13 completed, 4 unknown, 3 terminated, 1 active not recruiting. 22 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 22 | Completed 13, Unknown 4, Terminated 3, Active not recruiting 1, Withdrawn 1 |
Follow Impaired Glucose Tolerance: new trials by email Literature Review of Impaired Glucose Tolerance trials Research Report on Impaired Glucose Tolerance
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Renin-Angiotensin-Aldosterone System in Adiposity, Blood Pressure and Glucose in African Americans Sacubitril-Valsartan Tab 97-103 MG, Valsartan 160mg, Placebo Oral Tablet - PreDiabetes, Impaired Glucose Tolerance | Phase 4 | Active not recruiting | Ohio State University | 90 | 2020-02-25 | 2025-08-11 |
| Research of Intensive Metabolic Intervention Before Pregnancy in PCOS Acarbose 100 MG, Exenatide, Orlistat - PCOS, Impaired Glucose Tolerance | Phase 4 | Unknown | RenJi Hospital | 160 | 2018-01-01 | 2017-12-26 |
| Effect of Dapagliflozin on Insulin Secretion and Insulin Sensitivity in Patients With Prediabetes Dapagliflozin, Placebo - Prediabetes, Impaired Fasting Glucose | Phase 4 | Completed | University of Guadalajara | 24 | 2016-10-01 | 2020-10-28 |
| Effect of Linagliptin + Metformin on Patients Who do Not Achieve Normoglucemia With Metformine Linagliptin / Metformin Oral Tablet, Metformin - Prediabetic State, Impaired Glucose Tolerance | Phase 4 | Completed | Universidad de Guanajuato | 31 | 2016-09-01 | 2019-09-13 |
| Effect of Berberine Versus Metformin on Glycemic Control, Insulin Sensitivity and Insulin Secretion in Prediabetes Berberine, Metformin - Prediabetes, Impaired Fasting Glucose | Phase 4 | Unknown | University of Guadalajara | 28 | 2016-03-01 | 2023-05-23 |
| Effect of Saxagliptin Treatment on Myocardial Fat Content, and Monocyte Inflammation Saxagliptin, Placebo - Impaired Glucose Tolerance | Phase 4 | Terminated | Baylor College of Medicine | 8 | 2012-02-01 | 2020-01-13 |
| Renin-Angiotensin and Fibrinolysis in Humans: Effect of Long-Term PDE5 Inhibition on Glucose Homeostasis Sildenafil, Placebo, Hyperglycemic clamp - Impaired Glucose Tolerance | Phase 4 | Terminated | Vanderbilt University | 78 | 2011-08-01 | 2017-04-17 |
| Effects of Physical Activity on the Brain in Impaired Glucose Tolerance (IGT) Exercise - Impaired Glucose Tolerance | Phase 4 | Completed | Charite University, Berlin, Germany | 46 | 2010-08-01 | 2016-03-16 |
| Impact of Acarbose on Abnormal Glucose Regulation in Patients With Coronary Artery Disease (AAA Trial) acarbose - Diabetes Mellitus, Impaired Glucose Tolerance | Phase 4 | Unknown | Aichi Gakuin University | 150 | 2009-04-01 | 2012-07-18 |
| Acarbose Cardiovascular Evaluation Trial Acarbose, Matching Placebo - Coronary Heart Disease, Acute Coronary Syndrome | Phase 4 | Completed | University of Oxford | 6526 | 2009-02-17 | 2017-07-25 |
| The Effects of Exenatide on Post-Meal Sugar Peaks and Vascular Health in Obese/Pre-Diabetic Young Adults Exenatide - Obesity, Insulin Resistance | Phase 4 | Withdrawn | Yale University | 2008-08-01 | 2012-12-11 | |
| Beta-cell Function in Glucose Abnormalities and Acute Myocardial Infarction Sitagliptin - Myocardial Infarction, Unstable Angina Pectoris | Phase 4 | Completed | Karolinska Institutet | 85 | 2008-05-01 | 2021-02-12 |
| The Vascular Effects of Exenatide Versus Metformin in Patients With Pre-Diabetes Exenatide, Metformin - Impaired Glucose Tolerance | Phase 4 | Completed | St. Paul Heart Clinic | 50 | 2007-10-01 | 2013-11-08 |
| Effect of Pioglitazone and Exenatide on Body Weight and Beta Cell Function Pioglitazone, Exenatide, Pioglitazone and Exenatide - Type 2 Diabetes, Healthy | Phase 4 | Completed | The University of Texas Health Science Center at San Antonio | 43 | 2007-06-01 | 2018-01-18 |
