17 completed, 6 terminated, 3 recruiting, 2 active not recruiting. 30 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 30 | Completed 17, Terminated 6, Recruiting 3, Active not recruiting 2, Not yet recruiting 1, Unknown 1 |
| Phase 2 | 5 | Completed 2, Terminated 2, Not yet recruiting 1 |
Follow Kidney Failure: new trials by email Literature Review of Kidney Failure trials Research Report on Kidney Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Use of New Drug QRX-3 for Prevention and Treatment of Chronic Kidney Disease Progression QRX-3 - Chronic Kidney Diseases, Acute Kidney Injury | Phase 2 / Phase 3 | Not yet recruiting | Ebima Clifford Okundaye | 3000 | 2025-10-01 | 2025-09-08 |
| Multifactorial Intervention to Reduce Cardiovascular Disease in Type 1 Diabetes Aspirin tablet, Semaglutide, Sotagliflozin - Cardiovascular Diseases, Heart Failure | Phase 3 | Recruiting | Steno Diabetes Center Copenhagen | 2000 | 2024-07-01 | 2025-01-10 |
| Study of MB-102 (Relmapirazin) and the Use of the MediBeacon® Transdermal GFR Measurement System Using the TGFR Reusable Sensor With Disposable Adhesive Ring MB-102, MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR) - Kidney Diseases, Kidney Injury | Phase 3 | Completed | MediBeacon | 149 | 2023-03-20 | 2025-03-28 |
| Shingrix in Renal Transplant Recipients Shingrix - Kidney Transplant Recipient Response to Shingrix Vaccine, Kidney Failure | Phase 3 | Recruiting | University of Colorado, Denver | 132 | 2023-03-02 | 2026-04-08 |
| A Bioequivalence and Efficacy Study of MB-102 (Relmapirazin) in Chinese Participants MB-102 DMID, MB-102 OMID, MediBeacon Transdermal Glomerular Filtration Rate Measurement System (TGFR) - Kidney Diseases, Kidney Injury | Phase 3 | Completed | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | 121 | 2023-03-02 | 2024-01-02 |
| The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD Dapagliflozin 10 mg/day (oral), Placebo - Kidney Disease, Chronic, Renal Transplant Failure | Phase 3 | Active not recruiting | University Medical Center Groningen | 1750 | 2022-11-08 | 2026-10-08 |
| DAPAgliflozin for Renal Protection in Heart Transplant Recipients Dapagliflozin 10 mg, Placebo - Heart Transplant Failure, Kidney Failure | Phase 3 | Active not recruiting | Oslo University Hospital | 430 | 2022-06-08 | 2026-07-01 |
| Everolimus Plus Mycophenolic Acid for Kidney Preservation in Liver Transplant Recipients With Impaired Kidney Function Tacrolimus, Everolimus - Kidney Failure | Phase 3 | Terminated | Indiana University | 4 | 2019-12-19 | 2023-05-24 |
| Custodiol-N Solution Compared With Custodiol Solution in Organ Transplantation (Kidney, Liver and Pancreas) Custodiol-N Solution, Custodiol HTK Solution - Kidney Failure, Liver Failure, Chronic | Phase 3 | Recruiting | Dr. F. Köhler Chemie GmbH | 362 | 2019-05-23 | 2025-09-10 |
| Everolimus Monotherapy as Immunosuppression After Liver Transplant Tacrolimus, Everolimus - Kidney Failure | Phase 3 | Terminated | Indiana University | 14 | 2019-05-09 | 2023-05-23 |
| A Long-Term Safety Extension Trial of Ferric Citrate in Patients With End-Stage Renal Disease (ESRD) on Dialysis ferric citrate - End Stage Renal Disease, Kidney Failure | Phase 3 | Completed | Keryx Biopharmaceuticals | 168 | 2012-08-01 | 2016-07-13 |
| Comparison of Efficacy and Safety of Treatment With a Calcineurin Inhibitor (CNI)Versus a CNI-free Treatment in Renal Transplantation (CIME) cyclosporin + mycophenolate mofetil, everolimus + mycophenolate mofetil - Kidney Failure | Phase 3 | Completed | Centre Hospitalier Universitaire, Amiens | 88 | 2012-05-03 | 2026-06-12 |
| Safety and Efficacy Study of the Venous Window Needle Guide to Access Arteriovenous (AV)Fistulae Venous Window Needle Guide - End Stage Renal Disease, AV Fistula | Phase 2 / Phase 3 | Completed | Vital Access Corp. | 54 | 2011-12-01 | 2016-06-03 |
| A 58-Week Safety and Efficacy Trial of Ferric Citrate in Patients With ESRD on Dialysis ferric citrate, ca acetate, sevelamer carbonate, placebo - Hyperphosphatemia, Kidney Failure | Phase 3 | Completed | Keryx Biopharmaceuticals | 441 | 2010-10-01 | 2014-12-10 |
