32 completed, 21 unknown, 11 terminated, 6 recruiting. 18 Phase 2, 15 Not applicable, 15 Phase 4, 14 Phase 3, 10 Phase 1.
Follow Delayed Graft Function: new trials by email Literature Review of Delayed Graft Function trials Research Report on Delayed Graft Function
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Drone Transport of Deceased-Donor Kidney Grafts Between Two French Hospitals Before Transplantation: a Pilot Safety Study Kidney graft transport by autonomous unmanned aircraft (drone) between the procurement and transplantation centres - Kidney Failure, Chronic, Kidney Transplantation | Not applicable | Not yet recruiting | Nantes University Hospital | 5 | 2027-01-15 | 2026-10-01 |
| TxAccess and Dd-cfDNA for Improved Care of Patients With Delayed Graft Function TxAccess, Donor-Derived Cell-Free DNA (dd-cfDNA) - Delayed Graft Function | Not applicable | Not yet recruiting | Duke University | 450 | 2026-09-15 | 2026-09-17 |
| The Impact of Intraoperative Diuretic Use on Delayed Graft Function Following Deceased Donor Renal Transplantation Furosemide, Mannitol - Delayed Graft Function, Kidney Transplantation | Not applicable | Recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 160 | 2026-09-01 | 2026-09-18 |
| Microvasculature Ultrasound Super-resolution in Transplant Delayed Graft Function Ultrasound contrast agent (Contrast-enhanced ultrasound), Optison (Perflutren Protein-Type A Microspheres Injectable Suspension), Lumason® contrast agent - End Stage Chronic Renal Failure, Renal Transplant | Not yet recruiting | Roderick Tan | 40 | 2026-06-01 | 2026-06-12 | |
| Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults at High Risk of Delayed Graft Function (DGF) Following Kidney Allograft Transplantation Pegcetacoplan, Placebo - Delayed Graft Function, End Stage Renal Disease | Phase 3 | Withdrawn | Apellis Pharmaceuticals, Inc. | 2026-05-18 | 2026-09-02 | |
| The Effects of Vonoprazan Fumarate on DGF Incidence in DD Kidney Transplant Recipients Vonoprazan fumarate - Delayed Graft Function, Kidney Transplantation | Phase 1 / Phase 2 | Recruiting | First Affiliated Hospital of Chongqing Medical University | 47 | 2025-12-10 | 2025-12-23 |
| Amino Acid Infusion in Kidney Transplant Recipients Infusion Therapy, Saline solution infusion - Short-term Graft Function, Metabolic Effects | Not applicable | Not yet recruiting | University Hospital, Martin | 100 | 2025-09-15 | 2025-04-16 |
| Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Efficacy and Safety of Ravulizumab Administered Intravenously in Adult Participants at High Risk of Delayed Graft Function After Kidney Transplantation Ravulizumab, Placebo - Delayed Graft Function, DGF | Phase 3 | Recruiting | Alexion Pharmaceuticals, Inc. | 450 | 2025-05-19 | 2026-06-18 |
| Effect of Terlipressin for Intraoperative Blood Pressure Management in Kidney Transplantation terlipressin, Placebo (Normal Saline) - Kidney Transplant, Delayed Graft Function | Not applicable | Active not recruiting | Beijing Friendship Hospital | 150 | 2025-03-06 | 2026-07-13 |
| Collapsibility Index of the Inferior Vena Cava and Kidney Transplantation No Intervention - Fluid Responsiveness in Early Post-kidney Transplantation Period | Not yet recruiting | CHU de Reims | 150 | 2025-02-01 | 2025-01-29 | |
| Deceased Donor Kidney Storage at 10 Celsius Versus Conventional Storage 10˚C deceased donor kidney storage using Traferox XPort - End Stage Chronic Renal Failure, Chronic Kidney Disease (Stages 4 and 5) | Not applicable | Recruiting | Vanderbilt University Medical Center | 30 | 2024-11-18 | 2026-04-06 |
| Norepinephrine Infusion Combined With Goal-directed Fluid Therapy in Patients Undergoing Kidney Transplantations Goal-Directed Fluid Therapy (GDFT), Regular Fluid Therapy - Delayed Graft Function, End Stage Renal Disease | Not applicable | Unknown | RenJi Hospital | 380 | 2024-03-01 | 2024-04-16 |
| ARGX-117 in Deceased Donor Kidney Transplant Recipients at Risk for Delayed Graft Function ARGX-117, Placebo - Delayed Graft Function | Phase 2 | Active not recruiting | argenx | 103 | 2024-02-17 | 2026-10-14 |
| Ex Vivo Normothermic Perfusion in Kidney Transplantation. Ex vivo normothermic perfusion, Cold preservation - Kidney Transplantation | Not applicable | Recruiting | Ebers Medical Technology, S.L. | 100 | 2023-12-14 | 2026-09-10 |
| Study of the Correlation Between Donor CIRBP and Transplanted Kidney Function Prediction of delayed graft function - Kidney Transplant; Complications, Delayed Graft Function | Completed | Third Affiliated Hospital, Sun Yat-Sen University | 207 | 2023-12-01 | 2024-10-15 | |
