111 completed, 24 unknown, 23 terminated, 18 recruiting. 51 Not applicable, 30 Phase 3, 29 Phase 2, 29 Phase 4, 19 Phase 1.
Follow Kidney Failure: new trials by email Literature Review of Kidney Failure trials Research Report on Kidney Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Tenofovir Exposures in Advanced Kidney Disease Study Plasma sampling for tenofovir and emtricitabine, Descovy - Tenofovir, Tenofovir Alafenamide Fumarate | Not yet recruiting | King's College Hospital NHS Trust | 50 | 2026-11-01 | 2026-09-10 | |
| Predictors of Rapid CKD Progression Chronic Kidney Diseases, Kidney Failure | Not yet recruiting | Assiut University | 190 | 2026-09-01 | 2026-09-03 | |
| Clinical Characteristics and In-Hospital Outcomes of Critically Ill Patients Receiving Hemodialysis or Continuous Venovenous Hemodiafiltration in the Emergency Department Hemodialysis (HD), Continuous Venovenous Hemodiafiltration (CVVHDF) - Acute Kidney Injury, Kidney Failure, Acute | Not yet recruiting | Antalya Health Sciences University | 150 | 2026-08-10 | 2026-08-14 | |
| Study of the Effect of Haemodialysis on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone/Dapagliflozin Balcinrenone/dapagliflozin - Kidney Failure | Phase 1 | Completed | AstraZeneca | 10 | 2026-08-06 | 2026-10-20 |
| Dialysate Cooling for the Preservation of Cognitive Function in People Receiving Haemodialysis Dialysis cooling - Haemodialysis, Kidney Failure | Not applicable | Not yet recruiting | University Hospitals of Derby and Burton NHS Foundation Trust | 356 | 2026-04-01 | 2026-02-03 |
| Kidney Transplant Improvement Through New Exercise Training to Increase Capacity Exercise Rehabilitation Program with Physical Activity Tracker, Active control - Chronic Kidney Disease 5D, Chronic Kidney Disease Stage 5 | Not applicable | Recruiting | University of Pennsylvania | 60 | 2026-03-24 | 2026-05-06 |
| Renal and Hepatic Abnormal Doppler Patterns in Trauma Point of care ultrasound - Trauma (Including Fractures), Trauma Patients | Recruiting | Azienda Usl di Bologna | 350 | 2026-03-01 | 2026-03-25 | |
| Older Kidney Patient Optimisation Pretransplant Kidney transplant-specific comprehensive geriatric assessment - Kidney Disease, Kidney Failure | Not applicable | Not yet recruiting | Guy's and St Thomas' NHS Foundation Trust | 50 | 2026-02-02 | 2026-02-19 |
| Comparing Hepatitis B Vaccination Schedules in Patients on Hemodialysis Recombinant Hepatitis B Vaccine - 3-Dose Schedule, Recombinant Hepatitis B Vaccine - 4-Dose Schedule - Hepatitis B, ESRD (End Stage Renal Disease) | Not applicable | Completed | Jinnah Hospital | 104 | 2025-12-10 | 2026-08-25 |
| Hypothermic Machine Perfusion With Omnisol of Deceased Donor Kidneys Prior to Transplantation Omnisol organ preservation solution - Kidney Transplant, Kidney Failure | Not applicable | Recruiting | Vivalyx GmbH | 15 | 2025-11-17 | 2026-08-28 |
| A Study of Maribavir in Adults With Kidney Failure Who Have a Cytomegalovirus (CMV) Infection After Transplantation No Intervention - Cytomegalovirus (CMV), Kidney Disease | Recruiting | Takeda | 10 | 2025-11-03 | 2025-12-16 | |
| Worldwide Assessment of Deceased Donor Kidney Utilization Kidney Failure, Kidney Transplant | Enrolling by invitation | Paris Translational Research Center for Organ Transplantation | 300000 | 2025-11-01 | 2026-01-14 | |
| Use of New Drug QRX-3 for Prevention and Treatment of Chronic Kidney Disease Progression QRX-3 - Chronic Kidney Diseases, Acute Kidney Injury | Phase 2 / Phase 3 | Not yet recruiting | Ebima Clifford Okundaye | 3000 | 2025-10-01 | 2025-09-08 |
| STarting incrEmental Prescription of Peritoneal Dialysis Incremental PD, Full dose PD - Peritoneal Dialysis (PD), Kidney Failure | Not applicable | Recruiting | The University of Queensland | 224 | 2025-09-19 | 2026-10-15 |
| Levocarnitine for Reducing ESA Requirements in Hemodialysis Patients With Renal Anemia Levocarnitine Injection, Usual ESA-Based Anemia Care - Anemia, Kidney Failure | Phase 4 | Not yet recruiting | Shaikh Zayed Hospital, Lahore | 94 | 2025-09-15 | 2025-09-12 |
| A High Protein Egg White Pudding for People With Kidney Failure (HiPE KF) Egg white protein pudding, : Ensure Plus - Kidney Failure, Frailty | Not applicable | Recruiting | Seven Oaks Hospital Chronic Disease Innovation Centre | 54 | 2025-07-25 | 2026-04-22 |
| CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk Ex Vivo CRISPR-Cas9 Gene Editing of Donor Kidney, Kidney Transplantation with Standard Care - End-Stage Renal Disease, End Stage Renal Disease on Dialysis | Phase 1 / Phase 2 | Recruiting | AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC | 90 | 2025-06-01 | 2025-07-08 |
| Tolerance Through Mixed Chimerism (Sip-Tego) Combined Kidney/Bone Marrow Transplant, Donation of Kidney / Bone Marrow, Conditioning Regimen (Rituxan, Siplizumab (or ATGAM), Cyclophosphamide, Tegoprubart) - Kidney Failure, Transplant Recipient (Kidney) | Early Phase 1 | Active not recruiting | Tatsuo Kawai, MD, PhD | 12 | 2025-05-31 | 2026-09-25 |
| Amino Acid Loss During Continuous Renal Replacement Therapy Renal Insufficiency, Kidney Failure | Recruiting | Medical University of Vienna | 30 | 2025-02-08 | 2025-05-25 | |
| Deceased Donor Bladder or Combined Kidney-bladder Transplantation: a Phase 0 First-in-human Study Bladder Transplantation, Combined Kidney and Bladder Transplantation - Bladder Disease, Bladder, Neurogenic | Not applicable | Recruiting | University of California, Los Angeles | 5 | 2025-02-01 | 2025-02-12 |
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Renal Insufficiency (201) · Kidney Failure, Chronic (32) · Kidney Diseases (29) · Renal Insufficiency, Chronic (26) · Heart Failure (10) · Acute Kidney Injury (9) · Arteriovenous Fistula (8) · Anemia (6) · Diabetes Mellitus (5) · Liver Failure (5) · Bronchiolitis Obliterans Syndrome (4) · Edema (4) · Fibrosis (4) · Graft vs Host Disease (4) · Hyperphosphatemia (4)
Female Urogenital Diseases (201) · Female Urogenital Diseases and Pregnancy Complications (201) · Male Urogenital Diseases (201) · Urogenital Diseases (201) · Urologic Diseases (200) · Kidney Diseases (172) · Pathological Conditions, Signs and Symptoms (74) · Pathologic Processes (62) · Disease Attributes (49) · Chronic Disease (46) · Cardiovascular Diseases (27) · Renal Insufficiency, Chronic (20) · Vascular Diseases (18) · Metabolic Diseases (16) · Nutritional and Metabolic Diseases (16)
Sirolimus (12) · Tacrolimus (10) · Cyclosporine (7) · Mycophenolic Acid (6) · Kidney Transplantation (5) · Everolimus (4) · dapagliflozin (4) · Alemtuzumab (3) · Cyclophosphamide (3) · Rituximab (3) · Saline Solution (3) · thymoglobulin (3) · Aspirin (2) · Erythropoietin (2) · Exercise (2)
Wyeth is now a wholly owned subsidiary of Pfizer (10) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (6) · Massachusetts General Hospital (4) · Centre Hospitalier Universitaire, Amiens (3) · Indiana University (3) · National Institute of Allergy and Infectious Diseases (NIAID) (3) · Seoul National University Hospital (3) · Universitaire Ziekenhuizen KU Leuven (3) · University College, London (3) · George Washington University (2) · Helsinki University Central Hospital (2) · Johns Hopkins University (2) · Keryx Biopharmaceuticals (2) · London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's (2) · Medical University of Vienna (2)
United States (74) · United Kingdom (15) · Canada (13) · France (12) · Belgium (9) · China (8) · Australia (7) · Germany (7) · Italy (7) · Austria (6) · Netherlands (6) · Spain (6) · Turkey (Türkiye) (6) · Switzerland (5) · Denmark (4)
Byung-Hee Oh, M.D., Ph.D. (3) · Sang-Ho Jo, M.D. (3) · Catherine Meyers, M.D. (2) · Chandrashekhar Kubal, MD (2) · Hyo-Soo Kim, M.D.,Ph.D. (2) · John W Kusek, Ph.D. (2) · Julia B Lewis, MD (2) · Adam G McLean, FRCP, DPhil (1) · Akinlolu O. Ojo, MD, PhD, MBA (1) · Alaattin Yildiz, Professor of Medicine, MD (1)
PMID 36791280, PMID 40576086, PMID 18477783, PMID 24195547, PMID 35018639, PMID 35224730, PMID 39928546, PMID 16253719, PMID 16949481, PMID 17359508, PMID 17565313, PMID 17608835, PMID 17999759, PMID 18294484, PMID 18513531, PMID 18704002, PMID 18922992, PMID 19261823, PMID 19414832, PMID 19443638, PMID 19458364, PMID 19681815, PMID 19762492, PMID 19851652, PMID 20145526, PMID 20526235, PMID 20634326, PMID 20642691, PMID 20829423, PMID 20943783, PMID 21118736, PMID 21195518, PMID 21324193, PMID 21354681, PMID 21564530, PMID 21836540, PMID 22152013, PMID 22193388, PMID 22742720, PMID 22776430, PMID 23136888, PMID 23137211, PMID 23325011, PMID 23803600, PMID 23903014, PMID 23949799, PMID 24011252, PMID 24127489, PMID 24262029, PMID 24528505
U01DK058982 (2), 2005 (1), 2017 (1), 2023 (1), 5RC2DK122397 (1), M01RR000042 (1), R01DK111966 (1), R01DK131265 (1), R01DK144325 (1), U01DK116040 (1), U01DK116041 (1)