| The Effect of Exenatide on Weight and Hunger in Obese, Healthy Women exenatide, Placebo - Obesity, Impaired Glucose Tolerance | Phase 4 | Completed | Beth Israel Deaconess Medical Center | 41 | 2007-04-01 | 2017-09-11 |
| Study of Post-meal Blood Sugar Peaks in Association With Vascular Disease in Childhood Obesity Acarbose - Pediatric Obesity, Insulin Resistance | Phase 4 | Terminated | Yale University | 23 | 2006-09-01 | 2013-05-01 |
| Effects of Exenatide on Postprandial Hyperlipidemia and Inflammation Exenatide, Normal Saline - Type 2 Diabetes Mellitus, Impaired Glucose Tolerance | Phase 4 | Completed | Carl T. Hayden VA Medical Center | 39 | 2006-08-01 | 2009-09-10 |
| Telmisartan and Losartan in Hypertensive IGT Telmisartan 80 mg, Losartan 50 mg - Hypertension, Impaired Glucose Tolerance | Phase 4 | Completed | Medical University of Graz | 24 | 2005-01-01 | 2006-12-05 |
| Rosiglitazone Therapy In The Prevention Of Coronary Artery Disease In Patients With Impaired Glucose Tolerance Rosiglitazone, Placebo - Impaired Glucose Tolerance | Phase 4 | Unknown | Denver Research Institute | 60 | 2004-03-01 | 2008-08-12 |
| Physical Exercise Versus Rosiglitazone in CAD and Prediabetes rosiglitazone, physical exercise, control - Impaired Glucose Tolerance | Phase 4 | Completed | University of Leipzig | 45 | 2004-01-01 | 2010-02-02 |
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Glucose Intolerance (22) · Diabetes Mellitus, Type 2 (5) · Insulin Resistance (5) · Obesity (4) · Prediabetic State (4) · Cardiovascular Diseases (2) · Diabetes Mellitus (2) · Hyperglycemia (2) · Hypertension (2) · Pediatric Obesity (2) · Acute Coronary Syndrome (1) · Angina, Unstable (1) · Cognitive Dysfunction (1) · Coronary Artery Disease (1) · Coronary Disease (1)
Glucose Metabolism Disorders (22) · Metabolic Diseases (22) · Nutritional and Metabolic Diseases (22) · Hyperglycemia (20) · Endocrine System Diseases (10) · Diabetes Mellitus (8) · Pathological Conditions, Signs and Symptoms (6) · Signs and Symptoms (6) · Body Weight (5) · Cardiovascular Diseases (5) · Hyperinsulinism (5) · Nutrition Disorders (5) · Overnutrition (5) · Overweight (5) · Vascular Diseases (5)
Exenatide (6) · Acarbose (4) · Metformin (4) · Exercise (2) · Pioglitazone (2) · Rosiglitazone (2) · Valsartan (2) · Berberine (1) · Combined Modality Therapy (1) · Glucose Clamp Technique (1) · Growth Hormone (1) · Linagliptin (1) · Losartan (1) · Orlistat (1) · Saline Solution (1)
University of Guadalajara (2) · Yale University (2) · Aichi Gakuin University (1) · Baylor College of Medicine (1) · Beth Israel Deaconess Medical Center (1) · Carl T. Hayden VA Medical Center (1) · Charite University, Berlin, Germany (1) · Denver Research Institute (1) · Karolinska Institutet (1) · Medical University of Graz (1) · Novartis (1) · Ohio State University (1) · RenJi Hospital (1) · St. Paul Heart Clinic (1) · Stanford University (1)
United States (10) · Mexico (3) · China (2) · Austria (1) · Germany (1) · Hong Kong (1) · Japan (1) · Sweden (1)
Tania S Burgert, MD (2) · Aaron S. Kelly, Ph.D. (1) · Andrew R Hoffman, MD (1) · Devjit Tripathy, MD (1) · Eleftheria Maratos-Flier, MD (1) · Hamdee Y Attallah, MD (1) · Joshua J Joseph, MD (1) · Mandeep Bajaj, MD (1) · Nancy J Brown, MD (1) · Peter D Reaven, MD (1)
PMID 20200309, PMID 20557887, PMID 22040840, PMID 22456695, PMID 22681705, PMID 25173047, PMID 27624579, PMID 28917545, PMID 32641379, PMID 33035598, PMID 33210751, PMID 33888772
K23DK074439 (1), K23DK117041 (1)