-07-01 | 2015-02-16 |
| Eculizumab for Prevention and Treatment of Kidney Graft Reperfusion Injury eculizumab - End-Stage Renal Disease, Kidney Failure | Phase 2 | Completed | Russian Academy of Medical Sciences | 57 | 2012-09-01 | 2018-08-31 |
| Mesenchymal Stem Cells After Renal or Liver Transplantation Mesenchymal Stem Cells - Liver Failure, Kidney Failure | Phase 1 / Phase 2 | Completed | University of Liege | 40 | 2012-02-01 | 2022-06-14 |
| Safety and Efficacy Study of the Venous Window Needle Guide to Access Arteriovenous (AV)Fistulae Venous Window Needle Guide - End Stage Renal Disease, AV Fistula | Phase 2 / Phase 3 | Completed | Vital Access Corp. | 54 | 2011-12-01 | 2016-06-03 |
| Erythropoietin (EPO) to Protect Renal Function After Cardiac Surgery Erythropoietin zeta, Placebo - Kidney Failure, Renal Failure | Phase 2 | Completed | Region Skane | 75 | 2011-10-01 | 2013-10-25 |
| Treatment of Early Stage Renal Failure With Active Vitamin D or a Phosphate Binder. Renvela, Etalpha - Kidney Failure | Phase 2 | Completed | Helse Stavanger HF | 21 | 2010-10-01 | 2012-11-09 |
| Donor Simvastatin Treatment in Organ Transplantation Simvastatin 80mg, Control Rx - Heart Failure, Respiratory Failure | Phase 2 / Phase 3 | Completed | Helsinki University Central Hospital | 84 | 2010-06-01 | 2017-09-19 |
| Safety Trial of Single Versus Multiple Dose Thymoglobulin Induction in Kidney Transplantation Single-dose rabbit Anti-thymocyte Globulin induction, Divided-dose rabbit Anti-thymocyte Globulin induction - End-Stage Renal Disease, Kidney Failure | Phase 2 | Completed | Wright State University | 99 | 2010-03-01 | 2015-12-07 |
| Pharmacokinetics of LCP-Tacro(TM) Once Daily And Prograf® Twice A Day in Adult De Novo Kidney Transplant Patients Tacrolimus (Tacro™), Prograf - Kidney Failure, Renal Failure | Phase 2 | Completed | Veloxis Pharmaceuticals | 63 | 2008-09-01 | 2015-05-19 |
| Angiotensin Converting Enzyme Inhibitors & Contrast Induced Nephropathy in Patients Receiving a Cardiac Catheterization Hold ACEI or ARB - Kidney Failure | Phase 2 | Completed | Hamilton Health Sciences Corporation | 220 | 2006-07-01 | 2012-10-22 |
| Using Donor Stem Cells and Alemtuzumab to Prevent Organ Rejection in Kidney Transplant Patients Alemtuzumab, Mycophenolate mofetil, Sirolimus - Kidney Transplantation, Kidney Disease | Phase 1 / Phase 2 | Completed | University of Miami | 9 | 2004-09-01 | 2012-10-02 |
| Acetylcysteine in the Prevention of Renal Failure After Bypass Surgery N-Acetylcysteine - Kidney Failure | Phase 1 / Phase 2 | Completed | Minneapolis Veterans Affairs Medical Center | 102 | 2003-04-01 | 2007-09-19 |
| Sirolimus and Thymoglobulin to Prevent Kidney Transplant Rejection Sirolimus, Thymoglobulin - Kidney Failure | Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 12 | 2000-08-01 | 2019-09-17 |
| Pirfenidone to Treat Kidney Disease (Focal Segmental Glomerulosclerosis) Pirfenidone - Fibrosis, Focal Glomerulosclerosis | Phase 2 | Completed | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 21 | 1999-12-01 | 2014-05-26 |
Renal Insufficiency (16) · Kidney Failure, Chronic (4) · Kidney Diseases (3) · Fibrosis (2) · Liver Failure (2) · Rejection, Psychology (2) · Renal Insufficiency, Chronic (2) · Arteriovenous Fistula (1) · Bronchiolitis Obliterans Syndrome (1) · Camurati-Engelmann Syndrome (1) · Delayed Graft Function (1) · Diabetes Mellitus, Type 2 (1) · Glomerulosclerosis, Focal Segmental (1) · Heart Failure (1) · Hypertrophy, Left Ventricular (1)
Female Urogenital Diseases (16) · Female Urogenital Diseases and Pregnancy Complications (16) · Male Urogenital Diseases (16) · Urogenital Diseases (16) · Urologic Diseases (16) · Kidney Diseases (13) · Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Chronic Disease (5) · Disease Attributes (5) · Cardiovascular Diseases (3) · Renal Insufficiency, Chronic (3) · Behavior (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Digestive System Diseases (2)
Sirolimus (2) · Tacrolimus (2) · thymoglobulin (2) · Acetylcysteine (1) · Alemtuzumab (1) · Complement C1 Inhibitor Protein (1) · Kidney Transplantation (1) · Mycophenolic Acid (1) · Saline Solution (1) · Sevelamer (1) · Simvastatin (1) · Sodium Chloride (1) · Tin Fluorides (1) · alfacalcidol (1) · dapagliflozin (1)
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Cedars-Sinai Medical Center (1) · Hamilton Health Sciences Corporation (1) · Helse Stavanger HF (1) · Helsinki University Central Hospital (1) · Medical University of Vienna (1) · Minneapolis Veterans Affairs Medical Center (1) · Region Skane (1) · Rockwell Medical Technologies, Inc. (1) · Russian Academy of Medical Sciences (1) · University of Liege (1) · University of Miami (1) · Veloxis Pharmaceuticals (1) · Vital Access Corp. (1) · Wright State University (1)
United States (9) · Austria (1) · Belgium (1) · Canada (1) · Finland (1) · Norway (1) · Russia (1) · Sweden (1)
Ashley Vo, PharmD (1) · George W. Burke, III, MD (1) · Henrik Bjursten, M.D. Ph.D (1) · Karl B Lemstrom, MD, PhD (1) · Manfred Hecking, MD, PhD (1) · Mark Crawford, BA (1) · Michael M Kaabak, MD (1) · R.Brian Stevens, MD, PhD (1) · Raymond D Pratt, MC FACP (1) · Rita Alloway, PharmD (1) · Selcuk Adabag, MD (1) · Shamir R Mehta, MD MSc (1) · Stanley C Jordan, MD (1) · Thomas A Zelniker, MD, MSc (1)
PMID 18513531, PMID 22742720, PMID 23903014, PMID 24833247, PMID 26093871, PMID 26696251, PMID 28284916, PMID 31352795, PMID 40576086