| Donor Simvastatin Treatment in Organ Transplantation Simvastatin 80mg, Control Rx - Heart Failure, Respiratory Failure | Phase 2 / Phase 3 | Completed | Helsinki University Central Hospital | 84 | 2010-06-01 | 2017-09-19 |
| Effect of Epoetin Beta on Renal Function Within 30 Days Following a Kidney Transplant epoetin beta (NeoRecormon ®) - Kidney Failure | Phase 3 | Completed | Centre Hospitalier Universitaire, Amiens | 108 | 2007-10-01 | 2016-04-28 |
| Dynepo Infrequent Dosing Study Dynepo (Epoetin delta), Dynepo - Anemia, Kidney Failure | Phase 3 | Terminated | Shire | 407 | 2006-10-30 | 2021-06-14 |
| Study Comparing Effect On Carotid Atherosclerosis Following Conversion From Tacrolimus To Sirolimus Post-Transplant In Kidney Transplant Patients tacrolimus, mycophenolate mofetil, prednisone - Atherosclerosis, Kidney Failure | Phase 3 | Terminated | Pfizer | 72 | 2006-04-01 | 2013-09-23 |
| COOL RCN: Cooling to Prevent Radiocontrast Nephropathy Reprieve Endovascular Temperature Therapy System - Renal Failure, Kidney Failure | Phase 2 / Phase 3 | Terminated | Radiant Medical | 400 | 2006-03-01 | 2008-08-05 |
| The Boston Scientific ACCESS Trial vascular access graft implantation - Renal Disease, Kidney Failure | Phase 2 / Phase 3 | Terminated | Maquet Cardiovascular | 149 | 2005-12-01 | 2012-06-27 |
Showing 20 of 30. Sign in to see all of them.
Renal Insufficiency (30) · Kidney Failure, Chronic (4) · Renal Insufficiency, Chronic (4) · Anemia (3) · Heart Failure (3) · Hyperphosphatemia (3) · Kidney Diseases (3) · Atherosclerosis (2) · Acute Kidney Injury (1) · Arteriovenous Fistula (1) · Bronchiolitis Obliterans Syndrome (1) · Cardiovascular Diseases (1) · Critical Illness (1) · Death (1) · Diabetes Mellitus, Type 1 (1)
Female Urogenital Diseases (30) · Female Urogenital Diseases and Pregnancy Complications (30) · Male Urogenital Diseases (30) · Urogenital Diseases (30) · Urologic Diseases (30) · Kidney Diseases (27) · Pathological Conditions, Signs and Symptoms (9) · Pathologic Processes (8) · Disease Attributes (7) · Cardiovascular Diseases (6) · Chronic Disease (6) · Heart Diseases (4) · Metabolic Diseases (4) · Nutritional and Metabolic Diseases (4) · Vascular Diseases (4)
Cyclosporine (4) · Tacrolimus (4) · Everolimus (3) · Aspirin (2) · Mycophenolic Acid (2) · Sirolimus (2) · calcium acetate (2) · dapagliflozin (2) · ferric citrate (2) · relmapirazin (2) · (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol (1) · Aspirin, Dipyridamole Drug Combination (1) · Bretschneider cardioplegic solution (1) · Clopidogrel (1) · Custodiol-N solution (1)
Centre Hospitalier Universitaire, Amiens (2) · Indiana University (2) · Keryx Biopharmaceuticals (2) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (2) · Wyeth is now a wholly owned subsidiary of Pfizer (2) · Centre Hospitalier Départemental (1) · Dr. F. Köhler Chemie GmbH (1) · Ebima Clifford Okundaye (1) · Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. (1) · Helsinki University Central Hospital (1) · Janssen-Ortho Inc., Canada (1) · Maquet Cardiovascular (1) · MediBeacon (1) · Melbourne Health (1) · Nabi Biopharmaceuticals (1)
United States (14) · France (5) · Netherlands (3) · Australia (2) · Austria (2) · Belgium (2) · Germany (2) · Italy (2) · Puerto Rico (2) · Spain (2) · Canada (1) · China (1) · Denmark (1) · Finland (1) · Israel (1)
Catherine Meyers, M.D. (2) · Chandrashekhar Kubal, MD (2) · John W Kusek, Ph.D. (2) · Julia B Lewis, MD (2) · Dong Sun (1) · Gregg Stone, MD (1) · Jaap J. Beutler, MD.PhD (1) · Karl B Lemstrom, MD, PhD (1) · Kevin Damman, MD, PhD (1)
PMID 18477783, PMID 35224730, PMID 36791280, PMID 39928546, PMID 40576086, PMID 16253719, PMID 17999759, PMID 19414832, PMID 19458364, PMID 20642691, PMID 21324193, PMID 24833247, PMID 26239948, PMID 31352795, PMID 34298589, PMID 37170711, PMID 39078403, PMID 40840822, PMID 41315742, PMID 41551843, PMID 41667648
U01DK058982 (2), 2017 (1), 2023 (1)