21 completed, 13 unknown, 7 terminated, 2 active not recruiting. 20 Not applicable, 7 Phase 4, 5 Phase 2, 3 Phase 1, 2 Phase 3.
Follow Hypertension Resistant to Conventional Therapy: new trials by email Literature Review of Hypertension Resistant to Conventional Therapy trials Research Report on Hypertension Resistant to Conventional Therapy
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Expand Management of Blood Pressure With Renal Denervation in Patients Undergoing Staged PCI for Advanced Coronary Artery diseasE Renal denervation - Multivessel Coronary Artery Disease, Hypertension Resistant to Conventional Therapy | Not applicable | Not yet recruiting | Ceric Sàrl | 1000 | 2026-11-01 | 2026-05-22 |
| Antihypertensive Mechanisms of Minocycline in Resistant Hypertension Minocycline Hydrochloride, Placebo - Hypertension, Resistant to Conventional Therapy | Phase 4 | Recruiting | University of Florida | 120 | 2025-01-08 | 2026-10-13 |
| Baroloop Multicenter Trial (Baroloop MCT) baroloop system - Hypertension, Resistant to Conventional Therapy | Not applicable | Terminated | neuroloop GmbH | 3 | 2024-05-22 | 2026-10-20 |
| A Preventive, Multidisciplinary Primary Care Intervention Organized Around a Therapeutic Garden: Acceptability to Patients Suffering From Cardio-neurovascular Pathology and to Those Involved in the Action. Intervention of prevention - Vascular Disease, Cardiovascular | Not applicable | Active not recruiting | Assistance Publique Hopitaux De Marseille | 157 | 2024-04-09 | 2026-11-10 |
| RADIANCE Continued Access Protocol Renal Denervation - Hypertension, Hypertension, Resistant to Conventional Therapy | Not applicable | Active not recruiting | ReCor Medical, Inc. | 300 | 2022-05-04 | 2024-06-17 |
| Use of Automated Office Blood Pressure Monitoring Blood pressure measurement device - Hypertension, Uncontrolled Hypertension | Not applicable | Completed | University of Alabama at Birmingham | 28 | 2021-03-05 | 2022-05-27 |
| UK Registry for Baroreflex Activation Therapy Baroreflex Activation Therapy with Barostim Neo - Baroreflex Failure Syndrome, Hypertension, Resistant to Conventional Therapy | Not applicable | Terminated | Queen Mary University of London | 6 | 2018-11-01 | 2023-06-08 |
| MANP in African Americans With Hypertension Placebo - 1st Cycle, MANP - 1st Cycle, MANP - 2nd Cycle - Hypertension, Resistant to Conventional Therapy | Phase 1 | Withdrawn | Mayo Clinic | 2018-05-01 | 2023-03-09 | |
| Moderato System in Patients With Hypertension BackBeat Moderato System, BackBeat Moderato Sytsem - Hypertension, Resistant to Conventional Therapy, Atrioventricular Block | Not applicable | Terminated | BackBeat Medical Inc | 203 | 2017-08-30 | 2026-06-18 |
| High Prevalence of Secondary Arterial Hypertension (HIPRESH) with Prospective Systematic Screening in a Cohort of Consecutive Hypertensive Patients Referring to Regional Specialized Center Hypertension, Hypertension Resistant to Conventional Therapy | Completed | University Hospital Padova | 1400 | 2017-01-01 | 2024-10-29 | |
| Health Coaching Based Treatment Versus Usual Treatment of Systemic Arterial Hypertension and Comorbidities Health Coaching, Multiprofessional Team - Hypertension, Resistant to Conventional Therapy | Not applicable | Unknown | Universidade Federal de Goias | 150 | 2016-12-01 | 2017-02-08 |
| Moderato System: A Double-Blind Randomized Trial Ver 1.1 PHC ON, PHC OFF - Hypertension Resistant to Conventional Therapy, Bradycardia | Not applicable | Terminated | BackBeat Medical Inc | 70 | 2016-07-12 | 2026-06-18 |
| A Study to Evaluate Safety and Efficacy of the Redy™ Renal Denervation System in the Treatment of Patients With Uncontrolled Hypertension Redy™ Renal Denervation System - Hypertension Resistant to Conventional Therapy | Not applicable | Unknown | Renal Dynamics GmbH | 55 | 2016-04-01 | 2016-05-11 |
| Chemical Renal Ethanol Sympatholysis Under CT Guidance Use for the Control of Therapy-Resistant Hypertension Renal sympathicolysis, Ambulatory Blood Pressure Monitoring, Magnetic Resonance Angiography - Hypertension Resistant to Conventional Therapy, Kidney Failure, Chronic | Phase 2 | Terminated | University Hospital, Grenoble | 2 | 2016-02-01 | 2018-05-09 |
