Insulin, Regular, Human: Clinical Trials

28 trials of Insulin, Regular, Human, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

16 completed, 8 terminated, 1 active not recruiting, 1 recruiting. 10 Phase 2, 9 Phase 3, 7 Phase 1, 4 Not applicable, 2 Early Phase 1.

By phase and status

PhaseTrialsStatus
Phase 210Terminated 5, Completed 4, Withdrawn 1
Phase 39Terminated 6, Recruiting 1, Unknown 1, Withdrawn 1
Phase 17Completed 5, Terminated 2
Not applicable4Completed 3, Active not recruiting 1
Early Phase 12Completed 2
Phase 42Completed 2

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
RCT Glargine vs NPH for Treatment of DM in Pregnancy
Insulin glargine, insulin NPH - Diabetes Mellitus in Pregnancy, Type 2 Diabetes Mellitus (T2DM)
Phase 3RecruitingLoyola University1602024-04-012024-10-01
Food Intake and Intra-Nasal Insulin for African American Adults (FIINAAL)
Insulin, Regular, Human, Placebo - Insulin
Phase 1CompletedPennington Biomedical Research Center402021-06-172023-11-29
A Trial to Assess a Co-formulation of an Insulin Analog and Pramlintide in Subjects With Type 1 Diabetes Mellitus
ADO09 formulation, Placebo, Symlin® - Type 1 Diabetes Mellitus
Phase 1CompletedAdocia242019-01-042019-04-16
A Trial to Investigate Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BioChaperone® Pramlintide Insulin in Patients With Type 1 Diabetes Mellitus
BC Pram Ins, Symlin® and Humulin®, Humalog® - Type 1 Diabetes Mellitus
Phase 1CompletedAdocia242018-04-252019-02-21
A Study to Identify Biomarkers of Hypoglycaemia in Patients With Type 2 Diabetes
Humulin S - Type 2 Diabetes Mellitus With Hypoglycemia
Not applicableCompletedUniversity of Hull502017-03-012018-11-01
Identifying the Brain Substrates of Hypoglycemia Unawareness in Type 1 Diabetes
Insulin, Glucose, Potassium phosphate - Hypoglycemia
Early Phase 1CompletedUniversity of Minnesota272016-11-012021-02-01
Reprometabolic Syndrome Mediates Subfertility in Obesity
Insulin, Intralipid, Dextrose - Obesity, Infertility
Not applicableActive not recruitingUniversity of Colorado, Denver842016-06-012026-03-02
A Study of U-500 Insulin (LY041001) in Participants With Type 2 Diabetes
U-500R - Diabetes Mellitus, Type 2
Phase 1TerminatedEli Lilly and Company112016-01-122023-10-23
Humalog or Humulin for Intensive Insulin Therapy in Intensive Care Unit
Regular-insulin, Lispro-insulin - Hyperglycemia
Phase 4CompletedUniversity of Roma La Sapienza282013-03-012014-06-17
Molecular Regulation of Muscle Glucose Metabolism
U100 Humulin, Exercise - Obesity, Type 2 Diabetes Mellitus
Phase 1TerminatedMayo Clinic482012-04-012017-11-27
Insulin Receptor Substrate 1 (IRS-1) Regulation in Insulin Resistance
Human insulin - Type 2 Diabetes Mellitus
Phase 1CompletedMayo Clinic142012-03-012013-06-05
The Effects of Hypoglycaemia in People With Type 2 Diabetes
Insulin (Humulin S), Euglycaemic Hypoglycaemic Insulin clamp - Type 2 Diabetes Mellitus
Not applicableCompletedUniversity of Hull182011-11-012014-08-01
To Compare the Effect of a Subcutaneous Canakinumab Administration to Placebo in Patients With Impaired Glucose Tolerance or Patients With Type 2 Diabetes With Differing Baseline Diabetes Therapies
Canakinumab 150 mg, Placebo to Canakinumab - Type 2 Diabetes Mellitus, Impaired Glucose Tolerance
Phase 2CompletedNovartis2462010-02-012011-09-05
Effects of Intensive Bolus Intravenous Insulin Delivery on Metabolic Integrity in Type 1 and Type 2 Diabetes
Humulin, Humalog, Novolog - Diabetes Mellitus, Metabolic Integrity
Phase 3UnknownGlobal Infusion and Aspiration Systems, LLC20002009-11-012011-06-22
Efficiency of Two Glucose Sampling Protocols for Maintenance of Euglycemia
Insulin - Brain Neoplasms, Intracranial Aneurysm
Early Phase 1CompletedNorthwestern University1202009-10-012019-12-13
Liquid Meal Study With Insulin Lispro With/Without Recombinant Human Hyaluronidase PH20 (rHuPH20) and Regular Human Insulin With rHuPH20 to Compare Pharmacokinetics, Postprandial Glycemic Response, and Optimal Insulin Dose in Participants With Type 2 Diabetes Mellitus (T2DM)
Humalog, Humulin-R, Recombinant human hyaluronidase PH20 (rHuPH20) - Diabetes Mellitus, Type 2
Phase 2CompletedHalozyme Therapeutics232009-07-012014-08-18
Phase II Pharmacokinetics Study of Humalog and Humulin-R With and Without rHuPH20 in Type 1 Diabetes Mellitus
Humalog, Humulin-R, Recombinant human hyaluronidase PH20 (rHuPH20) - Type 1 Diabetes Mellitus
Phase 2CompletedHalozyme Therapeutics222008-10-012019-02-26
Pharmacokinetic (PK), Pharmacodynamic (PD), and Safety Study of Subcutaneously Administered Humalog® With and Without Recombinant Human Hyaluronidase (rHuPH20)and Humulin-R® With and Without rHuPH20
Humalog, Humulin-R, Recombinant human hyaluronidase PH20 (rHuPH20) - Diabetes Mellitus
Phase 1CompletedHalozyme Therapeutics262007-12-012019-02-26
Feasibility Study of the Effect of Intra-Dermal Insulin Injection on Blood Glucose Levels After Eating
Regular insulin (Humulin), Insulin lispro (Humalog) - Diabetes Mellitus, Type 1
Phase 2CompletedBecton, Dickinson and Company302007-09-012008-08-22
Effects of Pulsed Intravenous (IV) Insulin on Brittle and Uncontrolled Diabetes
Pulsatile Intravenous Insulin Therapy (Humulin, Humulog, Novolog ) - Diabetes Mellitus
Phase 3TerminatedFlorida Atlantic University3002007-03-012016-02-03

