10 completed. 10 Phase 1, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 10 |
| Phase 2 | 5 | Completed 5 |
Follow Kidney Failure: new trials by email Literature Review of Kidney Failure trials Research Report on Kidney Failure
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Study of the Effect of Haemodialysis on the Pharmacokinetics, Safety, and Tolerability of Balcinrenone/Dapagliflozin Balcinrenone/dapagliflozin - Kidney Failure | Phase 1 | Completed | AstraZeneca | 10 | 2026-08-06 | 2026-10-20 |
| Safety, Tolerability, and Feasibility of Empagliflozin Therapy in Dialysis-dependent ESKD Empagliflozin, Placebo - End-stage Kidney Disease, Kidney Disease, Chronic | Phase 1 | Completed | University of Utah | 62 | 2023-03-21 | 2026-10-30 |
| Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus EP547, Placebo - Pruritus, Cholestasis | Phase 1 | Completed | Escient Pharmaceuticals, Inc | 89 | 2020-09-07 | 2025-08-08 |
| A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function BMS-986231 - Myocardial Failure, Cardiac Failure | Phase 1 | Completed | Bristol-Myers Squibb | 48 | 2018-03-15 | 2019-09-11 |
| C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI C1 Esterase Inhibitor, Placebo - End Stage Renal Disease, Kidney Failure | Phase 1 / Phase 2 | Completed | Cedars-Sinai Medical Center | 70 | 2014-09-01 | 2018-06-25 |
| Quantitative Mass Transfer of SFP-iron From Dialysate to Blood in CKD-HD Patients Soluble Ferric Pyrophosphate, Placebo - Kidney Failure | Phase 1 / Phase 2 | Completed | Rockwell Medical Technologies, Inc. | 12 | 2013-07-01 | 2015-02-16 |
| Mesenchymal Stem Cells After Renal or Liver Transplantation Mesenchymal Stem Cells - Liver Failure, Kidney Failure | Phase 1 / Phase 2 | Completed | University of Liege | 40 | 2012-02-01 | 2022-06-14 |
| Validation of Serum Creatinine Dosage and Renal Clearance Calculation of inuline clearance, Measuring serum creatinine - Kidney Failure | Phase 1 | Completed | University Hospital, Ghent | 30 | 2006-05-01 | 2011-06-02 |
| Using Donor Stem Cells and Alemtuzumab to Prevent Organ Rejection in Kidney Transplant Patients Alemtuzumab, Mycophenolate mofetil, Sirolimus - Kidney Transplantation, Kidney Disease | Phase 1 / Phase 2 | Completed | University of Miami | 9 | 2004-09-01 | 2012-10-02 |
| Acetylcysteine in the Prevention of Renal Failure After Bypass Surgery N-Acetylcysteine - Kidney Failure | Phase 1 / Phase 2 | Completed | Minneapolis Veterans Affairs Medical Center | 102 | 2003-04-01 | 2007-09-19 |
Renal Insufficiency (10) · Kidney Diseases (2) · Kidney Failure, Chronic (2) · Renal Insufficiency, Chronic (2) · Bronchiolitis Obliterans Syndrome (1) · Cholestasis (1) · Delayed Graft Function (1) · Fibrosis (1) · Heart Failure (1) · Liver Diseases (1) · Liver Failure (1) · Liver Failure, Acute (1) · Neoplasms (1) · Pruritus (1)
Female Urogenital Diseases (10) · Female Urogenital Diseases and Pregnancy Complications (10) · Male Urogenital Diseases (10) · Urogenital Diseases (10) · Urologic Diseases (10) · Kidney Diseases (8) · Pathological Conditions, Signs and Symptoms (4) · Pathologic Processes (3) · Chronic Disease (2) · Digestive System Diseases (2) · Disease Attributes (2) · Bile Duct Diseases (1) · Biliary Tract Diseases (1) · Bronchial Diseases (1) · Bronchiolitis (1)
Acetylcysteine (1) · Alemtuzumab (1) · Complement C1 Inhibitor Protein (1) · Kidney Transplantation (1) · Mycophenolic Acid (1) · Saline Solution (1) · Sirolimus (1) · Sodium Chloride (1) · Tacrolimus (1) · dapagliflozin (1) · empagliflozin (1) · spleen fibrinolytic proteinase (human) (1)
AstraZeneca (1) · Bristol-Myers Squibb (1) · Cedars-Sinai Medical Center (1) · Escient Pharmaceuticals, Inc (1) · Minneapolis Veterans Affairs Medical Center (1) · Rockwell Medical Technologies, Inc. (1) · University Hospital, Ghent (1) · University of Liege (1) · University of Miami (1) · University of Utah (1)
United States (6) · Belgium (2) · Australia (1) · Czechia (1) · New Zealand (1) · Poland (1)
Arjan Van der Tol, MD (1) · Ashley Vo, PharmD (1) · George W. Burke, III, MD (1) · Raymond D Pratt, MC FACP (1) · Raymond Van Holder, MD, PhD (1) · Selcuk Adabag, MD (1) · Stanley C Jordan, MD (1) · Yves Beguin, MD, PhD (1)
PMID 18513531, PMID 23903014, PMID 28284916
R01DK131265 (1)