23 completed, 11 unknown, 9 terminated, 2 not yet recruiting. 48 Phase 2, 13 Phase 3, 5 Phase 1.
Follow Healthcare-Associated Pneumonia: new trials by email Literature Review of Healthcare-Associated Pneumonia trials Research Report on Healthcare-Associated Pneumonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated Pneumonia colistimethate sodium, 0.9% Saline - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Not yet recruiting | University Hospital Fattouma Bourguiba | 400 | 2027-01-01 | 2026-10-08 |
| " Study of the Benefit of Nebulized Amikacin in the Treatment of Gram-negative Bacillus Pneumonia Acquired During Mechanical Ventilation in Patients Receiving Extracorporeal Membrane Veno-arterial Oxygenation " Amikacin, Standard of care - Pneumonia, Bacterial, Extracorporeal Membrane Oxygenation | Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 26 | 2026-08-10 | 2026-08-13 |
| Microbiome-guided Prophylaxis to Reduce Ventilator-Associated Pneumonia in Intensive Care Units: A Pilot Randomized Controlled Trial Microbiome-guided inhaled antibiotic prophylaxis, Placebo - Critical Illness, Mechanical Ventilation | Phase 2 | Not yet recruiting | University of Calgary | 70 | 2026-05-01 | 2026-03-11 |
| Phase 1/2a to Assess the Safety and Tolerability of TP-122A for the Treatment of Ventilator-Associated Pneumonia TP-122A - Pneumonia, Ventilator-Associated | Phase 1 / Phase 2 | Unknown | Technophage, SA | 15 | 2024-09-01 | 2024-04-17 |
| "Baricitinib for Treating Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype. Baricitinib 4 MG - Hospital-acquired Pneumonia | Phase 2 / Phase 3 | Unknown | Nantes University Hospital | 450 | 2023-07-01 | 2023-06-22 |
| Oro-nasal Decontamination to Prevent Ventilator-associated Pneumonia Povidone-Iodine, Saline spray - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Completed | Menoufia University | 78 | 2023-06-24 | 2023-11-27 |
| PK of BV100 in Patients VABP Suspected or Confirmed to Be Due to CRAB BV100 plus Polymyxin B, BAT - Ventilator Associated Pneumonia | Phase 2 | Completed | BioVersys AG | 39 | 2023-04-20 | 2025-01-14 |
| Use of Presepsin as a Marker for Immunotherapy Administration in Pneumonia Anakinra Prefilled Syringe, Placebo - Community-acquired Pneumonia, Hospital-acquired Pneumonia | Phase 2 | Completed | Hellenic Institute for the Study of Sepsis | 60 | 2023-03-06 | 2024-07-31 |
| Safety of Nebulized Combination Therapy BromAc® in COVID-19 Respiratory Disease Bromelains, Acetylcysteine - COVID-19 Pneumonia, COVID-19 | Phase 1 / Phase 2 | Unknown | Mucpharm Pty Ltd | 30 | 2022-05-01 | 2022-02-28 |
| Intravenous Metoprolol in Septic Shock Intravenous metoprolol tartrate, Standard Care (in control arm) - Septic Shock, Ventilator Acquired Pneumonia | Phase 2 | Completed | Alexandria University | 100 | 2022-04-01 | 2025-01-29 |
| A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants Cefiderocol, Standard of Care - Gram-negative Bacterial Infections, Bloodstream Infections (BSI) | Phase 2 | Completed | Shionogi | 53 | 2020-08-21 | 2026-02-27 |
| Vitamin C Infusion for the Treatment of Severe 2019-nCoV Infected Pneumonia VC, Sterile Water for Injection - Vitamin C, Pneumonia, Viral | Phase 2 | Terminated | ZhiYong Peng | 56 | 2020-02-14 | 2020-10-12 |
| Umbilical Cord(UC)-Derived Mesenchymal Stem Cells(MSCs) Treatment for the 2019-novel Coronavirus(nCOV) Pneumonia UC-MSCs - Pneumonia, Viral, Pneumonia, Ventilator-Associated | Phase 2 | Unknown | ZhiYong Peng | 16 | 2020-02-06 | 2020-07-01 |
| Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia EVAC-PU-ETT, PVC-ETT - Ventilator-acquired Pneumonia | Phase 2 | Completed | Yale University | 1074 | 2019-05-06 | 2024-09-24 |
| Coated Devices to Decrease Infection in the Intensive Care Unit Coated devices, Control - Critically Ill | Phase 1 / Phase 2 | Completed | Hospital do Coracao | 103 | 2019-04-06 | 2020-03-09 |
| Nebulized Aztreonam for Prevention of Gram Negative Ventilator-associated Pneumonia Aztreonam lysine, Aerogen Solo, CombiHaler - Ventilator Associated Pneumonia, Prevention | Phase 2 / Phase 3 | Terminated | Hospital Universitari Joan XXIII de Tarragona. | 9 | 2019-03-19 | 2021-07-01 |
| Low Versus High Corticosteroid Use in Ventilator Associated Pneumonia methylprednisolone, Methyl Prednisolonate, ventilators - Ventilator Associated Pneumonia | Phase 2 | Completed | King Abdul Aziz Specialist Hospital | 240 | 2018-01-02 | 2020-07-13 |
| Prevention of S. Aureus Pneumonia Study in Mechanically Ventilated Subjects Who Are Heavily Colonized With S. Aureus. ASN100, Placebo - Pneumonia, Ventilator-associated, Pneumonia, Staphylococcal | Phase 2 | Terminated | Arsanis, Inc. | 155 | 2016-11-01 | 2019-07-31 |
| The Effect of Colistin Inhalation on Ventilator Associated Pneumonia Colistin, Carbapenem + Aminoglycoside/ Quinolone - Ventilator Associated Pneumonia | Phase 2 / Phase 3 | Completed | Nourhan Hassan Osama Thuraya Mohamed | 40 | 2016-01-02 | 2018-08-09 |
| Atropine for Preventing Ventilator-Associated Pneumonia Atropine, Placebo - Ventilator-Associated Pneumonia | Phase 2 | Completed | Universidade de Passo Fundo | 40 | 2015-02-01 | 2016-03-10 |
Showing 20 of 48. Sign in to see all of them.