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Conditions studied

Hypoglycemia (10)  ·  Diabetes Mellitus (9)  ·  Insulin Resistance (9)  ·  Diabetes Mellitus, Type 2 (7)  ·  Diabetes Complications (6)  ·  Diabetes Mellitus, Type 1 (4)  ·  Diabetic Neuropathies (2)  ·  Hyperglycemia (2)  ·  Obesity (2)  ·  Brain Neoplasms (1)  ·  Diabetes, Gestational (1)  ·  Glucose Intolerance (1)  ·  Hyperinsulinism (1)  ·  Infertility (1)  ·  Inflammation (1)

Sponsors

Florida Atlantic University (7)  ·  Halozyme Therapeutics (3)  ·  Adocia (2)  ·  Mayo Clinic (2)  ·  University of Hull (2)  ·  Becton, Dickinson and Company (1)  ·  Eli Lilly and Company (1)  ·  Global Infusion and Aspiration Systems, LLC (1)  ·  King Saud University (1)  ·  Loyola University (1)  ·  Northwestern University (1)  ·  Novartis (1)  ·  Pennington Biomedical Research Center (1)  ·  University of Colorado, Denver (1)  ·  University of Massachusetts, Worcester (1)

Countries

United States (21)  ·  Germany (4)  ·  Italy (2)  ·  United Kingdom (2)  ·  Australia (1)  ·  Canada (1)  ·  Finland (1)  ·  India (1)  ·  Saudi Arabia (1)

Top investigators

Betty Tuller, PhD (4)  ·  Betty Tuller, Ph.D (2)  ·  Grit Andersen, MD (2)  ·  Betty Tuller, Ph.D. (1)  ·  Christoph Kapitza, MD (1)  ·  Dhanesh Gupta, MD (1)  ·  Federico Bilotta, MD, PhD (1)  ·  Joana Lopes Perdigao, MD (1)  ·  Khalid A Al-Rubeaan, MD (1)  ·  Lawrence J. Mandarino, PhD (1)  ·  Lawrence Mandarino, PhD (1)  ·  Linda A Morrow, M.D. (1)  ·  Lori Roust, MD (1)  ·  Marcus Hompesch, M.D. (1)

Results publications

PMID 33931404, PMID 36203210, PMID 19459762, PMID 21273493, PMID 21355716, PMID 22136324, PMID 25466315, PMID 32949593, PMID 33157081, PMID 33742062, PMID 33838870, PMID 33859620, PMID 33879515, PMID 34248840, PMID 34248841, PMID 34426634, PMID 34645474, PMID 34831332, PMID 34926573, PMID 35415885, PMID 36017315, PMID 36499023, PMID 36643727, PMID 38710978, PMID 41712301

NIH funding

R01DK047936 (1), UL1TR001082 (1)