23 completed, 8 unknown, 5 terminated, 4 not yet recruiting. 10 Phase 3, 8 Not applicable, 7 Phase 2, 1 Phase 1, 1 Phase 4.
Follow Hemorrhagic Shock: new trials by email Literature Review of Hemorrhagic Shock trials Research Report on Hemorrhagic Shock
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Resuscitation on Gastric Emptying Using POCUS in Pediatric Trauma Patients Hemorrhagic Shock, Pediatric Trauma | Not yet recruiting | Assiut University | 50 | 2026-10-01 | 2026-09-09 | |
| Inferior Vena Cava Versus Subclavian Vein Collapsibility for Predicting Fluid Responsiveness in Trauma Hemorrhagic Shock Hemorrhagic Shock, Trauma | Not yet recruiting | Assiut University | 120 | 2026-10-01 | 2026-09-14 | |
| Cryo-FIRST: Effectiveness of INTERCEPT Fibrinogen Complex (IFC) for Trauma-Associated Hemorrhage Pathogen Reduced Cryoprecipitated Fibrinogen Complex - Hypofibrinogenemia, Hemorrhage | Enrolling by invitation | Cerus Corporation | 320 | 2026-09-15 | 2026-10-14 | |
| Hemorrhagic Shock in Orthopedic Fractures Hemorrhagic Shock, Pelvic Fractures | Not yet recruiting | Sohag University | 250 | 2026-07-25 | 2026-07-10 | |
| Optimization Strategies for Blood Transfusion Protocols in the Emergency Treatment of Hemorrhagic Shock low-titer O-group whole blood, 1:1:1 component transfusion, ABO- and Rh-compatible whole blood - Hemorrhage, Hemorrhagic Shock | Phase 3 | Not yet recruiting | Xijing Hospital | 180 | 2025-09-01 | 2025-08-19 |
| REVIVE: Reducing Exsanguination Via In-Vivo Expandable Foam ResQFoam - Hemorrhagic Shock, Trauma | Not applicable | Recruiting | Arsenal Medical, Inc. | 40 | 2025-08-07 | 2025-11-10 |
| Biological and Clinical Relevance of Quantra Viscoelastic Hemostatic Assay in Hemorrhagic Cardiac Surgery Viscoelastometric hemostatic assay - Hemorrhage, Cardiac Surgery | Completed | Pitié-Salpêtrière Hospital | 600 | 2025-07-10 | 2026-04-20 | |
| Massive Transfusion in Children-2: A Trial Examining Life Threatening Hemorrhage in Children Low Titer Group O Whole Blood (LTOWB), Placebo, Tranexamic Acid (TXA) - Hemorrhagic Shock, Trauma Injury | Phase 3 | Recruiting | Philip Spinella | 1000 | 2024-11-01 | 2026-09-17 |
| Low Dose of Norepinephrine Within 24-Hour Mortality in Traumatic Patient With Hemorrhagic Shock Crystalloid and blood as resuscitation, crystalloid, blood and low dose of norepinephrine - Mortality Rate, Hemorrhagic Shock | Not applicable | Completed | Tanta University | 60 | 2024-08-30 | 2025-07-11 |
| Evaluation of Endothelial Glycocalyx in the Surgical Resuscitation of Major Burn Patients Debridement Surgery, Sdc-1 Level Measurement - Syndecan 1, Severe Burn | Recruiting | Hospital Universitari Vall d'Hebron Research Institute | 40 | 2024-03-05 | 2024-11-01 | |
| Norepinephrine in Preperiod of Hypotensive Resuscitation in Hemorrhagic Shock Low dose of Norepinephrine (NE), High dose of Norepinephrine (NE) - Norepinephrine, Hemorrhagic Shock | Not applicable | Unknown | Tanta University | 200 | 2023-12-01 | 2024-03-15 |
| Prospective Validation of the SHOCKMATRIX Hemorrhage Predictive Model Ambispective validation of machine learning-based predictive model - Wounds and Injuries, Traumatic Shock | Completed | Assistance Publique - Hôpitaux de Paris | 1584 | 2022-07-01 | 2025-02-18 | |
| Type O Whole Blood and Assessment of Age During Prehospital Resuscitation Trial low titer whole blood, Standard Care - Hemorrhagic Shock, Traumatic Injury | Phase 3 | Completed | Jason Sperry | 1020 | 2022-04-19 | 2026-02-12 |
| Low-Titer O Positive Whole Blood Versus Component Therapy for Emergent Transfusion in Trauma Patients Routine labs - Hemorrhagic Shock, Acute Blood Loss Anemia | Phase 3 | Completed | Loma Linda University | 199 | 2022-03-05 | 2025-08-08 |
