5 completed, 1 not yet recruiting, 1 unknown. 4 Phase 1, 2 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 4 | Completed 4 |
| Phase 3 | 2 | Completed 1, Not yet recruiting 1 |
| Phase 2 | 1 | Unknown 1 |
Follow Bay 44-4400: new trials by email Literature Review of Bay 44-4400 trials Research Report on Bay 44-4400
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), Mebendazole 100 MG, similar placebo to mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Not yet recruiting | Swiss Tropical & Public Health Institute | 315 | 2026-11-06 | 2026-08-14 |
| Efficacy and Safety of Emodepside in Participants With Soil-transmitted Helminth Infections emodepside (BAY 44-4400), matching placebo of emodepside, Mebendazole - Trichuris Trichiura; Infection, Hookworm Infection | Phase 3 | Completed | Swiss Tropical & Public Health Institute | 315 | 2025-11-25 | 2026-10-08 |
| A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants BAY 44-4400 - Soil-transmitted Helminth Infection, Onchocerciasis (River Blindness) | Phase 1 | Completed | Bayer | 14 | 2024-05-07 | 2024-09-27 |
| Emodepside Phase II Trial for Treatment of Onchocerciasis emodepside, matching placebo of emodepside, ivermectin - Onchocerciasis | Phase 2 | Unknown | Drugs for Neglected Diseases | 578 | 2021-08-30 | 2024-03-05 |
| Safety, Tolerability and PK of Multiple-ascending Doses of Emodepside LSF emodepside (BAY 44-4400) or matching placebo - Filariasis | Phase 1 | Completed | Drugs for Neglected Diseases | 24 | 2017-11-14 | 2020-04-15 |
| Relative Bioavailability Study of Emodepside IR-tablets and Solution Emodepside (BAY 44-4400) - Filariasis | Phase 1 | Completed | Drugs for Neglected Diseases | 77 | 2017-10-26 | 2020-03-09 |
| First in Man Clinical Trial of Emodepside (BAY 44-4400) emodepside (BAY 44-4400), placebo - Healthy Volunteers | Phase 1 | Completed | Drugs for Neglected Diseases | 79 | 2015-12-01 | 2020-04-13 |
Filariasis (4) · Onchocerciasis (3) · Ancylostomiasis (2) · Enterobiasis (2) · Helminthiasis (2) · Hookworm Infections (2) · Neglected Diseases (2) · Nematode Infections (2) · Onchocerciasis, Ocular (2) · Parasitic Diseases (2) · Skin Diseases (2) · Skin Diseases, Infectious (2) · Skin Diseases, Parasitic (2) · Trichuriasis (2) · Secernentea Infections (1)
Drugs for Neglected Diseases (4) · Swiss Tropical & Public Health Institute (2) · Bayer (1)
United Kingdom (3) · Democratic Republic of the Congo (1) · Germany (1) · Ghana (1) · Philippines (1) · Tanzania (1)
Jennifer Keiser, Professor (2) · Frederic Monnot (1) · Jeremy Dennison (1) · Jeremy Dennison, PhD MBChB (1) · Malcolm Boyce, MD, BSc (1) · Said Mohammed Ali, MSc (1)
2017 (2), 2015 (1), 2023 (1)