39 completed, 15 recruiting, 11 unknown, 6 not yet recruiting. 37 Not applicable, 7 Phase 4, 2 Phase 3, 1 Early Phase 1.
Follow Intraoperative Hypotension: new trials by email Literature Review of Intraoperative Hypotension trials Research Report on Intraoperative Hypotension
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Feasibility Study of E-Fusion Vasopressor Titration-Assist During Multi-Level Spine Surgery E-Fusion Vasopressor Titration-Assist - Intraoperative Hypotension | Not applicable | Not yet recruiting | Autonomous Healthcare, Inc. | 10 | 2027-03-01 | 2026-09-25 |
| Intelligent Classification of Intraoperative Hemodynamic Phenotypes Based on CADFlow Doppler Monitoring Ultrasound, Machine Learning | Not yet recruiting | Shanghai 6th People's Hospital | 440 | 2026-11-01 | 2026-10-27 | |
| Effect of Remimazolam Versus Propofol Total Intravenous Anesthesia on Intraoperative Hemodynamic Stability in Patients Undergoing Thoracic or Abdominal Endovascular Aortic Repair Remimazolam Besylate, propofol - Aortic Aneurysm, Thoracoabdominal, Aortic Aneurysm, Abdominal | Phase 4 | Recruiting | Seoul National University Hospital | 44 | 2026-10-01 | 2026-10-29 |
| Internal Jugular Vein Ultrasound and Acute Kidney Injury After Abdominal Surgery Internal Jugular Vein Ultrasound Assesment - Intraoperative Hypotension, Jugular Veins | Recruiting | Tîrgu Mureș Emergency Clinical County Hospital, Romania | 150 | 2026-09-07 | 2026-09-10 | |
| Superiority of Phenylephrine Versus Norepinephrine in Complex Spine Surgery (SPiNeS) Phenylephrine hydrochloride infusion, Norepinephrine bitartrate infusion - Spine Surgery, Intraoperative Hypotension | Phase 4 | Not yet recruiting | Mayo Clinic | 50 | 2026-09-01 | 2026-09-02 |
| Remimazolam Versus Propofol for Maintenance of Anaesthesia During Major Hepatectomy Under Low Central Venous Pressure Remimazolam, Propofol - Intraoperative Hypotension, Hepatectomy | Phase 4 | Recruiting | Beijing Tsinghua Chang Gung Hospital | 224 | 2026-09-01 | 2026-11-04 |
| Dural Sac Area-Guided Spinal Anesthesia Dosing for TURP DSCSA-Guided Individualized Spinal Anesthesia Dosing, Bupivacaine, Fentanyl (FEN) - Intraoperative Hypotension, Spinal Aneshtesia | Not applicable | Enrolling by invitation | Istanbul University | 60 | 2026-08-27 | 2026-10-01 |
| Maintaining Intraoperative Mean Arterial Pressure at 85 mmHg or Higher to Reduce Postoperative Delirium in Older Patients With Arterial Hypertension Having Non-cardiac Surgery MAP at 85 mmHg or higher (intervention group), MAP at 65 mmHg or higher (control group) - Postoperative Delirium (POD), Intraoperative Hypotension | Not applicable | Recruiting | Universitätsklinikum Hamburg-Eppendorf | 3432 | 2026-08-21 | 2026-08-25 |
| PRO STRESS Trial: Proactive Low-Dose Norepinephrine to Reduce Intraoperative Fluid Administration in Patients at High-Risk for Postoperative Pulmonary Complications Undergoing Laparoscopic Abdominal Surgery Norepinephrine, Placebo - Intraoperative Hypotension, Postoperative Pulmonary Complications (PPCs) | Not applicable | Not yet recruiting | Suez Canal University | 130 | 2026-07-15 | 2026-07-13 |
| Internal Jugular Vein Collapsibility Index as a Predictor of Hypotension Internal Jugular Vein Collapsibility Index - Intraoperative Hypotension | Recruiting | Ain Shams University | 70 | 2026-07-11 | 2026-07-20 | |
| Remimazolam Versus Midazolam for General Anesthesia Induction in Elderly Patients Undergoing Non-Cardiac Surgery General Anesthesia, Aged | Recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 1000 | 2026-06-15 | 2026-08-05 | |
| AI-Assisted Blood Pressure Control During Anesthesia Device: AI Clinical Decision Support System, Procedure: Standard of Care Anesthesia - Intraoperative Hypotension, Hemodynamic Instability | Not applicable | Not yet recruiting | Beijing Tsinghua Chang Gung Hospital | 40 | 2026-06-01 | 2026-04-06 |
| Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) for Perioperative Hemodynamic Optimization in Patients Under General Anesthesia Acumen IQ sensor with Hypotension Prediction Index (HPI) and Assisted Fluid Management (AFM) software, Conventional Intraoperative Hemodynamic management - Intraoperative Hypotension | Not applicable | Recruiting | National and Kapodistrian University of Athens | 100 | 2026-03-15 | 2026-04-20 |
| Machine Learning-Assisted Management of Intraoperative Hypotension for Personalized Treatment Intraoperative Hypotension, Perioperative Care | Completed | Nevsehir Public Hospital | 50 | 2026-03-03 | 2026-11-03 | |
| Oscillometric Versus Intraarterial Blood Pressure Monitoring During Robot-Assisted Prostatectomy Oscillometric blood pressure monitoring, Intraarterial blood pressure monitoring - Intraoperative Hypotension | Not applicable | Recruiting | University of Hamburg-Eppendorf | 210 | 2026-01-29 | 2026-02-02 |
| Femoral Vein Diameter to Predict Intraoperative Hypotension in Geriatric Patients Undergoing Orthopedic Surgery Under Spinal Anesthesia Measurement of Femoral Vein Diameter - Femoral Vein Diameter, Intraoperative Hypotension | Recruiting | Cairo University | 43 | 2025-12-01 | 2026-01-14 | |
| Impact of Intraoperative Blood Pressure Components on Postoperative AKI: A Phenotype-Stratified Analysis Postoperative Acute Kidney Injury, Intraoperative Hypotension | Active not recruiting | Lanyue Zhu | 44504 | 2025-09-09 | 2026-08-06 | |
| Intrathecal Dexmedetomidine 5 mcg Versus 10 mcg With Bupivacaine for Infra-umbilical Surgery Dexmedetomidine 5 micrograms (intrathecal), Dexmedetomidine 10 micrograms (intrathecal), Hyperbaric bupivacaine 0.5% - Spinal Anesthesia, Intraoperative Hypotension | Phase 4 | Completed | Hussain Aziz Bhatti | 544 | 2025-08-01 | 2026-11-10 |
| Hemodynamic Effects of Intradermal Methylene Blue During Breast Surgery Under General Anesthesia Methylene Blue, Standard Surgical Care Without Dye - Breast Cancer, Breast Surgery | Completed | Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital | 220 | 2025-07-01 | 2026-04-30 | |
| Noradrenaline Versus Standard Blood Pressure Management for Perioperative Hypotension in Non-cardiac Surgery noradrenaline infusion for management blood pressure, standard blood pressure management - Blood Pressure Management, Intraoperative Hypotension | Phase 3 | Recruiting | Jagiellonian University | 750 | 2025-06-24 | 2026-09-23 |
Showing 20 of 75. Sign in to see all of them.
