26 completed, 19 unknown, 12 not yet recruiting, 12 recruiting. 88 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 88 | Completed 26, Unknown 19, Not yet recruiting 12, Recruiting 12, Terminated 10, Active not recruiting 7, Suspended 1, Withdrawn 1 |
Follow Hydrocephalus: new trials by email Literature Review of Hydrocephalus trials Research Report on Hydrocephalus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Addressing Health Disparities in Normal Pressure Hydrocephalus (NPH) in Maryland patients will receive NPH education, primary care physicians (PCPs) will receive professional NPH education, A community health worker will assist PCP - Normal Pressure Hydrocephalus, Hakim Syndrome | Not applicable | Not yet recruiting | Johns Hopkins Bloomberg School of Public Health | 660 | 2027-08-01 | 2026-05-07 |
| A Prospective Study Comparing CSF Shunt Flow Between "Virtual Off" and "Flow Permissive" Shunt Valve Settings Using a Wireless, Noninvasive Shunt Flow Sensor Rhaeos Shunt Monitoring System (RSMS), ShuntCheck III - Hydrocephalus | Not applicable | Not yet recruiting | Rhaeos, Inc. | 85 | 2026-09-08 | 2026-09-11 |
| Ultrasound and Photoacoustic Imaging of Hydrocephalus in Pediatric Patients PAUS imaging - Hydrocephalus in Infants, Hydrocephalus in Children | Not applicable | Not yet recruiting | Michael McDowell | 250 | 2026-09-01 | 2026-08-25 |
| Role of Endoscopic Third Ventriculostomy Imanagement of Hydrocephalus in Pediatric Age Group; Clinical and Surgical Outcome Fenestration of the floor of the third ventricle, Endoscopic third ventriculostomy of the brain third ventricle, Endoscopic third ventriculostomy - Hydrocephalus | Not applicable | Not yet recruiting | Sohag University | 30 | 2026-07-12 | 2026-07-13 |
| Efficacy of Combined Endoscopic Third Ventriculostomy and Choroid Plexus Cauterization in Treatment of Hydrocephalus Combined endoscopic third ventriculostomy & coroid plexus cauterization - Paediatric Hydrocephalus | Not applicable | Not yet recruiting | Assiut University | 90 | 2026-07-01 | 2026-07-30 |
| Strategies for Weaning From External Ventricular Drainage Direct clamping of external ventricular drain, Progressive (gradual) weaning of external ventricular drain - Subarachnoid Hemorrhage, Hydrocephalus | Not applicable | Not yet recruiting | University Hospital, Angers | 170 | 2026-07-01 | 2026-06-05 |
| Study of Shunt Flow Under Different Valve Settings Using a Wireless Sensor Rhaeos Shunt Monitoring System (RSMS), ShuntCheck III - Hydrocephalus | Not applicable | Not yet recruiting | Rhaeos, Inc. | 85 | 2026-06-30 | 2026-07-01 |
| UVC in Prevention of Surgical Wound Infection UVC Irradiation - Hydrocephalus | Not applicable | Not yet recruiting | Ville Leinonen | 75 | 2026-06-04 | 2026-05-20 |
| Examining the Feasibility of Using Pressure Gradient Regulated Automated Cerebral Spinal Fluid Drainage During External Lumbar Drain Trials Intellidrop Automated CSF Drainage System - NPH (Normal Pressure Hydrocephalus) | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 10 | 2026-05-14 | 2026-06-02 |
| Ultrasound (US) Guided External Ventricular Catheter Placement Catheter Placement with Solopass System - Hydrocephalus | Not applicable | Recruiting | Milton S. Hershey Medical Center | 10 | 2026-04-01 | 2026-06-05 |
| Simultaneous Vs Staged VPS and CP :A Multi-cnter RCT. Time of choosing VPS and VP - Ventriculoperitoneal Shunt (VPS), Cranioplasty | Not applicable | Not yet recruiting | Anhui Provincial Hospital | 300 | 2026-04-01 | 2026-03-10 |
| Cefazolin Antibiotic Prophylaxis in Ventricular Shunt Surgery: Determination of Cerebrospinal Fluid Concentration During Valve Implantation Cefazolin antibiotic prophylaxis - Hydrocephaly, CSF Shunts | Not applicable | Recruiting | University Hospital, Strasbourg, France | 15 | 2026-02-01 | 2026-08-20 |
| Flow Detection in Open and Closed Shunt Valve Periods Rhaeos Shunt Monitoring System - Hydrocephalus | Not applicable | Recruiting | Rhaeos, Inc. | 55 | 2026-01-27 | 2026-03-18 |