| Detection of Exhaled Methane Levels in Hemorrhagic Shock Measurement of methane concentrations in exhaled breath, Videomicroscopy of the sublingual microcirculation, Blood gas and laboratory analysis - Hemorrhagic Shock, Trauma | Unknown | Szeged University | 40 | 2021-11-01 | 2021-09-28 | |
| A 48 Subject Study Using Non-invasive Multi-Technology Measurements for Early Detection of Ongoing Hemorrhage Occult Bleeding, Hemorrhage | Terminated | Dartmouth-Hitchcock Medical Center | 7 | 2021-02-01 | 2022-01-05 | |
| Predictors Of Stroke Outcome In Chidren Brain magnetic resonance imaging (MRI) , computed tomography (CT) - Ischemic Stroke, Hemorrhagic Shock | Unknown | Assiut University | 30 | 2020-12-01 | 2020-04-02 | |
| Philadelphia Immediate Transport in Penetrating Trauma Trial Advanced Life Support - Hemorrhagic Shock, Peritonitis | Not applicable | Withdrawn | Temple University | 2020-02-01 | 2022-07-28 | |
| Blood Transfusion by Boston MedFlight Registry Hemorrhagic Shock | Unknown | Massachusetts General Hospital | 500 | 2019-11-01 | 2021-09-01 | |
| Pragmatic Prehospital Group O Whole Blood Early Resuscitation Trial Whole blood - Hemorrhagic Shock | Phase 3 | Terminated | Jason Sperry | 86 | 2018-11-20 | 2021-10-06 |
Showing 20 of 47. Sign in to see all of them.
Shock, Hemorrhagic (47) · Wounds and Injuries (15) · Hemorrhage (7) · Brain Injuries, Traumatic (5) · Shock (5) · Hemostatic Disorders (4) · Shock, Traumatic (4) · Accidental Injuries (3) · Multiple Trauma (3) · Hypovolemia (2) · Wounds, Nonpenetrating (2) · Wounds, Penetrating (2) · Acidosis, Lactic (1) · Afibrinogenemia (1) · Blood Coagulation Disorders (1)
Pathologic Processes (47) · Pathological Conditions, Signs and Symptoms (47) · Shock (42) · Hemorrhage (40) · Wounds and Injuries (10) · Brain Diseases (7) · Central Nervous System Diseases (7) · Nervous System Diseases (7) · Cardiovascular Diseases (6) · Vascular Diseases (6) · Brain Injuries (5) · Craniocerebral Trauma (5) · Hematologic Diseases (5) · Hemic and Lymphatic Diseases (5) · Hemorrhagic Disorders (5)
Norepinephrine (3) · Standard of Care (3) · Tranexamic Acid (3) · Erythrocyte Count (2) · Resuscitation (2) · Ringer's Lactate (2) · Saline Solution (2) · Sodium Chloride (2) · Blood Cell Count (1) · Blood Gas Analysis (1) · Blood Specimen Collection (1) · Control Groups (1) · Crystalloid Solutions (1) · Dextrans (1) · Glutamine (1)
Assiut University (4) · Assistance Publique - Hôpitaux de Paris (2) · Haukeland University Hospital (2) · Jason Sperry (2) · Tanta University (2) · University of California, San Francisco (2) · University of Washington (2) · Arrowhead Regional Medical Center (1) · Arsenal Medical, Inc. (1) · Baylor College of Medicine (1) · Cerus Corporation (1) · Cristina Martinez (1) · Dartmouth-Hitchcock Medical Center (1) · Denver Health and Hospital Authority (1) · Hospital Universitari Vall d'Hebron Research Institute (1)
United States (20) · Canada (5) · Egypt (4) · France (4) · Norway (3) · China (2) · Germany (2) · Spain (2) · Australia (1) · Austria (1) · Belgium (1) · Brazil (1) · Hungary (1) · Indonesia (1) · Iran (1)
Amy Goldberg, MD (1) · Charles Van Way, III, M.D. (1) · David Hoyt, MD (1) · David T Neilipovitz, MD (1) · Eileen M Bulger, MD (1) · Ernest E Moore, MD (1) · Frank V. Booth, BCh, FACS (1) · Geoffrey T Manley, MD, PhD (1) · Geoffroy Hariri, MD (1) · Gordon D Rubenfeld, MD, MSc (1) · Hanne Klausen, MD (1) · Hassan Kotb, professor (1) · Homer C Tien, MD, MSc (1)
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R34HL135224 (1), U01HL077863 (1)