Hypotension (10) · Acute Kidney Injury (9) · Postoperative Complications (7) · Intraoperative Complications (6) · Emergence Delirium (2) · Hip Fractures (2) · Pain, Postoperative (2) · Postoperative Cognitive Complications (2) · Acute Pain (1) · Agnosia (1) · Anxiety Disorders (1) · Aortic Aneurysm, Abdominal (1) · Aortic Aneurysm, Thoracoabdominal (1) · Blood Loss, Surgical (1) · Bradycardia (1)
Pathologic Processes (19) · Pathological Conditions, Signs and Symptoms (19) · Cardiovascular Diseases (14) · Vascular Diseases (14) · Female Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (9) · Kidney Diseases (9) · Male Urogenital Diseases (9) · Renal Insufficiency (9) · Urogenital Diseases (9) · Urologic Diseases (9) · Mental Disorders (5) · Nervous System Diseases (5) · Signs and Symptoms (5) · Neurologic Manifestations (4)
Norepinephrine (4) · Phenylephrine (3) · Propofol (3) · remimazolam (3) · Bupivacaine (2) · Vasoconstrictor Agents (2) · Anesthesia, General (1) · Anesthesia, Spinal (1) · Angiotensin II (1) · Balanced Anesthesia (1) · Cholangiopancreatography, Endoscopic Retrograde (1) · Coloring Agents (1) · Control Groups (1) · Dexamethasone (1) · Ephedrine (1)
Universitätsklinikum Hamburg-Eppendorf (6) · Seoul National University Hospital (4) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (3) · Beijing Tsinghua Chang Gung Hospital (2) · Lviv National Medical University (2) · Nanjing First Hospital, Nanjing Medical University (2) · Peking Union Medical College Hospital (2) · Peking University First Hospital (2) · Second Affiliated Hospital, Zhejiang University, School of Medicine (2) · Acibadem University (1) · Ain Shams University (1) · Ankara City Hospital Bilkent (1) · Assistance Publique - Hôpitaux de Paris (1) · Attikon Hospital (1) · Autonomous Healthcare, Inc. (1)
China (16) · Germany (9) · Turkey (Türkiye) (7) · United States (6) · Italy (5) · South Korea (5) · Egypt (4) · Greece (3) · Netherlands (3) · Sweden (3) · Poland (2) · Taiwan (2) · Ukraine (2) · United Kingdom (2) · Finland (1)
Chang-Hoon Koo (2) · Dong-Xin Wang, MD, PhD (2) · Maksym Barsa (2) · Max Bell, MD, PhD (2) · Alexandre Joosten, MD PhD (1) · Antonio Messina (1) · Ashish Khanna, MD (1) · Behnood Gholami, PhD (1) · Bernd Saugel, M.D. (1) · Bernd Saugel, Prof. Dr. (1) · Christian Zoellner, Professor (1) · D.P. Veelo, Dr (1) · Eric Deloso, MD (1)
PMID 32065827, PMID 39576150, PMID 10334155, PMID 21045639, PMID 21705869, PMID 22661747, PMID 23835589, PMID 25524443, PMID 26162676, PMID 26181335, PMID 26578397, PMID 27683581, PMID 27792044, PMID 28438121, PMID 29742967, PMID 29750699, PMID 29779129, PMID 29894315, PMID 30896602, PMID 31053082, PMID 31508443, PMID 31601239, PMID 31784852, PMID 32960954, PMID 33446404, PMID 33901281, PMID 34034957, PMID 34775533, PMID 34945177, PMID 35054083, PMID 35256251, PMID 35610620, PMID 35654467, PMID 36174389, PMID 36397173, PMID 36717143, PMID 37119322, PMID 37130670, PMID 37577293, PMID 37667479, PMID 38925990, PMID 39050403, PMID 39052844, PMID 39116013, PMID 39411994, PMID 40012367, PMID 40410627, PMID 40778974, PMID 41034767, PMID 41076588
2023 (2), 2025 (1), R43HL187059 (1)