| Assessment of CSF Shunt Flow During Activities of Daily Living and Sleep With a Thermal Measurement Device wireless thermal anisotropy measurement device - Hydrocephalus | Not applicable | Recruiting | Rhaeos, Inc. | 28 | 2025-11-10 | 2026-08-25 |
| Non-invasive Diagnostics of Shunt Obstruction in Adult Hydrocephalus Intervention group "Virtual OFF", Control group (no change in shunt setting) - Normal Pressure Hydrocephalus Patients, Normal Pressure Hydrocephalus | Not applicable | Not yet recruiting | Göteborg University | 60 | 2025-09-15 | 2025-09-15 |
| Analysis of Cerebrospinal Fluid Dynamics in Normal Pressure Hydrocephalus Cerebrospinal fluid drainge - Normal Pressure Hydrocephalus | Not applicable | Recruiting | Chungnam National University Hospital | 22 | 2025-09-11 | 2026-09-21 |
| Assessment of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device in Asymptomatic Patients Thermal Anisotropy Measurement Device - Hydrocephalus | Not applicable | Not yet recruiting | Rhaeos, Inc. | 60 | 2025-06-01 | 2025-05-15 |
| Assessment of CSF Shunt Flow and Headaches With a Thermal Measurement Device wireless thermal anisotropy measurement device - Hydrocephalus | Not applicable | Recruiting | Rhaeos, Inc. | 29 | 2025-05-02 | 2025-05-30 |
| Light Therapy Device for Neonatal Intraventricular Hemorrhage Grade 3 and 4 Low Level Laser Therapy for Intraventricular Hemorrhage of Prematurity - Intraventricular Hemorrhage of Prematurity, Hydrocephalus | Not applicable | Recruiting | Rutgers, The State University of New Jersey | 24 | 2025-02-25 | 2025-07-22 |
| Assessment of CSF Shunt Flow in an Outpatient Setting with a Thermal Measurement Device wireless wearable thermal anisotropy measurement device - Hydrocephalus | Not applicable | Completed | Rhaeos, Inc. | 20 | 2024-12-10 | 2025-02-10 |
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Hydrocephalus, Normal Pressure (26) · Subarachnoid Hemorrhage (7) · Brain Neoplasms (5) · Intracranial Hypertension (5) · Brain Injuries (3) · Anxiety Disorders (2) · Brain Diseases (2) · Brain Edema (2) · Brain Injuries, Traumatic (2) · Consciousness Disorders (2) · Surgical Wound Infection (2) · Alzheimer Disease (1) · Aneurysm (1) · Arnold-Chiari Malformation (1)
Central Nervous System Diseases (88) · Nervous System Diseases (87) · Brain Diseases (86) · Pathological Conditions, Signs and Symptoms (17) · Pathologic Processes (13) · Cardiovascular Diseases (11) · Vascular Diseases (11) · Cerebrovascular Disorders (8) · Hemorrhage (7) · Intracranial Hemorrhages (7) · Mental Disorders (6) · Neoplasms (6) · Neoplasms by Site (6) · Nervous System Neoplasms (6)
Ventriculoperitoneal Shunt (6) · Ventriculostomy (5) · Cerebrospinal Fluid Shunts (2) · Anesthesia, General (1) · Cerebrovascular Circulation (1) · Control Groups (1) · Drainage (1) · Drug Implants (1) · Educational Status (1) · Hydrodynamics (1) · Hypnosis (1) · Low-Level Light Therapy (1) · Mannitol (1) · Occupational Therapy (1) · Patient Discharge (1)
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PMID 40135887, PMID 41734937, PMID 10195493, PMID 11077095, PMID 1114545, PMID 17041512, PMID 17330548, PMID 18092331, PMID 18092336, PMID 18173315, PMID 18282655, PMID 18402070, PMID 19388301, PMID 19713705, PMID 19934980, PMID 20097391, PMID 22038765, PMID 23250963, PMID 23330995, PMID 23415160, PMID 23510566, PMID 24118122, PMID 24330776, PMID 24379955, PMID 24729303, PMID 25480528, PMID 26003249, PMID 26578001, PMID 27490149, PMID 28892272, PMID 28973670, PMID 30792248, PMID 31141553, PMID 31997040, PMID 32001008, PMID 32484029, PMID 33455998, PMID 3351510, PMID 34011396, PMID 34809666, PMID 34862267, PMID 35325129, PMID 35418936, PMID 37165711, PMID 37976516, PMID 38698559, PMID 38773608, PMID 39010208, PMID 40486963, PMID 42363276
2019 (1), 5UG3NS130338 (1), R01EB004632 (1), R44NS074486 (1), U01NS107486 (1)