35 completed, 14 unknown, 13 terminated, 3 not yet recruiting. 68 Phase 2, 18 Phase 3, 8 Phase 1.
Follow Iatrogenic Disease: new trials by email Literature Review of Iatrogenic Disease trials Research Report on Iatrogenic Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Precision Modulation of Gut Microbiome Enteropathogen Colonization in Critical Illness Synbiotic, Standard of Care (SOC) - Critical Illness | Phase 1 / Phase 2 | Not yet recruiting | University of Calgary | 64 | 2027-01-01 | 2026-09-10 |
| Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated Pneumonia colistimethate sodium, 0.9% Saline - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Not yet recruiting | University Hospital Fattouma Bourguiba | 400 | 2027-01-01 | 2026-10-08 |
| " Study of the Benefit of Nebulized Amikacin in the Treatment of Gram-negative Bacillus Pneumonia Acquired During Mechanical Ventilation in Patients Receiving Extracorporeal Membrane Veno-arterial Oxygenation " Amikacin, Standard of care - Pneumonia, Bacterial, Extracorporeal Membrane Oxygenation | Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 26 | 2026-08-10 | 2026-08-13 |
| Microbiome-guided Prophylaxis to Reduce Ventilator-Associated Pneumonia in Intensive Care Units: A Pilot Randomized Controlled Trial Microbiome-guided inhaled antibiotic prophylaxis, Placebo - Critical Illness, Mechanical Ventilation | Phase 2 | Not yet recruiting | University of Calgary | 70 | 2026-05-01 | 2026-03-11 |
| Phase 1/2a to Assess the Safety and Tolerability of TP-122A for the Treatment of Ventilator-Associated Pneumonia TP-122A - Pneumonia, Ventilator-Associated | Phase 1 / Phase 2 | Unknown | Technophage, SA | 15 | 2024-09-01 | 2024-04-17 |
| "Baricitinib for Treating Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype. Baricitinib 4 MG - Hospital-acquired Pneumonia | Phase 2 / Phase 3 | Unknown | Nantes University Hospital | 450 | 2023-07-01 | 2023-06-22 |
| Oro-nasal Decontamination to Prevent Ventilator-associated Pneumonia Povidone-Iodine, Saline spray - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Completed | Menoufia University | 78 | 2023-06-24 | 2023-11-27 |
| PK of BV100 in Patients VABP Suspected or Confirmed to Be Due to CRAB BV100 plus Polymyxin B, BAT - Ventilator Associated Pneumonia | Phase 2 | Completed | BioVersys AG | 39 | 2023-04-20 | 2025-01-14 |
| Use of Presepsin as a Marker for Immunotherapy Administration in Pneumonia Anakinra Prefilled Syringe, Placebo - Community-acquired Pneumonia, Hospital-acquired Pneumonia | Phase 2 | Completed | Hellenic Institute for the Study of Sepsis | 60 | 2023-03-06 | 2024-07-31 |
| Red Light Photobiomodulation and Topical Disinfectants Methylene Blue Only, Chlorhexidine Gluconate Only, Methylene Blue + Chlorhexidine Gluconate - Healthcare Associated Infection, Nosocomial Infection | Phase 1 / Phase 2 | Completed | Ondine Biomedical Inc. | 28 | 2023-01-10 | 2023-04-04 |
| Safety of Nebulized Combination Therapy BromAc® in COVID-19 Respiratory Disease Bromelains, Acetylcysteine - COVID-19 Pneumonia, COVID-19 | Phase 1 / Phase 2 | Unknown | Mucpharm Pty Ltd | 30 | 2022-05-01 | 2022-02-28 |
| Intravenous Metoprolol in Septic Shock Intravenous metoprolol tartrate, Standard Care (in control arm) - Septic Shock, Ventilator Acquired Pneumonia | Phase 2 | Completed | Alexandria University | 100 | 2022-04-01 | 2025-01-29 |
| Nasal Photodisinfection in All Patients Presenting for Surgery for a Wide Range of Surgical Procedures methylene blue 0.01%/chlorhexidine gluconate 0.25% + light activation - Surgical Site Infections, Nosocomial Infection | Phase 2 | Completed | Ondine Biomedical Inc. | 322 | 2022-02-04 | 2022-08-22 |
| A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants Cefiderocol, Standard of Care - Gram-negative Bacterial Infections, Bloodstream Infections (BSI) | Phase 2 | Completed | Shionogi | 53 | 2020-08-21 | 2026-02-27 |
| NO Prevention of COVID-19 for Healthcare Providers Inhaled nitric oxide gas - Coronavirus Infections, Healthcare Associated Infection | Phase 2 | Terminated | Massachusetts General Hospital | 24 | 2020-04-07 | 2026-03-20 |
| Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia VC, Sterile Water for Injection - Vitamin C, Pneumonia, Viral | Phase 2 | Terminated | ZhiYong Peng | 56 | 2020-02-14 | 2020-10-12 |
| Umbilical Cord(UC)-Derived Mesenchymal Stem Cells(MSCs) Treatment for the 2019-novel Coronavirus(nCOV) Pneumonia UC-MSCs - Pneumonia, Viral, Pneumonia, Ventilator-Associated | Phase 2 | Unknown | ZhiYong Peng | 16 | 2020-02-06 | 2020-07-01 |
| Inulin for Infections in the Intensive Care Unit Inulin Oral Suspension, Placebo Oral Suspension, Broad-spectrum antibiotics - Antibiotic Resistant Infection, Nosocomial Infection | Phase 2 | Completed | Columbia University | 94 | 2019-10-14 | 2025-06-19 |
| Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia EVAC-PU-ETT, PVC-ETT - Ventilator-acquired Pneumonia | Phase 2 | Completed | Yale University | 1074 | 2019-05-06 | 2024-09-24 |
| Coated Devices to Decrease Infection in the Intensive Care Unit Coated devices, Control - Critically Ill | Phase 1 / Phase 2 | Completed | Hospital do Coracao | 103 | 2019-04-06 | 2020-03-09 |
Showing 20 of 68. Sign in to see all of them.
