272 completed. 272 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 272 | Completed 272 |
Follow Insulin Resistance: new trials by email Literature Review of Insulin Resistance trials Research Report on Insulin Resistance
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of NOSHINtrial in Diabetic Patients anti-diabetic herbal drug - Diabetes Mellitus, Type 2, Insulin Resistance | Phase 4 | Completed | Kerman Medical University | 70 | 2025-09-26 | 2026-08-10 |
| Metformin Effects on Metabolic, Vitamin B12, Iron, Erythropoietin, and Hematological Parameters in Women With PCOS Metformin, Matching Placebo - Polycystic Ovary Syndrome (PCOS) Women | Phase 4 | Completed | Jerash Private University | 400 | 2025-08-01 | 2026-08-31 |
| Association Between Diastolic Dysfunction and Erectile Dysfunction and the Effect of Tadalafil and SGLT2 Inhibitors on Them in Men With Metabolic Syndrome Tadalafil 5 mg, SGLT-2 inhibitor, Tadalafil plus SGLT2 inhibitors - Erectile Dysfunction, Left Ventricular Diastolic Dysfunction | Phase 4 | Completed | Kafrelsheikh University | 60 | 2025-05-05 | 2026-05-04 |
| Topical Insulin for Ocular Surface Interface in Dry Eye Disease Artificial tear, insulin human - Dry Eye, Insulin Sensitivity | Phase 4 | Completed | Khyber Teaching Hospital | 128 | 2025-04-14 | 2026-08-14 |
| Evaluating the Efficacy and Safety of Empagliflozin Addition to Insulin and Oral Antidiabetic Medication (OAD) Regimen in Poorly Controlled Type 2 Diabetes and Obese Patient Empagliflozin 10 MG, Insulin+Metformin+DPP4 inhibitor (DPP4I) - Glucose Metabolism Disorders, Diabetes Mellitus, Type 2 | Phase 4 | Completed | SINA Health Education and Welfare Trust | 150 | 2023-12-01 | 2024-04-08 |
| 5 Versus 10 Units of Insulin in Hyperkalemia Management Insulin regular, Dextrose 50, salbutamol - Hyperkalemia, Potassium Imbalance | Phase 4 | Completed | Oman Medical Speciality Board | 384 | 2023-10-01 | 2025-12-22 |
| INHALE-3: Afrezza® Combined With Insulin Degludec Versus Usual Care in Adults With Type 1 Diabetes Afrezza, insulin degludec, Rapid-acting Insulin Analog - Diabetes Mellitus, Type 1 | Phase 4 | Completed | Mannkind Corporation | 141 | 2023-07-07 | 2024-08-09 |
| Relationship Between Metformin Treatment, Anemia, and Erythropoietin Levels in Women With Polycystic Ovary Syndrome in Jordan Metformin - Polycystic Ovary Syndrome (PCOS) Women, Insulin Resistance Syndrome | Phase 4 | Completed | Jerash Private University | 25 | 2023-06-01 | 2026-08-12 |
| Human Versus Analogue Insulin for Youth With Type 1 Diabetes in Low-Resource Settings Insulin Glargine, NPH or premixed 70/30 (human insulin) - Diabetes Mellitus, Type 1, Type 1 Diabetes | Phase 4 | Completed | Jing Luo | 400 | 2023-03-15 | 2025-09-10 |
| Clinical Trial To Determine The Effectiveness And Safety Of Topical Insulin In Dry Eye Insulin, Cyclosporins, Artificial tears - Dry Eye, Insulin | Phase 4 | Completed | Barbara Burgos Blasco | 116 | 2022-10-19 | 2026-03-05 |
| Topiramate vs Metformin on Cardio-Metabolic Profile in Schizophrenia on Atypical Antipsychotics Metformin, Topiramate - Metabolic Syndrome, Schizophrenia | Phase 4 | Completed | All India Institute of Medical Sciences, Bhubaneswar | 60 | 2022-09-20 | 2023-08-22 |
| Afrezza With Basal Combination (ABC): Afrezza® Combined With AID Pump or Insulin Degludec in Adults With Type 1 Diabetes Afrezza (insulin human) Inhalation Powder, insulin degludec, Continuous Subcutaneous Insulin Infusion (CSII) pump with Automatic Insulin Delivery (AID) - Type 1 Diabetes | Phase 4 | Completed | Mannkind Corporation | 33 | 2022-03-31 | 2025-04-08 |
| Effect of Polysaccharide-based Complex Administration on the Gut Microbiome and Cardio-Metabolic Profile in Children With Obesity and Metabolic Syndrome. Polysaccharide-based complex - Childhood Obesity | Phase 4 | Completed | University of Milan | 36 | 2022-02-01 | 2026-01-06 |
| Afrezza® Dosing Optimization Study Afrezza Dose 1, Afrezza Dose 2 - Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2 | Phase 4 | Completed | Mannkind Corporation | 20 | 2021-04-09 | 2023-09-18 |
| Insulin for Hyperglycemia in Stroke Trial Analog Insulin, Human insulin - Hyperglycemia, Stroke, Acute | Phase 4 | Completed | National Institute of Neurosciences and Hospital, Dhaka | 452 | 2021-04-05 | 2021-12-06 |
| Effect of Alpha Lipoic Acid on Non-alcoholic Fatty Liver Diseases Placebo, Alphalipoic acid - Non-Alcoholic Fatty Liver Disease | Phase 4 | Completed | All India Institute of Medical Sciences, Bhubaneswar | 120 | 2021-02-23 | 2025-08-14 |
| Research on Human Insulin rDNA Safety and Efficacy in Patients With Type 2 Diabetes Mellitus Insulin - Adverse Drug Event, Effect of Drug | Phase 4 | Completed | Getz Pharma | 238 | 2021-01-01 | 2023-02-06 |
| Aldosterone, the Mineralocorticoid Receptor, and Cardiovascular Disease in Obesity Eplerenone, Chlorthalidone with potassium chloride - Metabolic Syndrome, Hypertension | Phase 4 | Completed | Brigham and Women's Hospital | 79 | 2020-12-01 | 2026-09-15 |
| SGLT2 Inhibitors in Patients With PCOS SGLT2 inhibitors, Metformin - Polycystic Ovary Syndrome | Phase 4 | Completed | Shanghai 10th People's Hospital | 68 | 2020-05-01 | 2022-09-10 |
| Insulin Dextrose Infusion vs Nebulized Salbutamol vs Combination of Salbutamol and Insulin Dextrose in Acute Hyperkalemia Salbutamol, Insulin Aspart - Hyperkalemia | Phase 4 | Completed | Nantes University Hospital | 419 | 2019-12-20 | 2026-05-14 |
Showing 20 of 272. Sign in to see all of them.