| The Use of Ambulatory Blood Pressure Monitors to Assess Angiotensin Converting Enzyme Inhibitors Equivalent dose enalapril, Equivalent dose lisinopril - Hypertension, Resistant to Conventional Therapy | Phase 1 | Unknown | Memorial Health University Medical Center | 20 | 2015-11-01 | 2017-05-25 |
| Peripheral Chemoreflex/Arterial Baroreflex Interaction in Patients With Electrical Carotid Sinus Stimulation Hypoxia without dopamine, Hypoxia with dopamine, Hyperoxia without dopamine - Hypertension, Resistant to Conventional Therapy | Not applicable | Completed | Hannover Medical School | 11 | 2015-11-01 | 2018-01-09 |
| Sequential Nephron Blockade vs. Dual Blockade Renin-angiotensin System + Bisoprolol in Resistant Arterial Hypertension Spironolactone, Furosemide,, Amiloride - Hypertension Resistant to Conventional Therapy | Phase 4 | Completed | Sao Jose do Rio Preto Medical School | 72 | 2015-09-01 | 2019-04-05 |
| Renal Artery Stenting in Patients With Documented Resistant Hypertension and Atherosclerotic Renal Artery Stenosis (ANDORRA) Renal artery Angioplasty plus stenting., Anti hypertensive, statin and antiplatelet medication. - Hypertension, Hypertension Resistant to Conventional Therapy | Phase 4 | Terminated | Assistance Publique - Hôpitaux de Paris | 4 | 2015-09-01 | 2018-01-26 |
| CPAP Effect on Blood Pressure and Arterial Stiffness in Obstructive Sleep Apnea Patients With Resistant Hypertension Hypertension, Resistant to Conventional Therapy, Obstructive Sleep Apnea | Unknown | University Hospital, Grenoble | 166 | 2015-09-01 | 2016-03-07 | |
| How to Test Success of a Renal Denervation Hypertension, Resistant to Conventional Therapy | Terminated | University of Zurich | 11 | 2015-08-01 | 2019-01-14 |
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Hypertension (13) · Essential Hypertension (5) · Cardiovascular Diseases (4) · Vascular Diseases (4) · Atrioventricular Block (3) · Diabetes Mellitus (3) · Atrial Fibrillation (2) · Bradycardia (2) · Kidney Failure, Chronic (2) · Cardiomyopathies (1) · Hyperaldosteronism (1) · Hypertension, Renal (1) · Hypertension, Renovascular (1) · Ischemic Stroke (1)
Cardiovascular Diseases (18) · Vascular Diseases (13) · Pathologic Processes (8) · Pathological Conditions, Signs and Symptoms (8) · Heart Diseases (6) · Arrhythmias, Cardiac (5) · Endocrine System Diseases (4) · Nervous System Diseases (4) · Cardiac Conduction System Disease (3) · Female Urogenital Diseases (3) · Female Urogenital Diseases and Pregnancy Complications (3) · Glucose Metabolism Disorders (3) · Heart Block (3) · Hypertension (3) · Male Urogenital Diseases (3)
Spironolactone (4) · Angiotensin-Converting Enzyme Inhibitors (3) · Antihypertensive Agents (2) · Bisoprolol (2) · Exercise (2) · Sodium Chloride Symporter Inhibitors (2) · Adrenergic beta-Antagonists (1) · Amiloride (1) · Angiotensin Receptor Antagonists (1) · Calcium Channel Blockers (1) · Dopamine (1) · Doxazosin (1) · Enalaprilat (1) · Furosemide (1) · Hematologic Tests (1)
BackBeat Medical Inc (4) · Assistance Publique - Hôpitaux de Paris (2) · University Hospital, Grenoble (2) · University of Cambridge (2) · AGIR à Dom (1) · Assistance Publique Hopitaux De Marseille (1) · Cardiosonic (1) · Cardiovascular Center Frankfurt (1) · Ceric Sàrl (1) · Charite University, Berlin, Germany (1) · China Academy of Chinese Medical Sciences (1) · Chinese Academy of Medical Sciences, Fuwai Hospital (1) · Hannover Medical School (1) · Ib Abildgaard Jacobsen (1) · Maastricht University Medical Center (1)
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PMID 12479763, PMID 15106785, PMID 1647954, PMID 18391085, PMID 18574054, PMID 20651602, PMID 21423678, PMID 21444835, PMID 21502568, PMID 22215711, PMID 22948302, PMID 22958958, PMID 23836798, PMID 24059787, PMID 24591332, PMID 24691452, PMID 24739800, PMID 25186534, PMID 25452198, PMID 25631070, PMID 26253568, PMID 26414968, PMID 27007793, PMID 27246911, PMID 27576780, PMID 28005705, PMID 28115517, PMID 29018027, PMID 29151036, PMID 29433578, PMID 29655877, PMID 31995406, PMID 33107592, PMID 33399016, PMID 34387126, PMID 34806762, PMID 35686551, PMID 36073648, PMID 40801869, PMID 40859651
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