9 unknown, 7 completed, 4 not yet recruiting, 1 enrolling by invitation. 9 Not applicable, 3 Phase 2, 3 Phase 4, 1 Early Phase 1, 1 Phase 3.
Follow Intracranial Hemorrhage, Hypertensive: new trials by email Literature Review of Intracranial Hemorrhage, Hypertensive trials Research Report on Intracranial Hemorrhage, Hypertensive
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Yiqi Huayu Jiedu Therapy for Non-Surgical Supratentorial Hypertensive Intracerebral Hemorrhage Yiqi Huayu Jiedu Mixture Intervention, The placebo - Intracranial Hemorrhage, Hypertensive | Not applicable | Not yet recruiting | Guangzhou University of Traditional Chinese Medicine | 902 | 2026-08-01 | 2026-05-12 |
| Efficacy and Safety of Antihypertensive Treatment With Mobile Stroke Units in Ultra-Early Intracerebral Hemorrhage Mobile Stroke Unit Management, Standard Management - Nervous System Diseases, Cerebrovascular Disorders | Not applicable | Not yet recruiting | Xuanwu Hospital, Beijing | 706 | 2026-06-01 | 2026-06-24 |
| Comparison of Post-Craniotomy Blood Pressure Targets Target SBP <160mmHg, Target SBP <140 mmHg - Intracranial Hemorrhage, Hypertensive, Craniotomy Tumor Removal Surgery | Not applicable | Enrolling by invitation | Vanderbilt University Medical Center | 500 | 2026-04-15 | 2026-04-21 |
| A Multicenter, Randomized, Double-blind, Placebo-controlled Trial on the Treatment of Hypertensive Intracerebral Hemorrhage With Naoxuekang Dropping Pills Naoxuekang Dropping Pills, Naoxuekang Matching Placebo - Hypertensive Intracerebral Hemorrhage, Cerebral Small Vessel Diseases | Phase 2 | Not yet recruiting | Beijing Tiantan Hospital | 1950 | 2025-10-10 | 2025-10-01 |
| Efficacy and Safety Study of Urapidil Alone or With Esmolol in Treating Acute Hypertensive Intracerebral Hemorrhage Urapidil, Urapidil and Esmolol - Hypertensive Intracerebral Hemorrhage | Not yet recruiting | Qianfoshan Hospital | 600 | 2024-11-01 | 2024-10-10 | |
| Ketamine for Sedation in Severe Traumatic Brain Injury Ketamine with propofol, Standard of Care propofol, fentanyl, dexmedetomidine, morphine, hydromorphone, midazolam, or lorazepam - Severe Traumatic Brain Injury, Intracranial Hypertension | Phase 4 | Suspended | Henry M. Jackson Foundation for the Advancement of Military Medicine | 50 | 2024-09-23 | 2025-07-14 |
| Multiomic Analysis of Traumatic Brain Injury and Hypertension Intracranial Hemorrhage Lesion Tissue Type of disease - Brain Injury Traumatic Severe, Intracranial Hemorrhage, Hypertensive | Unknown | RenJi Hospital | 10 | 2023-04-01 | 2023-05-03 | |
| Bleeding Intracerebral Hemorrhage With Early Invasive Intracranial Pressure Monitoring Trial Parenchymal Intracranial pressure monitor, Treatment based on clinical and imaging observations - Cerebral Hemorrhage, Hypertensive, Intracranial Hypertension | Not applicable | Completed | Xiangya Hospital of Central South University | 193 | 2022-11-15 | 2025-09-08 |
| Robotic Assisted Evacuation of Subacute and Chronic Supratentorial Deep Hypertensive Intracerebral Hemorrhage Robotic Assisted Evacuation - Hypertensive Intracerebral Hemorrhage | Not applicable | Unknown | Shanghai Changzheng Hospital | 428 | 2022-09-01 | 2022-08-10 |
| Coach Pilot Study: Assessing Cognitive Function and Related Small Vessel Disease Markers After Intracerebral Hemorrhage Cerebral Amyloid Angiopathy, Intracerebral Hemorrhage | Terminated | Leiden University Medical Center | 2 | 2022-04-03 | 2024-11-18 | |
| Acute Hypertensive Cerebral Hemmorrhage Surgery The Neuroendoscopic, Trans-occipital Approach Evacuation of Acute Hypertensive Cerebral Hemmorrhage Combined Low-drainage Surgery, Endoscopic Evacuation of Acute Hypertensive Intracerebral Hemorrhage via Trans-frontal keyhole approach - Hypertensive Intracerebral Hemorrhage | Not applicable | Unknown | Shanghai Changzheng Hospital | 1000 | 2022-01-01 | 2021-07-12 |
| Fingolimod as a Treatment of Cerebral Edema After Intracerebral Hemorrhage Fingolimod, Placebo, Open-label Fingolimod - Intracerebral Hemorrhage, Cerebral Edema | Early Phase 1 | Completed | Wake Forest University Health Sciences | 28 | 2020-08-07 | 2025-01-23 |
| Neurological Outcomes of Primary Intracerebral Haemorrhage Intracranial Hemorrhage, Hypertensive | Unknown | University Hospital, Grenoble | 40 | 2019-04-30 | 2019-06-24 | |
| Start or STop Anticoagulants Randomised Trial (SoSTART) Apixaban, Rivaroxaban, Edoxaban - Intracranial Hemorrhages, Intracranial Hemorrhage, Hypertensive | Phase 3 | Completed | University of Edinburgh | 203 | 2018-03-28 | 2022-04-08 |