Pneumonia, Ventilator-Associated (42) · Pneumonia (18) · Pseudomonas Infections (5) · Pneumonia, Bacterial (4) · Sepsis (3) · Bacteremia (2) · Bacterial Infections (2) · COVID-19 (2) · Critical Illness (2) · Cross Infection (2) · Infections (2) · Pneumonia, Viral (2) · Respiratory Tract Infections (2) · Abdominal Abscess (1)
Disease Attributes (48) · Iatrogenic Disease (48) · Lung Diseases (48) · Pathologic Processes (48) · Pathological Conditions, Signs and Symptoms (48) · Respiratory Tract Diseases (48) · Cross Infection (46) · Infections (46) · Respiratory Tract Infections (46) · Pneumonia (30) · Bacterial Infections and Mycoses (13) · Bacterial Infections (11) · Inflammation (6) · Systemic Inflammatory Response Syndrome (6)
Colistin (3) · Doripenem (3) · Saline Solution (3) · Standard of Care (3) · Amikacin (2) · Ascorbic Acid (2) · Chlorhexidine (2) · Cilastatin, Imipenem Drug Combination (2) · Injections (2) · Polymyxin B (2) · Sodium Chloride (2) · Toothbrushing (2) · Vancomycin (2) · colistinmethanesulfonic acid (2) · ASN100 (1)
Hospital Universitari Joan XXIII de Tarragona. (2) · ZhiYong Peng (2) · Alexandria University (1) · Anbics Management-Services Ag (1) · Arpida AG (1) · Arsanis, Inc. (1) · Assistance Publique - Hôpitaux de Paris (1) · Association Pour La Promotion A Tours De La Reanimation Medicale (1) · BioVersys AG (1) · Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (1) · Daren K. Heyland (1) · General Hospital of Shenyang Military Region (1) · Groupe Hospitalier Pitie-Salpetriere (1) · Hellenic Institute for the Study of Sepsis (1) · Hospital do Coracao (1)
United States (13) · France (10) · Spain (7) · China (6) · Canada (4) · Hungary (4) · Russia (4) · Belgium (3) · Georgia (3) · Greece (3) · Ukraine (3) · Argentina (2) · Austria (2) · Brazil (2) · Chile (2)
Alexandre Biasi, MD/PhD (1) · Antoni Torres, MD PhD (1) · Christian Van Delden, MD (1) · Cindy L Munro, RN,ANP,PHD (1) · Cindy Munro, RN, ANP,PhD (1) · Daren Heyland, MD (1) · David Lye, MBBS, FRACP (1) · David Willms, MD (1) · Deborah J Cook, MD (1) · Evangelos Giamarellos-Bourboulis, MD PhD (1) · Evangelos Giamarellos-Bourboulis, MD, PhD (1) · Frank A. Scannapieco, DMD PhD (1) · Frank MP van Haren, MD, PhD (1)
PMID 18991508, PMID 19482956, PMID 19765321, PMID 20463812, PMID 21287306, PMID 23357775, PMID 24981955, PMID 25050644, PMID 25317722, PMID 26472037, PMID 27080532, PMID 27480757, PMID 27965798, PMID 28159015, PMID 29041861, PMID 30526610, PMID 32526149, PMID 32595159, PMID 32641343, PMID 36289153, PMID 38676438, PMID 39230271, PMID 41319662, PMID 41552367, PMID 8888088
R01NR007652 (2), 2016 (1), 2019 (1), R01DE014685 (1), R33HL138650 (1)