Metabolic Syndrome (86) · Diabetes Mellitus, Type 2 (60) · Diabetes Mellitus (58) · Obesity (31) · Hypertension (26) · Schizophrenia (18) · Diabetes Mellitus, Type 1 (13) · Hyperglycemia (11) · Glucose Intolerance (10) · Hypogonadism (10) · Inflammation (10) · Prediabetic State (10) · Cardiovascular Diseases (9) · Polycystic Ovary Syndrome (9)
Nutritional and Metabolic Diseases (272) · Hyperinsulinism (271) · Glucose Metabolism Disorders (269) · Metabolic Diseases (269) · Endocrine System Diseases (126) · Pathological Conditions, Signs and Symptoms (64) · Diabetes Mellitus (52) · Signs and Symptoms (48) · Cardiovascular Diseases (43) · Body Weight (39) · Nutrition Disorders (39) · Overnutrition (38) · Vascular Diseases (38) · Overweight (33)
Metformin (35) · Insulin (26) · Insulin Glargine (22) · Pioglitazone (17) · Insulin Aspart (11) · Insulin Lispro (9) · Aripiprazole (8) · Liraglutide (8) · Rosiglitazone (8) · Hydrochlorothiazide (7) · Ezetimibe, Simvastatin Drug Combination (6) · Insulin Detemir (6) · Testosterone (6) · Fenofibrate (5) · Losartan (5)
Gachon University Gil Medical Center (11) · Novartis (6) · AstraZeneca (5) · Eli Lilly and Company (4) · Tanabe Pharma Corporation (4) · Tottori University Hospital (4) · German Diabetes Center (3) · Gulhane School of Medicine (3) · Mannkind Corporation (3) · Massachusetts General Hospital (3) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (3) · North Suffolk Mental Health Association (3) · Stanford University (3) · University Health Network, Toronto (3) · University of Colorado, Denver (3)
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Kazuoki Kondo, MD (4) · David C Henderson, MD (3) · Kevin Kaiserman, MD (3) · Frank LJ Visseren, MD PhD (2) · Gary F. Lewis, MD (2) · Hildo J Lamb, MD PhD (2) · Ingrid M Jazet, MD PhD (2) · Jonathan M. Meyer, MD (2) · Jothydev Kesavadev, MD (2) · Kazuhide Ogino, MD (2) · Mark E Molitch, M.D. (2) · Michael Roden, Prof., MD (2)
PMID 33293204, PMID 36262060, PMID 39641307, PMID 39963952, PMID 15482620, PMID 16842478, PMID 16988754, PMID 17130190, PMID 17229660, PMID 17305652, PMID 17850473, PMID 18394022, PMID 18413332, PMID 18544618, PMID 18670365, PMID 18761646, PMID 18824462, PMID 19053049, PMID 19104769, PMID 19120715, PMID 19125756, PMID 19263591, PMID 19394149, PMID 19546056, PMID 19689921, PMID 19698065, PMID 19732305, PMID 19814947, PMID 19933411, PMID 20022616, PMID 20026785, PMID 20059570, PMID 20101593, PMID 20199136, PMID 20298928, PMID 20414637, PMID 20457512, PMID 20679179, PMID 20739421, PMID 20827028, PMID 20888102, PMID 20937657, PMID 21051774, PMID 21103669, PMID 21105792, PMID 21209881, PMID 21340022, PMID 21454236, PMID 21554991, PMID 21676394
2005 (3), 2016 (3), 2008 (2), 2014 (2), 2015 (1), K01MH095920 (1), K12HD057022 (1), K23AT002862 (1), K23DK068223 (1), K23DK079789 (1), K23HD092893 (1), K23HL086558 (1), K23MH074540 (1), M01RR000827 (1), P30DK063491 (1)