6 completed, 2 not yet recruiting, 1 unknown. 5 Phase 2, 2 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 5 | Completed 3, Not yet recruiting 1, Unknown 1 |
| Phase 1 | 2 | Completed 2 |
| Phase 3 | 2 | Completed 1, Not yet recruiting 1 |
Follow emodepside: new trials by email Literature Review of emodepside trials Research Report on emodepside
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of a Single Dose of Emodepside Compared to a Single Dose of Albendazole in Adolescents and Adults Infected With Trichuris Incognita Emodepside, Albendazole 400 mg - Trichuris Infection | Phase 2 | Not yet recruiting | Jennifer Keiser | 100 | 2026-11-15 | 2026-08-14 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Not yet recruiting | Swiss Tropical & Public Health Institute | 315 | 2026-11-06 | 2026-08-14 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Completed | Swiss Tropical & Public Health Institute | 315 | 2025-11-25 | 2026-10-08 |
| Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis Emodepside - Strongyloides Stercoralis Infection, Strongyloidiasis | Phase 2 | Completed | Swiss Tropical & Public Health Institute | 202 | 2024-05-20 | 2024-11-20 |
| Efficacy and Safety of Emodepside in Adolescents and Adults Infected With Hookworm Emodepside, Albendazole 400mg - Hookworm Infections | Phase 2 | Completed | Jennifer Keiser | 320 | 2022-09-16 | 2023-06-15 |
| Emodepside Phase II Trial for Treatment of Onchocerciasis emodepside, matching placebo of emodepside, ivermectin - Onchocerciasis | Phase 2 | Unknown | Drugs for Neglected Diseases | 578 | 2021-08-30 | 2024-03-05 |
| Efficacy and Safety of Emodepside in Adults Infected With Trichuris Trichiura and Hookworm Emodepside - Trichuris Trichiura; Infection, Hookworm Infections | Phase 2 | Completed | Jennifer Keiser | 442 | 2021-08-02 | 2022-05-27 |
| Relative Bioavailability Study of Emodepside IR-tablets and Solution Emodepside (BAY 44-4400) - Filariasis | Phase 1 | Completed | Drugs for Neglected Diseases | 77 | 2017-10-26 | 2020-03-09 |
| First in Man Clinical Trial of Emodepside (BAY 44-4400) emodepside (BAY 44-4400), placebo - Healthy Volunteers | Phase 1 | Completed | Drugs for Neglected Diseases | 79 | 2015-12-01 | 2020-04-13 |
Ancylostomiasis (4) · Hookworm Infections (4) · Trichuriasis (4) · Filariasis (3) · Enterobiasis (2) · Helminthiasis (2) · Neglected Diseases (2) · Nematode Infections (2) · Onchocerciasis (2) · Parasitic Diseases (2) · Skin Diseases (2) · Skin Diseases, Infectious (2) · Skin Diseases, Parasitic (2) · Onchocerciasis, Ocular (1) · Secernentea Infections (1)
Drugs for Neglected Diseases (3) · Jennifer Keiser (3) · Swiss Tropical & Public Health Institute (3)
Tanzania (3) · United Kingdom (2) · Democratic Republic of the Congo (1) · Ghana (1) · Laos (1) · Philippines (1)
Jennifer Keiser, Professor (2) · Frederic Monnot (1) · Jeremy Dennison (1) · Malcolm Boyce, MD, BSc (1) · Said Mohammed Ali, MSc (1)
PMID 37195942, PMID 37195949, PMID 39153818, PMID 40580974, PMID 41121745
2015 (1), 2017 (1)