213 completed, 38 unknown, 16 recruiting, 12 active not recruiting. 309 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 309 | Completed 213, Unknown 38, Recruiting 16, Active not recruiting 12, Terminated 12, Not yet recruiting 7, Withdrawn 7, Enrolling by invitation 3, Suspended 1 |
Follow Hypercholesterolemia: new trials by email Literature Review of Hypercholesterolemia trials Research Report on Hypercholesterolemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Metabolic Effects of an Ophiocordyceps Sinensis- and CoQ10-Based Formulation in Mild-to-Moderate Hypercholesterolemia CORDICOL, Placebo - Hypercholesterolemia, Lipid Metabolism Disorders | Not applicable | Not yet recruiting | noiVita Srls | 140 | 2026-10-19 | 2026-10-08 |
| Berberol P for Mild-to-Moderate Hypercholesterolaemia Berberol® P (manufacturer: PharmExtracta S.p.A.), Berberol® K (manufacturer: PharmExtracta S.p.A.) - Hypercholesterolemia | Not applicable | Not yet recruiting | Liaquat University of Medical & Health Sciences | 255 | 2026-09-07 | 2026-08-27 |
| Electronic Letters to Improve Patient Activation in IHD: The NUDGE-IHD Trial LDL-C information letter, Lp(a) information letter - Ischemic Heart Disease, Coronary Artery Disease | Not applicable | Not yet recruiting | Tor Biering-Sørensen | 123000 | 2026-09-01 | 2026-09-08 |
| Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD Moderate-intensity statin and ezetimibe combination therapy, High-intensity statin monotherapy - Renal Insufficiency, Atherosclerosis | Not applicable | Recruiting | Yonsei University | 1952 | 2026-05-28 | 2026-06-16 |
| Advancing Care Coordination Between Cancer and Primary Care Teams for Complex Cancer Survivors PC2: Primary Care Connect - Cancer, Breast Cancer Early Stage Breast Cancer (Stage 1-3) | Not applicable | Enrolling by invitation | Rutgers, The State University of New Jersey | 266 | 2026-04-24 | 2026-07-10 |
| Assessing the Effects of Corn and Avocado Oils on the Cardiometabolic Risk Factor Profile corn oil, Avocado Oil - Hypercholesterolemia | Not applicable | Recruiting | Midwest Center for Metabolic and Cardiovascular Research | 54 | 2026-04-10 | 2026-04-17 |
| Virtual Lifestyle Intervention for Weight Management and Cardiovascular Heal Multicomponent Virtual Lifestyle Intervention - Cardiovascular Risk Factor | Not applicable | Enrolling by invitation | Truemedicine Inc | 200 | 2026-04-10 | 2026-05-07 |
| WB-EMS Effects on Cardiometabolic Risk Factors WB-EMS, Control - Hypertension, Metabolic Syndrome | Not applicable | Active not recruiting | University of Erlangen-Nürnberg Medical School | 28 | 2026-02-15 | 2026-05-14 |
| Investigating The Potential Of A Hay-Aged Cheese To Reduce Cholesterol As Mediated By Changes In The Gut Microbiome Hay-aged cheese, Cheddar control - Cholesterol, Elevated | Not applicable | Active not recruiting | Anisha Wijeyesekera | 40 | 2026-01-26 | 2026-10-21 |
| Effects of LP-LDL® on Lipid Metabolism, Glycemic Control, Inflammatory Markers, and Cognitive Function in Individuals With Prediabetes and Diabetes Mellitus Lactobacillus plantarum ECGC 13110402, Placebo - Diabete Type 1, Diabete Type 2 | Not applicable | Not yet recruiting | Aalborg University | 210 | 2026-01-25 | 2026-01-29 |
| FELLAShip to Better Health FELLAship - High Blood Glucose, High Cholesterol | Not applicable | Recruiting | University of Alabama at Birmingham | 90 | 2026-01-01 | 2026-01-22 |
| Activate Tennessee: A CHW-Supported Program for Patient Activation Intervention, Control Group - Diabetes, Hypertension | Not applicable | Not yet recruiting | Meharry Medical College | 300 | 2025-12-20 | 2025-12-12 |
| Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food Bottarga, Comparator - Prediabetes, Diabetes | Not applicable | Recruiting | Cambridge Health Alliance | 20 | 2025-10-17 | 2026-07-16 |
| Improving Lipid Optimization Quality and Treatment Options in ASCVD Referral to Pharmacist-Driven Medication Management Program, Best-Practice Alert - Hypercholesterolemia, ASCVD | Not applicable | Enrolling by invitation | Brigham and Women's Hospital | 300 | 2025-10-14 | 2026-05-18 |
| Effect of Two Food Supplements on Lipid Profile in Patients With Mild Hypercholesterolemia Cynacol, Metacol - Hypercholesterolemia | Not applicable | Recruiting | Fondazione IRCCS Policlinico San Matteo di Pavia | 40 | 2025-09-30 | 2025-12-19 |
