13 completed, 5 unknown, 4 terminated, 1 recruiting. 7 Phase 3, 6 Not applicable, 5 Phase 4, 4 Phase 2, 2 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 7 | Completed 4, Unknown 2, Terminated 1 |
| Not applicable | 6 | Completed 3, Unknown 3 |
| Phase 4 | 5 | Completed 4, Terminated 1 |
| Phase 2 | 4 | Completed 3, Terminated 1 |
| Phase 1 | 2 | Completed 1, Terminated 1 |
Follow Dextrans: new trials by email Literature Review of Dextrans trials Research Report on Dextrans
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Renal Hemodynamics, Energetics and Insulin Resistance: A Follow-up Study Aminohippurate Sodium Inj 20%, Iohexol Inj 300 MG/ML, Dextran 40 - Type 2 Diabetes, Diabetes Type 2 | Completed | University of Colorado, Denver | 57 | 2022-09-30 | 2026-08-24 | |
| Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study) Aminohippurate Sodium Inj 20%, Iohexol Inj 300 MG/ML, Dextran 40 - Type 2 Diabetes Mellitus, Diabetic Kidney Disease | Recruiting | Petter Bjornstad | 100 | 2021-09-27 | 2025-03-24 | |
| Sjögren's Syndrome Is Associated With Meibomian Gland Dysfunction liposic, Tears Naturale Forte - Meibomian Gland Dysfunction, Sjögren's Syndrome | Not applicable | Unknown | LanZhou University | 60 | 2018-02-10 | 2018-02-15 |
| Effects of Two Tear Substitutes in Patients With Dry Eye Syndrome Liposic, Tears Naturale Forte - Dry Eye, Tear Film | Not applicable | Completed | Huaxia Eye Hospital Group | 95 | 2017-07-01 | 2018-02-26 |
| Is Sjögren's Syndrome Associated With Meibomian Gland Dysfunction ? Tears Naturale Forte, liposic - Sjögren's Syndrome, Meibomian Gland Dysfunction | Not applicable | Unknown | Tung Wah Hospital | 80 | 2017-05-01 | 2017-05-16 |
| Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit Riboflavin, Dextran, UVA Light Source - Keratolysis | Phase 1 / Phase 2 | Completed | Joseph B. Ciolino, MD | 76 | 2017-03-15 | 2023-05-10 |
| Comparison of the Clinical Effects of Two Tear Substitutes in Patients With Dry Eye Syndrome Liposic, Tears Naturale Forte - Dry Eye | Not applicable | Unknown | Sun Yat-sen University | 50 | 2016-12-01 | 2016-12-15 |
| Dextran, a Plasma Expander, Offers New Hope for Patients With Decompensated Liver Cirrhosis and Acute Kidney Injury Dextran 40 - Cirrhosis, Liver, AKI | Phase 2 / Phase 3 | Completed | Ramathibodi Hospital | 10 | 2015-07-01 | 2017-03-03 |
| Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism riboflavin ophthalmic solution, 0% dextran, UVA Irradiation (30 mW/cm2 for 2 minutes continuous UVA), UVA Irradiation (30 mW/cm2 for 3 minutes pulsed UVA with an on/off cycle of 2 seconds UVA on/1 second UVA off) - Hyperopia, Hyperopic Astigmatism | Phase 1 / Phase 2 | Terminated | Glaukos Corporation | 2 | 2013-08-01 | 2021-04-26 |
| Phase 3 Study to Evaluate the Efficacy & Safety of Self-Administered Injections of BMN165 by Adults With PKU BMN165 20mg/day, BMN165 40mg/day, Placebo - Phenylketonuria (PKU) | Phase 3 | Completed | BioMarin Pharmaceutical | 215 | 2013-07-29 | 2021-05-21 |
| A Study to Evaluate the Efficacy of Lastacaft® Compared to Pataday™ and Placebo in Patients With Acute Allergic Conjunctivitis Alcaftadine 0.25%, Olopatadine 0.2%, dextran 70 0.1%/hydroxypropyl methylcellulose 0.3% - Conjunctivitis, Allergic | Phase 4 | Completed | Allergan | 157 | 2012-11-01 | 2014-01-14 |
| Optical Imaging Measurement of Intravascular Solution Efficacy Trial Contrast Injection, Dextran Injection, CO2 Injection - Peripheral Artery Disease | Not applicable | Completed | University Hospitals Cleveland Medical Center | 23 | 2012-09-01 | 2022-09-21 |