Pneumonia, Ventilator-Associated (42) · Cross Infection (22) · Pneumonia (20) · Healthcare-Associated Pneumonia (13) · Critical Illness (6) · Sepsis (6) · Surgical Wound Infection (6) · Infections (5) · Pseudomonas Infections (5) · Pneumonia, Bacterial (4) · Bacterial Infections (3) · Respiratory Tract Infections (3) · Bacteremia (2) · COVID-19 (2) · Fever (2)
Disease Attributes (68) · Pathologic Processes (68) · Pathological Conditions, Signs and Symptoms (68) · Infections (63) · Respiratory Tract Diseases (52) · Lung Diseases (50) · Respiratory Tract Infections (48) · Cross Infection (46) · Healthcare-Associated Pneumonia (35) · Pneumonia (30) · Bacterial Infections and Mycoses (15) · Bacterial Infections (12) · Inflammation (10) · Systemic Inflammatory Response Syndrome (9)
Standard of Care (4) · Colistin (3) · Doripenem (3) · Saline Solution (3) · Amikacin (2) · Ascorbic Acid (2) · Ceftazidime (2) · Chlorhexidine (2) · Cilastatin, Imipenem Drug Combination (2) · Injections (2) · Polymyxin B (2) · Povidone-Iodine (2) · Sodium Chloride (2) · Toothbrushing (2) · Vancomycin (2)
Emory University (3) · Hospital Universitari Joan XXIII de Tarragona. (2) · Ondine Biomedical Inc. (2) · University of Calgary (2) · ZhiYong Peng (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Agennix (1) · Aionx, Inc. (1) · Alexandria University (1) · Anbics Management-Services Ag (1) · Angela Bianco (1) · Arpida AG (1) · Arsanis, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Association Pour La Promotion A Tours De La Reanimation Medicale (1)
United States (24) · France (11) · Spain (7) · Canada (6) · China (6) · Hungary (4) · Russia (4) · Belgium (3) · Georgia (3) · Greece (3) · Ukraine (3) · Argentina (2) · Austria (2) · Brazil (2) · Chile (2)
Aaron Milstone, MD MHS (1) · Alexandre Biasi, MD/PhD (1) · Angela Bianco, MD (1) · Antoni Torres, MD PhD (1) · Avery B Nathens, MD PhD MPH (1) · Christian Van Delden, MD (1) · Cindy L Munro, RN,ANP,PHD (1) · Cindy Munro, RN, ANP,PhD (1) · Daniel E Freedberg, MD, MS (1) · Daren Heyland, MD (1) · David Lye, MBBS, FRACP (1) · David Willms, MD (1) · Deborah J Cook, MD (1)
PMID 16980879, PMID 17076839, PMID 17119142, PMID 18461895, PMID 18991508, PMID 19482956, PMID 19765321, PMID 20463812, PMID 21287306, PMID 22488002, PMID 23357775, PMID 23363666, PMID 24981955, PMID 25050644, PMID 25317722, PMID 26472037, PMID 27080532, PMID 27234409, PMID 27260839, PMID 27419080, PMID 27480757, PMID 27965798, PMID 28159015, PMID 28186383, PMID 29041861, PMID 30526610, PMID 32335895, PMID 32526149, PMID 32580252, PMID 32595159, PMID 32641343, PMID 33570583, PMID 36289153, PMID 37068952, PMID 37947276, PMID 38676438, PMID 39230271, PMID 39806400, PMID 40237647, PMID 41319662, PMID 41552367, PMID 42047567, PMID 42497015, PMID 8888088
R01NR007652 (2), 2016 (1), 2019 (1), P50HL073996 (1), R01DE014685 (1), R21DK089369 (1), R33HL138650 (1), R44HD057744 (1)