| Clinical Evaluation of Removing Blood Stasis Therapy in Treating Acute Cerebral Hemorrhage Safety and Efficacy AICH-PXZY, AICH-without PXZY, AICH-placebo - Intracerebral Hemorrhage, Hypertensive, Traditional Chinese Medicine | Phase 4 | Unknown | Guangzhou University of Traditional Chinese Medicine | 306 | 2017-11-01 | 2017-11-27 |
| Minimally-invasive Surgery Versus Craniotomy in Patients With Supratentorial Hypertensive Intracerebral Hemorrhage Endoscopic Evacuation, Stereotactic Aspiration, Craniotomy - Intracranial Hemorrhage, Hypertensive | Not applicable | Completed | Chinese PLA General Hospital | 733 | 2016-07-01 | 2023-02-22 |
| Intravenous Immunoglobulin for Acute Intracranial Hemorrhage Immunoglobulin Therapy, Standard management - Intracranial Hemorrhage, Hypertensive | Phase 2 | Unknown | Wei Wang | 60 | 2016-06-01 | 2016-05-25 |
| Dose-effect Relationship of Rt-PA on ICH Evacuation YL-1 type of intracranial hematoma puncture needle, rt-PA - Hypertensive Intracerebral Hemorrhage | Phase 2 | Unknown | Tongji Hospital | 108 | 2015-06-01 | 2015-06-16 |
| Clinical Study on the Treatment of Hypertensive Intracerebral Hemorrhage With Panax Notoginseng Saponin Panax Notoginseng Saponins - Hematoma Absorption and Neurological Function Recovery | Phase 4 | Completed | The First People's Hospital of Jingzhou | 90 | 2014-05-01 | 2016-12-21 |
| MRI for the Early Evaluation of Acute Intracerebral Hemorrhage MRI Scan with the specified sequences below: - Cerebral Hemorrhage, Intracranial Arteriovenous Malformations | Completed | Bispebjerg Hospital | 60 | 2012-04-01 | 2021-01-28 |
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Cerebral Hemorrhage (6) · Brain Edema (2) · Brain Injuries (2) · Brain Injuries, Traumatic (2) · Cerebral Small Vessel Diseases (2) · Hemorrhagic Stroke (2) · Intracranial Hemorrhages (2) · Intracranial Hypertension (2) · Stroke (2) · Atrial Fibrillation (1) · Atrial Flutter (1) · Brain Neoplasms (1) · Bronchiolitis Obliterans Syndrome (1) · Cardiovascular Diseases (1)
Brain Diseases (23) · Central Nervous System Diseases (23) · Cardiovascular Diseases (22) · Cerebrovascular Disorders (22) · Nervous System Diseases (22) · Vascular Diseases (22) · Intracranial Hemorrhages (21) · Pathologic Processes (9) · Pathological Conditions, Signs and Symptoms (9) · Hemorrhage (7) · Craniocerebral Trauma (5) · Trauma, Nervous System (5) · Wounds and Injuries (5) · Brain Injuries (2) · Intracranial Arterial Diseases (2)
Suction (3) · Conservative Treatment (2) · Acenocoumarol (1) · Craniotomy (1) · Dabigatran (1) · Dexmedetomidine (1) · Fentanyl (1) · Fingolimod Hydrochloride (1) · Hemostasis (1) · Hydromorphone (1) · Immunization, Passive (1) · Immunoglobulins, Intravenous (1) · Ketamine (1) · Lorazepam (1) · Magnetic Resonance Imaging (1)
Guangzhou University of Traditional Chinese Medicine (2) · Huazhong University of Science and Technology (2) · Shanghai Changzheng Hospital (2) · Beijing Tiantan Hospital (1) · Bispebjerg Hospital (1) · Chinese PLA General Hospital (1) · Henry M. Jackson Foundation for the Advancement of Military Medicine (1) · Leiden University Medical Center (1) · Qianfoshan Hospital (1) · RenJi Hospital (1) · The First People's Hospital of Jingzhou (1) · Tongji Hospital (1) · University Hospital, Grenoble (1) · University of Edinburgh (1) · University of Rijeka (1)
China (11) · United States (3) · Denmark (1) · France (1) · Netherlands (1) · United Kingdom (1)
Lijun Hou, MD,PhD (2) · Bradley Dengler, MD (1) · Ellis van Etten, MD, PhD (1) · Jianjun Wang, Ph.D. (1) · Qian Zhang, MD (1) · Rustam Al-Shahi Salman, MA PhD FRCP (1) · Stacey Q Wolfe, MD (1) · Tao Xu, MD,PhD (1) · Vlatka Sotosek Tokmadzic, PhD (1) · Wei Wang, Doctor (1) · Xiaolei Chen, MD (1) · Xueyan Cui, Ph.D. (1) · Zhang Le, PhD (1) · Zhouping Tang, doctor (1) · Zhu Suiqiang, doctor (1)
PMID 12296635, PMID 14238966, PMID 15145991, PMID 15243684, PMID 16464365, PMID 16543624, PMID 16703877, PMID 17210899, PMID 17213720, PMID 17463317, PMID 17522793, PMID 17919462, PMID 18474003, PMID 18843711, PMID 19059471, PMID 19372001, PMID 19715392, PMID 19726011, PMID 20068459, PMID 21505900, PMID 21782444, PMID 22274965, PMID 22843271, PMID 23095732, PMID 23234472, PMID 2350622, PMID 24481284, PMID 25208667, PMID 25208677, PMID 25541084, PMID 25888429, PMID 26755455, PMID 27338955, PMID 27654000, PMID 28548592, PMID 28659171, PMID 28919116, PMID 29088962, PMID 30224926, PMID 30236140, PMID 31037639, PMID 31340932, PMID 31367614, PMID 34022170, PMID 34487721, PMID 34487722, PMID 35508390, PMID 36446240, PMID 36481437, PMID 36700520
2016 (1), UL1TR001420 (1)