| Transepithelial Corneal Collagen Crosslinking for Keratoconus and Corneal Ectasia Riboflavin - Keratoconus, Corneal Ectasia | Phase 3 | Unknown | Cornea and Laser Eye Institute | 160 | 2011-11-01 | 2023-02-08 |
| A Study to Evaluate the Duration of LASTACAFT® in Acute Allergic Conjunctivitis alcaftadine 0.25% ophthalmic solution, olopatadine 0.2% ophthalmic solution, dextran 70 0.1%/hydroxypropyl methylcellulose 0.3% - Conjunctivitis, Allergic | Phase 4 | Completed | Allergan | 127 | 2011-10-01 | 2013-02-21 |
| Blood-aqueous Barrier Changes After the Use of Timolol and Prostaglandin Analogues Fixed Combination in Pseudophakic Patients With POAG travoprost and timolol maleate fixed combination, latanoprost and maleate timolol fixed combination, bimatoprost and timolol maleate fixed combination - Uveitis, Anterior, Cystoid Macular Edema | Phase 4 | Completed | University of Campinas, Brazil | 69 | 2011-10-01 | 2013-11-07 |
| Life 4°C Versus Optisol in Corneal Storage Media Corneal donor storage in Optisol GS media solution, Life 4°C solution for cornea storage - Complications of Corneal Transplant | Phase 3 | Completed | University Hospitals Cleveland Medical Center | 64 | 2011-06-01 | 2022-04-18 |
| Assessment of Alcon's Ocular Image Quantification System Olopatadine hydrochloride, 0.1% ophthalmic solution (Patanol), Dextran 70 0.1%, hydroxypropyl methylcellulose 0.3% (Tears Naturale II) - Allergic Conjunctivitis | Phase 4 | Completed | Alcon Research | 13 | 2010-12-01 | 2012-12-18 |
| Corneal Collagen Crosslinking for Progressive Keratoconus and Ectasia Using Riboflavin/Dextran and Hypotonic Riboflavin Riboflavin/Dextran, Hypotonic Riboflavin - Keratoconus, Corneal Ectasia | Phase 3 | Unknown | Cornea and Laser Eye Institute | 160 | 2010-06-01 | 2023-02-08 |
| T-Cat Laser & Cross-linking for Keratoconus Excimer laser ablation, and collagen cross-linking - Keratoconus, Pellucid Marginal Degeneration | Not applicable | Completed | Moorfields Eye Hospital NHS Foundation Trust | 15 | 2008-10-01 | 2011-07-21 |
| Hypertonic Modulation of Inflammation Following Injury hypertonic saline - Hemorrhagic Shock, Traumatic Brain Injury | Terminated | University of Washington | 119 | 2007-11-01 | 2017-05-01 |
Showing 20 of 23. Sign in to see all of them.
Dry Eye Syndromes (4) · Brain Injuries, Traumatic (3) · Conjunctivitis, Allergic (3) · Keratoconus (3) · Brain Injuries (2) · Diabetes Mellitus, Type 2 (2) · Diabetic Nephropathies (2) · Meibomian Gland Dysfunction (2) · Pediatric Obesity (2) · Sjogren's Syndrome (2) · Astigmatism (1) · Fibrosis (1) · Glaucoma, Open-Angle (1) · Glucose Intolerance (1) · Hyperopia (1)
Allergan (2) · Cornea and Laser Eye Institute (2) · University Hospitals Cleveland Medical Center (2) · University of Washington (2) · Alcon Research (1) · BioMarin Pharmaceutical (1) · Glaukos Corporation (1) · Huaxia Eye Hospital Group (1) · Joseph B. Ciolino, MD (1) · LanZhou University (1) · Moorfields Eye Hospital NHS Foundation Trust (1) · Petter Bjornstad (1) · Ramathibodi Hospital (1) · Sun Yat-sen University (1) · Tung Wah Hospital (1)
United States (15) · China (4) · Canada (3) · Brazil (1) · United Kingdom (1)
Peter Hersh, MD (2) · Petter Bjornstad, MD (2) · Abhasnee Sobhonslidsuk, MD (1) · Alana M Santana, MD (1) · Chad K Rostron, MB BS (1) · Chi Zhang, MD.PhD (1) · Eileen M Bulger, MD (1) · Jonathan Lass, M.D. (1) · Joseph B. Ciolino, MD (1) · Myron L Weisfeldt, MD (1) · Patrick G Northup, M.D. (1) · Shaolin Du, MD,PhD (1) · Vikram S Kashyap, MD (1)
PMID 25260889, PMID 32557558, PMID 19930566, PMID 20082712, PMID 20924011, PMID 20953964, PMID 21841534, PMID 22777113, PMID 24088993, PMID 25072443, PMID 25625366, PMID 25784523, PMID 27385151, PMID 34826353, PMID 40411344
U01HL077863 (1)