93 completed, 31 unknown, 17 recruiting, 10 terminated. 38 Phase 4, 30 Not applicable, 18 Phase 2, 18 Phase 3, 1 Early Phase 1.
Follow Hypertrophy, Left Ventricular: new trials by email Literature Review of Hypertrophy, Left Ventricular trials Research Report on Hypertrophy, Left Ventricular
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Therapeutic Implications of CMR Low Native T1 in Non-treated Non-hypertrophic Females With Fabry Disease (FD) Decision tree for initiating treatment - Fabry Disease | Not applicable | Not yet recruiting | University Hospital, Bordeaux | 60 | 2026-11-01 | 2026-10-14 |
| Detection of Cardiac Amyloidosis Using Right Ventricular Sensing Amplitude in Patients With Left Ventricular Hypertrophy Cardiac amyloidosis screening during CIED implantation - Cardiac Amyloidosis, Left Ventricular Hypertrophy | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 242 | 2026-09-01 | 2026-07-29 |
| Can Exercise Electrocardiography Discriminate Hypertensive Heart Disease From Obstructive Coronary Artery Disease? A Multimodality Imaging Study Obstructive Coronary Artery Disease, Left Ventricular Hypertrophy | Recruiting | University of Pisa | 30 | 2026-09-01 | 2026-09-29 | |
| Angiotensin Receptor Blocker After TAVR in Severe Aortic Stenosis With Left Ventricular Hypertrophy (ARBITAR) Angiotensin Receptor Blocker (ARB) - Transcatheter Aortic Valve Replacement (TAVR), Left Ventricular Hypertrophy | Phase 4 | Not yet recruiting | Seoul National University Hospital | 632 | 2026-08-15 | 2026-07-29 |
| AI-based Echocardiography for Detection of Cardiac Amyloidosis AI-based echocardiogram - Cardiac Amyloidosis, Heart Failure With Preserved Ejection Fraction (HFPEF) | Not applicable | Not yet recruiting | Germans Trias i Pujol Hospital | 200 | 2026-07-01 | 2026-06-12 |
| Study of LX2006 Gene Therapy in Friedreich Ataxia Cardiomyopathy LX2006, Usual Care - Friedreich Ataxia, Cardiomyopathy, Secondary | Phase 2 | Recruiting | Lexeo Therapeutics | 26 | 2026-06-25 | 2026-09-02 |
| Left Ventricular Hypertrophy in CKD Patients transthoracic echocardiography - Left Ventricular Hypertrophy | Not yet recruiting | Sohag University | 100 | 2026-01-15 | 2026-02-02 | |
| US Benchmarking Clinical Study HFpEF - Heart Failure With Preserved Ejection Fraction, HFmrEF | Recruiting | eMyosound SAS | 150 | 2025-09-16 | 2025-10-20 | |
| Evaluation of Left Ventricular Ejection Fraction Using an Accelerated Cardiac Cine-MRI Sequence With Deep Learning-based Image Reconstructions accelerated cardiac cine-MRI sequence - Left Ventricular Ejection Fraction, Cardiac Magnetic Resonance Imaging | Not applicable | Recruiting | Centre Hospitalier Universitaire, Amiens | 61 | 2025-08-05 | 2026-01-16 |
| Surgical Treatment of the Patients With Restrictive Phenotype of the Hypertrophic Cardiomyopathy Without LVOT Obstruction Surgical transaortic left ventricular cavity remodeling in patients with apical hypertrophic cardiomyopathy without left ventricular outflow tract obstruction - Apical Hypertrophic Cardiomyopathy | Enrolling by invitation | Petrovsky National Research Centre of Surgery | 50 | 2025-06-01 | 2025-07-02 | |
| Triple Combination Therapy (ARNI, SGLT2i, MRA) in Advanced HFpEF [ARNI + SGLTi + AMR], [SGLTi + previously taken RAAS blocker] - HFpEF, LVDD | Phase 2 | Recruiting | National Medical Research Center for Cardiology, Ministry of Health of Russian Federation | 50 | 2025-03-18 | 2026-04-24 |
| AI-Enabled Diagnosis and Prognosis of Hypertrophic Cardiomyopathy Hypertrophic Cardiomyopathy (HCM), Left Ventricular Hypertrophy | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 15000 | 2025-01-01 | 2025-12-04 | |
| Austrian Hypertrophic Cardiomyopathy Registry Hypertrophic Cardiomyopathy | Recruiting | Medical University of Graz | 1000 | 2024-03-08 | 2025-12-05 | |