| Healthy Living Anson Study Nutrition Education and Food Delivery, Physical Activity Comparator - Obesity (Disorder), Diabetes Type 2 | Not applicable | Completed | University of North Carolina, Chapel Hill | 44 | 2025-09-24 | 2026-09-28 |
| Study on the Effect of the Intake of a Calcium-bicarbonate Water on Cholesterol Levels Water - Hypercholesterolemia | Not applicable | Completed | Società Generale delle Acque Minerali S.p.A. | 160 | 2025-09-17 | 2026-05-11 |
| Alleviation of Hypercholesterolemia Through Newly Developed Cookies Supplementedwithpumpkin (Cucurbita Pepo L.) Seeds and Walnuts (Juglans Regia L.) Among Arthrosclerosispatients. Pumpkin Seed and Walnut Cookies, Standard Care (Control) - Hypercholesterolemia, Arthrosclerosis | Not applicable | Completed | Kamran Hanif | 25 | 2025-09-15 | 2026-07-30 |
| Dachundou No Sugar Added Soymilk for Lipid Modulation Dachundou No Sugar Added Soymilk - Dyslipidemias, Hypercholesterolemia | Not applicable | Completed | National Taiwan Sport University | 25 | 2025-09-15 | 2026-04-13 |
| An Efficacy and Safety Study of Akkermansia Muciniphila AKM Lab-01 in Hypercholesterolaemia Probiotic, Placebo - Hypercholesterolaemia | Not applicable | Active not recruiting | Moon (Guangzhou) Biotechnology Co., Ltd. | 60 | 2025-06-25 | 2026-10-09 |
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Hypertension (73) · Diabetes Mellitus (56) · Obesity (49) · Cardiovascular Diseases (45) · Hyperlipidemias (34) · Overweight (24) · Diabetes Mellitus, Type 2 (20) · Dyslipidemias (19) · Motor Activity (17) · Metabolic Syndrome (15) · Atherosclerosis (11) · Hyperglycemia (11) · Hypertriglyceridemia (11) · Inflammation (11)
Nutritional and Metabolic Diseases (309) · Metabolic Diseases (306) · Lipid Metabolism Disorders (305) · Dyslipidemias (290) · Hyperlipidemias (275) · Vascular Diseases (91) · Glucose Metabolism Disorders (89) · Cardiovascular Diseases (83) · Pathological Conditions, Signs and Symptoms (82) · Endocrine System Diseases (74) · Signs and Symptoms (64) · Body Weight (59) · Nutrition Disorders (57) · Overnutrition (56) · Behavior (43)
Phytosterols (11) · Simvastatin (7) · plant stanol ester (7) · Diet (6) · Diet Therapy (6) · Ezetimibe (6) · Exercise (5) · Atorvastatin (4) · Methods (4) · Rosuvastatin Calcium (4) · Blood Specimen Collection (3) · Dietary Supplements (3) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (3) · coenzyme Q10 (3) · Aspirin (2)
University of Bologna (10) · Raisio Group (9) · University of Manitoba (7) · Maastricht University Medical Center (5) · Washington University School of Medicine (5) · Duke University (3) · Lescuyer Laboratory (3) · Northwestern University (3) · The Cleveland Clinic (3) · Unilever R&D (3) · Unity Health Toronto (3) · University of Jena (3) · University of Primorska (3) · Valbiotis (3) · AB Biotics, SA (2)
United States (100) · Canada (25) · Italy (23) · France (14) · Germany (14) · Spain (13) · Netherlands (8) · Australia (7) · United Kingdom (7) · China (6) · Finland (6) · Taiwan (5) · Brazil (4) · Denmark (4) · India (4)
Claudio Borghi, MD (4) · Peter Jones, PhD (4) · Benoit Lamarche, PhD (3) · Gerhard Jahreis, Prof. Dr. (3) · Jiri Frohlich, MD (3) · Carla Taylor, PhD (2) · David J Jenkins, MD (2) · Deepak Voora, MD (2) · Hayden B Bosworth, PhD (2) · Raquel Mateos, Dr (2) · Wieneke Koppenol, MSc (2) · Abhijit Venu (1) · Ad Masclee, MD (1) · Adele Costabile, PhD (1) · Aileen P Wright, MD, MS (1)
PMID 33380172, PMID 12485966, PMID 12620529, PMID 16522904, PMID 16818923, PMID 16843192, PMID 17384344, PMID 18078870, PMID 18439712, PMID 18559131, PMID 18754003, PMID 18957532, PMID 19200384, PMID 19369238, PMID 19463517, PMID 19709787, PMID 19889819, PMID 20495438, PMID 20529243, PMID 20573639, PMID 20599337, PMID 20624475, PMID 20805984, PMID 20808333, PMID 20837464, PMID 20860820, PMID 21122701, PMID 21181050, PMID 21286407, PMID 21481713, PMID 21600524, PMID 21768541, PMID 21775117, PMID 21862744, PMID 21910898, PMID 21944261, PMID 21952693, PMID 22024489, PMID 22085317, PMID 22170364, PMID 22360862, PMID 22815653, PMID 22963235, PMID 23113909, PMID 23143672, PMID 23146744, PMID 23187956, PMID 23266743, PMID 23442351, PMID 23449607
OT2HL158287 (3), P01HS021141 (2), 2023 (1), 7RC4AG039072-02 (1), I01HX003477 (1), K24DK068380 (1), M01RR000042 (1), M01RR000400 (1), P01AG018784 (1), P30AG022849 (1), R01AG015982 (1), R01DK061167 (1), R01HL050420 (1), R01HL058008 (1), R01HL068057 (1)