| Novel Cooling Device for the Elimination of Warm Ischemia During Renal Transplantation Kidney cooling device - Kidney Transplant; Complications, Delayed Graft Function | Not applicable | Unknown | Thomas Skinner | 45 | 2023-10-01 | 2023-04-21 |
| A Study of the Correlation Between Donor UDP-Glc and Transplanted Kidney Function Renal Transplant | Completed | Qianghua Leng | 200 | 2023-06-01 | 2024-12-03 | |
| Graft Acute Kidney Injury: Vitamin B3 to Facilitate Renal Recovery In the Early Life of a Transplant Nicotinamide treatment, Placebo treatment - Delayed Graft Function | Phase 3 | Completed | Assistance Publique - Hôpitaux de Paris | 204 | 2023-01-12 | 2024-07-10 |
| Intermittent Versus Continuous Surface O2 During HMP of DCD Kidneys Oxygen - Delayed Graft Function, Kidney Transplant; Complications | Phase 3 | Unknown | Cliniques universitaires Saint-Luc- Université Catholique de Louvain | 60 | 2022-03-20 | 2024-05-23 |
| Risk Factors of Chinese Kidney Transplant Recipients DSA Based on MPA Immunosuppressive Regimen Mycophenolate Mofetil Capsules - Kidney Transplant Recipients | Phase 4 | Unknown | First Affiliated Hospital Xi'an Jiaotong University | 300 | 2021-01-22 | 2022-05-27 |
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Kidney Failure, Chronic (8) · Reperfusion Injury (8) · Acute Kidney Injury (6) · Renal Insufficiency, Chronic (4) · Brain Death (3) · Renal Insufficiency (3) · Kidney Diseases (2) · Liver Diseases (2) · Rejection, Psychology (2) · Deafness, Autosomal Recessive 39 (1) · Diabetes Mellitus (1) · Edema (1) · Graft vs Host Disease (1) · Kidney Cortex Necrosis (1)
Pathologic Processes (82) · Pathological Conditions, Signs and Symptoms (82) · Female Urogenital Diseases (22) · Female Urogenital Diseases and Pregnancy Complications (22) · Male Urogenital Diseases (22) · Urogenital Diseases (22) · Urologic Diseases (22) · Kidney Diseases (19) · Renal Insufficiency (16) · Chronic Disease (11) · Disease Attributes (11) · Cardiovascular Diseases (8) · Postoperative Complications (8) · Vascular Diseases (8) · Renal Insufficiency, Chronic (7)
Mycophenolic Acid (7) · Saline Solution (7) · Sodium Chloride (6) · Tacrolimus (5) · Abatacept (4) · Antilymphocyte Serum (3) · Everolimus (3) · Furosemide (3) · eculizumab (3) · Acetylcysteine (2) · Cryopreservation (2) · Cyclosporine (2) · Kidney Transplantation (2) · Sirolimus (2) · thymoglobulin (2)
Angion Biomedica Corp (3) · First Affiliated Hospital Xi'an Jiaotong University (3) · University of Wisconsin, Madison (3) · Y's Therapeutics, Inc. (3) · Alexion Pharmaceuticals, Inc. (2) · Nantes University Hospital (2) · Quark Pharmaceuticals (2) · Apellis Pharmaceuticals, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Beijing Friendship Hospital (1) · CHU de Reims (1) · Cedars-Sinai Medical Center (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1) · Columbia University (1) · Corline Biomedical AB (1)
United States (37) · France (11) · China (10) · Spain (10) · Canada (8) · Germany (7) · Netherlands (7) · Brazil (6) · Australia (5) · United Kingdom (5) · Austria (4) · Belgium (4) · Czechia (4) · Denmark (3) · Italy (3)
Stefan Hemmerich, PhD (3) · Abdolreza Haririan, MD, MPH (1) · Alex Gutierrez-Dalmau, MD (1) · Amir Abdipour, MD (1) · Amir Sedigh, MD (1) · Angelo DeMattos, MD (1) · Arjang Djamali, M.D. (1) · Ashley Vo, PharmD (1) · Baburao Koneru, M.D. (1) · Baburao Koneru, MD (1) · Bente Jespersen, Professor, DMSc, MD (1) · Bernd Schroppel, MD (1) · Bettina Jungwirth, MD (1) · Carole R Ichai, MD, PhD (1)
PMID 20573162, PMID 24056620, PMID 38979743, PMID 10580071, PMID 12194926, PMID 12694055, PMID 14961990, PMID 15257455, PMID 15541456, PMID 17908276, PMID 18294347, PMID 18336697, PMID 18946341, PMID 19103734, PMID 19118301, PMID 19829730, PMID 19843031, PMID 19875806, PMID 20331689, PMID 20814351, PMID 20833822, PMID 20883559, PMID 21037431, PMID 21114535, PMID 21161683, PMID 21332580, PMID 21454065, PMID 21454067, PMID 21585547, PMID 21834917, PMID 21993970, PMID 22356343, PMID 22429309, PMID 22745272, PMID 22755430, PMID 22755431, PMID 22823748, PMID 22893495, PMID 22959074, PMID 22974955, PMID 22974956, PMID 23154212, PMID 23167441, PMID 23281637, PMID 23370547, PMID 23380861, PMID 23778649, PMID 24175245, PMID 24558049, PMID 24612768
2014 (1), 2015 (1), KL2TR002539 (1), R01DK093770 (1), R44DK066654 (1), R44DK078455 (1)