| The COLchicine HEART Failure PRESERVED Trial (COLHEART-PRESERVED) Colchicine, Placebo - Heart Failure With Preserved Ejection Fraction | Phase 2 | Unknown | Tor Biering-Sørensen | 152 | 2024-01-18 | 2024-02-28 |
| Point-of-care Ultrasound and Treatment Disparities for Left Ventricular Hypertrophy Customized discharge and expedited referral instructions - Left Ventricular Hypertrophy | Not applicable | Completed | Yale University | 165 | 2023-10-15 | 2026-05-29 |
| A Study to Evaluate Accuracy and Validity of the Chang Gung ECG Abnormality Detection Software Chang Gung ECG Abnormality Detection Software - Long QT Syndrome, Sinus Bradycardia | Unknown | Chang Gung Memorial Hospital | 4306 | 2023-10-06 | 2024-01-11 | |
| Screening Patients With Fabry Disease in Patients With Hypertrophic Cardiomyopathy or Left Ventricular Hypertrophy Hypertrophic Cardiomyopathy, Left Ventricular Hypertrophy | Unknown | Qilu Hospital of Shandong University | 627 | 2023-10-01 | 2023-12-13 | |
| A Gene Therapy Study of RP-A501 in Male Patients With Danon Disease RP-A501 - Danon Disease | Phase 2 | Recruiting | Rocket Pharmaceuticals Inc. | 18 | 2023-09-05 | 2026-10-06 |
| Mineralocorticoid Receptor, Coronary Microvascular Function, and Cardiac Efficiency in Hypertension Eplerenone, Chlorthalidone, Potassium - Hypertension, Left Ventricular Hypertrophy | Phase 4 | Recruiting | Brigham and Women's Hospital | 75 | 2023-08-25 | 2026-04-06 |
| Effect of Azilsartan on Atrial Fibrillation in Patients With Hypertension Azilsartan or antihypertensive drugs other than ACEI, ARB or ARNI - Hypertension, Atrial Fibrillation | Phase 4 | Unknown | Beijing Tsinghua Chang Gung Hospital | 400 | 2023-06-01 | 2023-05-03 |
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Hypertension (48) · Heart Failure (19) · Aortic Valve Stenosis (16) · Cardiovascular Diseases (16) · Cardiomyopathy, Hypertrophic (15) · Kidney Failure, Chronic (14) · Hypertrophy (11) · Renal Insufficiency, Chronic (11) · Cardiomyopathies (9) · Heart Diseases (7) · Amyloid Neuropathies, Familial (6) · Fabry Disease (6) · Ventricular Dysfunction, Left (6) · Essential Hypertension (5)
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Valsartan (9) · Amlodipine (5) · Losartan (5) · Blood Specimen Collection (4) · Echocardiography (4) · Eplerenone (4) · Tadalafil (4) · Allopurinol (3) · Everolimus (3) · paricalcitol (3) · sacubitril and valsartan sodium hydrate drug combination (3) · Atenolol (2) · Colchicine (2) · Control Groups (2) · Electrocardiography (2)
National Heart, Lung, and Blood Institute (NHLBI) (5) · Massachusetts General Hospital (4) · Novartis Pharmaceuticals (4) · University of Dundee (4) · Assistance Publique - Hôpitaux de Paris (3) · Ege University (3) · Hospices Civils de Lyon (3) · Medical University of Vienna (3) · National Medical Research Center for Cardiology, Ministry of Health of Russian Federation (3) · Unity Health Toronto (3) · University of Aarhus (3) · Wake Forest University Health Sciences (3) · Washington University School of Medicine (3) · Andrea M. Isidori (2) · Assiut University (2)
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PMID 18591942, PMID 10450601, PMID 10678860, PMID 10908222, PMID 10940788, PMID 11208620, PMID 11422885, PMID 14630977, PMID 14744931, PMID 15253732, PMID 15647341, PMID 15772249, PMID 16093916, PMID 16253719, PMID 16376782, PMID 16966580, PMID 17389264, PMID 17494787, PMID 17921053, PMID 1798888, PMID 18404673, PMID 18456674, PMID 18458174, PMID 19153263, PMID 19332468, PMID 19515473, PMID 19528362, PMID 19687350, PMID 19933939, PMID 20001655, PMID 20016520, PMID 20038754, PMID 20167684, PMID 20411620, PMID 20589977, PMID 20601389, PMID 21193690, PMID 21239405, PMID 21242674, PMID 21304095, PMID 21330484, PMID 21353251, PMID 21358415, PMID 21388319, PMID 21632446, PMID 21720264, PMID 21746765, PMID 22068434, PMID 22068435, PMID 22172590
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